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M. vanbaalenii PYR-1 Mvan_1221 (-)

TPPNTTTSTRVDLALLGIRGRPPVSRTAGAGPSDDGHLVIDGLNAALPRNPQSPFAFDGDRILYDGHDTG
LDVEVIERPKFYDLTTVDGVRYEQLARLHGRNVLATTVVQTCIRYSPDQRCRFCSIEESLRAGATTAVKR
PAELAEVARAAVRLDGVTQMVMTTGTSAGTDRGARHLARCVRAVKAAVPQLPIQVQCEPPAELGVLAELH
EAGADAIGIHVESLDDDVRRRWMPGKATVPLAQYRAAWREAVKVFGRNQVSTYLLVGLGEDPGELVAGAA
ELIKMGVYPFVVPFRPHPGTLAVDVDGATAPDATVVEKVSREIAGLLRSAGMAGTDQKAGCAACGACGVL
QSLGG*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_1221	-	-	100% (356)	radical SAM domain-containing protein
M. vanbaalenii PYR-1	Mvan_6000	-	3e-05	27.68% (112)	radical SAM domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb0893c	moaA	8e-05	29.50% (139)	molybdenum cofactor biosynthesis protein A
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	Rv0869c	moaA	8e-05	29.50% (139)	molybdenum cofactor biosynthesis protein A
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_0568	-	1e-170	85.01% (347)	radical SAM domain-containing protein
M. thermoresistible (build 8)	TH_1071	moaA	6e-05	25.26% (190)	molybdenum cofactor biosynthesis protein A
M. ulcerans Agy99	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


Mb0893c|M.bovis_AF2122/97           --------MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLR
Rv0869c|M.tuberculosis_H37Rv        --------MTLTALGMPALRSRTNGIADPRVVPTTGPLVDTFGRVANDLR
TH_1071|M.thermoresistible__bu      --------MTVTALGLPAVRRPS----PPSAPPASGPLVDTFGRVHTDLR
Mvan_1221|M.vanbaalenii_PYR-1       MTPPNTTTSTRVDLALLGIRGRP----PVSRTAGAGPSDDGH-LVIDGLN
MSMEG_0568|M.smegmatis_MC2_155      -------MSTRVDLALLGFRGRP----PVHRNAGAGPSADGH-LVIDGLN
                                             * . *.: ..*  .         . :**  * .  *  .*.

Mb0893c|M.bovis_AF2122/97           VSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLG----
Rv0869c|M.tuberculosis_H37Rv        VSLTDRCNLRCSYCMPERGLRWLPGEQLLRPDELARLIHIAVTRLG----
TH_1071|M.thermoresistible__bu      ISLTDRCNLRCTYCMPAEGLDWLPGEHLLRPDELARLLHIAVTRLG----
Mvan_1221|M.vanbaalenii_PYR-1       AALPR--NPQSPFAFDGDRILYDGHDTGLDVEVIERPKFYDLTTVDGVRY
MSMEG_0568|M.smegmatis_MC2_155      AAIPR--NPLSPFVFDGTRVLLDGEDTGLDVEVIDRPRFYDLTTGDGVPY
                                     ::.   *  ..: :    :     :  *  : : *  .  :*  .    

Mb0893c|M.bovis_AF2122/97           VTSVRFTGGEPLLAHHLDEVVAATARLRPR---PEISLTTNGVGLARRAG
Rv0869c|M.tuberculosis_H37Rv        VTSVRFTGGEPLLAHHLDEVVAATARLRPR---PEISLTTNGVGLARRAG
TH_1071|M.thermoresistible__bu      ITNVRFTGGEPLVARHLEEVVAAAAAERPR---PEIALTTNGIGLAKRAR
Mvan_1221|M.vanbaalenii_PYR-1       EQLARLHGRNVLATTVVQTCIRYSPDQRCRFCSIEESLRAGATTAVKRPA
MSMEG_0568|M.smegmatis_MC2_155      EKLARLHGRNVLATTVVQTCIRYSPDQRCRFCTIEESLRSGATTAVKRPA
                                       .*: * : * :  ::  :  :.  * *    * :* :..   .:*. 

Mb0893c|M.bovis_AF2122/97           ALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVK
Rv0869c|M.tuberculosis_H37Rv        ALAEAGLDRVNVSLDSIDRAHFAAITRRDRLAHVLAGLAAAKAAGLTPVK
TH_1071|M.thermoresistible__bu      RLKDAGLDRVNVSLDTVDPVRFARITRRDRLADVLAGLEAARAAGLTPVK
Mvan_1221|M.vanbaalenii_PYR-1       ELAEVARAAVRLDGVTQMVMTTGTSAGTDRGARHLARCVRAVKAAVPQLP
MSMEG_0568|M.smegmatis_MC2_155      ELAEVAAAAVRLDGVTQMVMTTGTSAGTDRGARHLARCVRAVKAAVPALP
                                     * :..   *.:.  :      .  :  ** *  **    *  *.:. : 

Mb0893c|M.bovis_AF2122/97           VNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSA
Rv0869c|M.tuberculosis_H37Rv        VNAVLDPTTGREDVVDLLRFCLERGYQLRVIEQMPLDAGHSWRRNIALSA
TH_1071|M.thermoresistible__bu      VNAVLDAETGLDDAVQLLRFCLDRGYQLRIIEQMPLDAGHQWRRDQTLSA
Mvan_1221|M.vanbaalenii_PYR-1       IQVQCEPPAELGVLAELH----EAGADAIGIHVESLDD-DVRRRWMPGKA
MSMEG_0568|M.smegmatis_MC2_155      IQVQCEPPADLAVLSELR----AAGADAIGIHVESLDD-EVRSRWMPGKA
                                    ::.  :. :      :*       * :   *.  .**  .   *  . .*

Mb0893c|M.bovis_AF2122/97           DDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHA
Rv0869c|M.tuberculosis_H37Rv        DDVLAALRPHFRLRPDPAPRGSAPAELWLVDAGPNTPRGRFGVIASVSHA
TH_1071|M.thermoresistible__bu      DEVLAALQREFRLSPDPTPRGSAPAQLWRIDG----TGATVGIIATVSHA
Mvan_1221|M.vanbaalenii_PYR-1       TVPLAQYRAAWREAVKVFGRN--QVSTYLLVGLGEDPGELVAGAAELIKM
MSMEG_0568|M.smegmatis_MC2_155      TVALDAYRAAWREAVRVFGRN--QVSTYLLVGLGENPDELVAGAGELIDM
                                       *   :  :*       *.   .. : : .    .   ..  . : . 

Mb0893c|M.bovis_AF2122/97           FCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMW
Rv0869c|M.tuberculosis_H37Rv        FCSTCDRTRLTADGQIRSCLFSTEETDLRRLLRGGADDDAIEAAWRAAMW
TH_1071|M.thermoresistible__bu      FCSACDRTRLTADGQVRNCLFAQQETDLRGLLRSGADDDAVEAAWRAAMW
Mvan_1221|M.vanbaalenii_PYR-1       GVYPFVVPFRPHPGTLAVDVDGATAPDATVVEKVSREIAGLLRSAGMAGT
MSMEG_0568|M.smegmatis_MC2_155      GVYPFVVPFRPQSGSLATDVDGAIAPDSGLVEKVSRAVADLLRQAGMSGA
                                       .   .  .  * :   : .   .*   : : .     :      :  

Mb0893c|M.bovis_AF2122/97           SKPAGHGINAPDFIQPDRPMSAIGG
Rv0869c|M.tuberculosis_H37Rv        SKPAGHGINAPDFIQPDRPMSAIGG
TH_1071|M.thermoresistible__bu      AKAAGHGINDPDFVQPARPMSAIGG
Mvan_1221|M.vanbaalenii_PYR-1       DQKAGCAACG-----ACGVLQSLGG
MSMEG_0568|M.smegmatis_MC2_155      DQRAGCAACG-----ACSVLQNLGA
                                     : ** .        .   :. :*.