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TNLSSAILDPLMAANPAGPRITYYDDATGERIELSTATLANWAAKTGNLLRDELGAMPGSRVAVLLPAHW QTAAVLFGIWWIGAEAVLSGDADIAMCTADRLADADASVGSGEIAVLSLDPFGKPVPDLPVGLTDYATAV RVHGDQIVPERQPGPALEGRSADEVLAAARASAASQGLTPADRVMSAARWDTADDVVDQLLALYAVGASL VLVANPDPALVERRRETEKLTRTTL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1725 | - | - | 100% (236) | hypothetical protein Mvan_1725 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3296 | - | 4e-89 | 70.48% (227) | hypothetical protein Mb3296 |
| M. gilvum PYR-GCK | Mflv_4738 | - | 1e-114 | 85.53% (235) | hypothetical protein Mflv_4738 |
| M. tuberculosis H37Rv | Rv3268 | - | 4e-89 | 70.48% (227) | hypothetical protein Rv3268 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3615 | - | 8e-73 | 61.02% (236) | hypothetical protein MAB_3615 |
| M. marinum M | MMAR_1273 | - | 2e-87 | 69.20% (224) | hypothetical protein MMAR_1273 |
| M. avium 104 | MAV_4233 | - | 4e-95 | 72.84% (232) | hypothetical protein MAV_4233 |
| M. smegmatis MC2 155 | MSMEG_1823 | - | 2e-96 | 72.96% (233) | hypothetical protein MSMEG_1823 |
| M. thermoresistible (build 8) | TH_4313 | - | 2e-05 | 27.31% (227) | PUTATIVE putative AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_2614 | - | 2e-87 | 69.20% (224) | hypothetical protein MUL_2614 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1725|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4738|M.gilvum_PYR-GCK --------------------------------------------------
Mb3296|M.bovis_AF2122/97 --------------------------------------------------
Rv3268|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1273|M.marinum_M --------------------------------------------------
MUL_2614|M.ulcerans_Agy99 --------------------------------------------------
MAV_4233|M.avium_104 --------------------------------------------------
MSMEG_1823|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3615|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4313|M.thermoresistible__bu VTLADLLDGVPEIAVHTLRADVSRDALAAGADRLAGVLRDLGMSTGEVVA
Mvan_1725|M.vanbaalenii_PYR-1 -----------------------------------MTNLSSAILDPLMAA
Mflv_4738|M.gilvum_PYR-GCK ---------------------------MTRSASTEVTNVSSAVLDPLMAA
Mb3296|M.bovis_AF2122/97 ----------------------------------------------MLRA
Rv3268|M.tuberculosis_H37Rv ----------------------------------------------MLRA
MMAR_1273|M.marinum_M ----------------------------------------------MLRA
MUL_2614|M.ulcerans_Agy99 ----------------------------------------------MLRA
MAV_4233|M.avium_104 --------------------------------MRQSSTLSAAILDPMLRA
MSMEG_1823|M.smegmatis_MC2_155 -----------------------------------MSTVSAAVLDPLLAA
MAB_3615|M.abscessus_ATCC_1997 -----------------------------------MTTLTALLLG---DV
TH_4313|M.thermoresistible__bu VMLPNEARTVAALFGVWRAGGVHTPLNPRAADAELRSQLEVLTPSVIVTD
Mvan_1725|M.vanbaalenii_PYR-1 NPAGPRITYY-----------------DDATGERIELSTATLANWAAKTG
Mflv_4738|M.gilvum_PYR-GCK NPAGPRITYY-----------------DDATGERIELSTATLANWAAKTG
Mb3296|M.bovis_AF2122/97 DPVGPRITYY-----------------DDATGERIELSAVTLANWAAKTG
Rv3268|M.tuberculosis_H37Rv DPVGPRITYY-----------------DDATGERIELSAVTLANWAAKTG
MMAR_1273|M.marinum_M DPVGPRITYY-----------------DDATGERIELSAVTLANWAAKTA
MUL_2614|M.ulcerans_Agy99 DPVGPRITYY-----------------DDATGERIELSAMTLANWAAKTA
MAV_4233|M.avium_104 DPVGPRITYY-----------------DDATGERIELSGVTLANWAAKTG
MSMEG_1823|M.smegmatis_MC2_155 DPAGPRITYY-----------------DDATGERIELSTVTLANWAAKTA
MAB_3615|M.abscessus_ATCC_1997 NNPSPRITYY-----------------DDATGERIELSTVTLANWAAKTA
TH_4313|M.thermoresistible__bu DQLAGRFADFGPPVVTGGGLDWSVARPGSAPAERRFDADVALLQFTSGTT
: . *:: : ..*..** : :* :::: *
Mvan_1725|M.vanbaalenii_PYR-1 N------------------LLRDELGAMPGSRVAVLLP-------AHWQT
Mflv_4738|M.gilvum_PYR-GCK N------------------LLRDELGATPGSRVAVLLP-------AHWQT
Mb3296|M.bovis_AF2122/97 N------------------LLRDELAAGPASRVAILLP-------AHWQT
Rv3268|M.tuberculosis_H37Rv N------------------LLRDELAAGPASRVAILLP-------AHWQT
MMAR_1273|M.marinum_M N------------------LLRDELAAGPQSRVAILLP-------AHWQT
MUL_2614|M.ulcerans_Agy99 N------------------LLRDELAAGPQSRVAILLP-------AHWQT
MAV_4233|M.avium_104 N------------------LLRDELGAGPASRVAILLP-------AHWQT
MSMEG_1823|M.smegmatis_MC2_155 N------------------LLRDELGAGPQTRVAVLLP-------AHWQT
MAB_3615|M.abscessus_ATCC_1997 N------------------MLRDEFGAGPGSTVAVRLP-------AHWQT
TH_4313|M.thermoresistible__bu GPPKPVPLLHSNVLDLIDRLLAKLRGGSRGSRGRAPMPNLVPLSLSLWAG
. :* . .. : :* : *
Mvan_1725|M.vanbaalenii_PYR-1 AAVLFGIWWIGAEAVLSG-DADIAMCTADRLADADASVG-----------
Mflv_4738|M.gilvum_PYR-GCK AAVLFGIWWIGAEVVLSG-EADIALCTADRIDDADAAAG-----------
Mb3296|M.bovis_AF2122/97 AAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNS----------
Rv3268|M.tuberculosis_H37Rv AAVLFGVWWIGAQAILDDSPADVALCTADRLAEADAVVNS----------
MMAR_1273|M.marinum_M AAVLFGVWWIGAEVVLDG-AADVALCTAGRLDEADSAVQD----------
MUL_2614|M.ulcerans_Agy99 AAVLFGVWWIGAEVVLDG-AADVALCTAGRLDEADSAVQD----------
MAV_4233|M.avium_104 AAVLFGVWWIGAEAVLAG-PADLALCTPPRLDEADAT-------------
MSMEG_1823|M.smegmatis_MC2_155 AAVLFGIWWIGAEIVLEG-PADIALCTRARLDEADDAVS-----------
MAB_3615|M.abscessus_ATCC_1997 AGVLLGIWWAGAELVFGDASTDVAFCTLG--DEPDAN-------------
TH_4313|M.thermoresistible__bu IYQVLFAFRAGSGVVLMDKFSPGEFAALVKRHQLRSTVLPPAALTMVLHD
:: : *: :: . : :.: :
Mvan_1725|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4738|M.gilvum_PYR-GCK --------------------------------------------------
Mb3296|M.bovis_AF2122/97 --------------------------------------------------
Rv3268|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1273|M.marinum_M --------------------------------------------------
MUL_2614|M.ulcerans_Agy99 --------------------------------------------------
MAV_4233|M.avium_104 --------------------------------------------------
MSMEG_1823|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3615|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4313|M.thermoresistible__bu ESVTDLSPLRIVRSITAPLSPVHARQFMDRFGVLVLNSYGQTELGGEVVG
Mvan_1725|M.vanbaalenii_PYR-1 -----SGEIAVLSLDPFGKPVPDLPVGLTDYATAVR--------------
Mflv_4738|M.gilvum_PYR-GCK -----MGEIAVLSLDPFGKPVADLPVGLTDYATAVR--------------
Mb3296|M.bovis_AF2122/97 --AAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVR--------------
Rv3268|M.tuberculosis_H37Rv --AAVAGEVAVLSLDPFGRPATGLPVGVTDYATAVR--------------
MMAR_1273|M.marinum_M --A--AGEVAVLSLDPFGRPAPDLPVGITDYATSVR--------------
MUL_2614|M.ulcerans_Agy99 --A--AGEVAVLSLDPFGRPAPDLPVGVTDYATSVR--------------
MAV_4233|M.avium_104 ----GAGEVAVLSLDPFGRPVSDPPIGVTDYATAVR--------------
MSMEG_1823|M.smegmatis_MC2_155 -----GGEVAVLSLDPFGKPAADLPVGVTDYATSVR--------------
MAB_3615|M.abscessus_ATCC_1997 -------EVCVLSLDAFGRPVPDLPLGLTDYATAVR--------------
TH_4313|M.thermoresistible__bu WTAADAREWGEAKLGSVGRPLPGIDVTIVDDEVLVRTPTTLARRIDPAFA
* .*...*:* .. : :.* . **
Mvan_1725|M.vanbaalenii_PYR-1 ------------------------VHGDQIVPERQPGPALEGRSADEVLA
Mflv_4738|M.gilvum_PYR-GCK ------------------------VHGDQIVPERSPSPALEGRSTDDVLA
Mb3296|M.bovis_AF2122/97 ------------------------VHGDQIVPEHNPGPVLAGRSVEQILR
Rv3268|M.tuberculosis_H37Rv ------------------------VHGDQIVPEHNPGPVLAGRSVEQILR
MMAR_1273|M.marinum_M ------------------------VHGDQISPERLPGPALAGRSVEQVLR
MUL_2614|M.ulcerans_Agy99 ------------------------VHGDQISPERLPGPALAGRSVEQVLR
MAV_4233|M.avium_104 ------------------------VHGDQIVPEPRPGPALNGRSVDQVLQ
MSMEG_1823|M.smegmatis_MC2_155 ------------------------VHGDQIVPERRPGPALAGQSVGEVLD
MAB_3615|M.abscessus_ATCC_1997 ------------------------VHGDRFTPAG-AGPAVDGRPVDEVAA
TH_4313|M.thermoresistible__bu DRLTDDGWFHTGDLGWLDEDGFLWLDGRVSDMINRGGLKVFPGTVEDVLV
:.* . : .. ::
Mvan_1725|M.vanbaalenii_PYR-1 AARASAASQGLTPADRVMSAARWD------------TADDVVDQLLALYA
Mflv_4738|M.gilvum_PYR-GCK AARASAAAQGLSGTDRVLSTAAWD------------TADDIVDRLLALYV
Mb3296|M.bovis_AF2122/97 DCAASAAARGLTAADRVLSTASWA------------GPDELVDGLLAILA
Rv3268|M.tuberculosis_H37Rv DCAASAAARGLTAADRVLSTASWA------------GPDELVDGLLAILA
MMAR_1273|M.marinum_M ECAESAAARHLTAADRVLSTGTWT------------SPGELVDHLLAILS
MUL_2614|M.ulcerans_Agy99 ECAESAAARHLTAADRVLSTGTWT------------SPGELVDHLLAILS
MAV_4233|M.avium_104 QCRSSAAARGLTAADRVLSSASWP------------DPDALVDGLLAILA
MSMEG_1823|M.smegmatis_MC2_155 AARSAAAASGFTADDRVLSTASWA------------TPHELIANLLAVFA
MAB_3615|M.abscessus_ATCC_1997 AARESAVAQGITGGDRVLSSGAWD------------SLEALISTLLAVLI
TH_4313|M.thermoresistible__bu AADGVREAAVVGVPDDRLGEVPWAFVVRAGERVTEEDLRAWCRERLTPYR
. : . * :. * *:
Mvan_1725|M.vanbaalenii_PYR-1 VGASLVLVANPDPALVERRRETEKLTRTTL-----
Mflv_4738|M.gilvum_PYR-GCK VGASLVQVANPDPASMARRADTEKITRATP-----
Mb3296|M.bovis_AF2122/97 AGASLVQVANPDPAMLQRRIATEKVTRVL------
Rv3268|M.tuberculosis_H37Rv AGASLVQVANPDPAMLQRRIATEKVTRVL------
MMAR_1273|M.marinum_M VGASLVQVANPDPAAMQRRIEMEKVSRVL------
MUL_2614|M.ulcerans_Agy99 VGASLVQVANPDPAAMQRRIEMEKVSRVL------
MAV_4233|M.avium_104 VGGSLVQVANADPAVRQRRIESEKVTRVL------
MSMEG_1823|M.smegmatis_MC2_155 AGASLVQVANPDPGAQERRRQTEKVTRG-------
MAB_3615|M.abscessus_ATCC_1997 TGASLVQVANPDTAAQERRVASEKVTKTLP-----
TH_4313|M.thermoresistible__bu IPARFVFVDELPRNEVGKVVKRDLAARAADLVQRT
. :* * : : : ::