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AGSVLFDVPGPRARLRNHAVSAVTVVVVLLVAWVVYARLDSRGQLTAAKWEPFLTADLWRTYVLPGIEGT LTAAAVSIVLALALGFVLGVGRLSTHTAIRWASSVFVEFFRAVPVLIMMIFAYFLYAFYDVFPSKHLALA GVITGLTLYNGAVIAEIVRAGVHALPRGQTEAASALGLTWGQTMRSILLPQAITSMLPVLISQLVVVLKD TALGYQITFVEMVRQGTVIGSAYGNYIPALIVIALLMIALNFTLSWLATRLERRMRRSRKGPAPMEAEPL DLQGDRSRGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2425 | - | - | 100% (291) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_4703 | - | 3e-28 | 35.47% (203) | polar amino acid ABC transporter, inner membrane subunit |
| M. vanbaalenii PYR-1 | Mvan_6047 | - | 1e-22 | 28.75% (240) | polar amino acid ABC transporter, inner membrane subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0953 | pstA1 | 7e-06 | 24.55% (224) | phosphate ABC transporter transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3971 | - | 1e-149 | 91.07% (291) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0930 | pstA1 | 7e-06 | 24.55% (224) | phosphate ABC transporter transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3053 | - | 1e-86 | 57.09% (268) | putative glutamate ABC transporter, permease |
| M. marinum M | MMAR_0061 | glnQ | 3e-23 | 28.38% (229) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 2e-22 | 28.94% (235) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_2725 | - | 1e-118 | 75.53% (282) | glutamate transporter permease protein GluD |
| M. thermoresistible (build 8) | TH_3737 | - | 1e-102 | 65.60% (282) | PUTATIVE glutamate transporter permease protein GluD |
| M. ulcerans Agy99 | MUL_4375 | proW | 2e-06 | 26.61% (233) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2425|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3971|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2725|M.smegmatis_MC2_155 --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_3053|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
Mb0953|M.bovis_AF2122/97 --------------------------------------------------
Rv0930|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2425|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3971|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2725|M.smegmatis_MC2_155 --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_3053|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGTLSDAP
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTLSGAP
Mb0953|M.bovis_AF2122/97 --------------------------------------------------
Rv0930|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2425|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3971|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2725|M.smegmatis_MC2_155 --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_3053|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0061|M.marinum_M PNTCINSTGQFTGFDNELLRAIAAKLGLQVRFVGTDFSGLLAQVAARRFD
MAV_0059|M.avium_104 PNVCITPTGQYSGFDNQLLRAIAGKLGLQVRFVGTDFAGLLAQVASRRFD
Mb0953|M.bovis_AF2122/97 --------------------------------------------------
Rv0930|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2425|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3971|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2725|M.smegmatis_MC2_155 --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_3053|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0061|M.marinum_M VGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSDLAPGQRIG
MAV_0059|M.avium_104 VGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTDLAAGQRIG
Mb0953|M.bovis_AF2122/97 --------------------------------------------------
Rv0930|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2425|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3971|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2725|M.smegmatis_MC2_155 --------------------------------------------------
TH_3737|M.thermoresistible__bu --------------------------------------------------
MAB_3053|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0061|M.marinum_M VVQGTVEESYVVNSLHLQPVKYPDFATVYGNLKTHQIDAWVAPGNQAEAA
MAV_0059|M.avium_104 VVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTRQIDAWVAPAGQAATT
Mb0953|M.bovis_AF2122/97 --------------------------------------------------
Rv0930|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4375|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2425|M.vanbaalenii_PYR-1 --------------MAG-SVLFDVPGPRARLRNHAVSAVTVVVVLLVAWV
Mflv_3971|M.gilvum_PYR-GCK --------------MAG-SVLFDAPGPRARVRNRVITAVTVVAVLAVAWV
MSMEG_2725|M.smegmatis_MC2_155 --------------MTGASVLFDAPGPRARVRNGILTAVSAVIGTLVVAF
TH_3737|M.thermoresistible__bu --------------MSTTSVLFDAPGPRARRRNRIATAVTVVVVAAVFGV
MAB_3053|M.abscessus_ATCC_1997 --------------MTGATVMYDAPGPKGRALNRIIAVVFTALVGVVAAW
MMAR_0061|M.marinum_M IRPGDPAVLVANTFGAGDFVAYVVARDNRPLLDALNSGLDAVIADGTWSQ
MAV_0059|M.avium_104 IQPGDPAVVVANTISPGNFVAYAVAKDNKPLVDALNSGLDAVIADGTWSN
Mb0953|M.bovis_AF2122/97 ---MSPSTSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIP
Rv0930|M.tuberculosis_H37Rv ---MSPSMSIEALDQPVKPVVFRPLTLRRRIKNSVATTFFFTSFVVALIP
MUL_4375|M.ulcerans_Agy99 ----------------------------------MHYLMTHLGTAWALTM
. .
Mvan_2425|M.vanbaalenii_PYR-1 VYARLD--------------------------------------SRGQLT
Mflv_3971|M.gilvum_PYR-GCK VYSRLD--------------------------------------ERGQLT
MSMEG_2725|M.smegmatis_MC2_155 VLWQLW--------------------------------------TKNQLT
TH_3737|M.thermoresistible__bu VLHRLA--------------------------------------AQGQLA
MAB_3053|M.abscessus_ATCC_1997 VIWTLV--------------------------------------ANEQLT
MMAR_0061|M.marinum_M LYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAAHRHKPVGPAAPKSAL
MAV_0059|M.avium_104 LYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQHHKAVGPAAPKSTL
Mb0953|M.bovis_AF2122/97 LVWLLWVVIAR---------------------------------GWFAVT
Rv0930|M.tuberculosis_H37Rv LVWLLWVVIAR---------------------------------GWFAVT
MUL_4375|M.ulcerans_Agy99 VHLRLS--------------------------------------------
:
Mvan_2425|M.vanbaalenii_PYR-1 AAKWEPFLTADLWR----TYVLPGIEGTLTAAAVSIVLALALGFVLGVGR
Mflv_3971|M.gilvum_PYR-GCK AEKWEPFLTGDLWR----TYVLPGIEGTLTAAAVSIVLALILGFVLGVGR
MSMEG_2725|M.smegmatis_MC2_155 SEKWEPFLTANLWK----TYVLPGVQGTLTAAAVSIVLALALGLALGVGR
TH_3737|M.thermoresistible__bu ADKWTPFLNANVWK----TYLLPGLRGTLVAAGISIVLAMILGVLFGVGR
MAB_3053|M.abscessus_ATCC_1997 TEKWSPFLRLNTWT----TYILPGLLGTVTAAALSIVFALALGAVLGIGR
MMAR_0061|M.marinum_M TQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLSASIIGLALGMALAIAG
MAV_0059|M.avium_104 AQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSASVIGLVLGMVLAVAG
Mb0953|M.bovis_AF2122/97 RSGWWTHSLRGVLPEQFAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYL
Rv0930|M.tuberculosis_H37Rv RSGWWTHSLRGVLPEQFAGGVYHALYGTLVQAGVAAVLAVPLGLMTAVYL
MUL_4375|M.ulcerans_Agy99 ----------------------------LIPVLIGTAIAIPLGLFVQHAP
: . . :.: **
Mvan_2425|M.vanbaalenii_PYR-1 LSTHT-AIRWASSVFVEFFRAVPVLIMMIFAYFLYAFYDVFPSKHLALAG
Mflv_3971|M.gilvum_PYR-GCK LSTHT-PIRWVSSVLVEFFRAVPVLIMMIFAYFLYAFYDVFPSKYLALAG
MSMEG_2725|M.smegmatis_MC2_155 LAPIR-PIRWVCTVIVEFFRAVPVLIMMIFAYFFYAAYDVFPSKHLALAG
TH_3737|M.thermoresistible__bu LSPWR-VVRWPCAMLVEFFRAVPVLIMMIFAWQFYSLFNVVPARHSVLAG
MAB_3053|M.abscessus_ATCC_1997 LSEHR-AVRWICSALVEFFRAIPVLILMVFSYYLYGQQAVFPSEYLAFAA
MMAR_0061|M.marinum_M ISHQR-WLRWPARVYTDIFRGLPEVVIILIIGLGVGPIVGGLTNNNPYPL
MAV_0059|M.avium_104 ISHAR-WLRWPARVYTDVFRGLPEVVIILLIGLGIGPIVGGLTNNNPYPL
Mb0953|M.bovis_AF2122/97 VEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFAVAL
Rv0930|M.tuberculosis_H37Rv VEYGTGRMSRVTTFTVDVLAGVPSIVAALFVFSLWIATLGFQQSAFAVAL
MUL_4375|M.ulcerans_Agy99 T------LRRLTTATASVVFTIPSLALFVVLPLIIKMRILQEAN------
: .... :* : :.
Mvan_2425|M.vanbaalenii_PYR-1 VITGLTLYNGAVIAEIVRAGVHALPRGQTEAASALGLTWGQTMRSILLPQ
Mflv_3971|M.gilvum_PYR-GCK VITGLTLYNGAVIAEIVRAGVHALPRGQAEASSALGLTWGQTMRSILLPQ
MSMEG_2725|M.smegmatis_MC2_155 VITGLTLYNGSVIAEIVRAGVHSLPRGQSEAAASLGLSWWQTMRMIQLPQ
TH_3737|M.thermoresistible__bu VVTGLTLYNGAVIAEAIRTGVNNLPRGQAEAAYALGMRWRQTMWSIELPQ
MAB_3053|M.abscessus_ATCC_1997 VVTGLSLYNGSVIAEILRSGIQSLPKGQSEAAVALGMRKSQMMRLILLPQ
MMAR_0061|M.marinum_M GIAALGLMAGAYVGEILRSGIQSVDPGQLEASRALGFSYSAAMRLVVVPQ
MAV_0059|M.avium_104 GIAALGMMAAAYIGEILRSGIQSVDPGQLEASRALGFSYATAMRLVVVPQ
Mb0953|M.bovis_AF2122/97 ALVLLMLP---VVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPI
Rv0930|M.tuberculosis_H37Rv ALVLLMLP---VVVRAGEEMLRLVPDELREASYALGVPKWKTIVRIVAPI
MUL_4375|M.ulcerans_Agy99 VIIALSAYTTALLVRAVLEALDAVPAQVRDAAVAVGYSPIARMLKVELPL
: * : . : : :*: ::* : : *
Mvan_2425|M.vanbaalenii_PYR-1 AITSMLP-VLISQLVVVLKDTALGYQITFVEMVRQGTVIG---SAYGNYI
Mflv_3971|M.gilvum_PYR-GCK AVTSMLP-VLISQLVVVLKDTALGYQITFVEMVRQGTVIG---SAYGNYI
MSMEG_2725|M.smegmatis_MC2_155 AITAMLP-VLVSQLVVVLKDTAIGYQITFVEMVRQGTVIG---SSYGNYL
TH_3737|M.thermoresistible__bu AITSMLP-VLVSQMVVVLKDTALGYQISYLEVVRQGRIVG---TAFQNYI
MAB_3053|M.abscessus_ATCC_1997 SISAMLP-ALISQMVIALKDSALGYAFGYIEVVRSGIRSA---SYYGNYL
MMAR_0061|M.marinum_M GVRRVLP-ALVNQFIALLKASALVYFLGLIAQQRELFQVGRDLNAQTGNL
MAV_0059|M.avium_104 GVRRVLP-ALVNQFIALLKASALVYFLGLVADQRELFQVGRDLNAETGNL
Mb0953|M.bovis_AF2122/97 AMPGIVSGILLSIARVVGETAPVLVLVGYSHSINLDVFHG-----NMASL
Rv0930|M.tuberculosis_H37Rv AMPGIVSGILLSIARVVGETAPVLVLVGYSHSINLDVFHG-----NMASL
MUL_4375|M.ulcerans_Agy99 SIPVLVS-GLRVVVVTNIAMVSVGAVIGIGG-LGTWFTAGYLMDKSDQIV
.: ::. * .: . . :
Mvan_2425|M.vanbaalenii_PYR-1 PALIVIALLMIALNFTLSWLATRLERRMRRSRKGPAPMEAEPLDLQGDRS
Mflv_3971|M.gilvum_PYR-GCK PALIVIAVLMIALNFSLSWFATWLEKRMRRSRKGPAPMEAEPLELQGDRS
MSMEG_2725|M.smegmatis_MC2_155 PALIVIAVLMISVNFALSALATRIERRLRRSTRGPAPMHAEAVEQEGAPG
TH_3737|M.thermoresistible__bu PTLIVVAVLMIALNFALSALAGWIERRMRRSRRGPAPARAHAVEQDGVPG
MAB_3053|M.abscessus_ATCC_1997 PALVVVAVIMIIINFALSSLATRIERQLRQGR------TKKTIEKDLSQD
MMAR_0061|M.marinum_M SPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRRRLDPEDPPGVVSSTIGE
MAV_0059|M.avium_104 SPLVAAGACYLILTVPLTHLVNMIDARLRRGRAAVDPEEPAEMLT--FGQ
Mb0953|M.bovis_AF2122/97 PLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRR--
Rv0930|M.tuberculosis_H37Rv PLLIYTELTNPEHAGFLRVWGAALTLIIVVATINLAAAMIRFVATRRRRL
MUL_4375|M.ulcerans_Agy99 AGITVMFVLAILIDMVLN-VAGRLATPWERSSRGRRRFRSPIVGGAR---
. : * : . :
Mvan_2425|M.vanbaalenii_PYR-1 RGV-------
Mflv_3971|M.gilvum_PYR-GCK RGV-------
MSMEG_2725|M.smegmatis_MC2_155 ADVLTGQADK
TH_3737|M.thermoresistible__bu APVR------
MAB_3053|M.abscessus_ATCC_1997 FGE-------
MMAR_0061|M.marinum_M EMT-------
MAV_0059|M.avium_104 EIT-------
Mb0953|M.bovis_AF2122/97 ----------
Rv0930|M.tuberculosis_H37Rv PL--------
MUL_4375|M.ulcerans_Agy99 ----------