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VLNAPRQSSVRAGSALTLAVVTSPHDPGPWQRPDDSAGRPASASLVDPEDDLPSAHYGGDFETTAIPRYD SAKPAGQQPFALLNEPEPLPYVQPGTGLAPGSYGSTAAPTEVGVIDPDRRDDRRGTQDLGLLVLRVAVGV LLIGHGLQKVFGWWGGPGLDGFRDTLTEVGFRHADILTYVAAGGQIAAGVLLVIGLFTPIAAAGALGYLI TSVLAEATLAHEEARLSSFLTDGHEYQVVLVCAVAAIILVGPGRYGLDAGRGWARRPFVGSFAALLLGIG AGVAIWVLLNGTNPLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2120 | - | - | 100% (296) | DoxX family protein |
| M. vanbaalenii PYR-1 | Mvan_4592 | - | 8e-15 | 32.34% (167) | DoxX family protein |
| M. vanbaalenii PYR-1 | Mvan_4574 | - | 2e-14 | 28.80% (184) | DoxX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3030c | - | 7e-86 | 57.44% (289) | hypothetical protein Mb3030c |
| M. gilvum PYR-GCK | Mflv_4241 | - | 1e-143 | 85.86% (297) | DoxX family protein |
| M. tuberculosis H37Rv | Rv3005c | - | 7e-86 | 57.44% (289) | hypothetical protein Rv3005c |
| M. leprae Br4923 | MLBr_01698 | - | 2e-77 | 54.87% (277) | hypothetical protein MLBr_01698 |
| M. abscessus ATCC 19977 | MAB_3332c | - | 5e-78 | 53.62% (276) | hypothetical protein MAB_3332c |
| M. marinum M | MMAR_1707 | - | 2e-85 | 57.04% (291) | hypothetical protein MMAR_1707 |
| M. avium 104 | MAV_3854 | - | 2e-79 | 54.51% (288) | DoxX subfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_2370 | - | 1e-104 | 67.02% (285) | DoxX subfamily protein, putative |
| M. thermoresistible (build 8) | TH_4069 | - | 6e-86 | 58.72% (281) | PUTATIVE DoxX family protein |
| M. ulcerans Agy99 | MUL_1944 | - | 2e-84 | 56.36% (291) | hypothetical protein MUL_1944 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2120|M.vanbaalenii_PYR-1 MLNAPRQSSVRAGSALTLAVVTSPHDPGPWQRPDDS----AGRPASASLV
Mflv_4241|M.gilvum_PYR-GCK MLNAPSEFPARDRSALTLAVVTSPLDPRPWQRPDDS----AGRPASASLV
MSMEG_2370|M.smegmatis_MC2_155 -------------------MTSSSQDP--WQRPDNPGTGDSARPAGASLV
TH_4069|M.thermoresistible__bu -----------------------------------------VRPASASLV
MAB_3332c|M.abscessus_ATCC_199 -------------------MTGHSDDP-------------QVWRKPPELV
Mb3030c|M.bovis_AF2122/97 -------------------MTS-SNDSH-WQRPDDSPGPMPGRPVSASLV
Rv3005c|M.tuberculosis_H37Rv -------------------MTS-SNDSH-WQRPDDSPGPMPGRPVSASLV
MMAR_1707|M.marinum_M -------------------MTS-SNDSR-WQRPDDSPGPIPGRPVTASLV
MUL_1944|M.ulcerans_Agy99 -------------------MTS-SNDSR-WQRPDDSPGPIPGRPVTASLV
MLBr_01698|M.leprae_Br4923 -------------------MTGQSHDEH-WRRPGECPEPIPGRPASASLV
MAV_3854|M.avium_104 -------------------MTSQPNDAH-WQRPGESPEPTPGRPASARLV
. **
Mvan_2120|M.vanbaalenii_PYR-1 DPEDDLPSAHYGGDF-----ETTAIPRYDSAKPAG--QQ-PFALLNEPEP
Mflv_4241|M.gilvum_PYR-GCK DPEDDLPSANYGGDF-----ETTAIPRYDSAKPAD--QQQPFALLNDPEP
MSMEG_2370|M.smegmatis_MC2_155 DPEDDLPSASYGGDF-----ETTAIPRYDSKAP----DQSAFSMVSEPEP
TH_4069|M.thermoresistible__bu DPEDDLSST-YGGDI-----ETTAIPSYPSTGTAS--AQSPFALTGEPEP
MAB_3332c|M.abscessus_ATCC_199 DPEDDVPSATYGGDF-----ETTAIPQYQAERLTSSHNVKEVGPLYDPAP
Mb3030c|M.bovis_AF2122/97 DPEDDLTPARYAGDFG--SGTTTVIPPYDAASS--GVGNSGYSLIEAAEP
Rv3005c|M.tuberculosis_H37Rv DPEDDLTPARYAGDFG--SGTTTVIPPYDAASS--GVGNSGYSLIEAAEP
MMAR_1707|M.marinum_M DPEDDLTPAKYSSDFGS-AGTTTVIPPYDPTNS--GAVPSGYNLMDAQEP
MUL_1944|M.ulcerans_Agy99 DPEDDLTPAKYSSDFGS-AGTTTVIPPYDPTNS--GAVPSGYNLMDAQEP
MLBr_01698|M.leprae_Br4923 DPEDDLTPVGYPGDF----GTTTVIPYSDPDHLK-GPGGTGYNLLDQQEP
MAV_3854|M.avium_104 DPEDDLTPVGYPGDFNPSTGTTTVIPYGGAAAVA-GSGAAGYHLLEQQEP
*****:... * .*: **.** . *
Mvan_2120|M.vanbaalenii_PYR-1 LPYVQPGTGLAPGSYGS-------------------TAAPTEVGV---ID
Mflv_4241|M.gilvum_PYR-GCK LPYVQPSIGLAPGAYGS-------------------TAAPTEVG----VD
MSMEG_2370|M.smegmatis_MC2_155 LPYVQPGLHAPMGAY---------------------PAEPVEIDRNDVVD
TH_4069|M.thermoresistible__bu LPYVQPDDGSSFANYSAGAASSFSTGPASSFPAGSFPAGPAEVGTDELTE
MAB_3332c|M.abscessus_ATCC_199 LPYAEPATTQ-------------------------ISAEAVHARHAAPWG
Mb3030c|M.bovis_AF2122/97 LPYVQPQPG------------------------RQVPAGSAGIDMD--DD
Rv3005c|M.tuberculosis_H37Rv LPYVQPQPG------------------------RQVPAGSAGIDMD--DD
MMAR_1707|M.marinum_M LPYVQPQPGA-----------------------RHIPATPAALDMDE-DD
MUL_1944|M.ulcerans_Agy99 LPYVQPQPGA-----------------------RHIPATPAALDMDE-DD
MLBr_01698|M.leprae_Br4923 LPYVQPQ--A-----------------------RHAVAEPTEIDSDQ-DN
MAV_3854|M.avium_104 LPYVQPHSAA-----------------------RHAAPEPTDDD-DE-HH
***.:* . ..
Mvan_2120|M.vanbaalenii_PYR-1 PDRRD-DRRGTQDLGLLVLRVAVGVLLIGHGLQKVFGWWGGPGLDGFRDT
Mflv_4241|M.gilvum_PYR-GCK PDRHSGDRRGTQDLGLLLLRVAVGALLIGHGLQKVFGLWGGPGLGGFRDQ
MSMEG_2370|M.smegmatis_MC2_155 DQVRAAGRRGTQDLGLLILRVAIGGLLILHGLQKAFGWWGGPGFDGFGTS
TH_4069|M.thermoresistible__bu DRIKAAGRRGTMDLGLMLIRVGLGALLVVHGLQQAFGWWGGDGLGGLRDA
MAB_3332c|M.abscessus_ATCC_199 TQDPAGDRRGTQDLGLLLLRVGVGAVLIAHGLRKVFGWWGGTGLSGFEAT
Mb3030c|M.bovis_AF2122/97 ERVRAAGRRGTQNLGLLILRVGLGAVLIAHGLQKLFGWWDGQGLAGFQNS
Rv3005c|M.tuberculosis_H37Rv ERVRAAGRRGTQNLGLLILRVGLGAVLIAHGLQKLFGWWDGQGLAGFQNS
MMAR_1707|M.marinum_M ERIRAASRRGTQNFGLLILRVGLGAVLIAHGLQKLFGWWGGSGVTAFKNS
MUL_1944|M.ulcerans_Agy99 ERIRAASRRGTQNFGLLILRVGLGAVLIAHGLQKLFGWWGGSGVTAFKNS
MLBr_01698|M.leprae_Br4923 ERLHTVGRRGTQHLGLLVLRVGLGVVLAAQGLHKLFGWWGGQGLTGFKNS
MAV_3854|M.avium_104 DRLLDVGRRGTQHLGLLVLRAGLGVVLGAHGLQKLFGWWGGSGVTGLRNS
.**** .:**:::*..:* :* :**:: ** *.* *. .:
Mvan_2120|M.vanbaalenii_PYR-1 LTEVGFRHADILTYVAAGGQIAAGVLLVIGLFTPIAAAGALGYLITSVLA
Mflv_4241|M.gilvum_PYR-GCK LTDVGFRNADILSYVAAGGQIAAGVLLVLGLFTPIAAAGALGYLVTATLA
MSMEG_2370|M.smegmatis_MC2_155 LDDMGFKYSGILTYVATGGQIAAGVLLVLGLFTPIAAAGALAYGINGLLA
TH_4069|M.thermoresistible__bu LTESGFRYAEALTYAVAGAQIGAGVLLVLGLFTPLAAAGALAYLINVLLA
MAB_3332c|M.abscessus_ATCC_199 LGDRGFKYADILTYVGVTAELGAGVLLVLGLLTPLAGAAALAFTVNVLLS
Mb3030c|M.bovis_AF2122/97 LSDIGYQHAEILAYVSAGGEIVAGVLLVLGLFTPLAAAGALAFLINGLLA
Rv3005c|M.tuberculosis_H37Rv LSDIGYQHAEILAYVSAGGEIVAGVLLVLGLFTPLAAAGALAFLINGLLA
MMAR_1707|M.marinum_M LSDVGFQHADILAYVGAGGEIVVGVLLVLGLFTPLAGAGALAFLINGTLA
MUL_1944|M.ulcerans_Agy99 LSDVGFQHADILAYVGAGGEIVVGVLLVLGLFTPLAGAGALAFLMNGTLA
MLBr_01698|M.leprae_Br4923 LTQVGYQHADILAYVSAGGEAVAGVLLVLGLFAPVVAAGALAFLINGLLA
MAV_3854|M.avium_104 LSDVGYQHADILAYVSAGGELVAGVLLVLGLFTPLAAAGALAFLINGLLA
* : *:: : *:*. . .: .*****:**::*:..*.**.: :. *:
Mvan_2120|M.vanbaalenii_PYR-1 EATLAHEEARLSSFLTDGHEYQVVLVCAVAAIILVGPGRYGLDAGRGWAR
Mflv_4241|M.gilvum_PYR-GCK EATLAHDDARLSSFLTDGHEYQIVLLVVVAAIILVGPGRYGLDAGRGWAR
MSMEG_2370|M.smegmatis_MC2_155 EAMIAHEQARLSEFFHDGHQYRLVILAATAAIILTGPGRYGFDAGRGWAR
TH_4069|M.thermoresistible__bu G--ISANNGALPFFLPEGYEFEITLIVVAAALVLTGPGRYGLDAGRGWAR
MAB_3332c|M.abscessus_ATCC_199 D-MVSDKANRYAIFWPEGHEFELLMIVAIVAVILVGPGRYGFDAGRGWAR
Mb3030c|M.bovis_AF2122/97 GISAQHSR-PVAYFLQDGHEYQITLVVMAVAVILSGPGRYGLDAARGWAH
Rv3005c|M.tuberculosis_H37Rv GISAQHSR-PVAYFLQDGHEYQITLVVMAVAVILSGPGRYGLDAARGWAH
MMAR_1707|M.marinum_M NVSARPHS-QFSYFLPDGHEYQITLVVMAVAVILSGPGRYGLDAGRGWAH
MUL_1944|M.ulcerans_Agy99 NVSARPHS-QFSYFLPDDHEYQITLVVMAVAVILSGPGRYGLDAGRGWAH
MLBr_01698|M.leprae_Br4923 ---AWPHSPLFSFFLPDGNEHQITLIVMDVTVILCGPGRYGLDAGRRWAY
MAV_3854|M.avium_104 TISARPHAHTFSFFLPQGHEYQITLIVMATAVILCGPGRYGLDARRGWAH
. * :. :..: :: .:::* ******:** * **
Mvan_2120|M.vanbaalenii_PYR-1 RPFVGSFAALLLGIGAGVAIWVLLNGTNPLA
Mflv_4241|M.gilvum_PYR-GCK RPFVGSIAALILGAGAGVAIWVLLNGANPLG
MSMEG_2370|M.smegmatis_MC2_155 RPFVGSFVALLIGIGAGIGIWALLNGGNPLS
TH_4069|M.thermoresistible__bu RPFIGSFLALLLGVGAGIAIWVLLNGANPLG
MAB_3332c|M.abscessus_ATCC_199 RPFIGSFAAVVLGFGGAAAIWVFLNGTNPLA
Mb3030c|M.bovis_AF2122/97 RPFIGSFVALLGGIAAGIAVWVLLNGANPLA
Rv3005c|M.tuberculosis_H37Rv RPFIGSFVALLGGIAAGIAVWVLLNGANPLA
MMAR_1707|M.marinum_M RPFIGSFVALLTGIAAGIAIWVLLNGVNPVA
MUL_1944|M.ulcerans_Agy99 RPFIGSFVALLTGIAAGIAIWVLLNGVNPVA
MLBr_01698|M.leprae_Br4923 RPFIGSFIVLIAGIAAGIAVWVLLNGVNPLA
MAV_3854|M.avium_104 RPFIGSFVALLAGIAAGVGVWVALNGVNPIG
***:**: .:: * ... .:*. *** **:.