For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDVINPTSTESVEVNGVKVGPTGQTRSGMTADALRAAVSDHLVYSIARPAAVLTPEHYYRALSLAVRDRM QKRWMATTQDWLDLSAKVTCYLSAEFLMGPQLGNNLLNLGIEDEAREALSELGQDLDVILACEGEPGLGN GGLGRLAACYLDSLATLERPSIGYGIRYEFGIFRQEIVDGWQVEKTDNWLVRGNPWEIDKPDASYTVNWG GHTEQYEDVTGRLRVRWVPQRVLQGVSYDTPVQGYGVNTCNTLTLWSARAVESFALEAFNTGDFYKAVDE EVVSETVSKVLYPNDEPEAGKRLRLLQQYFFVTCSLQDILNIHLKRAHLPLHKLPDKWAIQLNDTHPSIA VAELMRLLIDEHHLTWDEAWDLTVRTFGYTNHTLLPEALETWPLRIFGDALPRHLELIYEINDRFLDEVR AKFPDDEERVRRMSLIGEDGGKSVRMAHLATVGSHAVNGVAALHSELLKASVLKDFYEMWPERFGNVTNG VTPRRFLALSNPGLRELLDESIGPGWLTDLERLHGLEAFVDDPAFRARWREVKRANKSRLAEYVHSTTGI ELDPTWMFDVQVKRIHEYKRQHLMVLHIIALYHRLKTNPGLSIPPRVFIFGGKAAPGYFMAKRIIKMITA VGDTVNADPVVNRYLKVVFLPNFNVKNAHLVYPAANLSEQISTAGKEASGTGNMKFMINGALTIGTLDGA NVEIRQEAGAENFFLFGLTESQVEKVKAEGYRPLGHVEKDPELAAVLELLARGEFTHGDTEVLRPIVENL LHHDPFLALADYRSYVDCQDEVSRVWLEDDTWSRMSIRNTARSGKFSSDRAIREYCDEIWGVSPMSVDL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1192 | - | - | 100% (840) | glycogen/starch/alpha-glucan phosphorylases |
| M. vanbaalenii PYR-1 | Mvan_4300 | - | 3e-10 | 24.55% (391) | alpha-glucan phosphorylases |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1363 | glgP | 6e-17 | 23.68% (587) | glycogen phosphorylase GlgP |
| M. gilvum PYR-GCK | Mflv_5144 | - | 0.0 | 93.70% (826) | glycogen/starch/alpha-glucan phosphorylase |
| M. tuberculosis H37Rv | Rv1328 | glgP | 1e-17 | 23.85% (587) | glycogen phosphorylase GlgP |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1854c | - | 0.0 | 74.23% (815) | glycogen phosphorylase |
| M. marinum M | MMAR_2568 | - | 0.0 | 68.85% (838) | carbohydrate phosphorylase |
| M. avium 104 | MAV_1549 | - | 3e-17 | 23.19% (608) | alpha-glucan phosphorylase |
| M. smegmatis MC2 155 | MSMEG_4915 | - | 2e-12 | 26.03% (411) | alpha-glucan phosphorylase family protein |
| M. thermoresistible (build 8) | TH_1052 | glgP | 1e-16 | 22.61% (597) | PROBABLE GLYCOGEN PHOSPHORYLASE GLGP |
| M. ulcerans Agy99 | MUL_3934 | glgP | 2e-20 | 24.54% (603) | glycogen phosphorylase GlgP |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1363|M.bovis_AF2122/97 ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP
Rv1328|M.tuberculosis_H37Rv ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP
MAV_1549|M.avium_104 ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP
MUL_3934|M.ulcerans_Agy99 ----------------MKALRRFTVRTHLSDRLAALYQLSTNLRWSWEKP
MSMEG_4915|M.smegmatis_MC2_155 ----------------MKALRRFTVRTHLPERLAALERLSINLRWSWHKP
TH_1052|M.thermoresistible__bu ----------------VKALRRFTVRAHLPKRLAALERLSVNLRWSWDKP
Mvan_1192|M.vanbaalenii_PYR-1 MTDVINPTSTESVEVNGVKVGPTGQTRSGMTADALRAAVSDHLVYSIARP
Mflv_5144|M.gilvum_PYR-GCK --------------MNGSAVGPTGQTRSGMSADALRAAVRDHLVYSIARP
MAB_1854c|M.abscessus_ATCC_199 -------------MNHSAEPEHDEHSRTGLNADTLRRAIIDHLRYSIGRP
MMAR_2568|M.marinum_M MSDVILP-----AAQAATAATNVGDVRTGMSSDALRQAIEDHLRYSLGRP
: : :* :* :*
Mb1363|M.bovis_AF2122/97 TQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALDAEFLGALDELAA
Rv1328|M.tuberculosis_H37Rv TQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALDAEFLGALDELAA
MAV_1549|M.avium_104 TQDLFASIDPELWQRCGSDPVALLGAVKPARLDELAVDETFLGRLDELTA
MUL_3934|M.ulcerans_Agy99 TQDLFASIDPALWTSCGHDPVAVLGAVKPARLDELALDEEFLGRLDALAA
MSMEG_4915|M.smegmatis_MC2_155 TQDLFATIDPEQWARNDGDPVALLGSVSPKRLDELAADHSFLDRLDELAA
TH_1052|M.thermoresistible__bu TQDLFAAVDEELWRRVGCDPVALLGEISPQRLDELAEDEEFVRRLDEVAA
Mvan_1192|M.vanbaalenii_PYR-1 AAVLTPEHYYRALSLAVRDRMQKRWMATTQDWLDLSAKVTCYLSAEFLMG
Mflv_5144|M.gilvum_PYR-GCK AAVLTPEHYYRALSLAVRDRMQKRWMATTQDWLDLSAKVTCYLSAEFLMG
MAB_1854c|M.abscessus_ATCC_199 ASVLTPAHYYRALALAVRDRMQQRWIASMQTYLDLSRKVAVYLSAEFLMG
MMAR_2568|M.marinum_M AALLEPKHYYRALALAVRDRMQQRWIETTQTYLDLSRKVACYLSAEFLLG
: * . * : . :*: . : : .
Mb1363|M.bovis_AF2122/97 DLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGGLG
Rv1328|M.tuberculosis_H37Rv DLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGGLG
MAV_1549|M.avium_104 DLNDYLSRPLWYQQQQDQ---GAQMPAAIAYFSMEFGVAEVLPNYSGGLG
MUL_3934|M.ulcerans_Agy99 DLNDYLNRPLWYQQQEAD---GVAMPTGIAYFSMEFGVAEVLPNYSGGLG
MSMEG_4915|M.smegmatis_MC2_155 DLDNYLTRPLWYQQQLDT---GVAMPKGIAYFSMEFGVASVLPNYSGGLG
TH_1052|M.thermoresistible__bu DLDDYLSRPLWYQQQLAE---GAELPTGIAYFSMEFGVAEVLPNYSGGLG
Mvan_1192|M.vanbaalenii_PYR-1 PQLGNNLLNLGIEDEARE-----ALSELGQDLDVILACEGEPGLGNGGLG
Mflv_5144|M.gilvum_PYR-GCK PQLGNNLLNLGIEKQARE-----ALSDLGQDLDEVLACEGEPGLGNGGLG
MAB_1854c|M.abscessus_ATCC_199 PQLGNNLLNLQIEQQARD-----ALSALGQDIDEVLACEEEPGLGNGGLG
MMAR_2568|M.marinum_M PHLGNNLLNLQIEEEARA-----ALTALGQDFDEVLACEEEPGLGNGGLG
. * :.: :. :. :. .****
Mb1363|M.bovis_AF2122/97 ILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQG
Rv1328|M.tuberculosis_H37Rv ILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQG
MAV_1549|M.avium_104 ILAGDHLKSASDLGVPLVAVGLYYRSGYFRQSLTADGWQHENYPALDPQG
MUL_3934|M.ulcerans_Agy99 ILAGDHLKAASDLGLPLIAVGLYYRSGYFRQSLTADGWQQETYPSLDPQG
MSMEG_4915|M.smegmatis_MC2_155 ILAGDHLKSASDLGLPLIAVGLYYRSGYFRQSLTADGWQHENYPSLDPQG
TH_1052|M.thermoresistible__bu ILAGDHLKSASDDGLPLIGVGLYYRSGYFRQSLSPDGWQRESYPSIDPQG
Mvan_1192|M.vanbaalenii_PYR-1 RLAACYLDSLATLERPSIGYGIRYEFGIFRQEIV-DGWQVEKTDNWLVRG
Mflv_5144|M.gilvum_PYR-GCK RLAACYLDSLATLERPSIGYGIRYEFGIFRQEIS-DGWQVEKTDNWLVRG
MAB_1854c|M.abscessus_ATCC_199 RLAACYLDSLATLDRPAIGYGIRYEYGIFDQEIR-DGWQVEKTDNWLDNG
MMAR_2568|M.marinum_M RLAACYLDSLATLQRPAVGYGIRYEFGIFDQEIR-DGWQVEKTDNWLADG
**. :*.: : * :. *: *. * * *.: **** *. *
Mb1363|M.bovis_AF2122/97 LPLRLLTDANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPEN
Rv1328|M.tuberculosis_H37Rv LPLRLLTDANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPEN
MAV_1549|M.avium_104 LPLRLLTDATGDPALVELTLPDSAQLHARIWVAQVGRVPLLLLDSDVPEN
MUL_3934|M.ulcerans_Agy99 LPLRLLTNANGDPVLVELTLRDSARLRARIWVAQVGRVPLLLLDSDVPEN
MSMEG_4915|M.smegmatis_MC2_155 LPLRLLTAADGDPVLIELALPEGRDLRARVWIAQVGRIPLLLLDSDIPEN
TH_1052|M.thermoresistible__bu LPLRLLTDKSGAPVLIEVTLP-HAILRARVWVAQVGRVPLLLLDSDIPEN
Mvan_1192|M.vanbaalenii_PYR-1 NPWEIDKPDASYTVNWGGHTEQYEDVTGRLRVRWVPQRVLQGVSYDTPVQ
Mflv_5144|M.gilvum_PYR-GCK NPWEIDKPDASYVVNWGGHTEQYEDVTGRLRVRWVPQRVLQGVSYDTPVQ
MAB_1854c|M.abscessus_ATCC_199 NPWEIGKPDLNFIVGWGGHTEQYLDEHGNFRARWVPQRFLKGIPYDTPIQ
MMAR_2568|M.marinum_M NPWEIVKPELNYRVGWGGRTESYIDERDRYRVRWIPQRAVKGVYYGTPIQ
* .: . . . . : : : : . * :
Mb1363|M.bovis_AF2122/97 EHDLR-------------------------------------NVTDRLYG
Rv1328|M.tuberculosis_H37Rv EHDLR-------------------------------------NVTDRLYG
MAV_1549|M.avium_104 EHDLR-------------------------------------GVTDRLYG
MUL_3934|M.ulcerans_Agy99 EHDLR-------------------------------------SVTDRLYG
MSMEG_4915|M.smegmatis_MC2_155 EHDLR-------------------------------------GTTDRLYG
TH_1052|M.thermoresistible__bu DHDLR-------------------------------------SVTDRLYG
Mvan_1192|M.vanbaalenii_PYR-1 GYGVNTCNTLTLWSARAVESFALEAFNTGDFYKAVDEEVVSETVSKVLYP
Mflv_5144|M.gilvum_PYR-GCK GYGVNTCNTLTLWSARAVESFALEAFNTGDFYKAVDEEVVSETVSKVLYP
MAB_1854c|M.abscessus_ATCC_199 GYGVNTCNTLTLWSARAVQSFELDAFNAGDYYKAVEDEVSSETVTKVLYP
MMAR_2568|M.marinum_M GYGVNTCNTLTLWSARAIQSLALDAFNAGDYYRAVDDQVVSETVTKVLYP
:.:. .:. **
Mb1363|M.bovis_AF2122/97 GD-----------QEHRIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMN
Rv1328|M.tuberculosis_H37Rv GD-----------QEHRIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMN
MAV_1549|M.avium_104 GD-----------QEHRMRQEILAGIGGVRAIRAYTTIHGLPEPEVFHMN
MUL_3934|M.ulcerans_Agy99 GD-----------QEHRIKQEILAGIGGIRAIRAFTAIQGLPAPEVFHMN
MSMEG_4915|M.smegmatis_MC2_155 GD-----------QEHRIKQEILAGIGGVRAIRAFTEIEGLPAPEVFHMN
TH_1052|M.thermoresistible__bu GD-----------QEHRIKQEILAGIGGVRAVRAFTALEGLPQPEVFHMN
Mvan_1192|M.vanbaalenii_PYR-1 NDEPEAGKRLRLLQQYFFVTCSLQDILNIHLKRAHLPLHKLPDKWAIQLN
Mflv_5144|M.gilvum_PYR-GCK NDEPEAGKRLRLLQQYFFVTCSLQDILSIHLKRAHLPLHRLPDKWAIQLN
MAB_1854c|M.abscessus_ATCC_199 NDEPEAGKRLRLLQQHFFVSCSLQRVLHILEDVAERPVNELAEQFALQLN
MMAR_2568|M.marinum_M NDEPEVGKQLRLAQQYFFVSCSLQDILHLLEDFAGLPVQELPNRVAIQLN
.* *:: : * : : * :. *. .:::*
Mb1363|M.bovis_AF2122/97 EGHAGFLGIERIRELVTDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP
Rv1328|M.tuberculosis_H37Rv EGHAGFLGIERIRELVTDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP
MAV_1549|M.avium_104 EGHAGFLGAERIRELMTGSGLDFDTALAVVRSSTVFTTHTPVPAGIDRFP
MUL_3934|M.ulcerans_Agy99 EGHAGFLGAERIRELITDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP
MSMEG_4915|M.smegmatis_MC2_155 EGHAGFLGAERIRELVA-AGLDFDTALAVVRSSTVFTTHTPVPAGIDRFP
TH_1052|M.thermoresistible__bu EGHAGFLGIERIREFMTEAHLDFDTALTMVRASTVFTTHTPVPAGIDRFP
Mvan_1192|M.vanbaalenii_PYR-1 DTHPSIAVAELMRLLIDEHHLTWDEAWDLTVRTFGYTNHTLLPEALETWP
Mflv_5144|M.gilvum_PYR-GCK DTHPSIAVAELMRLLIDEHHLAWDDAWDLTVRTFGYTNHTLLPEALETWP
MAB_1854c|M.abscessus_ATCC_199 DTHPSIGVAELMRLLVDERGLGWDEAWQITVAAFGYTNHTLLPEALETWP
MMAR_2568|M.marinum_M DTHPSIAVADLMRLLVDERDLDWEEAWRITVASLAYTNHTLLPEALETWP
: *..: : :* :: * :: * :. : :*.** :* .:: :*
Mb1363|M.bovis_AF2122/97 LEMVQRYVN---------DQRGD--GRSRLLPGLPADRIVALGAEDDPAK
Rv1328|M.tuberculosis_H37Rv LEMVQRYVN---------DQRGD--GRSRLLPGLPADRIVALGAEDDPAK
MAV_1549|M.avium_104 IDMVRLYFD---------DHADDAAGAPVLLPGVPTARILALGAEDDPTK
MUL_3934|M.ulcerans_Agy99 VEMVQRYFA---------DDE------PTLLPGVPTERILALGAEDDPTK
MSMEG_4915|M.smegmatis_MC2_155 VDMVKRYFG---------SPPGGP-ADSRLLPGVPLDRVIAFGAEDDPSK
TH_1052|M.thermoresistible__bu LEMVRRYFG---------ADGGP-LAESSLLPGVPMERILALGAEADPAT
Mvan_1192|M.vanbaalenii_PYR-1 LRIFGDALPRHLELIYEINDRFLDEVRAKFPDDEERVRRMSLIGEDGGKS
Mflv_5144|M.gilvum_PYR-GCK LRIFGEALPRHLELIYEINDRFLDEVRARFPGDEERVSRMSLIGEDGGKS
MAB_1854c|M.abscessus_ATCC_199 LGLFAESLPRHLEIIYEINRRFLDEVRAHFPGDEARVRRMSLIGEDGGKS
MMAR_2568|M.marinum_M LSMFERFLPRHLEIIYEINRRFLDEVRARFPGDENRVRRMSLIGEDGDRS
: :. . . : . ::: .* . .
Mb1363|M.bovis_AF2122/97 FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWAGFDPDEVPIGSVTNG
Rv1328|M.tuberculosis_H37Rv FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWAGFDPDEVPIGSVTNG
MAV_1549|M.avium_104 FNMAHMGLRLAQRANGVSSLHGRVSR-AMFNELWPGFDSNEVPIGSITNG
MUL_3934|M.ulcerans_Agy99 FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWPGFDHDDVPIGSITNG
MSMEG_4915|M.smegmatis_MC2_155 FNMAHMGLRLAQRANGVSLLHGRVSR-SMFNELWPGFDADEVPIGSITNG
TH_1052|M.thermoresistible__bu FNMAHMGLRLAQRANGVSLLHGQVSR-RMFNDLWPGFDPQEVPIGSITNG
Mvan_1192|M.vanbaalenii_PYR-1 VRMAHLATVGSHAVNGVAALHSELLKASVLKDFYEMWPER---FGNVTNG
Mflv_5144|M.gilvum_PYR-GCK VRMAHLATVGSHAVNGVAALHSELLKQSVLKDFYEMWPER---FGNVTNG
MAB_1854c|M.abscessus_ATCC_199 VRMAHLATVGSHAINGVAALHSELLKESVLKDFYELWPQR---FSNKTNG
MMAR_2568|M.marinum_M IRMAHLAIVGSHAVNGVAALHSELLKTTVLKDFYEMWPQR---FSNKTNG
..***:. :: ***: **..: : :::::: : :.. ***
Mb1363|M.bovis_AF2122/97 VHAPTWAAPQWLQLGRELAG---SDSLREPVVWQRLHQVDPAHLWWIRSQ
Rv1328|M.tuberculosis_H37Rv VHAPTWAAPQWLQLGRELAG---SDSLREPVVWQRLHQVDPAHLWWIRSQ
MAV_1549|M.avium_104 VHARTWAAPQWLQLGYELAG---SDSFSDPGVWLRVQQVDAGHLWGIRCQ
MUL_3934|M.ulcerans_Agy99 VHARTWAAPQWLELGRELAG---SDSFSMPAVWLRLNQVDPGHLWWIRSQ
MSMEG_4915|M.smegmatis_MC2_155 VHAPTWAAPQWLRLGRELIGGELAESALESEVWERLQQVEPGHLWWIRSQ
TH_1052|M.thermoresistible__bu VHAPTWAAPEWIQLGRKLLG---SDPPNEPGVWQRLQHVDPGHIWWIRSE
Mvan_1192|M.vanbaalenii_PYR-1 VTPRRFLALSNPGLRELLDE------SIGPGWLTDLERLHGLEAFVDDPA
Mflv_5144|M.gilvum_PYR-GCK VTPRRFLALSNPGLRALIDD------TIGPGWLTDLERLHGLESFVDDPA
MAB_1854c|M.abscessus_ATCC_199 VTPRRFLALANPGLRELLDD------AIGESWVADLDRLRELEPYAEDSS
MMAR_2568|M.marinum_M VTPRRFVALANPGLRKLLDE------TLGPGWLRNLDRLSELAPLAGDPA
* . : * * : :.::
Mb1363|M.bovis_AF2122/97 LRSMLVEDVRARLRQSWLERGATDAELGWIATAFDPNVLTVGFARRVPTY
Rv1328|M.tuberculosis_H37Rv LRSMLVEDVRARLRQSWLERGATDAELGWIATAFDPNVLTVGFARRVPTY
MAV_1549|M.avium_104 LRSLLVEDVRQRLRRSWLERGATDAELGWLETAFDPDVLTIGFARRVPTY
MUL_3934|M.ulcerans_Agy99 LRSLLVEDVRARLRQSWLERGASEAELGWIPTAFDPDVLTVGFARRVPTY
MSMEG_4915|M.smegmatis_MC2_155 LRETLIADVRARLRRSCLERGAAEAELGWIATAFDPSVLTIGFARRVPTY
TH_1052|M.thermoresistible__bu LRKRLISDVRVRLRRAWLERGATEAELGWIATAFDPEVLTVGFARRVPTY
Mvan_1192|M.vanbaalenii_PYR-1 FRARWREVKRANKSR------LAEYVHSTTGIELDPTWMFDVQVKRIHEY
Mflv_5144|M.gilvum_PYR-GCK FRLRWREVKRANKSR------LAEYVHSITGIELDPTWMFDVQVKRIHEY
MAB_1854c|M.abscessus_ATCC_199 FRTQWREVKRLNKAR------LAEYVLATTGVDLDPSWMFDIQVKRIHEY
MMAR_2568|M.marinum_M FQQRWRAVKRTNKAR------LSDYVRSCTGIELDPDWLFDIQVKRIHEY
:: * . : :: . :** : .:*: *
Mb1363|M.bovis_AF2122/97 KRLTLMLRDPGRLEQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV
Rv1328|M.tuberculosis_H37Rv KRLTLMLRDPDRLEQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV
MAV_1549|M.avium_104 KRLTLMLRDPDRLQQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV
MUL_3934|M.ulcerans_Agy99 KRLTLMLRDSDRLEKLLLDPQ----RPIQLIVAGKSHPADDGGKALIQQV
MSMEG_4915|M.smegmatis_MC2_155 KRLTLMLRDPERLERLLLDPD----RPVQLIVAGKSHPADDGGKALIQQV
TH_1052|M.thermoresistible__bu KRLTLMLRDPDRLEELLLDEE----RPVQLIVAGKSHPADEAGKALIQQI
Mvan_1192|M.vanbaalenii_PYR-1 KRQHLMVLHIIALYHRLKTNPGLSIPPRVFIFGGKAAPGYFMAKRIIKMI
Mflv_5144|M.gilvum_PYR-GCK KRQHLMVLHIIALYQRLKNNPGLTIPPRAFIFGGKAAPGYFMAKRIIKLI
MAB_1854c|M.abscessus_ATCC_199 KRQHLNVLHIVTLYHRLKQNPELRIAPRAFIFGGKAAPGYFMAKRIIKLI
MMAR_2568|M.marinum_M KRQHLNVLHIITAYHRLKLNPNLEIAPRAYIFGGKAAPGYMMAKLIIKLI
** * : . . * * *..**: *. .* :*: :
Mb1363|M.bovis_AF2122/97 VRFADRPQFR------HRIAFLPNYDMSMARLLYWGCDVWLNNPLRPLEA
Rv1328|M.tuberculosis_H37Rv VRFADRPQVR------HRIAFLPNYDMSMARLLYWGCDVWLNNPLRPLEA
MAV_1549|M.avium_104 VRFADRPEVR------HRIAFLPDYDMSMARLLYWGCDVWLNNPLRPLEA
MUL_3934|M.ulcerans_Agy99 VRFADRPEVR------HRIAFLPNYDMSMARFLYWGCDIWLNNPLRPLEA
MSMEG_4915|M.smegmatis_MC2_155 VRFADRPEVR------HRIAFLPDYDMSMARLLYWGCDVWLNNPLRPLEA
TH_1052|M.thermoresistible__bu VRFADRPEVR------HRIAFLPDYDMSMARQLYWGCDVWLNNPLRPLEA
Mvan_1192|M.vanbaalenii_PYR-1 TAVGDTVNADPVVNRYLKVVFLPNFNVKNAHLVYPAANLSEQISTAGKEA
Mflv_5144|M.gilvum_PYR-GCK TAVGDTINADPEVNRCMKLVFLPNFNVKNAHLVYPAANLSEQISTAGKEA
MAB_1854c|M.abscessus_ATCC_199 NAVAEAVNNDPHVSQFIKVAFLPNFNVKSAHLIYPAADLSEQISTAGKEA
MMAR_2568|M.marinum_M NSVAEIVNSDPDVNDRMKVAFIPNFNVQSGQMIYPAADLSEQISTAGKEA
..: : ::.*:*::::. .: :* ..:: : . **
Mb1363|M.bovis_AF2122/97 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDL
Rv1328|M.tuberculosis_H37Rv CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDL
MAV_1549|M.avium_104 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADEQRRDDL
MUL_3934|M.ulcerans_Agy99 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADPERRDDL
MSMEG_4915|M.smegmatis_MC2_155 CGTSGMKSALNGGLNLSIRDGWWDEWFDGENGWEIPTADGLDD-ARRDDL
TH_1052|M.thermoresistible__bu CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPTADGVVDEERRDDL
Mvan_1192|M.vanbaalenii_PYR-1 SGTGNMKFMINGALTIGTLDGANVEIRQEAGAENFFLFG----------L
Mflv_5144|M.gilvum_PYR-GCK SGTGNMKFMINGAVTIGTLDGANVEIRQEAGAENFFLFG----------L
MAB_1854c|M.abscessus_ATCC_199 SGTGNMKFMLNGALTIGTLDGANVEIREEAGPENFFLFG----------L
MMAR_2568|M.marinum_M SGTGNMKFMMNGALTIGTLDGANVEIREQVGAQNFFLFG----------L
.**..** :**.:.:. ** * : . :: . *
Mb1363|M.bovis_AF2122/97 EAGALYDLLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMV
Rv1328|M.tuberculosis_H37Rv EAGALYDLLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMV
MAV_1549|M.avium_104 ESGALYRLLEEAVAPKFYERDERGVPPRWIEMVRHTLQTLGPKVLASRMV
MUL_3934|M.ulcerans_Agy99 EASALYDLLEHSVAPKFYERDERGVPPRWIEMVRHTLQTLGPKVLASRMV
MSMEG_4915|M.smegmatis_MC2_155 EAAALYDLLENAVAPKFYERDEHGVPTRWVEMVRHTLQVLGPKVLASRMV
TH_1052|M.thermoresistible__bu EAAALYDILQNSVVPKFYERDEHGIPTRWVEMVRHTLQVLGPKVLASRMV
Mvan_1192|M.vanbaalenii_PYR-1 TESQVEKVKAEGYRPLGHVEKDPELAAVLELLARGEFTHGDTEVLRPIVE
Mflv_5144|M.gilvum_PYR-GCK TESQVEKVKADGYRPLSHVENDAELAGVLELIARGEFTHGDTEVLRPIVD
MAB_1854c|M.abscessus_ATCC_199 TVEEVQRLVHEGYRPEDFVELNDELRAVLDLIAGGHFSGGDPSVFAPIVE
MMAR_2568|M.marinum_M TVQDVQRVLAAGYRPRDYIRENAELSAALGLIGSGAFSGGDPEVFAPLIA
: : . * . . : : : : ...*: . :
Mb1363|M.bovis_AF2122/97 RDYVEHYYAPAAQSFRRTAG--------AQFDAARELADYRRRAEEAWPK
Rv1328|M.tuberculosis_H37Rv RDYVEHYYAPAAQSFRRTAG--------AQFDAARELADYRRRAEEAWPK
MAV_1549|M.avium_104 RDYVEQYYTPAAQSWRRTIGPAEGATGGAEFGAARELAAYRRRAEEAWPN
MUL_3934|M.ulcerans_Agy99 RDYTERYYAPAAQSRRKTIATAEDGT---EYQAARELAAYRRRVEAAWPS
MSMEG_4915|M.smegmatis_MC2_155 RDYTEKYYLPAAESLRRTVEAASG----EPFGAARELAEFRKRVEEAWPK
TH_1052|M.thermoresistible__bu REYTEKYYAPAARSGRRTAEQVDG----LPFGAARELAAYRQRVQEAWPK
Mvan_1192|M.vanbaalenii_PYR-1 NLLHHDPFLALADYR--------------SYVDCQDEVSRVWLEDDTWSR
Mflv_5144|M.gilvum_PYR-GCK NLVHHDPFLVLADYR--------------SYVDCQDEVSRAWLDRDAWSR
MAB_1854c|M.abscessus_ATCC_199 ALRAHDPFLVLADYS--------------SYIECQQRVSEAWHDVSAWTR
MMAR_2568|M.marinum_M NLSERDPFLVNADYA--------------DYLRAQQEVSNTWQDTESWTR
. : * : .:: . :*.
Mb1363|M.bovis_AF2122/97 IEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPNDVTVQGVLGRVDSGD
Rv1328|M.tuberculosis_H37Rv IEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPNDVTVQGVLGRVDAGD
MAV_1549|M.avium_104 IVITDVDSTGLPDSPVLGSKLTLTATVALGGLAPDEVTVEAVVGRVDGSD
MUL_3934|M.ulcerans_Agy99 IEITDVDSTGLPDTPLLGSKLTLTAIVQLAGLAPDEVTVQAVLGRVDAGD
MSMEG_4915|M.smegmatis_MC2_155 VQITDVDSYGLPDTPLLGCELTLTATVQLAGLRPDEVVVQAVLGRVDDTD
TH_1052|M.thermoresistible__bu VAIVEVDSLGLPDTPLLGSELTLTATVQLAGLRPDEVTVQAALGRVDASD
Mvan_1192|M.vanbaalenii_PYR-1 MSIRNTARSGK----FSSDRAIREYCDEIWGVSPMSVDL-----------
Mflv_5144|M.gilvum_PYR-GCK MSIRNTARSGK----FSSDRAIREYCDEIWGVRPMSVDLE----------
MAB_1854c|M.abscessus_ATCC_199 MSILNTARSGK----FSSDRAIAEYCEEIWGVRPVTVQV-----------
MMAR_2568|M.marinum_M KSILNSAYSGK----FSSDRAIAEYCDDIWNIAAVTIGSRPD--------
* : * . . . : .: . :
Mb1363|M.bovis_AF2122/97 VLMDPVTVEMAHTGTGDGGYEIFSTTTPLPLAGPVGYTVRVLPRHPMLAA
Rv1328|M.tuberculosis_H37Rv VLMDPVTVEMAHTGTGDGGYEIFSTTTPLPLAGPVGYTVRVLPRHPMLAA
MAV_1549|M.avium_104 ALLEPVTVEMSYAGTAEGGNQVFSTTTPLPLAGSVGYTVRVLPRHPMLAA
MUL_3934|M.ulcerans_Agy99 VLVDPVTVEMSYAGHADAGNQVFSTTTPLPMAGALGYTVRVLPRHPMLAA
MSMEG_4915|M.smegmatis_MC2_155 AIVDPVKVPMAHKGPDGNGTDVFSACTPLPVAGPVGYTVRVLPHHRLLAG
TH_1052|M.thermoresistible__bu QLIDPVIVSMTHTGTNHDGTQIFSTTAPLPVAGAVGYTVRVLPHHPLLAG
Mvan_1192|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5144|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1854c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2568|M.marinum_M --------------------------------------------------
Mb1363|M.bovis_AF2122/97 SNELGLVTLA--
Rv1328|M.tuberculosis_H37Rv SNELGLVTLA--
MAV_1549|M.avium_104 GNELGLVTLAR-
MUL_3934|M.ulcerans_Agy99 SNELGLVTLATR
MSMEG_4915|M.smegmatis_MC2_155 DNELGLVTLA--
TH_1052|M.thermoresistible__bu PNELGLIAWA--
Mvan_1192|M.vanbaalenii_PYR-1 ------------
Mflv_5144|M.gilvum_PYR-GCK ------------
MAB_1854c|M.abscessus_ATCC_199 ------------
MMAR_2568|M.marinum_M ------------