For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TKYEYDRIPYLVAYQNNSGVRDVYGGVAELVVLESYLLKPKTVESDTGAAPAATSDTGAAPAATSDTVLV FMHPIGGGAYLPMINALARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKNRLGYSKVVLAGWSG GGSLSAYYQQQAQNPTVTASPSGDGPDLTKLDLIPADGIMLLAAHISRHGTMTEWLDASILDESDPTKRD PELDLYNPDNPNQPPYSQEFLERYREAQIARNRRITKWVKEKLSELRANGRPDDEFAFVVHGTMADPRWL DPTVDPNERTPGTCYLGDPQVVNMSPVGLARFCTLRSWLSQWSFDDAHGDAVKCGPDIAVPALVIGNLAD DACTPSHTRRIFEAIGHQDKEMHEISGANHYYAGPDQRDKLREAVGIVTDWLKRHDFAGTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1896 | - | - | 100% (412) | hypothetical protein Mvan_1896 |
| M. vanbaalenii PYR-1 | Mvan_0405 | - | 1e-55 | 39.62% (318) | hypothetical protein Mvan_0405 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0278c | - | 3e-58 | 40.07% (307) | hypothetical protein Mb0278c |
| M. gilvum PYR-GCK | Mflv_4464 | - | 0.0 | 90.29% (412) | hypothetical protein Mflv_4464 |
| M. tuberculosis H37Rv | Rv0272c | - | 1e-57 | 40.07% (307) | hypothetical protein Rv0272c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4333 | - | 2e-61 | 41.51% (318) | hypothetical protein MAB_4333 |
| M. marinum M | MMAR_1495 | - | 0.0 | 81.51% (411) | hypothetical protein MMAR_1495 |
| M. avium 104 | MAV_4023 | - | 0.0 | 85.01% (407) | hypothetical protein MAV_4023 |
| M. smegmatis MC2 155 | MSMEG_2074 | - | 0.0 | 86.98% (407) | hypothetical protein MSMEG_2074 |
| M. thermoresistible (build 8) | TH_0902 | - | 0.0 | 84.44% (405) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1196 | - | 8e-58 | 40.25% (318) | hypothetical protein MUL_1196 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1896|M.vanbaalenii_PYR-1 -------------MTKYEYDRIPYLVAYQNNSGVRDVYGGVAELVVLESY
Mflv_4464|M.gilvum_PYR-GCK -------------MTKYEYDRIPYLVAYQNNSAVRDVYGGVAELVVLESY
MMAR_1495|M.marinum_M ------------MATRHEYDRIPYLVAFQNNSGVRDVYGGLAEITVLESY
MAV_4023|M.avium_104 --------------MKHEYDRIPYLVAFQNNSGVRDVYGGLAEITVLESY
MSMEG_2074|M.smegmatis_MC2_155 ------MTTTTEAPVKHEYDRIPYLVAYQNNSTVRDVYGGVAELVVLESY
TH_0902|M.thermoresistible__bu MTDTAKDTVTTPTPTKHEYDRIPYLIAFENTTGVRDVYGGVAELVVLESH
Mb0278c|M.bovis_AF2122/97 -----------MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHS
Rv0272c|M.tuberculosis_H37Rv -----------MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHS
MUL_1196|M.ulcerans_Agy99 -----------MSAATGTPEINREFVGLSSPTAGRAGAGGHPCQGLYHRA
MAB_4333|M.abscessus_ATCC_1997 --------------MPTQVTVEREFIGLPSPTAGRGGAGGHPCQGLYHRA
::. . : * ** . : .
Mvan_1896|M.vanbaalenii_PYR-1 LLKPKTVESDTGAAPAATSDTGAAPAATSDTVLVFMHPIGGGAYLPMINA
Mflv_4464|M.gilvum_PYR-GCK LLKPKTVESAAGAAPAATSDT----------VLVFMHPIGGGAYLPMINA
MMAR_1495|M.marinum_M LLKPKDKPSET--------------------VLVFMHPIGGGAYLPMINA
MAV_4023|M.avium_104 LLKPKNKPSDT--------------------VLVFMHPIGGGAYLPMINA
MSMEG_2074|M.smegmatis_MC2_155 LLRPKNRPSDT--------------------VLVFMHPIGGGAYLPMING
TH_0902|M.thermoresistible__bu LLRPKNRPSDT--------------------VLVFMHPIGGGAYLPMINA
Mb0278c|M.bovis_AF2122/97 VGRKPK------------------------VALIAAHYQIDFSEHYLAEY
Rv0272c|M.tuberculosis_H37Rv VGRKPK------------------------VALIAAHYQIDFSEHYLAEY
MUL_1196|M.ulcerans_Agy99 AGTRPT------------------------VAMIATHYQIDFSEHYLADY
MAB_4333|M.abscessus_ATCC_1997 AGTKPK------------------------VAFIATHYQIDFSEHYIAEY
.:: * . : : :
Mvan_1896|M.vanbaalenii_PYR-1 LARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKNRLGYSKVVLA
Mflv_4464|M.gilvum_PYR-GCK LARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKNRLGYQKVVLA
MMAR_1495|M.marinum_M LARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKKRLGYSKVVLA
MAV_4023|M.avium_104 LARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKKRLGYTKVVLA
MSMEG_2074|M.smegmatis_MC2_155 LARAGHHVIYCNSRFRGTDSALLMEKVVEDLGECIKDAKNRLGYSKVVLA
TH_0902|M.thermoresistible__bu LARAGHHVIYCNSRFRGTDSALLMEKVVQDLGECIKDAKNRLGYRRVVLA
Mb0278c|M.bovis_AF2122/97 MAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRWLREVQGVETVVLL
Rv0272c|M.tuberculosis_H37Rv MAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRWLREVQGVETVVLL
MUL_1196|M.ulcerans_Agy99 MAARGIGFLGWNTRFRGFESNFALDHALVDIGVGVRWLREVAGAETVVLL
MAB_4333|M.abscessus_ATCC_1997 LARHGYGFLGWNTRFRGFESQFLLDHALVDIGVGVRWLQEQAGVETVLLL
:* * .: *:**** :* : :::.: *:* :: :: * *:*
Mvan_1896|M.vanbaalenii_PYR-1 GWSGGGSLSAYYQQQAQNPTVTASPSGDGPDLTKLDLIPADGIMLLAAHI
Mflv_4464|M.gilvum_PYR-GCK GWSGGGSLSVFYQQQAQHPTVTASPSGDGPDLTKLGLIPADGIMLLAAHI
MMAR_1495|M.marinum_M GWSGGGSLSVLYQQQAQRPTLTASPSGDGPDLTQLDLPAADAIMLLAAHI
MAV_4023|M.avium_104 GWSGGGSLSVFYQQQAQNPTITSSPSGDGPDLTKLDLIPADGIMLLAAHI
MSMEG_2074|M.smegmatis_MC2_155 GWSGGGSLSVFYQQQAQNPTVTASPSGDGPDLTQLGLIPADGIMLLAAHI
TH_0902|M.thermoresistible__bu GWSGGGSLSVFYQQQAQHPTVTASPSGDGPDLTRLGLIPADGLMLLAAHI
Mb0278c|M.bovis_AF2122/97 GNSGGGSLMAAYQSQAVDPNVTP-LDGMRPAAGVTELPAADAYVAAAAHL
Rv0272c|M.tuberculosis_H37Rv GNSGGGSLMAAYQSQAVDPNVTP-LDGMRPAAGVTELPAADAYVAAAAHP
MUL_1196|M.ulcerans_Agy99 GNSGGGSLMAAYQSQAVDPNVTP-LAGTRPAAGVNELPTADGYVATAAHP
MAB_4333|M.abscessus_ATCC_1997 GNSGGGSLMAAYQSQATAPKVKP-LEGMRPAEGLDGLLPAAGYVATAAHL
* ****** . **.** *.:.. * * * .* . : ***
Mvan_1896|M.vanbaalenii_PYR-1 SRHGTMTEWLDASILDESDPTKRDPELDLYNPDNPNQPPYSQEFLERYRE
Mflv_4464|M.gilvum_PYR-GCK SRHGTMTEWMDASILDESDPSKRDPELDLYNPDNPHQPPYTQEFLERYHQ
MMAR_1495|M.marinum_M SRHGTLTEWLDASIIDESDPSKRDPDLDLYDPNNPNQPPYSAQFLTRYRQ
MAV_4023|M.avium_104 SRHGTLTEWLDASILDESDPTKRDPELDLYDSDNPNQPPYSQEFLDRYRQ
MSMEG_2074|M.smegmatis_MC2_155 SRHGTLTEWLDASILDESDPTKRDPELDLYNPDNPNQPPYSPEFLDRYRA
TH_0902|M.thermoresistible__bu SRHGTLTEWLDASILDETDPTKRDPELDLYNPDNPNQPPYSQEFLDRYRA
Mb0278c|M.bovis_AF2122/97 GRPDVLTAWMDAAVIDENDPVATDPELDLFD--ERNGPPYSPEFISRYRS
Rv0272c|M.tuberculosis_H37Rv GRPDVLTAWMDAAVIDENDPVATDPELDLFD--ERNGPPYSPEFISRYRS
MUL_1196|M.ulcerans_Agy99 GRPEVLTAWMDAAVIDENDPVATDPDLDLFN--ERNGPPYSPEFLSRYRA
MAB_4333|M.abscessus_ATCC_1997 GRPDVLTDWMDASVIDESDPASTDPALDLFN--QANGPAYAPEFVVKYRE
.* .:* *:**:::**.** ** ***:: : : *.*: :*: :*:
Mvan_1896|M.vanbaalenii_PYR-1 AQIARNRRITKWVKEKLSELRANGRPDD---EFAFVVHGTMADPRWLDPT
Mflv_4464|M.gilvum_PYR-GCK AQIARNRRITKWVKEKLAELKAAGRPED---EFAFVVHGTMADPRWLDPT
MMAR_1495|M.marinum_M AQIDRNRRITAWVKDKLAELEASGRPDSDVAEFCFVVHGTMADPRWLDPS
MAV_4023|M.avium_104 AQIERNRRITAWVKAKLAELKAAGRPDD---EFGFVVHGTMADPRWLDPT
MSMEG_2074|M.smegmatis_MC2_155 AQIARNRRITKWVKEKLAELKAAGRPDD---EFAFVVHGTMADPRWLDPT
TH_0902|M.thermoresistible__bu AQIARNRRITAWVKDKLAELRAAGRPDD---EFAFVVHGTMADPRWLDPT
Mb0278c|M.bovis_AF2122/97 AQVKRNHTITDWAESELKRVRAAGFSDR-----PFSVMRTWADPRMVDPS
Rv0272c|M.tuberculosis_H37Rv AQVKRNHTITDWAESELKRVRAAGFSDR-----PFSVMRTWADPRMVDPS
MUL_1196|M.ulcerans_Agy99 AQAARNESITDWAEDELKRVRAAGFSDR-----PFTVMRTWADPRMVDAS
MAB_4333|M.abscessus_ATCC_1997 GQAARNHRITAWALEELARVRAAGFSDR-----AFTVHRTWADPRMVDPT
.* **. ** *. :* .:.* * .: * * * **** :*.:
Mvan_1896|M.vanbaalenii_PYR-1 VDPNERTPGTCYLGDPQVVNMSPVGLARFCTLRSWLSQWSFDDAHGDAVK
Mflv_4464|M.gilvum_PYR-GCK VDPNERAPGTCYLGDPQVVNMSPVGLARFCTLRSWLSQWSYDDANGDAVK
MMAR_1495|M.marinum_M VDPNERTPGTCYLGDPQVVNMSPVGLARFCTLRSWLSQWSYDDARGDGVV
MAV_4023|M.avium_104 VDPNERTPGTCYLGDPRVVNMSPVGLARFCTLRGWLSQWSYDDARGDALA
MSMEG_2074|M.smegmatis_MC2_155 VDPNDRKPGTCYLGDPQVVNNSPVGLARFCTLRSWLSQWSYDDANGDAVK
TH_0902|M.thermoresistible__bu VDPNERTPGTCYLGDPQVVNMSPVGLARFCTLRSWLSQWSYDDANADGVR
Mb0278c|M.bovis_AF2122/97 IEPTKRRPNQCYAGTPVKANRSAHGIAAACTLRGWLGMWSLRVAQTRAAP
Rv0272c|M.tuberculosis_H37Rv IEPTKRRPNQCYAGTPVKANRSAHGIAAACTLRGWLGMWSLRVAQTRAAP
MUL_1196|M.ulcerans_Agy99 IEPTNREPNLCYAGKPVRANRSARGIAAACTLRNWLGMWSLRVAQARAAP
MAB_4333|M.abscessus_ATCC_1997 LEPTKRPANLCYAGVPVKANRSTFGIGGATTLKNWLGMWSLSHAQTRAEP
::*..* .. ** * * .* *. *:. **:.**. ** *. .
Mvan_1896|M.vanbaalenii_PYR-1 CGPDIAVPALVIGNLADDACTPSHTRRIFEAIGHQDKEMHEISGANHYYA
Mflv_4464|M.gilvum_PYR-GCK AGPDIAVPALVIGNLADDACTPSHTRRIFEAIRHEDKEMHEIAGANHYYA
MMAR_1495|M.marinum_M CGRDLAVPALVIGNLADDACTPSHTRRLFEAIGHADKEMYEIPGATHYYA
MAV_4023|M.avium_104 CGPDIAIPALVIGNLADDACTPSHTRRLFQAIGHHDKEMHEIPGATHYYA
MSMEG_2074|M.smegmatis_MC2_155 AGPDIAVPALVIGNLADDACTPSHTRRLFEAIGHPDKEMHEIPGANHYYA
TH_0902|M.thermoresistible__bu CGRDVAVPTLVIGNLADDACTPSHTRRLYEAIGHPDKEMHEIPGANHYYA
Mb0278c|M.bovis_AF2122/97 HLARITCPALVLNAEADTGIFPSDAQQIYDGLASSDKTQVSID-TDHYFT
Rv0272c|M.tuberculosis_H37Rv HLARITCPALVLNAEADTGIFPSDAQQIYDGLASSDKTQVSID-TDHYFT
MUL_1196|M.ulcerans_Agy99 HLARITCPALVINADADTGVFPSDAQCIYDGLASTDKARASID-TDHYFT
MAB_4333|M.abscessus_ATCC_1997 HLADVTVPALVINADGDTGVFPSDARRIYGALGATDKSQATID-ADHYFQ
:: *:**:. .* . **.:: :: .: ** * : **:
Mvan_1896|M.vanbaalenii_PYR-1 GPDQRDKLREAVGIVTDWLKRHDFAGTR----------
Mflv_4464|M.gilvum_PYR-GCK GADQRDKLREAVGIVTEWLQRHDFAGAR----------
MMAR_1495|M.marinum_M GPDQRDKLGQAVDIVTDWLLRHDFASRP----------
MAV_4023|M.avium_104 GPDQRDALRSAVGIVTDWLVRHDFAEKA----------
MSMEG_2074|M.smegmatis_MC2_155 GPDQRDTLRQAVGICTDWLHRHGFSLPVASAATEGAAQ
TH_0902|M.thermoresistible__bu GPDQRDKLRQAVTIVTDWLNRHGLSQPVKEGM------
Mb0278c|M.bovis_AF2122/97 TPGARS---EQADTIAKWIAKRWR--------------
Rv0272c|M.tuberculosis_H37Rv TPGARS---EQADTIAKWIAKRWR--------------
MUL_1196|M.ulcerans_Agy99 TPGARD---EQADTITNWIAKRWQ--------------
MAB_4333|M.abscessus_ATCC_1997 NPGARQ---EQADTIAEWASKRW---------------
.. *. . . :.* ::