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MTTTATGGVHLVDHPLVQHKITLMRRKEASTNSFRRLAHEVSALMAYEVLRDTALQEVEVQTPMETTTGK VVDGKKLVFVSILRAGTGILEGLLEVVPSARVGHIGLYRDPKTLVAVEYYFKMPGDLHERDVVVLDPLLA TGNSAIAAVDRLREYHPKSIKFVCLLTCPEGIAAMAEAHPDVPIYTAAVDRELDEHGYILPGLGDVADRI FGTK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2976 | - | - | 100% (214) | uracil phosphoribosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1600 | upp | 3e-38 | 36.41% (206) | uracil phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3337c | upp | 2e-38 | 38.83% (206) | uracil phosphoribosyltransferase |
| M. gilvum PYR-GCK | Mflv_3259 | - | 1e-101 | 81.73% (208) | uracil phosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv3309c | upp | 2e-38 | 38.83% (206) | uracil phosphoribosyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3662c | - | 2e-33 | 33.49% (212) | Uracil phosphoribosyltransferase |
| M. marinum M | MMAR_1217 | upp | 3e-38 | 37.38% (206) | uracil phosphoribosyltransferase Upp |
| M. avium 104 | MAV_4285 | upp | 8e-37 | 37.25% (204) | uracil phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_3473 | upp | 9e-92 | 75.00% (208) | uracil phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_2261 | upp | 5e-41 | 39.32% (206) | PROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP |
| M. ulcerans Agy99 | MUL_2675 | upp | 5e-32 | 36.70% (188) | uracil phosphoribosyltransferase Upp |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3337c|M.bovis_AF2122/97 ----------------------------------------------MQVH
Rv3309c|M.tuberculosis_H37Rv ----------------------------------------------MQVH
MMAR_1217|M.marinum_M ----------------------------------------------MEVH
MUL_2675|M.ulcerans_Agy99 --------------------------------------------------
MAV_4285|M.avium_104 MRRRSAFCDFDFRATRPEYTNGGKAFPAGGQACQRGFARSLYTLDQMDVC
MAB_3662c|M.abscessus_ATCC_199 ----------------------------------------------MHVH
TH_2261|M.thermoresistible__bu ----------------------------------------------MKVR
Mvan_2976|M.vanbaalenii_PYR-1 ----------------------------------------MTTTATGGVH
Mflv_3259|M.gilvum_PYR-GCK ----------------------------------------MTN---GGVH
MSMEG_3473|M.smegmatis_MC2_155 ---------------------------------------------MGTLH
Mb3337c|M.bovis_AF2122/97 VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
Rv3309c|M.tuberculosis_H37Rv VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
MMAR_1217|M.marinum_M VIDHPLAAARLTALRDERTGNAAFRKALRELTLVLVYEATRAAPTESVAI
MUL_2675|M.ulcerans_Agy99 --------------MTKRTGNAAFRQALRELTLVPVYEATRAAPTESVAI
MAV_4285|M.avium_104 VIDHPLAAARLTVLRDERTDTAGFRAALRDLTLMLVYEASRDAPRKSVRI
MAB_3662c|M.abscessus_ATCC_199 VVEHPLAAARLTTLRDARSDNAAFRTALRDLTLMLVYEATGSVPVESSTV
TH_2261|M.thermoresistible__bu IVDHPLAATRLTTLRDARTDNATFRAALRDLTVMLVYEATRDIATDTIPV
Mvan_2976|M.vanbaalenii_PYR-1 LVDHPLVQHKITLMRRKEASTNSFRRLAHEVSALMAYEVLRDTALQEVEV
Mflv_3259|M.gilvum_PYR-GCK LIDHPLVQHKITLMRRKEASTNSFRRLVREVSAMMAYEVMRDVAVQEIEV
MSMEG_3473|M.smegmatis_MC2_155 LIDHPLVQHKLTLMRQKDLSSKGFRQLLNEISMLMAYEVLRDIPLHDVEI
.. ** .::: : **. . . :
Mb3337c|M.bovis_AF2122/97 RTPLAETVGSRLTK-PPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARD
Rv3309c|M.tuberculosis_H37Rv RTPLAETVGSRLTK-PPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARD
MMAR_1217|M.marinum_M RTPLAATTGLRLAN-PPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARN
MUL_2675|M.ulcerans_Agy99 RTPLAATTGLRLAN-PPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARN
MAV_4285|M.avium_104 RTPVAAAAGTRLVN-PPLLVPVLRAGLGMVDPAQAALPEAEVGFVGVARD
MAB_3662c|M.abscessus_ATCC_199 RTPVAETTGYRLAN-PPLLVPVLRAGLGMVDQAHALIPEARVGFVGMARD
TH_2261|M.thermoresistible__bu LTPLAETTGCRLAN-PPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARD
Mvan_2976|M.vanbaalenii_PYR-1 QTPMETTTGKVVDGKKLVFVSILRAGTGILEGLLEVVPSARVGHIGLYRD
Mflv_3259|M.gilvum_PYR-GCK ETPLGITTGNVMDGKKVVFVSVLRAGTGLLEGMLDVVPSARVGHIGLYRD
MSMEG_3473|M.smegmatis_MC2_155 ETPLEHMTGTVIDGKKLVFVSILRAGNGILDGMLSVVPNARVGHIGLYRD
**: .* : ::*.:**** *::: :*.*.**.:*: *:
Mb3337c|M.bovis_AF2122/97 EQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADI
Rv3309c|M.tuberculosis_H37Rv EQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADI
MMAR_1217|M.marinum_M EQTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDI
MUL_2675|M.ulcerans_Agy99 EQTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDI
MAV_4285|M.avium_104 EQTHRPVPYLAALPDKLAGRSVMVLDPMLATGGSMAHTLGLLQRRGATDI
MAB_3662c|M.abscessus_ATCC_199 EDTWQPTPYLESLPADLSAQPVFVLDPMLATGGSMVYTLELLHARGAADI
TH_2261|M.thermoresistible__bu EQTHRPVPYLESLPGDLSDRPVLVLDPMLATGGSMVHTLKLLQERNAVDI
Mvan_2976|M.vanbaalenii_PYR-1 PKTLVAVEYYFKMPGDLHERDVVVLDPLLATGNSAIAAVDRLREYHPKSI
Mflv_3259|M.gilvum_PYR-GCK PKIRVAVEYYFKMPGDLHERDLIVLDPLLATGNSAIAAIDRLREHRPKSI
MSMEG_3473|M.smegmatis_MC2_155 PKTLVAVEYYFKLPNDVAERDVVVVDPMLATGNSAVAAIDRVKEQRPRSI
. .. * :* .: :.*:**::***.* :: : . .*
Mb3337c|M.bovis_AF2122/97 TVLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLG
Rv3309c|M.tuberculosis_H37Rv TVLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLG
MMAR_1217|M.marinum_M TVLCVVAAPQGVAALEKAAP------NARLFTVAIDDGLNEEAYIVPGLG
MUL_2675|M.ulcerans_Agy99 TVLCVVAAPQGVSALEKAAP------NARLFTVAIDDGLNEEAYIVPGLG
MAV_4285|M.avium_104 TVLCVVAAPEGLAAVGETAP------DARVFTAAVDKGLNKAAYIVPGLG
MAB_3662c|M.abscessus_ATCC_199 TMLCVVAAPQGVTAIQECAERFGPSTSVRLFTATIDEGLNDAAYIVPGLG
TH_2261|M.thermoresistible__bu TALCVVAAPEGLAAVEQVRP------DLRLFTAAVDERLNEIAFIVPGLG
Mvan_2976|M.vanbaalenii_PYR-1 KFVCLLTCPEGIAAMAEAHP------DVPIYTAAVDRELDEHGYILPGLG
Mflv_3259|M.gilvum_PYR-GCK KFVCLVTCPEGVAALTGAHP------EVPIYTAAIDHGLDEHGFILPGLG
MSMEG_3473|M.smegmatis_MC2_155 KFVCLLTCPEGIAAVQEAHP------EVTIYTAAVDRALDEHGYIVPGLG
. :*:::.*:*::*: . ::*.::* *:. .:*:****
Mb3337c|M.bovis_AF2122/97 DAGDRQFGPR----------------------------------------
Rv3309c|M.tuberculosis_H37Rv DAGDRQFGPR----------------------------------------
MMAR_1217|M.marinum_M DAGDRQFGPR----------------------------------------
MUL_2675|M.ulcerans_Agy99 DAGDRQFGPR----------------------------------------
MAV_4285|M.avium_104 DAGDRQFGPNLFTSSAPSRPEAPAGRGRAAAKMPGRRSARSESPSSTSPS
MAB_3662c|M.abscessus_ATCC_199 DAGDRQFGPR----------------------------------------
TH_2261|M.thermoresistible__bu DAGDRQFGPR----------------------------------------
Mvan_2976|M.vanbaalenii_PYR-1 DVADRIFGTK----------------------------------------
Mflv_3259|M.gilvum_PYR-GCK DVGDRLFGTK----------------------------------------
MSMEG_3473|M.smegmatis_MC2_155 DAGDRIFGTK----------------------------------------
*..** **..
Mb3337c|M.bovis_AF2122/97 ----------
Rv3309c|M.tuberculosis_H37Rv ----------
MMAR_1217|M.marinum_M ----------
MUL_2675|M.ulcerans_Agy99 ----------
MAV_4285|M.avium_104 ARSRKAAPPA
MAB_3662c|M.abscessus_ATCC_199 ----------
TH_2261|M.thermoresistible__bu ----------
Mvan_2976|M.vanbaalenii_PYR-1 ----------
Mflv_3259|M.gilvum_PYR-GCK ----------
MSMEG_3473|M.smegmatis_MC2_155 ----------