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SSQSAPVQVRGVSKRYGATTAVASLDLEVQTAEVFALLGPNGAGKTTTVEMCEGFMKPDSGSIRILGLDP IADNAEVRARTGVMLQGGGAYPAARAGEMLELVAAYAADPLDPQWLLDTLGLTDAARTTYRRLSGGQQQR LALACAVIGRPELVFLDEPTAGMDAHARIVVWELIDALRRDGVTVVLTTHQLAEAEELADRILIIDHGAA VATGTPAELMRSGAENQLRFRAPRMLDLSLLVAALPEAYRATETAPGEYLVEGHIDPQVLATVTAWCARL NVLATDMRVEQRSLEDVFLDLTGRELRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2730 | - | - | 100% (309) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3122 | - | 8e-42 | 35.35% (314) | daunorubicin resistance ABC transporter ATPase subunit |
| M. vanbaalenii PYR-1 | Mvan_4796 | - | 9e-38 | 32.80% (314) | daunorubicin resistance ABC transporter ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1493c | - | 1e-143 | 81.13% (302) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3680 | - | 1e-160 | 92.18% (307) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1458c | - | 1e-143 | 81.13% (302) | unidentified antibiotic-transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_00590 | - | 1e-137 | 77.41% (301) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2752 | - | 1e-132 | 79.23% (284) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2263 | - | 1e-145 | 83.06% (301) | antibiotic ABC transporter ATP-binding protein |
| M. avium 104 | MAV_3321 | - | 1e-146 | 84.11% (302) | ABC transporter, ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_3119 | - | 1e-154 | 88.24% (306) | ABC transporter, ATP-binding subunit |
| M. thermoresistible (build 8) | TH_0343 | - | 5e-72 | 88.74% (151) | PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN |
| M. ulcerans Agy99 | MUL_1859 | - | 1e-145 | 83.06% (301) | antibiotic ABC transporter ATP-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2730|M.vanbaalenii_PYR-1 ---MS----------SQSAPVQVRGVSKRYGATTAVASLDLEVQTAEVFA
Mflv_3680|M.gilvum_PYR-GCK ---MTSVSPGAVPDGSPSAPVVLRGVSKRYGSTTAVAGLDLVVERAEVFA
Mb1493c|M.bovis_AF2122/97 ---MN---RAPDT---PEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMA
Rv1458c|M.tuberculosis_H37Rv ---MN---RAPDT---PEVVLRLRGVCKRYGSITAVSNLDLDVHDAEVMA
MLBr_00590|M.leprae_Br4923 ---MSSACTVPET---PEVVIRLRGVCKHYGSILAVSNLDLDIHSAEVLA
MAV_3321|M.avium_104 --------------------MRLRGVSKHYGSTTAVRDLDLEVHAAEVLA
MMAR_2263|M.marinum_M ---MSSDPKYPAAGRGTEIVVRLRGVGKQYGSVTAVSNLDLEVRAAEVMA
MUL_1859|M.ulcerans_Agy99 -------------------MVRLRGVGKQYGSVTAVSNLDLEVRAAEVMA
MAB_2752|M.abscessus_ATCC_1997 -----------------------------------MDSLDLEVHAAQVFA
MSMEG_3119|M.smegmatis_MC2_155 MTPRSGRSDAASSTRSPDVPVLLRGVTKRYGSTTAVSELDLEVQRAEVLA
TH_0343|M.thermoresistible__bu ----------------------------------------------VIGR
:
Mvan_2730|M.vanbaalenii_PYR-1 LLGPNGAGKTTTVEMCEGFMKPDSGSIRILGLDPIADNAEVRARTGVMLQ
Mflv_3680|M.gilvum_PYR-GCK LLGPNGAGKTTTVEMCEGFIKPDAGSLRILGLDPIVDNAEVRARTGVMLQ
Mb1493c|M.bovis_AF2122/97 LLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQ
Rv1458c|M.tuberculosis_H37Rv LLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPITDNARLRARIGVMLQ
MLBr_00590|M.leprae_Br4923 LLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQ
MAV_3321|M.avium_104 LLGPNGAGKTTTVEMCEGFVRPDAGTLEVLGLDPIADNARLRPRIGVMLQ
MMAR_2263|M.marinum_M LLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQ
MUL_1859|M.ulcerans_Agy99 LLGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQ
MAB_2752|M.abscessus_ATCC_1997 LLGPNGAGKTTTVELCEGFLHPDEGTVEVLGMDPVAKNSAVRSRIGVMLQ
MSMEG_3119|M.smegmatis_MC2_155 LLGPNGAGKTTTVEMCEGFVRADAGSIRILGLDPIADNARLRERIGVMLQ
TH_0343|M.thermoresistible__bu RLGRPGR----------DHDLPEPG--EIIRAGPVVEXX-----------
** * .. .: * .:: .*:..
Mvan_2730|M.vanbaalenii_PYR-1 GGGAYPAARAGEMLELVAAYAADPLDPQWLLDTLGLTDAARTTYRRLSGG
Mflv_3680|M.gilvum_PYR-GCK GGGAYPAARAGEMLDLVAAYAADPLDPTWLLDTLGLTDAARTTYRRLSGG
Mb1493c|M.bovis_AF2122/97 GGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGG
Rv1458c|M.tuberculosis_H37Rv GGGGYPAARAGEMLDLVASYAANPLDPHWLLDTLGLTEAARTTYRRLSGG
MLBr_00590|M.leprae_Br4923 GGGGYPAARAGEMLNLVASYAADPLDPEWLLETLGLTDVARTTYRRLSGG
MAV_3321|M.avium_104 GGGGYPAARAGEMLNLVAAYAADPLDPAWLLDTLGLTDAARTTYRRLSGG
MMAR_2263|M.marinum_M GGGGYPAARAGEMLDLVASYAADPLDPRWLLDTLGLTDAARTTYRRLSGG
MUL_1859|M.ulcerans_Agy99 GGGGYPAARAGEMLDLVASYAADPLDPRWLLDTLGLTDAARTTYRRLSGG
MAB_2752|M.abscessus_ATCC_1997 GGGAYPTARASEMLGLVASYSANPLDPQWLLDTLGLTDAARTPYRRLSGG
MSMEG_3119|M.smegmatis_MC2_155 GGGGYPAARAGEMLDLVASYAADPLDPAWLMDTLGLTDSARTTYRRLSGG
TH_0343|M.thermoresistible__bu --------------------------------------------------
Mvan_2730|M.vanbaalenii_PYR-1 QQQRLALACAVIGRPELVFLDEPTAGMDAHARIVVWELIDALRRDGVTVV
Mflv_3680|M.gilvum_PYR-GCK QQQRLALACAVVGRPELVFLDEPTAGMDAHARIVVWELIDALRRDGVTVV
Mb1493c|M.bovis_AF2122/97 QQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVV
Rv1458c|M.tuberculosis_H37Rv QQQRLALACALVGRPQLVFLDEPTAGMDAHARVLVWELIDALRRDGVTVV
MLBr_00590|M.leprae_Br4923 QQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVV
MAV_3321|M.avium_104 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MMAR_2263|M.marinum_M QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MUL_1859|M.ulcerans_Agy99 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MAB_2752|M.abscessus_ATCC_1997 QQQRLALACALVGRPELVFLDEPTAGMDAHARLVVWELIDCLRRDGVSVV
MSMEG_3119|M.smegmatis_MC2_155 QQQRLALACAVVGRPELVFLDEPTAGMDAHARIVVWELIDALRRDGVTVV
TH_0343|M.thermoresistible__bu -------------------XDEPTAGMDAHARIVVWELIDALRRDGVTVL
********:***::****** ******:*:
Mvan_2730|M.vanbaalenii_PYR-1 LTTHQLAEAEELADRILIIDHGAAVATGTPAELMRSGAENQLRFRAPRML
Mflv_3680|M.gilvum_PYR-GCK LTTHQLSEAEELADRILIIDNGAAVATGTPAELMRNGAENQLRFRAPKML
Mb1493c|M.bovis_AF2122/97 LTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRL
Rv1458c|M.tuberculosis_H37Rv LTTHHLKEAEELADRLVIIDHGVTVAAGTPAELMRSGAKDQLRFTAPPRL
MLBr_00590|M.leprae_Br4923 LTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRL
MAV_3321|M.avium_104 LTTHQLKEAEELADRLVIIDHGATVAAGTPAELMRSGAKDQLRFSAPPRL
MMAR_2263|M.marinum_M LTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLRFTAPPRL
MUL_1859|M.ulcerans_Agy99 LTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLRFTAPPRL
MAB_2752|M.abscessus_ATCC_1997 LTTHHMKEAEELADQLMIIDHGSVVAAGTPSELMQSGAENQLRFAAPPRL
MSMEG_3119|M.smegmatis_MC2_155 LTTHQLTEAEELADRIVIIDHGVAVATGTPAELMRSGAENQLRFSAPRKL
TH_0343|M.thermoresistible__bu LTTHQLSEAEELADRIVIIDHGVAVAAGTPAELMRSGAENQLRFTAPPKL
****:: *******:::***:* :* ***:***:.**::**** ** *
Mvan_2730|M.vanbaalenii_PYR-1 DLSLLVAALPEAYRATETAPGEYLVEGHIDPQVLATVTAWCARLNVLATD
Mflv_3680|M.gilvum_PYR-GCK DLSLLVAALPEGYRATEPTAGEYLVEGHIDPQVLATVTAWCARLDVLATD
Mb1493c|M.bovis_AF2122/97 DLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATD
Rv1458c|M.tuberculosis_H37Rv DLSLLASALPEGYQATELTPGEYLVEGPVDPQVLATVTAWCAQIDVLATD
MLBr_00590|M.leprae_Br4923 DLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQINVLTTN
MAV_3321|M.avium_104 DLSLLSAALPEDYKATELTPGEYLVEGPVDPQVLATVTAWCARIDVLATD
MMAR_2263|M.marinum_M DLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCARIDVLATD
MUL_1859|M.ulcerans_Agy99 DLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCARIDVLATD
MAB_2752|M.abscessus_ATCC_1997 DLTLLTSALPEGYKATEVTPGEYRVEGVVDPQVLATVTAWCARMDVLTTD
MSMEG_3119|M.smegmatis_MC2_155 DLSLLVAALPEGYNAVEAAPGEYLVEGHIDPQVLATVTAWCARVNVLATD
TH_0343|M.thermoresistible__bu DLSLLVAALPEGYKATETSAGEYLVEGHIDPQVLATVTAWCAQHDVLATG
**:** **** *...* :.*** * * :******:******: :**:*.
Mvan_2730|M.vanbaalenii_PYR-1 MRVEQRSLEDVFLDLTGRELRK
Mflv_3680|M.gilvum_PYR-GCK MRVEQRSLEDVFLDLTGRELRK
Mb1493c|M.bovis_AF2122/97 MRVEQRSLEDVFLDLTGRKLRQ
Rv1458c|M.tuberculosis_H37Rv MRVEQRSLEDVFLDLTGRKLRQ
MLBr_00590|M.leprae_Br4923 MRVEQHSLEDVFLDLTGRKLR-
MAV_3321|M.avium_104 MRVEQRSLEDVFLDLTGRKLRQ
MMAR_2263|M.marinum_M MRVEQRSLEDVFLDLTGRKLRS
MUL_1859|M.ulcerans_Agy99 MRVEQRSLEDVFLDLTGRKLRS
MAB_2752|M.abscessus_ATCC_1997 LRVEKRSLEDVFLDLTGRELR-
MSMEG_3119|M.smegmatis_MC2_155 MRVEQRSLEDVFLDLTGRELRS
TH_0343|M.thermoresistible__bu MRVEQRSLEDVFLELTGRELRP
:***::*******:****:**