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DHVTFVPSPDQFSFTFGGAEPVMRIRPGTVLTLWTEDAYGGRITSTDSVATTALDTEDLNPQTGPFWIEG AEPGDTLAVHLVDLTPARSWGASTLIPFFGGLTSVPVSPTLQDALPERTWIYEYDSAAKTLAFDARGSDF SVALPANPMLGTVGVAPARREVRTSLVPDVFGGNMDTPEMAAGATCYLRVNVPGALFSLGDGHYRQGEGE SCGTAVEGAMHVTAIVDLIKSGGPAWPRLETDTHLMCVGSGRPLEEAWRAGQVEMITWLGELYGLDRLDA YQLLTQISLAPIANVVDTNYSSVTKIDKRLLPAAPAYQGIHAELRSAAAALGTVNY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1186 | - | - | 100% (337) | acetamidase/formamidase |
| M. vanbaalenii PYR-1 | Mvan_0644 | - | e-123 | 63.86% (332) | acetamidase/formamidase |
| M. vanbaalenii PYR-1 | Mvan_0290 | - | 1e-24 | 29.02% (286) | acetamidase/formamidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5147 | - | 1e-178 | 88.13% (337) | acetamidase/formamidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0587 | - | 2e-15 | 26.11% (314) | acetamidase/formamidase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4381 | - | 1e-175 | 86.65% (337) | amidase |
| M. thermoresistible (build 8) | TH_0852 | - | 2e-21 | 30.66% (274) | acetamidase/Formamidase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1186|M.vanbaalenii_PYR-1 ---------------------------------------MDHVTFVPSPD
Mflv_5147|M.gilvum_PYR-GCK ---------------------------------------MEHVTFIPTPD
MSMEG_4381|M.smegmatis_MC2_155 ---------------------------------------MDHITFVPTVD
TH_0852|M.thermoresistible__bu LSAGAGIATTLGACSSRSTVRATGASTDFEILQPGQGEITGDHYLQSVPD
MAB_0587|M.abscessus_ATCC_1997 ---------------------------------MPEVLFPLDSNKKFTEQ
. :
Mvan_1186|M.vanbaalenii_PYR-1 QFSFTFG---GAEPVMRIRPGTVLTLWTEDAYGGR---------------
Mflv_5147|M.gilvum_PYR-GCK QYRYTFG---GAAPVMRIKPQTVLTLWAEDAYGGR---------------
MSMEG_4381|M.smegmatis_MC2_155 QMNYTFG---GADPVMRIKPGTVLTLWTEDAYGGR---------------
TH_0852|M.thermoresistible__bu QVLWGYVPTVHATPVMQMRSGQTVTIDTVSHEGILEDQGRNPVEYFGAEG
MAB_0587|M.abscessus_ATCC_1997 QIIGHNRWHPDIPPAAVVKPGTSFRVHCREWFDGAIHN------------
* *. ::. . : . .
Mvan_1186|M.vanbaalenii_PYR-1 ------------ITSTDSVATTALDTEDLNPQTGPFWIEGAEPGDTLAVH
Mflv_5147|M.gilvum_PYR-GCK ------------ITSADDVASAVLDTPDLNPQTGPFHVEGAEPGDTLAIH
MSMEG_4381|M.smegmatis_MC2_155 ------------ITSVDSVAGTALDTEDLNPQTGPFFIEGAEPGDTLAVH
TH_0852|M.thermoresistible__bu VDENDVLEDVIAVAAEYDRTPRDFDKDGPHVVTGPIFIEGAEPGDVLKIE
MAB_0587|M.abscessus_ATCC_1997 ------------DDSADDIRDAPLTT--VHALSGPFSVEGAQPGDLLIVD
: . : . : :**: :***:*** * :.
Mvan_1186|M.vanbaalenii_PYR-1 LVDLTPARS----------WGASTLIPFFGGLTS-----VPVSPTLQDAL
Mflv_5147|M.gilvum_PYR-GCK LVDLTPART----------WGASTLIPFFGGLTS-----VPVSPTLQDPL
MSMEG_4381|M.smegmatis_MC2_155 LVDLTPART----------WGASTLIPFFGGLTS-----IPVSPTLQEPL
TH_0852|M.thermoresistible__bu TLEATPRVP----------YGVVSSRHGKGALALTADGTPPAGITLDEVM
MAB_0587|M.abscessus_ATCC_1997 ILDVGPIPQEDSGPLAGQGWGYTGIFPTVNGGGFLTEQFPDAYKAIWDFS
:: * :* .. . :: :
Mvan_1186|M.vanbaalenii_PYR-1 P--------------------------ERTWIYEYDSAAKTLAFDARGSD
Mflv_5147|M.gilvum_PYR-GCK P--------------------------ERTWIYEYDSAAETLAFNAHGSD
MSMEG_4381|M.smegmatis_MC2_155 P--------------------------ERTWIYEYDPATHTVGFAARGSD
TH_0852|M.thermoresistible__bu PPAVTDGRSN-------------PDPTRYGNLSTFTAVEDGHGVMSYG-D
MAB_0587|M.abscessus_ATCC_1997 GQTATSRHVPGVRFTGIVHPGLMGTAPSAELLARWNAREGALIATDPNRV
: : . .
Mvan_1186|M.vanbaalenii_PYR-1 FSVALPANPMLGTVGVAPARRE------VRTSLVPDVFGGNMDTPEMAAG
Mflv_5147|M.gilvum_PYR-GCK FSVALPANPMLGTVGVAPDRRE------VRTALVPDIFGGNMDTPEMAAG
MSMEG_4381|M.smegmatis_MC2_155 FEVALPANPMLGTVGVAPARRE------VRTSLVPDAFGGNMDTPEMTAG
TH_0852|M.thermoresistible__bu ARVRFPLAPFMGIMGVAFAQDRD-PTAPTANSVPPTIAGGNIDIRLLGEG
MAB_0587|M.abscessus_ATCC_1997 PALALPPEPRDAVLGALSGDSFDRAAAEAARTAPPRENGGNQDIKNLTKG
: :* * . :*. . : * *** * : *
Mvan_1186|M.vanbaalenii_PYR-1 ATCYLRVNVPGALFSLGDGHYRQGEGESCGT-AVEGAMHVTAIVDLIKSG
Mflv_5147|M.gilvum_PYR-GCK ATCYLRVNVPGALFSLGDGHYRQGEGESCGT-AVEGAMHVTAIVDLIKGG
MSMEG_4381|M.smegmatis_MC2_155 ATCYLRVNVEGALFSLGDGHYRQGEGEACGT-AVEGAMNVTAIVELIKGG
TH_0852|M.thermoresistible__bu STLYLPVFAEGALFYVGDPHMAMGDGEVALT-AMEGSLRGTYRLTVCKPG
MAB_0587|M.abscessus_ATCC_1997 SRVFYPVFVPGGKLSVGDLHFSQGDGEITFCGAIEMGGFIDLHVDVIKGG
: : * . *. : :** * *:** *:* . : : * *
Mvan_1186|M.vanbaalenii_PYR-1 GP--------AWPRLETD---THLMCVGSGRP----------LEEAWRAG
Mflv_5147|M.gilvum_PYR-GCK NS--------AWPRLETD---THLMCVGSGRP----------MEEAWRAS
MSMEG_4381|M.smegmatis_MC2_155 GP--------AWPRLETD---THLMAIGSGRP----------LEEAWRAS
TH_0852|M.thermoresistible__bu SGDAPSVA-YHYPFAETG---DAWVPIGLSDPDGSVGGQGTDLDVAMRRA
MAB_0587|M.abscessus_ATCC_1997 MDTYGVFENAIFMPGNTDPQYSQWLAFSGTSVTLDDEQRYLDSHLAYQRA
: :*. : .. . * : .
Mvan_1186|M.vanbaalenii_PYR-1 QVEMITWLGELYGLDRLDAYQLLTQISLAP-IANVVDTNYSSVTKIDKRL
Mflv_5147|M.gilvum_PYR-GCK QVEMITWLGELYGLDRYDAYQLLTQISLCP-IANVVDTNYSTVTKIDKRL
MSMEG_4381|M.smegmatis_MC2_155 QVEMITWLGELYGLDKYDAYQLLTQIALNP-IANVVDANYSTLTKIDKRL
TH_0852|M.thermoresistible__bu VANALDFLENDRGMDRATAYAYLSAASHFA-ISQVVDRTVGVHGQIFKSH
MAB_0587|M.abscessus_ATCC_1997 CLHAIDYLTK-FGYSPEQAYLLLGAAPIEGRLSGVVDIPNSCATVYIPTA
. : :* : * . ** * . :: *** .
Mvan_1186|M.vanbaalenii_PYR-1 LPAAPAYQGIHAELRSAAAALGTVNY--
Mflv_5147|M.gilvum_PYR-GCK LPTAPAYGGLHSELRSAAAALGSVNY--
MSMEG_4381|M.smegmatis_MC2_155 LPPAPAYGGIHAELRSAGRALGTISY--
TH_0852|M.thermoresistible__bu FAA-------------------------
MAB_0587|M.abscessus_ATCC_1997 IFDFPVTPTASGPVRIDPGPGAPRSVAR
: