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M. smegmatis MC2 155 MSMEG_2932 (-)

annotation: HIT family protein hydrolase
coordinates: 2995226 - 2995843
length: 205

VTDPDERQIVDRGVGDPDHLQRLWTPHRMSYIAEAPMKKRGEGGSAGSAEPFTDIPEMPDEEGLMVARGK
RVYAVLNLYPYNPGHLMVVPYRRVSELEDLTEDESSELMAFTQKAIRVIKAVSRPHGFNVGLNLGSSAGG
SLAEHLHMHVVPRWGGDANFITIIGGSKVIPQLLKETRQLLATEWVRQDQLAAGTDGKDGKAPTS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2932--100% (205)HIT family protein hydrolase
M. smegmatis MC2 155MSMEG_5028-6e-0726.26% (99) HIT family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2645c-7e-8480.43% (184) hypothetical protein Mb2645c
M. gilvum PYR-GCKMflv_3837-7e-8480.11% (186) histidine triad (HIT) protein
M. tuberculosis H37RvRv2613c-7e-8480.43% (184) hypothetical protein Rv2613c
M. leprae Br4923MLBr_00455-3e-8273.47% (196) hypothetical protein MLBr_00455
M. abscessus ATCC 19977MAB_2897c-4e-8079.46% (185) hypothetical protein MAB_2897c
M. marinum MMMAR_2089-2e-8378.38% (185) hypothetical protein MMAR_2089
M. avium 104MAV_3489-3e-8678.87% (194) diadenosine tetraphosphate
M. thermoresistible (build 8)TH_1725-7e-8781.18% (186) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_3255-8e-8377.30% (185) hypothetical protein MUL_3255
M. vanbaalenii PYR-1Mvan_2559-3e-8280.33% (183) histidine triad (HIT) protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3837|M.gilvum_PYR-GCK          -----MD-------PED---TIVDRGVGDPDRLQRLWTPHRMTYIADAVK
Mvan_2559|M.vanbaalenii_PYR-1       -----MD-------PED---TIVDRGVGDPDRLQRLWTPHRMTYIVDAVK
MSMEG_2932|M.smegmatis_MC2_155      ----MTD-------PDER--QIVDRGVGDPDHLQRLWTPHRMSYIAEAPM
MMAR_2089|M.marinum_M               ----MTNEESAQ--PQDS--TILDRGVGERDHLERLWTPYRMNYLAEAPL
MUL_3255|M.ulcerans_Agy99           ----MTNEESAQ--PQDS--TILDRGVGERDHLERLWTPYRMNYLAEAPL
Mb2645c|M.bovis_AF2122/97           ----MSDEDRTDRATEDH--TIFDRGVGQRDQLQRLWTPYRMNYLAEAPV
Rv2613c|M.tuberculosis_H37Rv        ----MSDEDRTDRATEDH--TIFDRGVGQRDQLQRLWTPYRMNYLAEAPV
MLBr_00455|M.leprae_Br4923          ----MSEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPV
MAV_3489|M.avium_104                ----MSDPEQAEQDAER---TILDRGVGEQDHLQRLWTPYRMTYLAEAPM
MAB_2897c|M.abscessus_ATCC_199      ----MTD--------QDS--TIIDRGVGDPDHLQRLWSPHRMSYIAEAVK
TH_1725|M.thermoresistible__bu      VTAGHNNEGRDRELGDER--TIVDQGPGEPDHLQRLWTPHRMSYIAEAPK
                                          :        :     *.* * *: *:*:***:*:**.*:.:*  

Mflv_3837|M.gilvum_PYR-GCK          -----GGSAASSEPFSDIPNMSDEDGLVVARGDLVYAVLNLYPYNPGHLM
Mvan_2559|M.vanbaalenii_PYR-1       -----PGSASSSEPFTDIPNMSDEDGLVVARGELVYAVLNLYPYNPGHLM
MSMEG_2932|M.smegmatis_MC2_155      KKRGEGGSAGSAEPFTDIPEMPDEEGLMVARGKRVYAVLNLYPYNPGHLM
MMAR_2089|M.marinum_M               KRE--DSARS--QPFTEIPRLSDEEGLVVARGELVYAVLNLYPYNPGHLM
MUL_3255|M.ulcerans_Agy99           KRE--DSARS--QPFTEIPRLSDEEGLVVARGELVYAVLNLYPYNPGHLM
Mb2645c|M.bovis_AF2122/97           KRDP-NSSASPAQPFTEIPQLSDEEGLVVARGKLVYAVLNLYPYNPGHLM
Rv2613c|M.tuberculosis_H37Rv        KRDP-NSSASPAQPFTEIPQLSDEEGLVVARGKLVYAVLNLYPYNPGHLM
MLBr_00455|M.leprae_Br4923          N----HDNSTPAQPFTDIPQLSDEDGLVVARGELVYAVLNLYPYNPGHLM
MAV_3489|M.avium_104                KRGP-NSSGKSEQPFTDIPQLTDEDGLVVARGELVYAVLNLYPYNPGHLM
MAB_2897c|M.abscessus_ATCC_199      APSP-DS-----APFTEIPEMADEDGLVVARGEHVYAVLNLYPYNPGHLM
TH_1725|M.thermoresistible__bu      RRDG-SGSARSEQPFTDIPAMTDEDGLVVARGELVYAVLNLYPYNPGHLM
                                          .      **::** :.**:**:****. ****************

Mflv_3837|M.gilvum_PYR-GCK          VVPYRRVAELENLTEDESAELMAFTQKAIRVMKTVSRPHGFNVGLNLGTS
Mvan_2559|M.vanbaalenii_PYR-1       VVPYRRVAELENLTEAESAELMAFTQKAIRVMKAVSRPHGFNVGLNLGTS
MSMEG_2932|M.smegmatis_MC2_155      VVPYRRVSELEDLTEDESSELMAFTQKAIRVIKAVSRPHGFNVGLNLGSS
MMAR_2089|M.marinum_M               VVPYRRVSELEDLTEPESGELMAFTQKAIRVIKNVSRPHGFNVGMNLGTS
MUL_3255|M.ulcerans_Agy99           VVPYRRVSELENLTEPESGELMAFTQKAIRVVKNVSRPHGFNVGMNLGTS
Mb2645c|M.bovis_AF2122/97           VVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSRPHGFNVGLNLGTS
Rv2613c|M.tuberculosis_H37Rv        VVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSRPHGFNVGLNLGTS
MLBr_00455|M.leprae_Br4923          VVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSRPHGFNVGLNLGTS
MAV_3489|M.avium_104                VVPYRRVSELEDLTDAESAELMSFIQKAIRVIKNVSRPHGFNVGLNLGTS
MAB_2897c|M.abscessus_ATCC_199      VVPYRQVAELEDLTEGESRELMAFTQKAIRVIKKVSRPHGFNVGLNLGSA
TH_1725|M.thermoresistible__bu      VVPYRRVAELENLTVEETAELMAFTQKAIRVIKAVSRPHGFNVGLNLGAS
                                    *****:*:***:**  *: ***:* ******:* **********:***::

Mflv_3837|M.gilvum_PYR-GCK          AGGSLSEHLHMHVVPRWGGDANFITVIGDSKVIPQLLRDTRLLLATEWEN
Mvan_2559|M.vanbaalenii_PYR-1       AGGSLSEHLHMHVVPRWGGDANFITVIGDSKVIPQLLRDTRLLLATEWDN
MSMEG_2932|M.smegmatis_MC2_155      AGGSLAEHLHMHVVPRWGGDANFITIIGGSKVIPQLLKETRQLLATEWVR
MMAR_2089|M.marinum_M               AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
MUL_3255|M.ulcerans_Agy99           AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
Mb2645c|M.bovis_AF2122/97           AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
Rv2613c|M.tuberculosis_H37Rv        AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRRLLATEWAR
MLBr_00455|M.leprae_Br4923          AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRDTRQLLATEWTK
MAV_3489|M.avium_104                AGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLRETRQLLATEWAK
MAB_2897c|M.abscessus_ATCC_199      AGGSLSEHLHQHVVPRWGGDANFITIIGDSKVLPQLLRDTRTLLATAWEQ
TH_1725|M.thermoresistible__bu      AGGSLADHLHLHVVPRWSGDANFITIIGGSKVVPQLLRETRRLLAAEWAR
                                    *****::*** ******.*******:**.***:****::** ***: * .

Mflv_3837|M.gilvum_PYR-GCK          QK----------------
Mvan_2559|M.vanbaalenii_PYR-1       HK----------------
MSMEG_2932|M.smegmatis_MC2_155      QDQLAAGTDGKDGKAPTS
MMAR_2089|M.marinum_M               QS----------------
MUL_3255|M.ulcerans_Agy99           QS----------------
Mb2645c|M.bovis_AF2122/97           QP----------------
Rv2613c|M.tuberculosis_H37Rv        QP----------------
MLBr_00455|M.leprae_Br4923          QFMSRSGDDAERSL----
MAV_3489|M.avium_104                QS----------------
MAB_2897c|M.abscessus_ATCC_199      LP----------------
TH_1725|M.thermoresistible__bu      QSEQQ-------------