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VSQSPVERVRPTASRIDCHNHHDLGGEGRRPIRGVALRKSWLVASAAVVLGASVPALTPAPAYAVCGSIS GVNVDVTGCADPLYELNAAPPPPPPPPPPPPPPPPPVYVPPPPPPVYVPPVYVPHVSVCADVGRRISVAG CV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1623 | - | - | 100% (142) | hypothetical protein Mvan_1623 |
| M. vanbaalenii PYR-1 | Mvan_5366 | - | 2e-12 | 67.57% (37) | hypothetical protein Mvan_5366 |
| M. vanbaalenii PYR-1 | Mvan_1068 | - | 5e-10 | 37.76% (98) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 2e-09 | 50.00% (58) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_4819 | - | 3e-42 | 59.71% (139) | hypothetical protein Mflv_4819 |
| M. tuberculosis H37Rv | Rv3876 | - | 2e-09 | 50.00% (58) | hypothetical protein Rv3876 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 6e-08 | 62.16% (37) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_1963 | - | 2e-11 | 40.00% (100) | MmpS family protein |
| M. marinum M | MMAR_2607 | - | 2e-11 | 35.16% (128) | hypothetical protein MMAR_2607 |
| M. avium 104 | MAV_3282 | - | 1e-09 | 57.14% (42) | hypothetical protein MAV_3282 |
| M. smegmatis MC2 155 | MSMEG_5916 | - | 3e-13 | 68.42% (38) | hypothetical protein MSMEG_5916 |
| M. thermoresistible (build 8) | TH_3058 | - | 1e-05 | 51.43% (35) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0202 | pra | 4e-10 | 63.41% (41) | proline-rich antigen Pra-like protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------MSGTDN
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------MGGALF
Mb3906|M.bovis_AF2122/97 MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
Rv3876|M.tuberculosis_H37Rv MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------MTDQPP
MUL_0202|M.ulcerans_Agy99 --------------------------------------------MTDQPP
Mvan_1623|M.vanbaalenii_PYR-1 ----------------------------------------MSQSPVER--
Mflv_4819|M.gilvum_PYR-GCK -------------------MRWLRILPAKAHCLLRPDAVQMSRGPASRAL
MMAR_2607|M.marinum_M ----------------------------------------MGSESNEA--
MAV_3282|M.avium_104 ----------------------------------------MTPTPSLQRR
MAB_1963|M.abscessus_ATCC_1997 PGSGNPGEVPDLDGPNEEAAAPDSSGADSAAFHSQAYSAPESEQFTSPYV
MSMEG_5916|M.smegmatis_MC2_155 AG---------------ATGAAALAGAQPAG-----DSAPMSVLGPVPAF
Mb3906|M.bovis_AF2122/97 PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
Rv3876|M.tuberculosis_H37Rv PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
TH_3058|M.thermoresistible__bu -----------VDVDVPTPPPIPAPPAIPAP--------PDVNVNVPPPP
MLBr_02395|M.leprae_Br4923 PSG---------SNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVG
MUL_0202|M.ulcerans_Agy99 PGG---------SYP-PPPPPPGSSGGSEPPAG----GYQAPPPPSAPSG
Mvan_1623|M.vanbaalenii_PYR-1 --------------VRPTASRIDCHNHHDLGGEGRRPIRGVALRKSWLVA
Mflv_4819|M.gilvum_PYR-GCK YSKSACRCAGTYWAVGPRAVRVGCHNHHSCLR-----ISGVALRGSVIVA
MMAR_2607|M.marinum_M -----------------LAKEISMSPWK----------RPSATAAIAALA
MAV_3282|M.avium_104 VTLVVLALLTVLLVVLGVTIDVTMGVLARRNLHDR-LLAATSRADALSAA
.
MAB_1963|M.abscessus_ATCC_1997 PYDEYETQLVDGEEPPPPRWPWVVGVAAIIAAITLVASVALLVAGRSDET
MSMEG_5916|M.smegmatis_MC2_155 P-------------PPPP--------------------------------
Mb3906|M.bovis_AF2122/97 PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
Rv3876|M.tuberculosis_H37Rv PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
TH_3058|M.thermoresistible__bu AIP------APPAIPAPPAVNIG---------------------------
MLBr_02395|M.leprae_Br4923 G----------SYPPPPPP-------------------------------
MUL_0202|M.ulcerans_Agy99 G----------GYPPPPPPPPPS---------------------------
Mvan_1623|M.vanbaalenii_PYR-1 SAAVVLGASVPALTPAPAYAVCGSISGVNVDVTG----------------
Mflv_4819|M.gilvum_PYR-GCK SAAMFV-AGALGVAPAGHAAVCGSVGGVHVDVSG----------------
MMAR_2607|M.marinum_M FTALPQVLAVMAPSGAAQADVCVNAG-RRVSVSG----------------
MAV_3282|M.avium_104 HTAPDLLAAELNGGGIRALVVTADGQAYGDRVIS----------------
MAB_1963|M.abscessus_ATCC_1997 NGAAKSSTVIPT------------------------PSTTPWNEIITTTT
MSMEG_5916|M.smegmatis_MC2_155 ------------------------------------PPPPFWG-------
Mb3906|M.bovis_AF2122/97 APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
Rv3876|M.tuberculosis_H37Rv APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 ---------------------------------GGSYPPPPPP----GGS
MUL_0202|M.ulcerans_Agy99 ---------------------------------TSGYPPPPPPPPLEGGY
Mvan_1623|M.vanbaalenii_PYR-1 ------------------------------------CADPLYELN---AA
Mflv_4819|M.gilvum_PYR-GCK ------------------------------------CADPLYELNDALAP
MMAR_2607|M.marinum_M ------------------------------------CAN----------I
MAV_3282|M.avium_104 ------------------------------------PDLAEGPVEPPPPY
MAB_1963|M.abscessus_ATCC_1997 PPPPPPPPPPTTEPPPPPPPPVVTET------------------------
MSMEG_5916|M.smegmatis_MC2_155 PPPPPPPPPPFWRPPPPPP-------------------------------
Mb3906|M.bovis_AF2122/97 PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
Rv3876|M.tuberculosis_H37Rv PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 YPPPPPSTGAYAPPPPGPAIRSLPKEA-----------------------
MUL_0202|M.ulcerans_Agy99 PPPPPPSAGGYAPPPPGPAIRALPAES-----------------------
Mvan_1623|M.vanbaalenii_PYR-1 PPPPPPPPPPPP--PPPPPVYVPPP-------------------------
Mflv_4819|M.gilvum_PYR-GCK PPPPPPPPPPPPGAPPPPPPPPPPP-------------------------
MMAR_2607|M.marinum_M ADAIAPYVPPPAEYAPLPEDYPPPP-------------------------
MAV_3282|M.avium_104 PPPLPPPYPPPAYPPPYPPPYPPPPGPL----------------------
MAB_1963|M.abscessus_ATCC_1997 --------------VTVEPPPPPPPPVTTHEAPPPVTTTTTPPPPPPPTT
MSMEG_5916|M.smegmatis_MC2_155 --------------IWLPPPPPPPP----FWGPP--------PPPRPP--
Mb3906|M.bovis_AF2122/97 ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
Rv3876|M.tuberculosis_H37Rv ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 ------------YTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACV
MUL_0202|M.ulcerans_Agy99 ------------YTPWITRVLAALIDFAPYVVVTGIGWLIMMVTTTPSCV
Mvan_1623|M.vanbaalenii_PYR-1 ----------------PPPVYVPPVYVPHVSVCADVGRRIS----VAGCV
Mflv_4819|M.gilvum_PYR-GCK ----------------PPPVYIPPP-LPNVNVCADVGRRIN----VSGCI
MMAR_2607|M.marinum_M ----------------PPP--------PNVNVCANVGRRIS----VSGCV
MAV_3282|M.avium_104 ------PDTTATAVVHPLSGGARLILVADTTQTTQVTRQLRGLMIAAGIV
MAB_1963|M.abscessus_ATCC_1997 TTPAGPRQITY---SVTGSKAPLDRISITWTDGSGRTRVNPNVYIPWSIT
MSMEG_5916|M.smegmatis_MC2_155 ----------------------------------GHWR------------
Mb3906|M.bovis_AF2122/97 NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
Rv3876|M.tuberculosis_H37Rv NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 TDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATGSSI
MUL_0202|M.ulcerans_Agy99 TDISQYDIGQYCVSQPSMIGQLAQWLLSLVGLAYLVWDYGYRQGTTGSSI
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 TLLIAALLLIAVSRAALRPLDRLTALANAITTGDRGRRLRPHRADTELGR
MAB_1963|M.abscessus_ATCC_1997 VTPISNSEIGSVSASS------------------FLRLSQLNCTITTSDG
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
Rv3876|M.tuberculosis_H37Rv RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 GKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKR
MUL_0202|M.ulcerans_Agy99 GKSIMKFKVVSETTGEPLGFGMSVVRQLAHIVDAVICYIGFLFPLWDAKR
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 AASAFDTMLDALEMSERRAQQAAEAAQRAETATRRFLVDAAHELRTPIAG
MAB_1963|M.abscessus_ATCC_1997 QVLSSNNNNSAQATC-----------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
Rv3876|M.tuberculosis_H37Rv YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 QTLADKIMTTVCLPI-----------------------------------
MUL_0202|M.ulcerans_Agy99 QTLADKIMTTVCLPL-----------------------------------
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 MQVAAEQLAHGASEHPDDGQYRRAGLLLSDARRAGRLVNDMLDLSRIDAG
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
Rv3876|M.tuberculosis_H37Rv ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 LPLELHDVDVAAVLRDEADRAALLAPQIGVRRTGLTALNVRADATRLSQI
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
Rv3876|M.tuberculosis_H37Rv VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 VSNLLDN-ARRYTPAGGAIEIDLRAGDGAAEITVTDTGPGIPDDEREHIF
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
Rv3876|M.tuberculosis_H37Rv STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 DRLVRLDAGRARDHGGAGLGLAIARALARAHGGDLVCLPHQGGARFRLTL
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
Rv3876|M.tuberculosis_H37Rv PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
TH_3058|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MUL_0202|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1623|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2607|M.marinum_M --------------------------------------------------
MAV_3282|M.avium_104 PRATTQ--------------------------------------------
MAB_1963|M.abscessus_ATCC_1997 ----------------
MSMEG_5916|M.smegmatis_MC2_155 ----------------
Mb3906|M.bovis_AF2122/97 ELAAALSDDFERAGRR
Rv3876|M.tuberculosis_H37Rv ELAAALSDDFERAGRR
TH_3058|M.thermoresistible__bu ----------------
MLBr_02395|M.leprae_Br4923 ----------------
MUL_0202|M.ulcerans_Agy99 ----------------
Mvan_1623|M.vanbaalenii_PYR-1 ----------------
Mflv_4819|M.gilvum_PYR-GCK ----------------
MMAR_2607|M.marinum_M ----------------
MAV_3282|M.avium_104 ----------------