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PVGELQDVFDGVQAQVPEGLADHLRTVALVDHHVHGTFTEAVDRATFEFSINEGSNDPVPTWMTQFDSPL GLSIRRWCAPLLGLPPRADGEVYWKRRCEFGPDELATTMLPAAGVSRWIVDTGFKGDRITPHRRLAELAG GQSSEIVRLERLAEDLLVDGGTAAEDFPDAMRSALARAAVDPVVVGTKTIVAYRTGFDIDWSRPTDADVV TRARELTARPGPPRIDDPILIAFGVHEAAAHQLPIQVHVGFGDRDLDLHRSDPLLLLPLLRTMPPVPVLL LHCYPFHRQAGYLAQAFDHVNFDVGLAINYLGARSTGLVAEALDTAPFAKQLYSSDAFGPPELHVLGSVL WRRAMGLVLGEWVRTGDCTEADAIRIVDMIGMTNAQRVYGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2917 | - | - | 100% (392) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1911 | - | 4e-87 | 44.92% (374) | hypothetical protein Mb1911 |
| M. gilvum PYR-GCK | Mflv_3318 | - | 3e-85 | 46.67% (375) | amidohydrolase 2 |
| M. tuberculosis H37Rv | Rv1879 | - | 4e-87 | 44.92% (374) | hypothetical protein Rv1879 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2764 | - | 2e-94 | 47.31% (372) | hypothetical protein MMAR_2764 |
| M. avium 104 | MAV_2828 | - | 6e-96 | 48.66% (374) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_0362 | - | 1e-156 | 70.91% (385) | amidohydrolase 2 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2988 | - | 9e-93 | 46.24% (372) | hypothetical protein MUL_2988 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1911|M.bovis_AF2122/97 ------------MADSAGSDLTRHTAEVPLIDQHVHGCWLTEGNRRRFEN
Rv1879|M.tuberculosis_H37Rv ------------MADSAGSDLTRHTAEVPLIDQHVHGCWLTEGNRRRFEN
MMAR_2764|M.marinum_M ------------MTESATSELARHIRDVALIDQHVHGCWLTAGERSRFEN
MUL_2988|M.ulcerans_Agy99 ------------MTESATSELARHIRDVALIDQHVHGCWLTAGERSRFEN
MAV_2828|M.avium_104 -------------MVSDTDALAEHIGAVSLIDQHVHGCWLTTGGRRRFEN
Mflv_3318|M.gilvum_PYR-GCK -----------------MSSLREHIEAVPLVDHHVHGCWLGRHDRAQFEN
Mvan_2917|M.vanbaalenii_PYR-1 MPVGELQDVFDGVQAQVPEGLADHLRTVALVDHHVHGTFTEAVDRATFEF
MSMEG_0362|M.smegmatis_MC2_155 ------MDVFDGVENEVPGELAERLRTVGLIDHHVHGASAVRVGRAEFEA
* : * *:*:**** * **
Mb1911|M.bovis_AF2122/97 ALNEANTEPLADFDSGFDSQLGFAVRNHCAPILGLPRHVDPQTYWDRRSQ
Rv1879|M.tuberculosis_H37Rv ALNEANTEPLADFDSGFDSQLGFAVRNHCAPILGLPRHVDPQTYWDRRSQ
MMAR_2764|M.marinum_M ALNEANTQPLADFDSAFDSQLGFALRKHCGPILGLPEHVDPQTYWEHRSQ
MUL_2988|M.ulcerans_Agy99 ALNEANTQPLADFDSAFDSQLGFALRKHCGPILGLPEHVDPKTYWEHRSQ
MAV_2828|M.avium_104 ALNEANTEPITG--SGFDSQLGFAVRAHCAPILGLPRHADPQSYWERRCQ
Mflv_3318|M.gilvum_PYR-GCK ALNEADTAPLAEFDSAFDTQLGFAVRAHCAQTVGLERHCGADEYWNARAR
Mvan_2917|M.vanbaalenii_PYR-1 SINEGSNDPVPTWMTQFDSPLGLSIRRWCAPLLGLPPRADGEVYWKRRCE
MSMEG_0362|M.smegmatis_MC2_155 SINEASTAPVPEFMTQFDSPLGLSIRRWCAPVLGLPAHASADEYFARRSE
::**... *:. : **: **:::* *. :** : . . *: *..
Mb1911|M.bovis_AF2122/97 FSEAELARRFLQAAGVTDWLVETGIGY-DVSGMASVAGLGELSGSHAHEV
Rv1879|M.tuberculosis_H37Rv FSEAELARRFLQAAGVTDWLVETGIGY-DVSGMASVAGLGELSGSHAHEV
MMAR_2764|M.marinum_M FSEAELAERFLAAAGVTDWLVDTGING-DVAGPAELS---ALSRGRAHEV
MUL_2988|M.ulcerans_Agy99 LGETELAERFLAAAGVTDWLVDTGIDS-DVAGPAELS---ALSGGRAHEV
MAV_2828|M.avium_104 LSEHELARLFLPAAGVCNWLVDTGIGHGVVAGVAEMA---ELAAAPTAEL
Mflv_3318|M.gilvum_PYR-GCK IDEDVLAQRFLGGAGVSDWIVDTGFAH-GVADPEQLAG---LGAGRVHEV
Mvan_2917|M.vanbaalenii_PYR-1 FGPDELATTMLPAAGVSRWIVDTGFKGDRITPHRRLA---ELAGGQSSEI
MSMEG_0362|M.smegmatis_MC2_155 FAPAELSSTLLAHAGVERWIVDTGFGTELITTPEQLA---ALSGRPASTI
: *: :* *** *:*:**: :: :: *. :
Mb1911|M.bovis_AF2122/97 VRLEQVAEQAVQA----SGDYASAFNEILRRRAAT--AVATKSILAYRGG
Rv1879|M.tuberculosis_H37Rv VRLEQVAEQAVQA----SGDYASAFNEILRRRAAT--AVATKSILAYRGG
MMAR_2764|M.marinum_M VRLEQVAEQAAQA----PGDYALAFQELLHQRMAT--AVGTKSILAYRGG
MUL_2988|M.ulcerans_Agy99 VRLEQVAEQAAQA----PGDYALAFQELLHQRMAT--AIGTKSILAYRGG
MAV_2828|M.avium_104 VRLEEVAEQAAHA----PGDYAAAFDEILAARAAG--AVGTKSILAYRGG
Mflv_3318|M.gilvum_PYR-GCK VRLESTAELAAAA----TGDYAAAFDELLDRQTRT--AVGTKSILAYRGG
Mvan_2917|M.vanbaalenii_PYR-1 VRLERLAEDLLVDGGTAAEDFPDAMRSALARAAVDPVVVGTKTIVAYRTG
MSMEG_0362|M.smegmatis_MC2_155 LRLERLAEELLES-HSGADDFVDRFRSALDAAAQSTDIVGTKTIAAYRTG
:*** ** . *: : . * :.**:* *** *
Mb1911|M.bovis_AF2122/97 FDGDLTEPPAAQVAEAAKRWRDR-GGVRLQDRVLLRFGLHQALRLGKPLQ
Rv1879|M.tuberculosis_H37Rv FDGDLTEPPAAQVAEAAKRWRDR-GGVRLQDRVLLRFGLHQALRLGKPLQ
MMAR_2764|M.marinum_M FDGDLTEPSPAQVAQAARRWRDC-GETRLSDRVLLRFGLHQALRLGKPLQ
MUL_2988|M.ulcerans_Agy99 FDGDLTEPSPAQVAQAAKRWRDC-GGTRLSDRVLLRFGLHQALRLGKPLQ
MAV_2828|M.avium_104 FDGDLSEPSATEVARAAARWREL-GGTRLRDRVLLRFGLHRALRLGKPLQ
Mflv_3318|M.gilvum_PYR-GCK FVGDLSDPSPREVADAAARWRDA-GGTRLTDRVLLRFGLHRALRIGKPLQ
Mvan_2917|M.vanbaalenii_PYR-1 FDIDWSRPTDADVVTRARELTARPGPPRIDDPILIAFGVHEAAAHQLPIQ
MSMEG_0362|M.smegmatis_MC2_155 FDIDWARPGDDDVAARARAAADGPGPLRLQDPVLVAFGVHEAAERGLPVQ
* * : * :*. * * *: * :*: **:*.* *:*
Mb1911|M.bovis_AF2122/97 FHVGFGDRDADLHKANPLYLLDFLRQSGNTPIVLLHCYPYEREAGYLAQA
Rv1879|M.tuberculosis_H37Rv FHVGFGDRDADLHKANPLYLLDFLRQSGNTPIVLLHCYPYEREAGYLAQA
MMAR_2764|M.marinum_M LHVGFGDRDCDLHKTNPLYLLDFLRQSGETPIVLLHCYPYEREAGYLAQA
MUL_2988|M.ulcerans_Agy99 LHIGFGDRDCDLHKTNPLYLLDFLRQSGETPIVLLHCYPYEREAGYLAQA
MAV_2828|M.avium_104 LHVGFGDRDCDLHKANPLLLLDFLHHSGDVPIVLLHCYPYEREAGYLAQA
Mflv_3318|M.gilvum_PYR-GCK VHVGFGDRDCDLHTANPIHLLDFLRMSGDTPVMLLHCYPYEREAGYLAQA
Mvan_2917|M.vanbaalenii_PYR-1 VHVGFGDRDLDLHRSDPLLLLPLLRTMPPVPVLLLHCYPFHRQAGYLAQA
MSMEG_0362|M.smegmatis_MC2_155 VHVGFGDRDLDLHRTDPLLLLPLLRCMAPVPVLLLHCYPFHRQAGYLAQA
.*:****** *** ::*: ** :*: .*::******:.*:*******
Mb1911|M.bovis_AF2122/97 FNNVYLDGGLSVHYLGARSPAFIGRLLELAPFRKIVYSSDGFGPAELHFL
Rv1879|M.tuberculosis_H37Rv FNNVYLDGGLSVHYLGARSPAFIGRLLELAPFRKIVYSSDGFGPAELHFL
MMAR_2764|M.marinum_M FNNVFVDGGLTVNYLGARAPEFIGRLMELAPLRKIVYSSDGFGPAELHYL
MUL_2988|M.ulcerans_Agy99 FNNVFVDGGLTVNYLGARAPEFIGRLLELASLRKIVHSSDGFGPAELHYL
MAV_2828|M.avium_104 FNNVYVDGGLSVNHLGARSPAFLARLLELAPFSKILYSSDGFGPAELHFL
Mflv_3318|M.gilvum_PYR-GCK FHNVYLDGGLSINHLGARSAAFIARLLEMAPFRKILYSSDGFGPAELHYL
Mvan_2917|M.vanbaalenii_PYR-1 FDHVNFDVGLAINYLGARSTGLVAEALDTAPFAKQLYSSDAFGPPELHVL
MSMEG_0362|M.smegmatis_MC2_155 FDHVHFDVGLAVNHLGTRSVGLVAEALETAPFAKQLYSSDAYGPPELHLL
*.:* .* **::::**:*: ::.. :: *.: * ::***.:**.*** *
Mb1911|M.bovis_AF2122/97 GATLWRSGIQRVLRGFVERDDWCETDALRVVDLIAHGTAARIYRLGDR--
Rv1879|M.tuberculosis_H37Rv GATLWRSGIQRVLRGFVERDDWCETDALRVVDLIAHGTAARIYRLGDR--
MMAR_2764|M.marinum_M GAALWRRGIHRVLHGFVQSGDWAEADAIRVVDLIGRGNAARIYRLDQKAN
MUL_2988|M.ulcerans_Agy99 GAALWRRGIHRVLHGFVQSGDWAEADAIRVVDLIGHDNAARIYQLEQKGD
MAV_2828|M.avium_104 GAVLWRRGIHRVLREFVEAGDWSRADAIRVVDLIARENAARLYGLAP---
Mflv_3318|M.gilvum_PYR-GCK GARLWRNGIGAAMQSFIDTGEWSEADATRVVDLIAHRNARRVYRLD----
Mvan_2917|M.vanbaalenii_PYR-1 GSVLWRRAMGLVLGEWVRTGDCTEADAIRIVDMIGMTNAQRVYGL-----
MSMEG_0362|M.smegmatis_MC2_155 GSVLWRRAMGLVLGGWVRAGDCTEIDAIRIVELIGAQNAARVYGLGR---
*: *** .: .: :: .: . ** *:*::*. .* *:* *
Mb1911|M.bovis_AF2122/97 -------
Rv1879|M.tuberculosis_H37Rv -------
MMAR_2764|M.marinum_M QTMSENS
MUL_2988|M.ulcerans_Agy99 QSMSKNS
MAV_2828|M.avium_104 -------
Mflv_3318|M.gilvum_PYR-GCK -------
Mvan_2917|M.vanbaalenii_PYR-1 -------
MSMEG_0362|M.smegmatis_MC2_155 -------