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PKFLDAVAGFGVTFGSMFKKPVTEEYPEKPGPVAKRYHGRHQLNRYPDGLEKCIGCELCAWACPADAIFV EGADNTESERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTNDYEMADDNRSDLIYGKDKLLAPL EPGMEAPPHAMAPDSTDDDYYLGNIKPAARDAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1877 | - | - | 100% (174) | NADH dehydrogenase subunit I |
| M. vanbaalenii PYR-1 | Mvan_4108 | - | 4e-06 | 31.75% (63) | putative glutamate synthase (NADPH) small subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3177 | nuoI | 4e-86 | 86.59% (164) | NADH dehydrogenase subunit I |
| M. gilvum PYR-GCK | Mflv_4489 | - | 5e-97 | 92.00% (175) | NADH dehydrogenase subunit I |
| M. tuberculosis H37Rv | Rv3153 | nuoI | 1e-85 | 85.98% (164) | NADH dehydrogenase subunit I |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2142 | - | 2e-85 | 83.43% (169) | NADH dehydrogenase subunit I |
| M. marinum M | MMAR_1475 | nuoI | 5e-87 | 85.98% (164) | NADH dehydrogenase I (chain I) NuoI (NADH- ubiquinone |
| M. avium 104 | MAV_4041 | - | 1e-87 | 88.41% (164) | NADH dehydrogenase subunit I |
| M. smegmatis MC2 155 | MSMEG_2055 | nuoI | 9e-91 | 87.50% (168) | NADH dehydrogenase subunit I |
| M. thermoresistible (build 8) | TH_1087 | nuoI | 5e-90 | 82.18% (174) | PROBABLE NADH DEHYDROGENASE I (CHAIN I) NUOI |
| M. ulcerans Agy99 | MUL_2467 | nuoI | 3e-87 | 85.98% (164) | NADH dehydrogenase subunit I |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1877|M.vanbaalenii_PYR-1 ---------------------------MPKFL----DAVAGFGVTFGSMF
Mflv_4489|M.gilvum_PYR-GCK ---------------------------MPKFL----DAVAGFGVTFGSMF
MSMEG_2055|M.smegmatis_MC2_155 ---------------------------MPKFL----DALAGFAVTLGSMF
TH_1087|M.thermoresistible__bu ---------------------------LSRFL----EAIAGFGVTLGAMF
MAB_2142|M.abscessus_ATCC_1997 ---------------------------MPDLLRRSADAMAGFWVTFSSMF
Mb3177|M.bovis_AF2122/97 MANTDRPALPHKRAVPPSRADSGPRRRRTKLL----DAVAGFGVTLGSMF
Rv3153|M.tuberculosis_H37Rv MANTDRPALPHKRAVPPSRADSGPRRRRTKLL----DAVAGFGVTLGSMF
MMAR_1475|M.marinum_M ---------------------------MAKFL----DSIAGFGVTFGSMF
MUL_2467|M.ulcerans_Agy99 ---------------------------MAKFL----DSIAGFGVTFGSMF
MAV_4041|M.avium_104 ---------------------------MAKFL----DAVAGFGVTFASMF
. :* :::*** **:.:**
Mvan_1877|M.vanbaalenii_PYR-1 KKPVTEEYPEKPGPVAKRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
Mflv_4489|M.gilvum_PYR-GCK KKPVTEEYPEKPGPVAKRYHGRHQLNRYADGLEKCIGCELCAWACPADAI
MSMEG_2055|M.smegmatis_MC2_155 KKPITEGYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
TH_1087|M.thermoresistible__bu KKPLTEQYPEQPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
MAB_2142|M.abscessus_ATCC_1997 KKRLTEQYPEKKQPTAPRYHGRHQLNRYADGLEKCIGCELCAWACPADAI
Mb3177|M.bovis_AF2122/97 KKTVTEEYPERPGPVAARYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
Rv3153|M.tuberculosis_H37Rv KKTVTEEYPERPGPVAARYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
MMAR_1475|M.marinum_M KKTVTEEYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
MUL_2467|M.ulcerans_Agy99 KKTVTEEYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
MAV_4041|M.avium_104 KKHVTEEYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAI
** :** ***: *.* ***********.*********************
Mvan_1877|M.vanbaalenii_PYR-1 FVEGADNTESERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
Mflv_4489|M.gilvum_PYR-GCK FVEGADNTEAERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
MSMEG_2055|M.smegmatis_MC2_155 YVEGADNTADERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTTE
TH_1087|M.thermoresistible__bu YVEGADNTEAQRYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
MAB_2142|M.abscessus_ATCC_1997 FVEGADNSEEERFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
Mb3177|M.bovis_AF2122/97 YVEGADNTEEERFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTYD
Rv3153|M.tuberculosis_H37Rv YVEGADNTEEERFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTYD
MMAR_1475|M.marinum_M YVEGADNTDEQRFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
MUL_2467|M.ulcerans_Agy99 YVEGADNTDEQRFSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTND
MAV_4041|M.avium_104 YVEGADNTEELRYSPGERYGRVYQINYLRCIGCGLCVEACPTRALTMTND
:******: *:***********************:*********** :
Mvan_1877|M.vanbaalenii_PYR-1 YEMADDNRSDLIYGKDKLLAPLEPGMEAPPHAMAPDSTDDDYYLGNIKP-
Mflv_4489|M.gilvum_PYR-GCK YEMADDNRADLIYGKDKLLAPLEPGMGAPPHAMAPGATDEDYYRGTVSPS
MSMEG_2055|M.smegmatis_MC2_155 YEMADDNRADLIWGKDKLLAPLQEGMQAPPHDMAPGKTDDDYYLGNVTPI
TH_1087|M.thermoresistible__bu YEMADDNRADLIWGKDKLLAPLQPGMVPPPHPMAVGATDEDYYLGRVSPI
MAB_2142|M.abscessus_ATCC_1997 YEMADDNRADLIYGKDKLLAPLQPGMTAPPHAMYPGATDTDYYLGNLPKA
Mb3177|M.bovis_AF2122/97 YELADDNRADLIYEKDRLLAPLLPEMAAPPHPRAPGATDKDYYLGNVTAE
Rv3153|M.tuberculosis_H37Rv YELADDNRADLIYEKDRLLAPLLPEMAAPPHPRTPGATDKDYYLGNVTAE
MMAR_1475|M.marinum_M YELADDNRADLIYEKDRLLAPLQPEMTAPPHPRAAGATDKDYYLGNVTAE
MUL_2467|M.ulcerans_Agy99 YELADDNRADLIYEKDRLLAPLQPEMTAPPHPRAAGATDKDYYLGNVTAE
MAV_4041|M.avium_104 YEMADDNRADLIYEKDRLLAPLLPEMTAPPHPRAPGATDKDYYLGNVTAH
**:*****:***: **:***** * .*** . ** *** * :
Mvan_1877|M.vanbaalenii_PYR-1 AAR---------DAR
Mflv_4489|M.gilvum_PYR-GCK AEA---------DAR
MSMEG_2055|M.smegmatis_MC2_155 TPVP----SGTEDAR
TH_1087|M.thermoresistible__bu T----------EDVR
MAB_2142|M.abscessus_ATCC_1997 G----------EEVR
Mb3177|M.bovis_AF2122/97 GLRGVRESQTTGDSR
Rv3153|M.tuberculosis_H37Rv GLRGVRESQTTGDSR
MMAR_1475|M.marinum_M GLR---ETQKTGESR
MUL_2467|M.ulcerans_Agy99 GLR---ETQKTGESR
MAV_4041|M.avium_104 GLR---EAQRAGEPR
: *