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VRENAATLMRIGMVCPYSFDVPGGVQSHVLQLANVFHSDGHDVSVLAPASPDADESLPDYVVSGGKAIPI PYNGSVARLRFGPATHRKVKKWLQQGQFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLSVF EPILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVASFASAPPLPGYPRPGGTVLFLGRFDEP RKGMSVLLGALPAVAERFADVEILVVGRGDEDQLRGDAGPLARHLRFLGQVDDAEKASAMRSADVYCAPN TGGESFGIVLVEAMAAGTAVVASDLDAFRRVLVDGDAGRLVAVDDSAALAEGLIEMLSDDAVRARYIECA TRAVQRYDWSVVARQIMRVYETVAGAGVKVQVES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2562 | - | - | 100% (384) | phosphatidylinositol alpha-mannosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5246 | - | 7e-19 | 26.29% (350) | glycosyl transferase, group 1 |
| M. vanbaalenii PYR-1 | Mvan_2096 | - | 1e-18 | 25.66% (378) | glycosyl transferase, group 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2642c | pimA | 1e-172 | 81.05% (380) | alpha-mannosyltransferase PIMA |
| M. gilvum PYR-GCK | Mflv_3834 | - | 0.0 | 89.10% (376) | phosphatidylinositol alpha-mannosyltransferase |
| M. tuberculosis H37Rv | Rv2610c | pimA | 1e-172 | 81.05% (380) | alpha-mannosyltransferase PIMA |
| M. leprae Br4923 | MLBr_00452 | - | 1e-162 | 76.06% (376) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_2894c | - | 1e-163 | 76.33% (376) | phosphatidylinositol alpha-mannosyltransferase |
| M. marinum M | MMAR_2092 | pimA | 1e-177 | 83.24% (376) | alpha-mannosyltransferase PimA |
| M. avium 104 | MAV_3486 | - | 1e-171 | 81.65% (376) | phosphatidylinositol alpha-mannosyltransferase |
| M. smegmatis MC2 155 | MSMEG_2935 | - | 1e-172 | 81.28% (374) | phosphatidylinositol alpha-mannosyltransferase |
| M. thermoresistible (build 8) | TH_1809 | - | 1e-176 | 82.89% (374) | ALPHA-MANNOSYLTRANSFERASE PIMA |
| M. ulcerans Agy99 | MUL_3252 | pimA | 1e-178 | 82.51% (383) | alpha-mannosyltransferase PimA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2562|M.vanbaalenii_PYR-1 ----------------MRENAATLMRIGMVCPYSFDVPGGVQSHVLQLAN
Mflv_3834|M.gilvum_PYR-GCK ------------------------MRIGMVCPYSFDVPGGVQSHVLQLAE
MSMEG_2935|M.smegmatis_MC2_155 ------------------------MRIGMVCPYSFDVPGGVQSHVLQLAE
TH_1809|M.thermoresistible__bu ------------------------VRIGMVCPYSFDVPGGVQAHVLQLAE
Mb2642c|M.bovis_AF2122/97 ------------------------MRIGMICPYSFDVPGGVQSHVLQLAE
Rv2610c|M.tuberculosis_H37Rv ------------------------MRIGMICPYSFDVPGGVQSHVLQLAE
MAV_3486|M.avium_104 ------------------------MRIGMVCPYSFDVPGGVQSHVLQLAE
MMAR_2092|M.marinum_M ------------------------MRIGMVCPYSFDVAGGVQSHVLQLAE
MUL_3252|M.ulcerans_Agy99 MAHVSATMVGRLVRCPPRAAAGALMRIGMVCPYSFDVAGGVQSHVLQLAE
MLBr_00452|M.leprae_Br4923 ------------------------MRIGMICPYSFDVPGGVQSHVLQLAE
MAB_2894c|M.abscessus_ATCC_199 ------------------------MRIGMVCPYSFDVPGGVQSHVVQLAE
:****:*******.****:**:***:
Mvan_2562|M.vanbaalenii_PYR-1 VFHSDGHDVSVLAPASPDADESLPDYVVSGGKAIPIPYNGSVARLRFGPA
Mflv_3834|M.gilvum_PYR-GCK VMRVDGHEVSVLAPASPDAQDSLPDYVVSGGRAVPIPYNGSVARLRFGPA
MSMEG_2935|M.smegmatis_MC2_155 VLRDAGHEVSVLAPASPHVK--LPDYVVSGGKAVPIPYNGSVARLRFGPA
TH_1809|M.thermoresistible__bu VMRARGHEVSVLAPFSPQVR--LPDYVVSGGRAVPIPYNGSVARLRFGPA
Mb2642c|M.bovis_AF2122/97 VMRTRGHLVSVLAPASPHAA--LPDYFVSGGRAVPIPYNGSVARLRFGPA
Rv2610c|M.tuberculosis_H37Rv VMRTRGHLVSVLAPASPHAA--LPDYFVSGGRAVPIPYNGSVARLRFGPA
MAV_3486|M.avium_104 VMRRRGHDVSVLAPASPHAV--LPGYVVSAGKAVPIPYNGSVARLRFGPA
MMAR_2092|M.marinum_M VMRARGHEVSVLAPASPHAA--LPDYVVSGGKAVPIPYNGSVARLRFGPA
MUL_3252|M.ulcerans_Agy99 VMRARGHEVSVLAPASPHAA--LPDYVVSGGKAVPIPYNGSVARLRFGPA
MLBr_00452|M.leprae_Br4923 VMRARGQQVRVLAPASPDVS--LPEYVVSAGRAIPIPYNGSVARLQFSPA
MAB_2894c|M.abscessus_ATCC_199 VMRDRGHHVSLLAPSSSDLE--LPEFVVSGGKAVPIPYNGSVARLRFGPA
*:: *: * :*** *.. ** :.**.*:*:***********:*.**
Mvan_2562|M.vanbaalenii_PYR-1 THRKVKKWLQQGQFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
Mflv_3834|M.gilvum_PYR-GCK THRLVKKWIQQGRFDVLHLHEPNAPSLSMLALNIASGPIVATFHTSTTKS
MSMEG_2935|M.smegmatis_MC2_155 THRKVKKWIAEGDFDVLHIHEPNAPSLSMLALQAAEGPIVATFHTSTTKS
TH_1809|M.thermoresistible__bu THRKVKKWLAEGQFDVLHLHEPNAPSLSMLALQAAEGPIVATFHTSTTKS
Mb2642c|M.bovis_AF2122/97 THRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
Rv2610c|M.tuberculosis_H37Rv THRKVKKWLAHGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
MAV_3486|M.avium_104 THRKVKKWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
MMAR_2092|M.marinum_M THRKVKKWLSEGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
MUL_3252|M.ulcerans_Agy99 THRKVKKWLSEGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKS
MLBr_00452|M.leprae_Br4923 VHSRVRRWLVDGDFDVLHLHEPNAPSLSMWALRVAEGPIVATFHTSTTKS
MAB_2894c|M.abscessus_ATCC_199 TYAKTRRWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTSTTKS
.: .::*: .* *****:********** ** *.**************
Mvan_2562|M.vanbaalenii_PYR-1 LTLSVFEPILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVAS
Mflv_3834|M.gilvum_PYR-GCK LTLSVFEPILRPMHEKIVGRIAVSDLARRWQMESLGSDAVEIPNGVDVGS
MSMEG_2935|M.smegmatis_MC2_155 LTLSVFQGILRPYHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVDVAS
TH_1809|M.thermoresistible__bu LTLSVFQGILRPYHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVAS
Mb2642c|M.bovis_AF2122/97 LTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDS
Rv2610c|M.tuberculosis_H37Rv LTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVDS
MAV_3486|M.avium_104 LTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGTDAVEIPNGVDVAS
MMAR_2092|M.marinum_M LTLTVFQSILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVGS
MUL_3252|M.ulcerans_Agy99 LTLTVFQSILRPMHEKIVGRIAVSDLARRWQMEALGSDAVEIPNGVDVGS
MLBr_00452|M.leprae_Br4923 LTLSVFQGVLRPWHEKIIGRIAVSDLARRWQMEALGSDAVEIPNGVNVDS
MAB_2894c|M.abscessus_ATCC_199 LTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALGSDAVEIPNGVDVRS
***:**: :*** ****:******:********:**:*********:* *
Mvan_2562|M.vanbaalenii_PYR-1 FASAPPLPGYPRPGGTVLFLGRFDEPRKGMSVLLGALPAVAERFADVEIL
Mflv_3834|M.gilvum_PYR-GCK FATAPLLPGYPRTGPTVLFLGRFDEPRKGMAVLLGALPAVVEPFPDVEIL
MSMEG_2935|M.smegmatis_MC2_155 FADAPLLDGYPREGRTVLFLGRYDEPRKGMAVLLAALPKLVARFPDVEIL
TH_1809|M.thermoresistible__bu FAEAPLLDGYPRPGRTVLFLGRYDEPRKGMAVLLGALPALVGRYPEIEIL
Mb2642c|M.bovis_AF2122/97 FASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLL
Rv2610c|M.tuberculosis_H37Rv FASAARLDGYPRQGKTVLFLGRYDEPRKGMAVLLDALPKVVQRFPDVQLL
MAV_3486|M.avium_104 FASAPRLDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLL
MMAR_2092|M.marinum_M FASSSCLDGYPRPGKTVLFLGRYDEPRKGMSVLLEALPKLVERFSDVQLL
MUL_3252|M.ulcerans_Agy99 FASSSCLDGYPRPGKTVLFLGRYDEPRKGMSVLLEALPKLVERFIDVQLL
MLBr_00452|M.leprae_Br4923 LSSAPQLAGYPRLGKTVLFLGRYDEPRKGMSVLLDALPGVMECFDDVQLL
MAB_2894c|M.abscessus_ATCC_199 FSGAPVLEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEIL
:: :. * **** * *******:******* **: *** : : ::::*
Mvan_2562|M.vanbaalenii_PYR-1 VVGRGDEDQLRGDAGPLARHLRFLGQVDDAEKASAMRSADVYCAPNTGGE
Mflv_3834|M.gilvum_PYR-GCK VVGRGDEDELRSQAGPLAGHLRFLGQVGDAEKASAMRSADVYCAPNTGGE
MSMEG_2935|M.smegmatis_MC2_155 IVGRGDEDELREQAGDLAGHLRFLGQVDDATKASAMRSADVYCAPHLGGE
TH_1809|M.thermoresistible__bu IVGRGDEQELRGKAGRYARHLRFLGQVDDATKASAMRSADVYCAPHIGGE
Mb2642c|M.bovis_AF2122/97 IVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGE
Rv2610c|M.tuberculosis_H37Rv IVGHGDADQLRGQAGRLAAHLRFLGQVDDAGKASAMRSADVYCAPNTGGE
MAV_3486|M.avium_104 VVGRGDEDQLRTQAGELVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGE
MMAR_2092|M.marinum_M IVGRGDEDELRDEAGELAEHMRFLGQVDDAGKASAMRSADVYCAPNTGGE
MUL_3252|M.ulcerans_Agy99 IVGRGDEDELRDEAGELAEHMRFLGQVDDAGKASAMRSADVYCAPNTGGE
MLBr_00452|M.leprae_Br4923 IVGRGDEEQLRSQAGGLVEHIRFLGQVDDAGKAAAMRSADVYCAPNIGGE
MAB_2894c|M.abscessus_ATCC_199 IVGRGDEAELRTQAGPLAKHLKFLGQVDDATKASAMRSADVYCAPNIGGE
:**:** :** .** . *::*****.** **:***********: ***
Mvan_2562|M.vanbaalenii_PYR-1 SFGIVLVEAMAAGTAVVASDLDAFRRVLVDGDAGRLVAVD----DSAALA
Mflv_3834|M.gilvum_PYR-GCK SFGIVLVEAMAAGTAVVASDLDAFRRVLDDGEAGRLVTVD----DSAALA
MSMEG_2935|M.smegmatis_MC2_155 SFGIVLVEAMAAGTAVVASDLDAFRRVLADGDAGRLVPVD----DADGMA
TH_1809|M.thermoresistible__bu SFGIVLVEAMAAGTAVVASELDAFRRVLLDGQAGRLVPVD----DPAALA
Mb2642c|M.bovis_AF2122/97 SFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALA
Rv2610c|M.tuberculosis_H37Rv SFGIVLVEAMAAGTAVVASDLDAFRRVLRDGEVGHLVPVDPPDLQAAALA
MAV_3486|M.avium_104 SFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGALVPVG----DGDALA
MMAR_2092|M.marinum_M SFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEIGRLVPVD----DSDALA
MUL_3252|M.ulcerans_Agy99 SFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEIGRLVPVD----DSDALA
MLBr_00452|M.leprae_Br4923 SFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGHLVPAG----DSAALA
MAB_2894c|M.abscessus_ATCC_199 SFGIVLVEAMAAGTAVVASSLDAFRRVLLDGTAGRLTPTG----DPDALA
**************.****.******** ** * *.... : .:*
Mvan_2562|M.vanbaalenii_PYR-1 EGLIEMLSDDAVRARYIECATRAVQRYDWSVVARQIMRVYETVAGAGVKV
Mflv_3834|M.gilvum_PYR-GCK QGLVEVLSDAAVRRRYIECATRAVARYDWSVVGKQIMRVYETVAGSGVKV
MSMEG_2935|M.smegmatis_MC2_155 AALIGILEDDQLRAGYVARASERVHRYDWSVVSAQIMRVYETVSGAGIKV
TH_1809|M.thermoresistible__bu QGLLEVLGDDALRQRYIEVAAEAVRRYDWSVVAGQIMRVYETVASAGAKV
Mb2642c|M.bovis_AF2122/97 DGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKV
Rv2610c|M.tuberculosis_H37Rv DGLIAVLENDVLRERYVAAGNAAVRRYDWSVVASQIMRVYETVAGSGAKV
MAV_3486|M.avium_104 DALIAVLEDDVLRDGYVAAGQAAVQRYDWSVVASQIMRVYETVAATGAKV
MMAR_2092|M.marinum_M AALIEVLDSQELRERYVAAGTEAVRRYDWSVVASQIMRVYETVAGAGVKV
MUL_3252|M.ulcerans_Agy99 AALIEVLDSQELRERYVAAGTEAVRRYDWSVVASQIMRVYETVAGAGVKV
MLBr_00452|M.leprae_Br4923 DALVALLRNDVLRERYVAAGAEAVRRYDWSVVASQIMRVYETVATSGSKV
MAB_2894c|M.abscessus_ATCC_199 AALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVYETVTASGARV
.*: :* . * : . * *******. *** *****: :* :*
Mvan_2562|M.vanbaalenii_PYR-1 QVES------------
Mflv_3834|M.gilvum_PYR-GCK RVES------------
MSMEG_2935|M.smegmatis_MC2_155 QVSGAANRDETAGESV
TH_1809|M.thermoresistible__bu RVAT------------
Mb2642c|M.bovis_AF2122/97 QVAS------------
Rv2610c|M.tuberculosis_H37Rv QVAS------------
MAV_3486|M.avium_104 EVAS------------
MMAR_2092|M.marinum_M QVAS------------
MUL_3252|M.ulcerans_Agy99 QVAS------------
MLBr_00452|M.leprae_Br4923 QVAS------------
MAB_2894c|M.abscessus_ATCC_199 KVDSW-----------
.*