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TRYAVSSATPVLSRPDGTVQVGWDPRRAVVVHPPAGLPAAVLAELLRALQGAATAPELQKVAAGHGVAAT VVAGLLSHLVDAGVVVPTPPGVDRSPAVRVHGSGPLTDLLTASLRCSNVRISQSTRTHASTAGADLVVLT DYLVADPRVVRELHDAGVAHLPVRVRDGTGLIGPLVIPGVTSCLRCGDLHRSDRDPAWPAVAAQLCRTVG SADRPTILATAALALREIEHVLRAVRGAGTDSPSTLDTTLEFEVATGTSTARRWSRHPSCGC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1811 | - | - | 100% (273) | hypothetical protein Mvan_1811 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3218 | - | 7e-86 | 58.57% (280) | hypothetical protein Mb3218 |
| M. gilvum PYR-GCK | Mflv_4657 | - | 1e-112 | 73.29% (277) | hypothetical protein Mflv_4657 |
| M. tuberculosis H37Rv | Rv3196 | - | 7e-86 | 58.57% (280) | hypothetical protein Rv3196 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3502 | - | 6e-60 | 45.49% (277) | hypothetical protein MAB_3502 |
| M. marinum M | MMAR_1368 | - | 1e-85 | 57.82% (275) | hypothetical protein MMAR_1368 |
| M. avium 104 | MAV_4140 | - | 9e-87 | 58.78% (279) | hypothetical protein MAV_4140 |
| M. smegmatis MC2 155 | MSMEG_1955 | - | 1e-76 | 54.51% (277) | hypothetical protein MSMEG_1955 |
| M. thermoresistible (build 8) | TH_1132 | - | 3e-66 | 62.87% (202) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2508 | - | 2e-85 | 58.18% (275) | hypothetical protein MUL_2508 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1811|M.vanbaalenii_PYR-1 ----------------MTRYAVSSATPVLSRPDGTVQVGWDPRRAVVVHP
Mflv_4657|M.gilvum_PYR-GCK ----------MTRCRTMTRYALSPATPVLSRPDGTVQVGWDPRKAVVVRP
Mb3218|M.bovis_AF2122/97 MSARSVAPSQVMRRAASALYSLNPAMPVLLRPDGAVQVGWDPRRAVLVRP
Rv3196|M.tuberculosis_H37Rv MSARSVAPSQVMRRAASALYSLNPAMPVLLRPDGAVQVGWDPRRAVLVRP
MMAR_1368|M.marinum_M ---------------MPALYSLDPAMPVLLRPDGAVQVGWDPQRAVLIRP
MUL_2508|M.ulcerans_Agy99 ---------------MPALYSLDPAMPVLLRPDGAVQVGWDPQRAVLIRP
MAV_4140|M.avium_104 MPAATVS-------TPATTYALDPAMPVLLRPDGAVQVGWDPRRAVLVRP
MSMEG_1955|M.smegmatis_MC2_155 ---------------MTARFTLTPDRPVLLRPDGAVQIGWDPRTAVRVRP
TH_1132|M.thermoresistible__bu --------------------------------------------------
MAB_3502|M.abscessus_ATCC_1997 --------MPQWVMSSEPTFTLDPARPVLPRPDDGIQIGWTPRHAVVVHT
Mvan_1811|M.vanbaalenii_PYR-1 PAGLPAAVLAELLRALQGAATAPELQKVAAGHG-VAATVVAGLLSHLVDA
Mflv_4657|M.gilvum_PYR-GCK PAGLPGSVLAELLRALQGVATAPQLQRLAAGHG-VDAPVVDGLVAHLVTR
Mb3218|M.bovis_AF2122/97 PRGLTATGLAALLRSMRSPIPITELQRQAAERGLVDGDAMANLVAQLVGA
Rv3196|M.tuberculosis_H37Rv PRGLTATGLAALLRSMRSPIPITELQRQAAERGLVDGDAMANLVAQLVGA
MMAR_1368|M.marinum_M PEGLTTTAVAELLRSMRSPIPITELQRHATGRGWVPGD-VANLVSQLVDA
MUL_2508|M.ulcerans_Agy99 PEGLTTTAVAELLRSMRSPIPITELQRHATGRGWVPGD-VANLVSQLVGA
MAV_4140|M.avium_104 PRGLAAAELARLLRSMCSPTPLSELQRRALEHGLTDADGLRNLVTQLVGA
MSMEG_1955|M.smegmatis_MC2_155 PDGMTPTQLTDLLHALQTGRSIEQLRSATEQFG--DPALVGDVLAALDSA
TH_1132|M.thermoresistible__bu ---------------------------------------LHDLLAALLRA
MAB_3502|M.abscessus_ATCC_1997 GSAAPTHAVRQLLSSLSDELSWEQIVNLRCAKDFRDPDDIRSLLEELVAA
: .:: *
Mvan_1811|M.vanbaalenii_PYR-1 GVVVPTPP-----GVDRSPAVRVHGSGPLTDLLTASLRCSNVRISQSTRT
Mflv_4657|M.gilvum_PYR-GCK GVVTEAPR-----TPVRSVAVRVHGDGPLADLLISSLRHANVRVSHSTRP
Mb3218|M.bovis_AF2122/97 GVATPLANPGNLDSRRRAASIRVHGRGPLSDLLVQALRCSGARIRHSSQP
Rv3196|M.tuberculosis_H37Rv GVATPLANPGNLDSRRRAASIRVHGRGPLSDLLVQALRCSGARIRHSSQP
MMAR_1368|M.marinum_M GVATRRHR----DRTGRTASIRIHGRGPLSDLLVQALRCSGARIGQSSQP
MUL_2508|M.ulcerans_Agy99 GVATRRHR----HRTGRTASIRIHGRGPLSDLLVQALRCSGARIGQSSQP
MAV_4140|M.avium_104 GVASECGR-----SGGRAPSVRIHGRGPLSELLVESLRCSGARIAHSSQP
MSMEG_1955|M.smegmatis_MC2_155 GVLVRRSA-----SPARTATIRIHGRGPLSELLAGSLRRSGARLQHTAES
TH_1132|M.thermoresistible__bu GLVRRTGR-----RPGRAASIRIHGRGPLSDLLAGSLRCTGNRVQHSTRS
MAB_3502|M.abscessus_ATCC_1997 GAVIRRIR----PTNPASPVIRLVGRGPLSDALAEALRHTSARIQHTTHS
* : :*: * ***:: * :** :. *: :::..
Mvan_1811|M.vanbaalenii_PYR-1 HASTAGA--DLVVLTDYLVADPRVVRELHDAGVAHLPVRVRDGTGLIGPL
Mflv_4657|M.gilvum_PYR-GCK NASSGRP--DLVVLTDYLVADPRLVRDLCDARVPHLPVRVRDGTGLVGPL
Mb3218|M.bovis_AF2122/97 HAAVTPAGVDLVVLSDYLVADPHMVRDLHTERVPHLPVRVRDGTGMVGPL
Rv3196|M.tuberculosis_H37Rv HAAVTPAGVDLVVLSDYLVADPHMVRDLHTERVPHLPVRVRDGTGMVGPL
MMAR_1368|M.marinum_M HAAVTRSAVDLVVLSDNLVAEPRLVRDLQREGIAHLPVRVRDGTGLVGPL
MUL_2508|M.ulcerans_Agy99 HAAVTRSAVDLVVLSDNLVAEPRLVRDLRREGIAHLPVRVRDGTGLVGPL
MAV_4140|M.avium_104 HAAVSGDDVDLVVLSDYLVADPRLVRDLHEQGVAHLPVRVRDGVGLVGPL
MSMEG_1955|M.smegmatis_MC2_155 YAT-PRPGTDLVVLADELVTEPRIVRELHRGRIAHLPVRVRDGTGLVGPL
TH_1132|M.thermoresistible__bu HAA-APAGTDLVVLADDLIAEPRVVRELHAAQIPHLPVRVRDHTGLIGPL
MAB_3502|M.abscessus_ATCC_1997 VHGKSWQHVDLAVLADDLIADTRLLRMLADAEVPHLSVRARDGTGLIGPM
**.**:* *:::.:::* * :.**.**.** .*::**:
Mvan_1811|M.vanbaalenii_PYR-1 VIPGVTSCLRCGDLHRSDRDPAWPAVAAQLCRTVGSADRPTILATAALAL
Mflv_4657|M.gilvum_PYR-GCK VIPSVTSCLRCADLHRSDRDAAWPAIAAQLSRTVGNADRATVLATAALAL
Mb3218|M.bovis_AF2122/97 VVPGVTSCLGCADLHRSDRDAAWPAIAAQLRDTVGVADRATLLATAALAL
Rv3196|M.tuberculosis_H37Rv VVPGVTSCLGCADLHRSDRDAAWPAIAAQLRDTVGVADRATLLATAALAL
MMAR_1368|M.marinum_M VIPGVTSCLRCADLHRSDRDPAWPAIAAQLRDTVGVADRATVLATAALAL
MUL_2508|M.ulcerans_Agy99 VIPGVTSCLRCADLHRSDRDPAWPAIAAQLRDTVGVADRATVLATAALAL
MAV_4140|M.avium_104 VIPGVTSCLSCADLHRRDRDAAWPVICAQLRDTVGVADRATVLATGALAL
MSMEG_1955|M.smegmatis_MC2_155 VIPGVTSCLHCADLHRADRDAAWPALAAQLRGTVGSASRATILATAALAL
TH_1132|M.thermoresistible__bu VIPGVTSCLGCGDLHRTDRDAAWPVVAAQLRGTVGAADRATVLATAALAL
MAB_3502|M.abscessus_ATCC_1997 VLPGITSCLECADRHRHDRDEQWPAVAAQLTGTVGVAAPATVLGTVAVAL
*:*.:**** *.* ** *** **.:.*** *** * .*:*.* *:**
Mvan_1811|M.vanbaalenii_PYR-1 REIEHVLRAVR-------GAGTDSPSTLDTTLEFEVATGTSTARRWSRHP
Mflv_4657|M.gilvum_PYR-GCK NEIDHIVRSLRPD---HPGAVAASPETLDTTLEFDVAAGTVQARRWTRHP
Mb3218|M.bovis_AF2122/97 SQVNRVIAAVRGQ---EATPE--PPSALNTTLEFDLNAGSIVARQWTRHP
Rv3196|M.tuberculosis_H37Rv SQVNRVIAAVRGQ---EATPE--PPSALNTTLEFDLNAGSIVARQWTRHP
MMAR_1368|M.marinum_M RQVNGVIAAVRDQ---ENPSD--PPPALNATLEFDLQAGSVVARYWARHP
MUL_2508|M.ulcerans_Agy99 RQINGVIAAVRDQ---ENPSD--PPSALNATLEFDLQAGSVVARYWARHP
MAV_4140|M.avium_104 SQVNRVIAAVRGQ---PAASDPAPPQTLNATLEFDLQAGAIVARRWDRHP
MSMEG_1955|M.smegmatis_MC2_155 RQVDLVIRAVSGTAGPDDPPE--PPATLDTTLELTADGYSMSFRRWSRHP
TH_1132|M.thermoresistible__bu EQVNRVVRAVLG----DDPAHSTPPPTLDTTLEFDVRVHSIVMRRWSRHP
MAB_3502|M.abscessus_ATCC_1997 AQIDRVLSAMRGQ-----PPG--PLATLNATLELDLATHALTARHWTAHP
::: :: :: . . :*::***: : * * **
Mvan_1811|M.vanbaalenii_PYR-1 SCGC-------
Mflv_4657|M.gilvum_PYR-GCK DCSC-------
Mb3218|M.bovis_AF2122/97 RCFC-------
Rv3196|M.tuberculosis_H37Rv RCFC-------
MMAR_1368|M.marinum_M LCSC-------
MUL_2508|M.ulcerans_Agy99 LCSC-------
MAV_4140|M.avium_104 LCSC-------
MSMEG_1955|M.smegmatis_MC2_155 DCQC-------
TH_1132|M.thermoresistible__bu ACSC-------
MAB_3502|M.abscessus_ATCC_1997 LCPCGAYFAGN
* *