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SDVILPAAQAATAATNVGDVRTGMSSDALRQAIEDHLRYSLGRPAALLEPKHYYRALALAVRDRMQQRWI ETTQTYLDLSRKVACYLSAEFLLGPHLGNNLLNLQIEEEARAALTALGQDFDEVLACEEEPGLGNGGLGR LAACYLDSLATLQRPAVGYGIRYEFGIFDQEIRDGWQVEKTDNWLADGNPWEIVKPELNYRVGWGGRTES YIDERDRYRVRWIPQRAVKGVYYGTPIQGYGVNTCNTLTLWSARAIQSLALDAFNAGDYYRAVDDQVVSE TVTKVLYPNDEPEVGKQLRLAQQYFFVSCSLQDILHLLEDFAGLPVQELPNRVAIQLNDTHPSIAVADLM RLLVDERDLDWEEAWRITVASLAYTNHTLLPEALETWPLSMFERFLPRHLEIIYEINRRFLDEVRARFPG DENRVRRMSLIGEDGDRSIRMAHLAIVGSHAVNGVAALHSELLKTTVLKDFYEMWPQRFSNKTNGVTPRR FVALANPGLRKLLDETLGPGWLRNLDRLSELAPLAGDPAFQQRWRAVKRTNKARLSDYVRSCTGIELDPD WLFDIQVKRIHEYKRQHLNVLHIITAYHRLKLNPNLEIAPRAYIFGGKAAPGYMMAKLIIKLINSVAEIV NSDPDVNDRMKVAFIPNFNVQSGQMIYPAADLSEQISTAGKEASGTGNMKFMMNGALTIGTLDGANVEIR EQVGAQNFFLFGLTVQDVQRVLAAGYRPRDYIRENAELSAALGLIGSGAFSGGDPEVFAPLIANLSERDP FLVNADYADYLRAQQEVSNTWQDTESWTRKSILNSAYSGKFSSDRAIAEYCDDIWNIAAVTIGSRPD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2568 | - | - | 100% (838) | carbohydrate phosphorylase |
M. marinum M | MMAR_4070 | glgP | 1e-22 | 24.72% (631) | glycogen phosphorylase GlgP |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1363 | glgP | 5e-17 | 24.45% (589) | glycogen phosphorylase GlgP |
M. gilvum PYR-GCK | Mflv_5144 | - | 0.0 | 70.16% (821) | glycogen/starch/alpha-glucan phosphorylase |
M. tuberculosis H37Rv | Rv1328 | glgP | 2e-17 | 24.79% (589) | glycogen phosphorylase GlgP |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1854c | - | 0.0 | 75.74% (812) | glycogen phosphorylase |
M. avium 104 | MAV_1549 | - | 5e-18 | 26.34% (391) | alpha-glucan phosphorylase |
M. smegmatis MC2 155 | MSMEG_4915 | - | 2e-14 | 25.13% (394) | alpha-glucan phosphorylase family protein |
M. thermoresistible (build 8) | TH_1052 | glgP | 3e-15 | 25.32% (395) | PROBABLE GLYCOGEN PHOSPHORYLASE GLGP |
M. ulcerans Agy99 | MUL_3934 | glgP | 1e-22 | 24.72% (631) | glycogen phosphorylase GlgP |
M. vanbaalenii PYR-1 | Mvan_1192 | - | 0.0 | 68.85% (838) | glycogen/starch/alpha-glucan phosphorylases |
CLUSTAL 2.0.9 multiple sequence alignment Mb1363|M.bovis_AF2122/97 ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP Rv1328|M.tuberculosis_H37Rv ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP MAV_1549|M.avium_104 ----------------MKALRRFTVRAHLPERLAALDQLSTNLRWSWDKP MUL_3934|M.ulcerans_Agy99 ----------------MKALRRFTVRTHLSDRLAALYQLSTNLRWSWEKP MSMEG_4915|M.smegmatis_MC2_155 ----------------MKALRRFTVRTHLPERLAALERLSINLRWSWHKP TH_1052|M.thermoresistible__bu ----------------VKALRRFTVRAHLPKRLAALERLSVNLRWSWDKP MMAR_2568|M.marinum_M MSDVILP-----AAQAATAATNVGDVRTGMSSDALRQAIEDHLRYSLGRP MAB_1854c|M.abscessus_ATCC_199 -------------MNHSAEPEHDEHSRTGLNADTLRRAIIDHLRYSIGRP Mflv_5144|M.gilvum_PYR-GCK --------------MNGSAVGPTGQTRSGMSADALRAAVRDHLVYSIARP Mvan_1192|M.vanbaalenii_PYR-1 MTDVINPTSTESVEVNGVKVGPTGQTRSGMTADALRAAVSDHLVYSIARP : : :* :* :* Mb1363|M.bovis_AF2122/97 TQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALDAEFLGALDELAA Rv1328|M.tuberculosis_H37Rv TQDLFAAIDPALWEQCGHDPVALLGAVNPARLDELALDAEFLGALDELAA MAV_1549|M.avium_104 TQDLFASIDPELWQRCGSDPVALLGAVKPARLDELAVDETFLGRLDELTA MUL_3934|M.ulcerans_Agy99 TQDLFASIDPALWTSCGHDPVAVLGAVKPARLDELALDEEFLGRLDALAA MSMEG_4915|M.smegmatis_MC2_155 TQDLFATIDPEQWARNDGDPVALLGSVSPKRLDELAADHSFLDRLDELAA TH_1052|M.thermoresistible__bu TQDLFAAVDEELWRRVGCDPVALLGEISPQRLDELAEDEEFVRRLDEVAA MMAR_2568|M.marinum_M AALLEPKHYYRALALAVRDRMQQRWIETTQTYLDLSRKVACYLSAEFLLG MAB_1854c|M.abscessus_ATCC_199 ASVLTPAHYYRALALAVRDRMQQRWIASMQTYLDLSRKVAVYLSAEFLMG Mflv_5144|M.gilvum_PYR-GCK AAVLTPEHYYRALSLAVRDRMQKRWMATTQDWLDLSAKVTCYLSAEFLMG Mvan_1192|M.vanbaalenii_PYR-1 AAVLTPEHYYRALSLAVRDRMQKRWMATTQDWLDLSAKVTCYLSAEFLMG : * . * : . :*: . : : . Mb1363|M.bovis_AF2122/97 DLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGGLG Rv1328|M.tuberculosis_H37Rv DLNDYLSRPLWYQEQQDAGVAAQALPTGIAYFSLEFGVAEVLPNYSGGLG MAV_1549|M.avium_104 DLNDYLSRPLWYQQQQDQ---GAQMPAAIAYFSMEFGVAEVLPNYSGGLG MUL_3934|M.ulcerans_Agy99 DLNDYLNRPLWYQQQEAD---GVAMPTGIAYFSMEFGVAEVLPNYSGGLG MSMEG_4915|M.smegmatis_MC2_155 DLDNYLTRPLWYQQQLDT---GVAMPKGIAYFSMEFGVASVLPNYSGGLG TH_1052|M.thermoresistible__bu DLDDYLSRPLWYQQQLAE---GAELPTGIAYFSMEFGVAEVLPNYSGGLG MMAR_2568|M.marinum_M PHLGNNLLNLQIEEEARA-----ALTALGQDFDEVLACEEEPGLGNGGLG MAB_1854c|M.abscessus_ATCC_199 PQLGNNLLNLQIEQQARD-----ALSALGQDIDEVLACEEEPGLGNGGLG Mflv_5144|M.gilvum_PYR-GCK PQLGNNLLNLGIEKQARE-----ALSDLGQDLDEVLACEGEPGLGNGGLG Mvan_1192|M.vanbaalenii_PYR-1 PQLGNNLLNLGIEDEARE-----ALSELGQDLDVILACEGEPGLGNGGLG . * :.: :. :. :. .**** Mb1363|M.bovis_AF2122/97 ILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQG Rv1328|M.tuberculosis_H37Rv ILAGDHLKSASDLGVPLIAVGLYYRSGYFRQSLTADGWQHETYPSLDPQG MAV_1549|M.avium_104 ILAGDHLKSASDLGVPLVAVGLYYRSGYFRQSLTADGWQHENYPALDPQG MUL_3934|M.ulcerans_Agy99 ILAGDHLKAASDLGLPLIAVGLYYRSGYFRQSLTADGWQQETYPSLDPQG MSMEG_4915|M.smegmatis_MC2_155 ILAGDHLKSASDLGLPLIAVGLYYRSGYFRQSLTADGWQHENYPSLDPQG TH_1052|M.thermoresistible__bu ILAGDHLKSASDDGLPLIGVGLYYRSGYFRQSLSPDGWQRESYPSIDPQG MMAR_2568|M.marinum_M RLAACYLDSLATLQRPAVGYGIRYEFGIFDQEIR-DGWQVEKTDNWLADG MAB_1854c|M.abscessus_ATCC_199 RLAACYLDSLATLDRPAIGYGIRYEYGIFDQEIR-DGWQVEKTDNWLDNG Mflv_5144|M.gilvum_PYR-GCK RLAACYLDSLATLERPSIGYGIRYEFGIFRQEIS-DGWQVEKTDNWLVRG Mvan_1192|M.vanbaalenii_PYR-1 RLAACYLDSLATLERPSIGYGIRYEFGIFRQEIV-DGWQVEKTDNWLVRG **. :*.: : * :. *: *. * * *.: **** *. * Mb1363|M.bovis_AF2122/97 LPLRLLTDANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPEN Rv1328|M.tuberculosis_H37Rv LPLRLLTDANGDPVLVEVALGDNAVLRARIWVAQVGRVPLLLLDSDIPEN MAV_1549|M.avium_104 LPLRLLTDATGDPALVELTLPDSAQLHARIWVAQVGRVPLLLLDSDVPEN MUL_3934|M.ulcerans_Agy99 LPLRLLTNANGDPVLVELTLRDSARLRARIWVAQVGRVPLLLLDSDVPEN MSMEG_4915|M.smegmatis_MC2_155 LPLRLLTAADGDPVLIELALPEGRDLRARVWIAQVGRIPLLLLDSDIPEN TH_1052|M.thermoresistible__bu LPLRLLTDKSGAPVLIEVTLP-HAILRARVWVAQVGRVPLLLLDSDIPEN MMAR_2568|M.marinum_M NPWEIVKPELNYRVGWGGRTESYIDERDRYRVRWIPQRAVKGVYYGTPIQ MAB_1854c|M.abscessus_ATCC_199 NPWEIGKPDLNFIVGWGGHTEQYLDEHGNFRARWVPQRFLKGIPYDTPIQ Mflv_5144|M.gilvum_PYR-GCK NPWEIDKPDASYVVNWGGHTEQYEDVTGRLRVRWVPQRVLQGVSYDTPVQ Mvan_1192|M.vanbaalenii_PYR-1 NPWEIDKPDASYTVNWGGHTEQYEDVTGRLRVRWVPQRVLQGVSYDTPVQ * .: . . . . : : : : . * : Mb1363|M.bovis_AF2122/97 EHDLR-------------------------------------NVTDRLYG Rv1328|M.tuberculosis_H37Rv EHDLR-------------------------------------NVTDRLYG MAV_1549|M.avium_104 EHDLR-------------------------------------GVTDRLYG MUL_3934|M.ulcerans_Agy99 EHDLR-------------------------------------SVTDRLYG MSMEG_4915|M.smegmatis_MC2_155 EHDLR-------------------------------------GTTDRLYG TH_1052|M.thermoresistible__bu DHDLR-------------------------------------SVTDRLYG MMAR_2568|M.marinum_M GYGVNTCNTLTLWSARAIQSLALDAFNAGDYYRAVDDQVVSETVTKVLYP MAB_1854c|M.abscessus_ATCC_199 GYGVNTCNTLTLWSARAVQSFELDAFNAGDYYKAVEDEVSSETVTKVLYP Mflv_5144|M.gilvum_PYR-GCK GYGVNTCNTLTLWSARAVESFALEAFNTGDFYKAVDEEVVSETVSKVLYP Mvan_1192|M.vanbaalenii_PYR-1 GYGVNTCNTLTLWSARAVESFALEAFNTGDFYKAVDEEVVSETVSKVLYP :.:. .:. ** Mb1363|M.bovis_AF2122/97 GD-----------QEHRIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMN Rv1328|M.tuberculosis_H37Rv GD-----------QEHRIKQEILAGIGGVRAIRAYTAVEKLTPPEVFHMN MAV_1549|M.avium_104 GD-----------QEHRMRQEILAGIGGVRAIRAYTTIHGLPEPEVFHMN MUL_3934|M.ulcerans_Agy99 GD-----------QEHRIKQEILAGIGGIRAIRAFTAIQGLPAPEVFHMN MSMEG_4915|M.smegmatis_MC2_155 GD-----------QEHRIKQEILAGIGGVRAIRAFTEIEGLPAPEVFHMN TH_1052|M.thermoresistible__bu GD-----------QEHRIKQEILAGIGGVRAVRAFTALEGLPQPEVFHMN MMAR_2568|M.marinum_M NDEPEVGKQLRLAQQYFFVSCSLQDILHLLEDFAGLPVQELPNRVAIQLN MAB_1854c|M.abscessus_ATCC_199 NDEPEAGKRLRLLQQHFFVSCSLQRVLHILEDVAERPVNELAEQFALQLN Mflv_5144|M.gilvum_PYR-GCK NDEPEAGKRLRLLQQYFFVTCSLQDILSIHLKRAHLPLHRLPDKWAIQLN Mvan_1192|M.vanbaalenii_PYR-1 NDEPEAGKRLRLLQQYFFVTCSLQDILNIHLKRAHLPLHKLPDKWAIQLN .* *:: : * : : * :. *. .:::* Mb1363|M.bovis_AF2122/97 EGHAGFLGIERIRELVTDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP Rv1328|M.tuberculosis_H37Rv EGHAGFLGIERIRELVTDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP MAV_1549|M.avium_104 EGHAGFLGAERIRELMTGSGLDFDTALAVVRSSTVFTTHTPVPAGIDRFP MUL_3934|M.ulcerans_Agy99 EGHAGFLGAERIRELITDAGLDFDTALTVVRSSTVFTTHTPVPAGIDRFP MSMEG_4915|M.smegmatis_MC2_155 EGHAGFLGAERIRELVA-AGLDFDTALAVVRSSTVFTTHTPVPAGIDRFP TH_1052|M.thermoresistible__bu EGHAGFLGIERIREFMTEAHLDFDTALTMVRASTVFTTHTPVPAGIDRFP MMAR_2568|M.marinum_M DTHPSIAVADLMRLLVDERDLDWEEAWRITVASLAYTNHTLLPEALETWP MAB_1854c|M.abscessus_ATCC_199 DTHPSIGVAELMRLLVDERGLGWDEAWQITVAAFGYTNHTLLPEALETWP Mflv_5144|M.gilvum_PYR-GCK DTHPSIAVAELMRLLIDEHHLAWDDAWDLTVRTFGYTNHTLLPEALETWP Mvan_1192|M.vanbaalenii_PYR-1 DTHPSIAVAELMRLLIDEHHLTWDEAWDLTVRTFGYTNHTLLPEALETWP : *..: : :* :: * :: * :. : :*.** :* .:: :* Mb1363|M.bovis_AF2122/97 LEMVQRYVN---------DQRGD--GRSRLLPGLPADRIVALGAEDDPAK Rv1328|M.tuberculosis_H37Rv LEMVQRYVN---------DQRGD--GRSRLLPGLPADRIVALGAEDDPAK MAV_1549|M.avium_104 IDMVRLYFD---------DHADDAAGAPVLLPGVPTARILALGAEDDPTK MUL_3934|M.ulcerans_Agy99 VEMVQRYFA---------DDE------PTLLPGVPTERILALGAEDDPTK MSMEG_4915|M.smegmatis_MC2_155 VDMVKRYFG---------SPPGGP-ADSRLLPGVPLDRVIAFGAEDDPSK TH_1052|M.thermoresistible__bu LEMVRRYFG---------ADGGP-LAESSLLPGVPMERILALGAEADPAT MMAR_2568|M.marinum_M LSMFERFLPRHLEIIYEINRRFLDEVRARFPGDENRVRRMSLIGEDGDRS MAB_1854c|M.abscessus_ATCC_199 LGLFAESLPRHLEIIYEINRRFLDEVRAHFPGDEARVRRMSLIGEDGGKS Mflv_5144|M.gilvum_PYR-GCK LRIFGEALPRHLELIYEINDRFLDEVRARFPGDEERVSRMSLIGEDGGKS Mvan_1192|M.vanbaalenii_PYR-1 LRIFGDALPRHLELIYEINDRFLDEVRAKFPDDEERVRRMSLIGEDGGKS : :. . . : . ::: .* . . Mb1363|M.bovis_AF2122/97 FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWAGFDPDEVPIGSVTNG Rv1328|M.tuberculosis_H37Rv FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWAGFDPDEVPIGSVTNG MAV_1549|M.avium_104 FNMAHMGLRLAQRANGVSSLHGRVSR-AMFNELWPGFDSNEVPIGSITNG MUL_3934|M.ulcerans_Agy99 FNMAHMGLRLAQRANGVSLLHGRVSR-AMFNELWPGFDHDDVPIGSITNG MSMEG_4915|M.smegmatis_MC2_155 FNMAHMGLRLAQRANGVSLLHGRVSR-SMFNELWPGFDADEVPIGSITNG TH_1052|M.thermoresistible__bu FNMAHMGLRLAQRANGVSLLHGQVSR-RMFNDLWPGFDPQEVPIGSITNG MMAR_2568|M.marinum_M IRMAHLAIVGSHAVNGVAALHSELLKTTVLKDFYEMWPQR---FSNKTNG MAB_1854c|M.abscessus_ATCC_199 VRMAHLATVGSHAINGVAALHSELLKESVLKDFYELWPQR---FSNKTNG Mflv_5144|M.gilvum_PYR-GCK VRMAHLATVGSHAVNGVAALHSELLKQSVLKDFYEMWPER---FGNVTNG Mvan_1192|M.vanbaalenii_PYR-1 VRMAHLATVGSHAVNGVAALHSELLKASVLKDFYEMWPER---FGNVTNG ..***:. :: ***: **..: : :::::: : :.. *** Mb1363|M.bovis_AF2122/97 VHAPTWAAPQWLQLGRELAG---SDSLREPVVWQRLHQVDPAHLWWIRSQ Rv1328|M.tuberculosis_H37Rv VHAPTWAAPQWLQLGRELAG---SDSLREPVVWQRLHQVDPAHLWWIRSQ MAV_1549|M.avium_104 VHARTWAAPQWLQLGYELAG---SDSFSDPGVWLRVQQVDAGHLWGIRCQ MUL_3934|M.ulcerans_Agy99 VHARTWAAPQWLELGRELAG---SDSFSMPAVWLRLNQVDPGHLWWIRSQ MSMEG_4915|M.smegmatis_MC2_155 VHAPTWAAPQWLRLGRELIGGELAESALESEVWERLQQVEPGHLWWIRSQ TH_1052|M.thermoresistible__bu VHAPTWAAPEWIQLGRKLLG---SDPPNEPGVWQRLQHVDPGHIWWIRSE MMAR_2568|M.marinum_M VTPRRFVALANPGLRKLLDE------TLGPGWLRNLDRLSELAPLAGDPA MAB_1854c|M.abscessus_ATCC_199 VTPRRFLALANPGLRELLDD------AIGESWVADLDRLRELEPYAEDSS Mflv_5144|M.gilvum_PYR-GCK VTPRRFLALSNPGLRALIDD------TIGPGWLTDLERLHGLESFVDDPA Mvan_1192|M.vanbaalenii_PYR-1 VTPRRFLALSNPGLRELLDE------SIGPGWLTDLERLHGLEAFVDDPA * . : * * : :.:: Mb1363|M.bovis_AF2122/97 LRSMLVEDVRARLRQSWLERGATDAELGWIATAFDPNVLTVGFARRVPTY Rv1328|M.tuberculosis_H37Rv LRSMLVEDVRARLRQSWLERGATDAELGWIATAFDPNVLTVGFARRVPTY MAV_1549|M.avium_104 LRSLLVEDVRQRLRRSWLERGATDAELGWLETAFDPDVLTIGFARRVPTY MUL_3934|M.ulcerans_Agy99 LRSLLVEDVRARLRQSWLERGASEAELGWIPTAFDPDVLTVGFARRVPTY MSMEG_4915|M.smegmatis_MC2_155 LRETLIADVRARLRRSCLERGAAEAELGWIATAFDPSVLTIGFARRVPTY TH_1052|M.thermoresistible__bu LRKRLISDVRVRLRRAWLERGATEAELGWIATAFDPEVLTVGFARRVPTY MMAR_2568|M.marinum_M FQQRWRAVKRTNKAR------LSDYVRSCTGIELDPDWLFDIQVKRIHEY MAB_1854c|M.abscessus_ATCC_199 FRTQWREVKRLNKAR------LAEYVLATTGVDLDPSWMFDIQVKRIHEY Mflv_5144|M.gilvum_PYR-GCK FRLRWREVKRANKSR------LAEYVHSITGIELDPTWMFDVQVKRIHEY Mvan_1192|M.vanbaalenii_PYR-1 FRARWREVKRANKSR------LAEYVHSTTGIELDPTWMFDVQVKRIHEY :: * . : :: . :** : .:*: * Mb1363|M.bovis_AF2122/97 KRLTLMLRDPGRLEQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV Rv1328|M.tuberculosis_H37Rv KRLTLMLRDPDRLEQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV MAV_1549|M.avium_104 KRLTLMLRDPDRLQQLLLDEQ----RPIQLIVAGKSHPADDGGKALIQQV MUL_3934|M.ulcerans_Agy99 KRLTLMLRDSDRLEKLLLDPQ----RPIQLIVAGKSHPADDGGKALIQQV MSMEG_4915|M.smegmatis_MC2_155 KRLTLMLRDPERLERLLLDPD----RPVQLIVAGKSHPADDGGKALIQQV TH_1052|M.thermoresistible__bu KRLTLMLRDPDRLEELLLDEE----RPVQLIVAGKSHPADEAGKALIQQI MMAR_2568|M.marinum_M KRQHLNVLHIITAYHRLKLNPNLEIAPRAYIFGGKAAPGYMMAKLIIKLI MAB_1854c|M.abscessus_ATCC_199 KRQHLNVLHIVTLYHRLKQNPELRIAPRAFIFGGKAAPGYFMAKRIIKLI Mflv_5144|M.gilvum_PYR-GCK KRQHLMVLHIIALYQRLKNNPGLTIPPRAFIFGGKAAPGYFMAKRIIKLI Mvan_1192|M.vanbaalenii_PYR-1 KRQHLMVLHIIALYHRLKTNPGLSIPPRVFIFGGKAAPGYFMAKRIIKMI ** * : . . * * *..**: *. .* :*: : Mb1363|M.bovis_AF2122/97 VRFADRPQFR------HRIAFLPNYDMSMARLLYWGCDVWLNNPLRPLEA Rv1328|M.tuberculosis_H37Rv VRFADRPQVR------HRIAFLPNYDMSMARLLYWGCDVWLNNPLRPLEA MAV_1549|M.avium_104 VRFADRPEVR------HRIAFLPDYDMSMARLLYWGCDVWLNNPLRPLEA MUL_3934|M.ulcerans_Agy99 VRFADRPEVR------HRIAFLPNYDMSMARFLYWGCDIWLNNPLRPLEA MSMEG_4915|M.smegmatis_MC2_155 VRFADRPEVR------HRIAFLPDYDMSMARLLYWGCDVWLNNPLRPLEA TH_1052|M.thermoresistible__bu VRFADRPEVR------HRIAFLPDYDMSMARQLYWGCDVWLNNPLRPLEA MMAR_2568|M.marinum_M NSVAEIVNSDPDVNDRMKVAFIPNFNVQSGQMIYPAADLSEQISTAGKEA MAB_1854c|M.abscessus_ATCC_199 NAVAEAVNNDPHVSQFIKVAFLPNFNVKSAHLIYPAADLSEQISTAGKEA Mflv_5144|M.gilvum_PYR-GCK TAVGDTINADPEVNRCMKLVFLPNFNVKNAHLVYPAANLSEQISTAGKEA Mvan_1192|M.vanbaalenii_PYR-1 TAVGDTVNADPVVNRYLKVVFLPNFNVKNAHLVYPAANLSEQISTAGKEA ..: : ::.*:*::::. .: :* ..:: : . ** Mb1363|M.bovis_AF2122/97 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDL Rv1328|M.tuberculosis_H37Rv CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADENRRDDL MAV_1549|M.avium_104 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADEQRRDDL MUL_3934|M.ulcerans_Agy99 CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPSADGVADPERRDDL MSMEG_4915|M.smegmatis_MC2_155 CGTSGMKSALNGGLNLSIRDGWWDEWFDGENGWEIPTADGLDD-ARRDDL TH_1052|M.thermoresistible__bu CGTSGMKSALNGGLNLSIRDGWWDEWYDGENGWEIPTADGVVDEERRDDL MMAR_2568|M.marinum_M SGTGNMKFMMNGALTIGTLDGANVEIREQVGAQNFFLFG----------L MAB_1854c|M.abscessus_ATCC_199 SGTGNMKFMLNGALTIGTLDGANVEIREEAGPENFFLFG----------L Mflv_5144|M.gilvum_PYR-GCK SGTGNMKFMINGAVTIGTLDGANVEIRQEAGAENFFLFG----------L Mvan_1192|M.vanbaalenii_PYR-1 SGTGNMKFMINGALTIGTLDGANVEIRQEAGAENFFLFG----------L .**..** :**.:.:. ** * : . :: . * Mb1363|M.bovis_AF2122/97 EAGALYDLLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMV Rv1328|M.tuberculosis_H37Rv EAGALYDLLAQAVAPKFYERDERGVPQRWVEMVRHTLQTLGPKVLASRMV MAV_1549|M.avium_104 ESGALYRLLEEAVAPKFYERDERGVPPRWIEMVRHTLQTLGPKVLASRMV MUL_3934|M.ulcerans_Agy99 EASALYDLLEHSVAPKFYERDERGVPPRWIEMVRHTLQTLGPKVLASRMV MSMEG_4915|M.smegmatis_MC2_155 EAAALYDLLENAVAPKFYERDEHGVPTRWVEMVRHTLQVLGPKVLASRMV TH_1052|M.thermoresistible__bu EAAALYDILQNSVVPKFYERDEHGIPTRWVEMVRHTLQVLGPKVLASRMV MMAR_2568|M.marinum_M TVQDVQRVLAAGYRPRDYIRENAELSAALGLIGSGAFSGGDPEVFAPLIA MAB_1854c|M.abscessus_ATCC_199 TVEEVQRLVHEGYRPEDFVELNDELRAVLDLIAGGHFSGGDPSVFAPIVE Mflv_5144|M.gilvum_PYR-GCK TESQVEKVKADGYRPLSHVENDAELAGVLELIARGEFTHGDTEVLRPIVD Mvan_1192|M.vanbaalenii_PYR-1 TESQVEKVKAEGYRPLGHVEKDPELAAVLELLARGEFTHGDTEVLRPIVE : : . * . . : : : : ...*: . : Mb1363|M.bovis_AF2122/97 RDYVEHYYAPAAQSFRRTAG--------AQFDAARELADYRRRAEEAWPK Rv1328|M.tuberculosis_H37Rv RDYVEHYYAPAAQSFRRTAG--------AQFDAARELADYRRRAEEAWPK MAV_1549|M.avium_104 RDYVEQYYTPAAQSWRRTIGPAEGATGGAEFGAARELAAYRRRAEEAWPN MUL_3934|M.ulcerans_Agy99 RDYTERYYAPAAQSRRKTIATAEDGT---EYQAARELAAYRRRVEAAWPS MSMEG_4915|M.smegmatis_MC2_155 RDYTEKYYLPAAESLRRTVEAASG----EPFGAARELAEFRKRVEEAWPK TH_1052|M.thermoresistible__bu REYTEKYYAPAARSGRRTAEQVDG----LPFGAARELAAYRQRVQEAWPK MMAR_2568|M.marinum_M NLSERDPFLVNADYA--------------DYLRAQQEVSNTWQDTESWTR MAB_1854c|M.abscessus_ATCC_199 ALRAHDPFLVLADYS--------------SYIECQQRVSEAWHDVSAWTR Mflv_5144|M.gilvum_PYR-GCK NLVHHDPFLVLADYR--------------SYVDCQDEVSRAWLDRDAWSR Mvan_1192|M.vanbaalenii_PYR-1 NLLHHDPFLALADYR--------------SYVDCQDEVSRVWLEDDTWSR . : * : .:: . :*. Mb1363|M.bovis_AF2122/97 IEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPNDVTVQGVLGRVDSGD Rv1328|M.tuberculosis_H37Rv IEIADVDSTGLPDTPLLGSQLTLTATVRLAGLRPNDVTVQGVLGRVDAGD MAV_1549|M.avium_104 IVITDVDSTGLPDSPVLGSKLTLTATVALGGLAPDEVTVEAVVGRVDGSD MUL_3934|M.ulcerans_Agy99 IEITDVDSTGLPDTPLLGSKLTLTAIVQLAGLAPDEVTVQAVLGRVDAGD MSMEG_4915|M.smegmatis_MC2_155 VQITDVDSYGLPDTPLLGCELTLTATVQLAGLRPDEVVVQAVLGRVDDTD TH_1052|M.thermoresistible__bu VAIVEVDSLGLPDTPLLGSELTLTATVQLAGLRPDEVTVQAALGRVDASD MMAR_2568|M.marinum_M KSILNSAYSGK----FSSDRAIAEYCDDIWNIAAVTIGSRPD-------- MAB_1854c|M.abscessus_ATCC_199 MSILNTARSGK----FSSDRAIAEYCEEIWGVRPVTVQV----------- Mflv_5144|M.gilvum_PYR-GCK MSIRNTARSGK----FSSDRAIREYCDEIWGVRPMSVDLE---------- Mvan_1192|M.vanbaalenii_PYR-1 MSIRNTARSGK----FSSDRAIREYCDEIWGVSPMSVDL----------- * : * . . . : .: . : Mb1363|M.bovis_AF2122/97 VLMDPVTVEMAHTGTGDGGYEIFSTTTPLPLAGPVGYTVRVLPRHPMLAA Rv1328|M.tuberculosis_H37Rv VLMDPVTVEMAHTGTGDGGYEIFSTTTPLPLAGPVGYTVRVLPRHPMLAA MAV_1549|M.avium_104 ALLEPVTVEMSYAGTAEGGNQVFSTTTPLPLAGSVGYTVRVLPRHPMLAA MUL_3934|M.ulcerans_Agy99 VLVDPVTVEMSYAGHADAGNQVFSTTTPLPMAGALGYTVRVLPRHPMLAA MSMEG_4915|M.smegmatis_MC2_155 AIVDPVKVPMAHKGPDGNGTDVFSACTPLPVAGPVGYTVRVLPHHRLLAG TH_1052|M.thermoresistible__bu QLIDPVIVSMTHTGTNHDGTQIFSTTAPLPVAGAVGYTVRVLPHHPLLAG MMAR_2568|M.marinum_M -------------------------------------------------- MAB_1854c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_5144|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1192|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb1363|M.bovis_AF2122/97 SNELGLVTLA-- Rv1328|M.tuberculosis_H37Rv SNELGLVTLA-- MAV_1549|M.avium_104 GNELGLVTLAR- MUL_3934|M.ulcerans_Agy99 SNELGLVTLATR MSMEG_4915|M.smegmatis_MC2_155 DNELGLVTLA-- TH_1052|M.thermoresistible__bu PNELGLIAWA-- MMAR_2568|M.marinum_M ------------ MAB_1854c|M.abscessus_ATCC_199 ------------ Mflv_5144|M.gilvum_PYR-GCK ------------ Mvan_1192|M.vanbaalenii_PYR-1 ------------