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RIVIALGGNAILRRGQPMTADNQRENIRSAAQSIATVAEGNQLVIAHGNGPQVGLLALQAASYHDVAPYP LDVLGAQTEAMIGYVIEQELGNVLPPEQPLATVLTMIEVAPADPAFANPTKPIGPVYDRQTADAMHAASG WTFAPDGEHFRRVIASPKPKRIFEIGPIRTLVEHGTMVICAGGGGIPTVYDGQGRLQGVEAVIDKDLASA LLAEQLHADMLVIATDVDGVYTGWGTPDQRRLSRITPDELETMHFAAGSMGPKVEAACRFVRNTGRPASI GALGDIARIAAGQAGTRVAQSSEGSPPEERCCT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1389 | - | - | 100% (314) | carbamate kinase |
| M. vanbaalenii PYR-1 | Mvan_3312 | - | 3e-08 | 26.54% (309) | acetylglutamate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1682 | argB | 2e-07 | 25.90% (278) | acetylglutamate kinase |
| M. gilvum PYR-GCK | Mflv_3528 | - | 3e-07 | 26.47% (272) | acetylglutamate kinase |
| M. tuberculosis H37Rv | Rv1654 | argB | 2e-07 | 25.90% (278) | acetylglutamate kinase |
| M. leprae Br4923 | MLBr_01408 | argB | 4e-05 | 34.88% (86) | acetylglutamate kinase |
| M. abscessus ATCC 19977 | MAB_2338 | - | 2e-06 | 35.56% (90) | acetylglutamate kinase |
| M. marinum M | MMAR_2464 | argB | 2e-06 | 26.79% (280) | acetylglutamate kinase ArgB |
| M. avium 104 | MAV_3116 | argB | 9e-07 | 25.87% (286) | acetylglutamate kinase |
| M. smegmatis MC2 155 | MSMEG_3774 | argB | 3e-08 | 27.18% (287) | acetylglutamate kinase |
| M. thermoresistible (build 8) | TH_1595 | argB | 2e-08 | 28.62% (283) | Probable Acetylglutamate kinase argB |
| M. ulcerans Agy99 | MUL_1646 | argB | 4e-06 | 26.43% (280) | acetylglutamate kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2464|M.marinum_M ----MTI--------ETLSTQSKAQVLAEALPWLKQLHGRVVVIKYGG--
MUL_1646|M.ulcerans_Agy99 ----MTI--------ETLSTQSKAQVLAEALRWLKQLHGRVVVIKYGG--
MLBr_01408|M.leprae_Br4923 ----MTVLMNRTGDDETLSTQVKAEVLAEALPWLKQLHGKVVVVKYSG--
MAV_3116|M.avium_104 ----MTP------STEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGG--
Mb1682|M.bovis_AF2122/97 ----MSR-------IEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGG--
Rv1654|M.tuberculosis_H37Rv ----MSR-------IEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGG--
MSMEG_3774|M.smegmatis_MC2_155 ----MST--------PSIDRGFKADVLASALPWLKQLHGKIVVVKYGG--
TH_1595|M.thermoresistible__bu MSDVVEP--------LMVDRKVKASVLSAALPWLKQLHGKIVVVKYGG--
Mflv_3528|M.gilvum_PYR-GCK ---------------MSLTTPDKAQVLADALPWLTALNGKIVVVKYGG--
MAB_2338|M.abscessus_ATCC_1997 MKA-------------TKKATKKAAVLAGALPWLKKLHGTIVVIKYGG--
Mvan_1389|M.vanbaalenii_PYR-1 MRIVIALG------GNAILRRGQPMTADNQRENIRSAAQSIATVAEGNQL
:. . : :..: ..
MMAR_2464|M.marinum_M -NAMTDDTLRQAFAADMAFLRNCGIHPVVVHGGGPQITAMLGKLGIEGDF
MUL_1646|M.ulcerans_Agy99 -NAMTDDTLRQAFAADMAFLRNCGIHPVVVHGGGPQITAMLGKLGIEGDF
MLBr_01408|M.leprae_Br4923 -NAMTDDMLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIADDF
MAV_3116|M.avium_104 -NAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIPGDF
Mb1682|M.bovis_AF2122/97 -NAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDF
Rv1654|M.tuberculosis_H37Rv -NAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDF
MSMEG_3774|M.smegmatis_MC2_155 -NAMTDDVLKAAFAADMVFLRNCGIHPVVVHGGGPQISAMLKRLGIEGDF
TH_1595|M.thermoresistible__bu -NAMTDDTLREAFAEDMVFLRNCGIYPVVVHGGGPQISAMLQRLGIEGDF
Mflv_3528|M.gilvum_PYR-GCK -NAMTDDRLKAAFAADMVFLRNCGIHPVVVHGGGPQISAMLKKLGIAGDF
MAB_2338|M.abscessus_ATCC_1997 -NAMTDDALKNAFAEDMVFLRNCGIHPVVVHGGGPQISAMLKKLGVDGEF
Mvan_1389|M.vanbaalenii_PYR-1 VIAHGNGPQVGLLALQAASYHDVAPYPLDVLG--AQTEAMIG--YVIEQE
* :. :* : . :: . :*: * * .* **: : :
MMAR_2464|M.marinum_M KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGVTGEDAQLFT
MUL_1646|M.ulcerans_Agy99 KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGVTGEDAQLFT
MLBr_01408|M.leprae_Br4923 KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFT
MAV_3116|M.avium_104 KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFT
Mb1682|M.bovis_AF2122/97 KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFT
Rv1654|M.tuberculosis_H37Rv KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFT
MSMEG_3774|M.smegmatis_MC2_155 KGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGVTGEDAQLFT
TH_1595|M.thermoresistible__bu KGGFRVTTPEVLDVARMVLFGQVGRQLVNLINAHGPYAVGITGEDAQLFT
Mflv_3528|M.gilvum_PYR-GCK KGGFRVTTPEVLEVARMVLFGQVGRELVNLINAYGPYAVGITGEDAHLFT
MAB_2338|M.abscessus_ATCC_1997 KGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGPYAVGITGEDAQLFT
Mvan_1389|M.vanbaalenii_PYR-1 LGNVLPPEQPLATVLTMIEVAPADPAFANPTKPIGPVYDRQTADAMHAAS
*.. . : : *: .. .. :.. :. ** *.: : :
MMAR_2464|M.marinum_M --------AVRRSVNVDGVATDIGLVGDVDHVNAAALMDLIAAHR-IPVI
MUL_1646|M.ulcerans_Agy99 --------AVRRSVNVDGVATDIGLVGDVDHVNAAALMDLIAAHR-IPVI
MLBr_01408|M.leprae_Br4923 --------AGRRSATVDGMATDIGLVGDVDQVNIAAVLDLISAHR-IPVV
MAV_3116|M.avium_104 --------AVRRSVTVDGVTTDIGLVGDVERVNAAAVLDLIAARR-IPVV
Mb1682|M.bovis_AF2122/97 --------AVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGR-IPVV
Rv1654|M.tuberculosis_H37Rv --------AVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGR-IPVV
MSMEG_3774|M.smegmatis_MC2_155 --------AVRRNVTVDGVATDIGLVGDVEHVNAGSLLDLIAAGR-IPVV
TH_1595|M.thermoresistible__bu --------AVRRSVTVDGVATDIGLVGDVEKVSTDAVLDLIGAGR-IPVV
Mflv_3528|M.gilvum_PYR-GCK --------AVRRTVMVDGVATDIGLVGDVERVNTDAVLDLIDAGR-IPVV
MAB_2338|M.abscessus_ATCC_1997 --------AVRRTATVDGVETDIGLVGDVAQVSPEAILDLIDAGR-IPVV
Mvan_1389|M.vanbaalenii_PYR-1 GWTFAPDGEHFRRVIASPKPKRIFEIGPIRTLVEHGTMVICAGGGGIPTV
* . .. . * :* : : . : : . **.:
MMAR_2464|M.marinum_M STLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPERDS
MUL_1646|M.ulcerans_Agy99 STLAPDAEGVVHNINADTAAAAVAEALGAEKLLMLTDVEGLYTSWPDRDS
MLBr_01408|M.leprae_Br4923 STLAPDRDGVVHNINADTAAAALAETLGAEKLLMLTNVEGLYTRWPERDS
MAV_3116|M.avium_104 STLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDS
Mb1682|M.bovis_AF2122/97 STLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDS
Rv1654|M.tuberculosis_H37Rv STLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDS
MSMEG_3774|M.smegmatis_MC2_155 STIAPDADGVVHNINADTAAAALAEALGAEKLVMLTDVEGLYTDWPDRTS
TH_1595|M.thermoresistible__bu SSLAPDTDGVVYNINADTAAAALAAALRAEKLVMLTDIEGLYTDWPNRES
Mflv_3528|M.gilvum_PYR-GCK STIAPDTAGLVYNINADTAAAALAEALGAEKLLMLTDVEGLYTDWPDRGS
MAB_2338|M.abscessus_ATCC_1997 STVAPDADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRES
Mvan_1389|M.vanbaalenii_PYR-1 YDGQGRLQGVEAVIDKDLASALLAEQLHADMLVIATDVDGVYTGWGTPDQ
*: :: * *:. :* * *: *:: *:::*:** * .
MMAR_2464|M.marinum_M -LVREIDTAALEQLLPRLEAGMIPKVEACLRAVTG-GVPSAHVIDGRVEH
MUL_1646|M.ulcerans_Agy99 -LVREIDTAALEQLLPRLEAGMIPKVEGCLRAVTG-GVPSAHVIDGRVEH
MLBr_01408|M.leprae_Br4923 -LVNEIDSAALAQLLPTLEAGMIPKVEACLRAVTG-GVPSAHVIDGRVKH
MAV_3116|M.avium_104 -LVSEIDTATLSQLLPTLEAGMIPKVEACLRAVSA-GVPSAHVIDGRVEH
Mb1682|M.bovis_AF2122/97 -LVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIG-GVPSAHIIDGRVTH
Rv1654|M.tuberculosis_H37Rv -LVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIG-GVPSAHIIDGRVTH
MSMEG_3774|M.smegmatis_MC2_155 -LVSEIDTGALTQLLPKLESGMVPKIEACLRAVNG-GVPSAHVIDGRVEH
TH_1595|M.thermoresistible__bu -LVSEIDTAELEKLLPGLESGMVPKIEACLRAVNG-GVPSAHVIDGRVEH
Mflv_3528|M.gilvum_PYR-GCK -LVNQINSDALAELLPTLEEGMVPKIEACLRAIDG-GVPSAHVIDGRVEH
MAB_2338|M.abscessus_ATCC_1997 -LVTEIAAEDLRSLLPKLESGMIPKIEACLRAVDG-GVPSAHIIDGRVEH
Mvan_1389|M.vanbaalenii_PYR-1 RRLSRITPDELETMHFAAGS-MGPKVEAACRFVRNTGRPASIGALGDIAR
: .* . * : * **:*.. * : * *:: * : :
MMAR_2464|M.marinum_M CVLVELFTNAGTGTKVVSA------
MUL_1646|M.ulcerans_Agy99 CVLVELFTNAGTGTKVVSA------
MLBr_01408|M.leprae_Br4923 CVLVELLTNEGTGTKVVSA------
MAV_3116|M.avium_104 CVLVELFTDAGTGTKVVSS------
Mb1682|M.bovis_AF2122/97 CVLVELFTDAGTGTKVVRG------
Rv1654|M.tuberculosis_H37Rv CVLVELFTDAGTGTKVVRG------
MSMEG_3774|M.smegmatis_MC2_155 CVLVELFTDEGTGTKVVAQ------
TH_1595|M.thermoresistible__bu CVLVELFTDEGTGTKVVSA------
Mflv_3528|M.gilvum_PYR-GCK CVLVELFTNEGAGTKVVRS------
MAB_2338|M.abscessus_ATCC_1997 CVLVELFTDEGVGTIIRSKS-----
Mvan_1389|M.vanbaalenii_PYR-1 IAAGQAGTRVAQSSEGSPPEERCCT
. : * . .: