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M. vanbaalenii PYR-1 Mvan_1489 (-)

annotation: O-sialoglycoprotein endopeptidase
coordinates: 1579844 - 1580866
length: 340

MIILAVESSCDETGVGIAELGDDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALATA
GVSKPDVVAATIGPGLAGALLVGVAAAKAYSAAWQVPFYAVNHLGGHLAADVFDHGPLPESIGLLVSGGH
THLLHVRSLGEPIVELGSTVDDAAGEAYDKIARLLGLGYPGGRVLDELAREGDPAAITFPRGMTGPRDDP
YAFSFSGLKTAVARYVESHPEASQADVAAGFQEAVADVLTAKAVRAAKDLGVSTLLIAGGVAANSRLREL
AGQRCADAGMTLRIPRPRLCTDNGAMIASFAAHLIAAGARPSPLDAASDPGLPVVQGQVA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1489--100% (340)O-sialoglycoprotein endopeptidase
M. vanbaalenii PYR-1Mvan_1487-3e-0631.20% (125) peptidase M22, glycoprotease
M. vanbaalenii PYR-1Mvan_2359-8e-0631.29% (163) (NiFe) hydrogenase maturation protein HypF

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3453cgcp1e-16183.82% (340) putative DNA-binding/iron metalloprotein/AP endonuclease
M. gilvum PYR-GCKMflv_4929-0.096.47% (340) O-sialoglycoprotein endopeptidase
M. tuberculosis H37RvRv3419cgcp1e-16183.82% (340) putative DNA-binding/iron metalloprotein/AP endonuclease
M. leprae Br4923MLBr_00379gcp1e-15884.16% (341) putative DNA-binding/iron metalloprotein/AP endonuclease
M. abscessus ATCC 19977MAB_3734c-1e-15279.77% (341) putative DNA-binding/iron metalloprotein/AP endonuclease
M. marinum MMMAR_1124gcp1e-16584.91% (338) O-sialoglycoprotein endopeptidase Gcp (glycoprotease)
M. avium 104MAV_4367-1e-16787.28% (338) O-sialoglycoprotein endopeptidase
M. smegmatis MC2 155MSMEG_1580-1e-17690.29% (340) O-sialoglycoprotein endopeptidase
M. thermoresistible (build 8)TH_1689gcp1e-17690.27% (339) PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE GCP
M. ulcerans Agy99MUL_0884gcp1e-16484.91% (338) putative DNA-binding/iron metalloprotein/AP endonuclease

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_1489|M.vanbaalenii_PYR-1       --------MIILAVESSCDETGVGIAELGDDGTVTLLADEVASSVDEHAR
Mflv_4929|M.gilvum_PYR-GCK          --------MIILAIESSCDETGVGIAELGDDGSVTLLADEVASSVDEHAR
TH_1689|M.thermoresistible__bu      --------MIILAIESSCDETGVGIAELAPDGSVTLLADEVASSVDEHAR
MSMEG_1580|M.smegmatis_MC2_155      --------MIILAIESSCDETGVGIADLRDDGTVTLLADEVASSVDEHAR
MMAR_1124|M.marinum_M               -----MPGTVILAIETSCDETGVGITRLEADGTLTLLADEVASSVDEHVR
MUL_0884|M.ulcerans_Agy99           -----MPGTIILAIETSCDETGVGITRLEADGTLTLLADEVASSVDEHVR
Mb3453c|M.bovis_AF2122/97           -------MTTVLGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVR
Rv3419c|M.tuberculosis_H37Rv        -------MTTVLGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVR
MLBr_00379|M.leprae_Br4923          MTISAVPGTIILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQAR
MAV_4367|M.avium_104                -------MTTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVR
MAB_3734c|M.abscessus_ATCC_199      -------MTVILAIESSCDETGVGIAELTPDGSVVLLADEVASSVEEHAR
                                              :*.:*:*********: *   *::.**********:*:.*

Mvan_1489|M.vanbaalenii_PYR-1       FGGVVPEIASRAHLEALGPTMRRALATAGVS---KPDVVAATIGPGLAGA
Mflv_4929|M.gilvum_PYR-GCK          FGGVVPEIASRAHLEALGPTMRRALATAGVD---KPDVVAATIGPGLAGA
TH_1689|M.thermoresistible__bu      FGGVVPEIASRAHLEALQPTMRRALAAAGVR---RPDVVAATIGPGLAGA
MSMEG_1580|M.smegmatis_MC2_155      FGGVVPEIASRAHLEALGPTMRRALDAAGIE---RPDVVAATIGPGLAGA
MMAR_1124|M.marinum_M               FGGVVPEIASRAHLEALGPAMRRALTTAGIV---RPDVVATTIGPGLAGA
MUL_0884|M.ulcerans_Agy99           FGGVVPEIASRAHLEALGPAMRRALTTAGIV---RPDVVATTIGPGLAGA
Mb3453c|M.bovis_AF2122/97           FGGVVPEIASRAHLEALGPAMRRALAAAGLK---QPDIVAATIGPGLAGA
Rv3419c|M.tuberculosis_H37Rv        FGGVVPEIASRAHLEALGPAMRRALAAAGLK---QPDIVAATIGPGLAGA
MLBr_00379|M.leprae_Br4923          FGGVVPEIASRAHLEALGPTIRCALAAAGLTGSAKPDVVAATIGPGLAGA
MAV_4367|M.avium_104                FGGVVPEIASRAHLEALGPTMRRALSAAGVT---KPDVVAATIGPGLAGA
MAB_3734c|M.abscessus_ATCC_199      FGGVVPEIASRAHLEALGVTARRALDLAGVQ---RPDVVAATIGPGLAGA
                                    *****************  : * **  **:    :**:**:*********

Mvan_1489|M.vanbaalenii_PYR-1       LLVGVAAAKAYSAAWQVPFYAVNHLGGHLAADVFDHGPLPESIGLLVSGG
Mflv_4929|M.gilvum_PYR-GCK          LLVGVAAAKAYAAAWQVPFYAVNHLGGHLAADVFDHGPLPESIGLLVSGG
TH_1689|M.thermoresistible__bu      LLVGVAAAKAYAAAWQVPFYAVNHLGGHLAADVYEHGPLPESVGLLVSGG
MSMEG_1580|M.smegmatis_MC2_155      LLVGVAAAKAYAAGWGVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGG
MMAR_1124|M.marinum_M               LLVGVAAAKAYAAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGG
MUL_0884|M.ulcerans_Agy99           LLVGVAAAKAYAAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGG
Mb3453c|M.bovis_AF2122/97           LLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGG
Rv3419c|M.tuberculosis_H37Rv        LLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGG
MLBr_00379|M.leprae_Br4923          LLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGG
MAV_4367|M.avium_104                LLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYQHGPLPECVALLVSGG
MAB_3734c|M.abscessus_ATCC_199      LLVGVSAAKGLALAWGVPFYGVNHLGGHIAADVYENGPLPECVALLVSGG
                                    *****:***. : .* ****.*******:****:::*****.:.******

Mvan_1489|M.vanbaalenii_PYR-1       HTHLLHVRSLGEPIVELGSTVDDAAGEAYDKIARLLGLGYPGGRVLDELA
Mflv_4929|M.gilvum_PYR-GCK          HTHLLHVRSLGEPIIELGSTVDDAAGEAYDKIARLLGLGYPGGRVLDELA
TH_1689|M.thermoresistible__bu      HTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGRVLDELA
MSMEG_1580|M.smegmatis_MC2_155      HTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGRVLDELA
MMAR_1124|M.marinum_M               HTHLLHVRSLGEPMVELGATVDDAAGEAYDKVARLLGLGYPGGKVLDDLA
MUL_0884|M.ulcerans_Agy99           HTHLLHVRSLGEPMVELGATVDDAAGEAYDKVARLLGLGYPGGKVLDDLA
Mb3453c|M.bovis_AF2122/97           HTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKALDDLA
Rv3419c|M.tuberculosis_H37Rv        HTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKALDDLA
MLBr_00379|M.leprae_Br4923          HTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLGYPGGKVLDDLA
MAV_4367|M.avium_104                HTHLLQVRSLGDPIVELGSTVDDAAGEAYDKVARLLGLGYPGGRVLDELA
MAB_3734c|M.abscessus_ATCC_199      HTSLLHVRSLAEPIEELGATVDDAAGEAYDKVARLLGLGYPGGKVLDELA
                                    ** **:****. *: ***:************:***********:.**:**

Mvan_1489|M.vanbaalenii_PYR-1       REGDPAAITFPRGMTGPRDDPYAFSFSGLKTAVARYVESH---PEASQAD
Mflv_4929|M.gilvum_PYR-GCK          REGDPKAITFPRGMTGPRDEPYAFSFSGLKTAVARYVESH---PEASQAD
TH_1689|M.thermoresistible__bu      RQGDSTAITFPRGMTGPRDAPYSFSFSGLKTAVARYVESH---PDAAPAD
MSMEG_1580|M.smegmatis_MC2_155      RTGDRDAIVFPRGMTGPRDDPYTFSFSGLKTAVARYVEAH---PEASHAD
MMAR_1124|M.marinum_M               RSGDPDAIVFPRGMTGPSDDPCAFSFSGLKTAVARYVEAH---PDFRPAD
MUL_0884|M.ulcerans_Agy99           RSGDPDAIVFPRGMTGPSDDPCAFSFSGLKTAVACYVEAH---PDFRPAD
Mb3453c|M.bovis_AF2122/97           RTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTAD
Rv3419c|M.tuberculosis_H37Rv        RTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTAD
MLBr_00379|M.leprae_Br4923          RTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESH---PDALPAD
MAV_4367|M.avium_104                RTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESH---PDAVNAD
MAB_3734c|M.abscessus_ATCC_199      QQGDSSAVPFPRGMTGPRDARHSFSFSGLKTAVARYLEKHGVEADFSPAD
                                    : **  *: *****:** *   :*********** *:* *   .    **

Mvan_1489|M.vanbaalenii_PYR-1       VAAGFQEAVADVLTAKAVRAAKDLGVSTLLIAGGVAANSRLRELAGQRCA
Mflv_4929|M.gilvum_PYR-GCK          VAAGFQEAVADVLTAKAVRAAGDLGVSTLLIAGGVAANSRLRELAAQRCE
TH_1689|M.thermoresistible__bu      IAAGFQEAVADVLTAKAVRACTDLGVSTLLIAGGVAANSRLRELAAERCA
MSMEG_1580|M.smegmatis_MC2_155      VAAGFQESVADVLTAKAVRAATDLGVSTLLIAGGVAANSRLRELAEERCA
MMAR_1124|M.marinum_M               VAAGFQEAVADVLTRKAVRAATGLGVSTLLIAGGVAANSRLRELATQRCS
MUL_0884|M.ulcerans_Agy99           VAAGFQEAVADVLTRKAVRAATGLGVSTLLIAGGVAANSRLRELATQRCS
Mb3453c|M.bovis_AF2122/97           IAAGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCG
Rv3419c|M.tuberculosis_H37Rv        IAAGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCG
MLBr_00379|M.leprae_Br4923          VAAGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSRLRELAAQRCA
MAV_4367|M.avium_104                VAAGFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCA
MAB_3734c|M.abscessus_ATCC_199      VAAGFQEAVADVLTMKAVRAATDLGVSTLLIAGGVAANSRVRALAEQRCA
                                    :******:****** *****.  ***:****.********:* ** :** 

Mvan_1489|M.vanbaalenii_PYR-1       DAGMTLRIPRPRLCTDNGAMIASFAAHLIAAGARPSPLDAASDPGLPVVQ
Mflv_4929|M.gilvum_PYR-GCK          AAGMTLRIPRPRLCTDNGAMIASFAAHLIAAGAAPSPLDAASDPGLPVVQ
TH_1689|M.thermoresistible__bu      EAALTLRIPRPRLCTDNGAMIASYAAHLIAAGAAPSPLDCASDPGLPVVQ
MSMEG_1580|M.smegmatis_MC2_155      AAGLTLRVPRPRLCTDNGAMIASFAAHLIAAGAQPSPLDAASDPGLPVVK
MMAR_1124|M.marinum_M               EAGLTLRIPRPRLCTDNGAMIAAFAAHLVAAKAAPSPLDVPSDPGLPVVK
MUL_0884|M.ulcerans_Agy99           EAGLTLRIPRPRLCTDNGAMIAAFAAHLVAAKAAPSPLDVPSDPGLPVVK
Mb3453c|M.bovis_AF2122/97           EAGRTLRIPSPRLCTDNGAMIAAFAAQLVAAGAPPSPLDVPSDPGLPVMQ
Rv3419c|M.tuberculosis_H37Rv        EAGRTLRIPSPRLCTDNGAMIAAFAAQLVAAGAPPSPLDVPSDPGLPVMQ
MLBr_00379|M.leprae_Br4923          AAGLMLRIPGPRFCTDNGAMIAAFAAHLLAAAAPPSPLDVPSDPGLPVVK
MAV_4367|M.avium_104                AAGLTLRIPRPGLCTDNGAMIASFAAHLVAAGAPPSPLDVPTDPGLPVVK
MAB_3734c|M.abscessus_ATCC_199      ETGLTLRVPPLRLCTDNGAMIASFAAHLVAAGAQPSSLQAAADPGLPVVK
                                     :.  **:*   :*********::**:*:** * **.*: .:******::

Mvan_1489|M.vanbaalenii_PYR-1       GQVA
Mflv_4929|M.gilvum_PYR-GCK          GQVA
TH_1689|M.thermoresistible__bu      GQVV
MSMEG_1580|M.smegmatis_MC2_155      GQVA
MMAR_1124|M.marinum_M               GQVG
MUL_0884|M.ulcerans_Agy99           GQVG
Mb3453c|M.bovis_AF2122/97           GQVR
Rv3419c|M.tuberculosis_H37Rv        GQVR
MLBr_00379|M.leprae_Br4923          RQIN
MAV_4367|M.avium_104                AQVS
MAB_3734c|M.abscessus_ATCC_199      GQVH
                                     *: