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VDPEDTIVDRGVGDPDRLQRLWTPHRMTYIVDAVKPGSASSSEPFTDIPNMSDEDGLVVARGELVYAVLN LYPYNPGHLMVVPYRRVAELENLTEAESAELMAFTQKAIRVMKAVSRPHGFNVGLNLGTSAGGSLSEHLH MHVVPRWGGDANFITVIGDSKVIPQLLRDTRLLLATEWDNHK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2559 | - | - | 100% (182) | histidine triad (HIT) protein |
| M. vanbaalenii PYR-1 | Mvan_4456 | - | 2e-06 | 32.95% (88) | histidine triad (HIT) protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2645c | - | 2e-79 | 79.89% (179) | hypothetical protein Mb2645c |
| M. gilvum PYR-GCK | Mflv_3837 | - | 3e-99 | 95.05% (182) | histidine triad (HIT) protein |
| M. tuberculosis H37Rv | Rv2613c | - | 2e-79 | 79.89% (179) | hypothetical protein Rv2613c |
| M. leprae Br4923 | MLBr_00455 | - | 6e-81 | 80.11% (176) | hypothetical protein MLBr_00455 |
| M. abscessus ATCC 19977 | MAB_2897c | - | 3e-83 | 81.46% (178) | hypothetical protein MAB_2897c |
| M. marinum M | MMAR_2089 | - | 8e-80 | 79.21% (178) | hypothetical protein MMAR_2089 |
| M. avium 104 | MAV_3489 | - | 3e-81 | 80.11% (181) | diadenosine tetraphosphate |
| M. smegmatis MC2 155 | MSMEG_2932 | - | 2e-82 | 80.33% (183) | HIT family protein hydrolase |
| M. thermoresistible (build 8) | TH_1725 | - | 7e-82 | 81.01% (179) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3255 | - | 1e-80 | 79.78% (178) | hypothetical protein MUL_3255 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2559|M.vanbaalenii_PYR-1 -----MD-------PED---TIVDRGVGDPDRLQRLWTPHRMTYIVDAVK
Mflv_3837|M.gilvum_PYR-GCK -----MD-------PED---TIVDRGVGDPDRLQRLWTPHRMTYIADAVK
MSMEG_2932|M.smegmatis_MC2_155 ----MTD-------PDER--QIVDRGVGDPDHLQRLWTPHRMSYIAEAPM
MMAR_2089|M.marinum_M ----MTNEESAQ--PQDS--TILDRGVGERDHLERLWTPYRMNYLAEAPL
MUL_3255|M.ulcerans_Agy99 ----MTNEESAQ--PQDS--TILDRGVGERDHLERLWTPYRMNYLAEAPL
Mb2645c|M.bovis_AF2122/97 ----MSDEDRTDRATEDH--TIFDRGVGQRDQLQRLWTPYRMNYLAEAPV
Rv2613c|M.tuberculosis_H37Rv ----MSDEDRTDRATEDH--TIFDRGVGQRDQLQRLWTPYRMNYLAEAPV
MLBr_00455|M.leprae_Br4923 ----MSEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPV
MAV_3489|M.avium_104 ----MSDPEQAEQDAER---TILDRGVGEQDHLQRLWTPYRMTYLAEAPM
MAB_2897c|M.abscessus_ATCC_199 ----MTD--------QDS--TIIDRGVGDPDHLQRLWSPHRMSYIAEAVK
TH_1725|M.thermoresistible__bu VTAGHNNEGRDRELGDER--TIVDQGPGEPDHLQRLWTPHRMSYIAEAPK
: : *.* * *: *:*:***:*:**.*:.:*
Mvan_2559|M.vanbaalenii_PYR-1 -----PGSASSSEPFTDIPNMSDEDGLVVARGELVYAVLNLYPYNPGHLM
Mflv_3837|M.gilvum_PYR-GCK -----GGSAASSEPFSDIPNMSDEDGLVVARGDLVYAVLNLYPYNPGHLM
MSMEG_2932|M.smegmatis_MC2_155 KKRGEGGSAGSAEPFTDIPEMPDEEGLMVARGKRVYAVLNLYPYNPGHLM
MMAR_2089|M.marinum_M KRE--DSARS--QPFTEIPRLSDEEGLVVARGELVYAVLNLYPYNPGHLM
MUL_3255|M.ulcerans_Agy99 KRE--DSARS--QPFTEIPRLSDEEGLVVARGELVYAVLNLYPYNPGHLM
Mb2645c|M.bovis_AF2122/97 KRDP-NSSASPAQPFTEIPQLSDEEGLVVARGKLVYAVLNLYPYNPGHLM
Rv2613c|M.tuberculosis_H37Rv KRDP-NSSASPAQPFTEIPQLSDEEGLVVARGKLVYAVLNLYPYNPGHLM
MLBr_00455|M.leprae_Br4923 N----HDNSTPAQPFTDIPQLSDEDGLVVARGELVYAVLNLYPYNPGHLM
MAV_3489|M.avium_104 KRGP-NSSGKSEQPFTDIPQLTDEDGLVVARGELVYAVLNLYPYNPGHLM
MAB_2897c|M.abscessus_ATCC_199 APSP-DS-----APFTEIPEMADEDGLVVARGEHVYAVLNLYPYNPGHLM
TH_1725|M.thermoresistible__bu RRDG-SGSARSEQPFTDIPAMTDEDGLVVARGELVYAVLNLYPYNPGHLM
. **::** :.**:**:****. ****************
Mvan_2559|M.vanbaalenii_PYR-1 VVPYRRVAELENLTEAESAELMAFTQKAIRVMKAVSRPHGFNVGLNLGTS
Mflv_3837|M.gilvum_PYR-GCK VVPYRRVAELENLTEDESAELMAFTQKAIRVMKTVSRPHGFNVGLNLGTS
MSMEG_2932|M.smegmatis_MC2_155 VVPYRRVSELEDLTEDESSELMAFTQKAIRVIKAVSRPHGFNVGLNLGSS
MMAR_2089|M.marinum_M VVPYRRVSELEDLTEPESGELMAFTQKAIRVIKNVSRPHGFNVGMNLGTS
MUL_3255|M.ulcerans_Agy99 VVPYRRVSELENLTEPESGELMAFTQKAIRVVKNVSRPHGFNVGMNLGTS
Mb2645c|M.bovis_AF2122/97 VVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSRPHGFNVGLNLGTS
Rv2613c|M.tuberculosis_H37Rv VVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSRPHGFNVGLNLGTS
MLBr_00455|M.leprae_Br4923 VVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSRPHGFNVGLNLGTS
MAV_3489|M.avium_104 VVPYRRVSELEDLTDAESAELMSFIQKAIRVIKNVSRPHGFNVGLNLGTS
MAB_2897c|M.abscessus_ATCC_199 VVPYRQVAELEDLTEGESRELMAFTQKAIRVIKKVSRPHGFNVGLNLGSA
TH_1725|M.thermoresistible__bu VVPYRRVAELENLTVEETAELMAFTQKAIRVIKAVSRPHGFNVGLNLGAS
*****:*:***:** *: ***:* ******:* **********:***::
Mvan_2559|M.vanbaalenii_PYR-1 AGGSLSEHLHMHVVPRWGGDANFITVIGDSKVIPQLLRDTRLLLATEWDN
Mflv_3837|M.gilvum_PYR-GCK AGGSLSEHLHMHVVPRWGGDANFITVIGDSKVIPQLLRDTRLLLATEWEN
MSMEG_2932|M.smegmatis_MC2_155 AGGSLAEHLHMHVVPRWGGDANFITIIGGSKVIPQLLKETRQLLATEWVR
MMAR_2089|M.marinum_M AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
MUL_3255|M.ulcerans_Agy99 AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
Mb2645c|M.bovis_AF2122/97 AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
Rv2613c|M.tuberculosis_H37Rv AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
MLBr_00455|M.leprae_Br4923 AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRQLLATEWTK
MAV_3489|M.avium_104 AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRETRQLLATEWAK
MAB_2897c|M.abscessus_ATCC_199 AGGSLSEHLHQHVVPRWGGDANFITIIGDSKVLPQLLRDTRTLLATAWEQ
TH_1725|M.thermoresistible__bu AGGSLADHLHLHVVPRWSGDANFITIIGGSKVVPQLLRETRRLLAAEWAR
*****::*** ******.*******:**.***:****::** ***: * .
Mvan_2559|M.vanbaalenii_PYR-1 HK----------------
Mflv_3837|M.gilvum_PYR-GCK QK----------------
MSMEG_2932|M.smegmatis_MC2_155 QDQLAAGTDGKDGKAPTS
MMAR_2089|M.marinum_M QS----------------
MUL_3255|M.ulcerans_Agy99 QS----------------
Mb2645c|M.bovis_AF2122/97 QP----------------
Rv2613c|M.tuberculosis_H37Rv QP----------------
MLBr_00455|M.leprae_Br4923 QFMSRSGDDAERSL----
MAV_3489|M.avium_104 QS----------------
MAB_2897c|M.abscessus_ATCC_199 LP----------------
TH_1725|M.thermoresistible__bu QSEQQ-------------