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TTTEPGESQEAAHQGPDPAQETTSAPAPSPKPSAAVKPRPGPARPGPRPAVPAAAPVVGTAPTSDPHRFG RVDPDGTVWLITSSGERTIGSWQAGDAEAAYAHFGRRFDDLHTEVVLLETRLASGSGDARKIRSAAATLA ETLPEAHVLGDVDSLAARLAAIVEHAESATQEEKAKREEHRAAQTARKEALAAEAEDIAANSTQWKAAGD RLRAILDEWKTITGLDRKVDDALWKRYSAARETFNRRRGSHFADLDRERAGARQAKESLCQRAEELCDST EWGPTSATFRDLLTEWKAVGRAAKDVDDALWQRFKSAQDKFFSARNAATAERDAEFRANAQAKEALLAEA ERIDASDLDAARAALRAIGDKWDAIGKVPRERAPELERRMRAVEKKIRDAPTGGVDPEAKARAEQFRARA EQFERQAEKAAAAGRTKDAEQARASAEQWRQWAEAAADSLSRKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2431 | - | - | 100% (465) | hypothetical protein Mvan_2431 |
| M. vanbaalenii PYR-1 | Mvan_4435 | - | 2e-05 | 24.59% (366) | hypothetical protein Mvan_4435 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2750 | - | 0.0 | 70.98% (448) | hypothetical protein Mb2750 |
| M. gilvum PYR-GCK | Mflv_3965 | - | 0.0 | 84.71% (471) | hypothetical protein Mflv_3965 |
| M. tuberculosis H37Rv | Rv2731 | - | 0.0 | 70.98% (448) | hypothetical protein Rv2731 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3046 | - | 1e-171 | 71.46% (431) | hypothetical protein MAB_3046 |
| M. marinum M | MMAR_1981 | - | 0.0 | 74.55% (444) | hypothetical protein MMAR_1981 |
| M. avium 104 | MAV_3624 | - | 0.0 | 76.27% (413) | hypothetical protein MAV_3624 |
| M. smegmatis MC2 155 | MSMEG_2731 | - | 0.0 | 78.32% (452) | ATPase involved in DNA repair |
| M. thermoresistible (build 8) | TH_1782 | - | 0.0 | 78.19% (408) | CONSERVED HYPOTHETICAL ALANINE AND ARGININE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_3376 | - | 0.0 | 74.32% (444) | hypothetical protein MUL_3376 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2750|M.bovis_AF2122/97 ----------------MTADEPRSDDSSGSAPQPAATPVPRPGPRPGPRP
Rv2731|M.tuberculosis_H37Rv ----------------MTADEPRSDDSSGSAPQPAATPVPRPGPRPGPRP
MMAR_1981|M.marinum_M -----------------MADEPRGNDLHPTVSGPGPRPGPRPGPRPGPRP
MUL_3376|M.ulcerans_Agy99 ----------------MTADEPRGNDLHPTVSGPGPRPGPRPGPRPGPRP
MAV_3624|M.avium_104 ----------------MSAG------------------------------
Mvan_2431|M.vanbaalenii_PYR-1 MTTTEPGESQEAAHQ---GPDPAQETTSAPAPSPKPSAAVKPRPGPA-RP
Mflv_3965|M.gilvum_PYR-GCK MTITESGGSQDAGQQTAEADNTAPAPEAPPSPRPKPSAAR-PKPGPAPRP
MSMEG_2731|M.smegmatis_MC2_155 -MRGPPRGVRGADMT------TSEPGGATPKPTPR------PTPHPTPRP
TH_1782|M.thermoresistible__bu --------------------------------------------------
MAB_3046|M.abscessus_ATCC_1997 ----------------------MSDQTQPELSTQQERVTPVPRPGPKPHP
Mb2750|M.bovis_AF2122/97 VPRPTSY---PVGAHPP-SDPHRFGRIDDDGTVWLVSASGERIVGSWQAG
Rv2731|M.tuberculosis_H37Rv VPRPTSY---PVGAHPP-SDPHRFGRIDDDGTVWLVSASGERIVGSWQAG
MMAR_1981|M.marinum_M SPRPVAH---PVVVSAP-SDPHRFGRVDDDGTVWLITTAGERIVGSWQAG
MUL_3376|M.ulcerans_Agy99 SPRPVAH---PVVVSAP-SDPHRFGRVDDDGTVWLITTAGERIVGSWQAG
MAV_3624|M.avium_104 --RPAAH---PVVVPPPPSDPHRFGRVDDDGTVWLISAAGERVVGSWQAG
Mvan_2431|M.vanbaalenii_PYR-1 GPRPAVPAAAPVVGTAPTSDPHRFGRVDPDGTVWLITSSGERTIGSWQAG
Mflv_3965|M.gilvum_PYR-GCK VPRPSTPAAAPVVNTVPSSDPHRFGRVDPDGTVWLITASGERTIGSWQAG
MSMEG_2731|M.smegmatis_MC2_155 VPRPSR--VAPVVAAAPSSDPHRFGRVDPDGTVWLITGSGERVIGAWQAG
TH_1782|M.thermoresistible__bu ------------VAAPPASDPHKFGRVDADGTVWLITSEGERVIGSWQAG
MAB_3046|M.abscessus_ATCC_1997 MPRRPAA----PAPAAHHVDPHKFGRVDDDGTVWLITSAGERQIGSWQAG
***:***:* ******:: *** :*:****
Mb2750|M.bovis_AF2122/97 DPEAAFAHFGRRFDDLSTEIMLMDERLASGTGDARKIKAHAIALAETLPT
Rv2731|M.tuberculosis_H37Rv DPEAAFAHFGRRFDDLSTEIMLMDERLASGTGDARKIKAHAIALAETLPT
MMAR_1981|M.marinum_M DAEAAFAHFGRRFDDLNTEITLMEERLAAGTGDARKIRANAAALAETLPT
MUL_3376|M.ulcerans_Agy99 DAEAAFAHFGRRFDDLNTEITLMEERLAAGTGDARKIRANAAALAETLPI
MAV_3624|M.avium_104 DREAAFAHFGRRFDDLATEVTLMEERLASGTGDARKIKAHASELAESLPT
Mvan_2431|M.vanbaalenii_PYR-1 DAEAAYAHFGRRFDDLHTEVVLLETRLASGSGDARKIRSAAATLAETLPE
Mflv_3965|M.gilvum_PYR-GCK DAEAAYAHFGRRFDDLQTEVVLLETRLASGAGDARKIKSAASTLADTLPE
MSMEG_2731|M.smegmatis_MC2_155 DTESAFAHFGRRYDDLHTEVALLERRLATGTGDARKIKSAAAALAESLPT
TH_1782|M.thermoresistible__bu DAEAAYAHFGRRYDDLHTEVALLERRLASRTGDARKIRAAAAALAESLPT
MAB_3046|M.abscessus_ATCC_1997 DADAAYAHFGRRFEDLETEVQLLELRLGSGSGDARKIKTAAEHLAETLPA
* ::*:******::** **: *:: **.: :******:: * **::**
Mb2750|M.bovis_AF2122/97 ACVLGDVDALADRLTSIRDRAEVIAAADRSRREEHRAAQTARKEALAAEA
Rv2731|M.tuberculosis_H37Rv ACVLGDVDALADRLTSIRDRAEVIAAADRSRREEHRAAQTARKEALAAEA
MMAR_1981|M.marinum_M ASVLGDLDALATRLASLCEQADSMAVADRTKRDEHRAAQTSRKEALAAEA
MUL_3376|M.ulcerans_Agy99 ASVLGDLDALATRLASLCEQADSMAVADRTKRDEHRAAQTSRKEALAAEA
MAV_3624|M.avium_104 ATVLGDIDALAARLASIAEQAEAAVAAERSRREEHRAAQTARKEALAAEA
Mvan_2431|M.vanbaalenii_PYR-1 AHVLGDVDSLAARLAAIVEHAESATQEEKAKREEHRAAQTARKEALAAEA
Mflv_3965|M.gilvum_PYR-GCK AHVLGDVDALAARLAAIVEQAEGATQQEKARREELRAANTARKEALAAEA
MSMEG_2731|M.smegmatis_MC2_155 ASVLGDVDALSARLSSILEQADEAAQNERAQRDEYRAAQTARKEALAAEA
TH_1782|M.thermoresistible__bu AAVLGDVDALAVRLSAVLEQAEEAANAEKARREEFRRAQIARKEALAAEA
MAB_3046|M.abscessus_ATCC_1997 AAVLGDVDSLSARLSALVESADAQAAAARAQRDEARSASISRKEELAAEA
* ****:*:*: **::: : *: . :::*:* * *. :*** *****
Mb2750|M.bovis_AF2122/97 EELAANATQWKVAGDRLRAILDEWKTISGVDRKVDDALWKRYSTARDTFN
Rv2731|M.tuberculosis_H37Rv EELAANATQWKVAGDRLRAILDEWKTISGVDRKVDDALWKRYSTARDTFN
MMAR_1981|M.marinum_M EELAANSTQWKAAGDRLRAILDEWKTISGLDRKVDDALWKRYSAARDTFN
MUL_3376|M.ulcerans_Agy99 EELAANSTQWKAAGDRLRAILDEWKTISGLDRKVDDALWKRYSAARDTFN
MAV_3624|M.avium_104 EELAANSTQWKAAGDRLRAILDEWKTITGLDRRVDDALWKRYSAAREAFN
Mvan_2431|M.vanbaalenii_PYR-1 EDIAANSTQWKAAGDRLRAILDEWKTITGLDRKVDDALWKRYSAARETFN
Mflv_3965|M.gilvum_PYR-GCK EDLAANATQWKAAGDRMRAILDEWKTITGLDRKVDDALWKRYSAARETFN
MSMEG_2731|M.smegmatis_MC2_155 EDIAANSTQWKAAGDRLREILDEWRTITGLERKADDALWKRYSAARETFN
TH_1782|M.thermoresistible__bu EDIAANSMQWKAAGDRLRAILDEWRTITGVDRKTDDALWKRYSAAREMFN
MAB_3046|M.abscessus_ATCC_1997 EELAANSTQWKAAGDRIRAILDEWKSIHGVDRKTDDALWKRYSTARETFN
*::***: ***.****:* *****::* *::*:.*********:**: **
Mb2750|M.bovis_AF2122/97 RRRGSHFAELDRERSGVRQSKERLCERAEELSESTDWTATSAEFRKLLAD
Rv2731|M.tuberculosis_H37Rv RRRGSHFAELDRERSGVRQSKERLCERAEELSESTDWTATSAEFRKLLAD
MMAR_1981|M.marinum_M RRRGSHFAELDRERSGVKQSKERLCERAEELSDSTDWAPTSAEFRKLLAE
MUL_3376|M.ulcerans_Agy99 RRRGSHFAELDRERSGVKQSKERLCERAEELSDSTDWAPTSAEFRKLLAE
MAV_3624|M.avium_104 RRRGAHFAELDRERSSIRQAKERLCERAEELSGSTDWTATSAEFRKLLAE
Mvan_2431|M.vanbaalenii_PYR-1 RRRGSHFADLDRERAGARQAKESLCQRAEELCDSTEWGPTSATFRDLLTE
Mflv_3965|M.gilvum_PYR-GCK RRRGSHFAELDRERAGAKQAKEALCERAEALCDSTDWGPTSGLFRDLLTE
MSMEG_2731|M.smegmatis_MC2_155 RRRGSHFAELDRSRVSARQAKEELCERAEALADSTDWGATSAAFRDLLAE
TH_1782|M.thermoresistible__bu RRRGSHFAELDRERAQARRAKEALCERAEELADSTDWGPTSAAFRELLAE
MAB_3046|M.abscessus_ATCC_1997 RRRGAHFAELDRERAGAREKKEELCKRAEALSDSTDWGATSAAFRNLLND
****:***:***.* :. ** **:*** *. **:* .**. **.** :
Mb2750|M.bovis_AF2122/97 WKAAGRASKDVDDALWRRFKAAQDSFFTARNAATAEKEAELRANADAKEA
Rv2731|M.tuberculosis_H37Rv WKAAGRASKDVDDALWRRFKAAQDSFFTARNAATAEKEAELRANADAKEA
MMAR_1981|M.marinum_M WKAAGRASKDVDDALWRRFKAAQDAFFTARNAATAERDAEFRANATAKEA
MUL_3376|M.ulcerans_Agy99 WKAAGRASKDVDDALWRRFKAAQDAFFTARNAATAERDAEFRANATAKEA
MAV_3624|M.avium_104 WKAAGRAAREVDDALWRRFKQAQDVFFTARNAATAEKDAELRANAAAKEA
Mvan_2431|M.vanbaalenii_PYR-1 WKAVGRAAKDVDDALWQRFKSAQDKFFSARNAATAERDAEFRANAQAKEA
Mflv_3965|M.gilvum_PYR-GCK WKNAGRASKDVDDALWQRFKAAQDRFFAARNAATAERDAEFRANAEAKEA
MSMEG_2731|M.smegmatis_MC2_155 WKAAGRAAKDVDDALWQRFKAAQDTFFSARNAAHAERDAEFKANAAAKEA
TH_1782|M.thermoresistible__bu WKATGRAAKDVDDALWQRFKAAQDKFFTARNAVHAERDAELRANAEAKEK
MAB_3046|M.abscessus_ATCC_1997 WKAAGRAPRETDDNLWHRFKAAQDKFFAARNAESASRDAEFVANAEAKRA
** .***.::.** **:*** *** **:**** *.::**: *** **.
Mb2750|M.bovis_AF2122/97 LLAEAERLD-TTNHEAARAALRSIAEKWDAIGKVSRERAAELERRLRAVE
Rv2731|M.tuberculosis_H37Rv LLAEAERLD-TTNHEAARAALRSIAEKWDAIGKVSRERAAELERRLRAVE
MMAR_1981|M.marinum_M LLVEAEKLD-TTNRDAARAALRTITDKWDAIGRVPRERTAELERRLRAVE
MUL_3376|M.ulcerans_Agy99 LLVEAEKLD-TTNRDAARAALRTITDKWDAIGRVPRERTAELERRLRAVE
MAV_3624|M.avium_104 LLAEAEKLD-TGNHDAARAALRAIAEKWDAIGKVPRERSAELERRLRAVE
Mvan_2431|M.vanbaalenii_PYR-1 LLAEAERID-ASDLDAARAALRAIGDKWDAIGKVPRERAPELERRMRAVE
Mflv_3965|M.gilvum_PYR-GCK LLAEAERID-ASDVDAARAALRAIGDKWDAIGKVPRERAADLERRMRAVE
MSMEG_2731|M.smegmatis_MC2_155 LLAEAEKID-LSDNEAARAALRVIGEKWDAIGKVPRERAAELERRLRAIE
TH_1782|M.thermoresistible__bu LLEQAEKID-TGDVDAARAALRAIVEKWDAIGKVPRDRTAELERRLRAVE
MAB_3046|M.abscessus_ATCC_1997 LLVEAEKIDPEADVDAARAALRAIGDKWDAIGKVPREQQADLERRLRAVE
** :**::* : :******* * :******:*.*:: .:****:**:*
Mb2750|M.bovis_AF2122/97 KKVREAGEADWSDPQARARAEQFRARAEQFEHQAEKAAAAGRTKEADEAK
Rv2731|M.tuberculosis_H37Rv KKVREAGEADWSDPQARARAEQFRARAEQFEHQAEKAAAAGRTKEADEAK
MMAR_1981|M.marinum_M KKVREAGESNWSDPQAQARAEQFQARVEQFEQQAAKAAAAGKTKEAEQAK
MUL_3376|M.ulcerans_Agy99 KKVREAGESNWSDPQAQARAEQFQARVEQFEQQAAKAAAAGKTKETEQAK
MAV_3624|M.avium_104 KKVREAGDAGWSDPQAQARAEQFQARAEQYEQQARKAAAAGRTKEAEEAR
Mvan_2431|M.vanbaalenii_PYR-1 KKIRDAPTGG-VDPEAKARAEQFRARAEQFERQAEKAAAAGRTKDAEQAR
Mflv_3965|M.gilvum_PYR-GCK KKIRDAPTGG-VDPEAQARADQFRERAEQFERQAEKAAAAGKTKDAEKAR
MSMEG_2731|M.smegmatis_MC2_155 KKIREAPTGG-VDPEAKARADQFRARAEQFERQAEKAEAAGRTKDAEEAR
TH_1782|M.thermoresistible__bu KRVRDAASSGWTDPEAQARADQFRIRAEQYEQQAAKAEAAGRTKDAEEAR
MAB_3046|M.abscessus_ATCC_1997 KKVREAGESGWGDPEAEARAEQFRDRARQFEEQAAKAEAAGKTKDAEKAR
*::*:* .. **:*.***:**: *..*:*.** ** ***:**::::*:
Mb2750|M.bovis_AF2122/97 ANAEQWRQWAEAAADALTRRP-
Rv2731|M.tuberculosis_H37Rv ANAEQWRQWAEAAADALTRRP-
MMAR_1981|M.marinum_M ANAEQWRQWAAAAADALTRKT-
MUL_3376|M.ulcerans_Agy99 ANAEQWRQWAAAAADALTRKT-
MAV_3624|M.avium_104 ANAEQWRQWAQAAVEALSRKP-
Mvan_2431|M.vanbaalenii_PYR-1 ASAEQWRQWAEAAADSLSRKR-
Mflv_3965|M.gilvum_PYR-GCK ANAEQWRQWADAAADSLSRKR-
MSMEG_2731|M.smegmatis_MC2_155 ASAAQWRQWAEAAAESLEKRR-
TH_1782|M.thermoresistible__bu ANAAQWRQWAEAAAQALEKRR-
MAB_3046|M.abscessus_ATCC_1997 ASAQQWQEWADAAVAAVKSRSR
*.* **::** **. :: :