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PVVEFTPSRDQYVWTFGGAEPVMEVAPGTALRLWTEDAFAGRVTSPTDRPSQVLNPKELNPQTGPFYVTG AEPGDTLALHFASIEPARSWAASTTIPLFGALTGTDRTATLQSPLPELTWIYDVDVERAVATFVAHESDF TLELPLAPMLGTVGVAPALREVRTTLVPDYFGGNMDTPELRAGTTVYLGVNVDGALFSVGDGHYRQGEGE TCGTALEGAMNVTVIVDLIKGGAPAWPRFEHDDALITVGSARPLEDAWRCSQVEMVGWMTELYGLGRMDA YQLCSQLCLSPLANVVDVNYSAVTKLYKQPLPGVEPYGGVHARLRERAAAL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0644 | - | - | 100% (332) | acetamidase/formamidase |
| M. vanbaalenii PYR-1 | Mvan_1186 | - | e-123 | 63.86% (332) | acetamidase/formamidase |
| M. vanbaalenii PYR-1 | Mvan_0290 | - | 2e-20 | 27.95% (254) | acetamidase/formamidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5147 | - | 1e-123 | 64.16% (332) | acetamidase/formamidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0587 | - | 7e-12 | 26.13% (333) | acetamidase/formamidase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4381 | - | 1e-122 | 62.35% (332) | amidase |
| M. thermoresistible (build 8) | TH_0852 | - | 3e-19 | 28.85% (312) | acetamidase/Formamidase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5147|M.gilvum_PYR-GCK ---------------------------------------MEHVTFIP---
MSMEG_4381|M.smegmatis_MC2_155 ---------------------------------------MDHITFVP---
Mvan_0644|M.vanbaalenii_PYR-1 ---------------------------------------MPVVEFTP---
TH_0852|M.thermoresistible__bu LSAGAGIATTLGACSSRSTVRATGASTDFEILQPGQGEITGDHYLQS---
MAB_0587|M.abscessus_ATCC_1997 ---------------------------------------MPEVLFPLDSN
:
Mflv_5147|M.gilvum_PYR-GCK ---TPDQYRYTFG---GAAPVMRIKPQTVLTLWAEDAYGGR---------
MSMEG_4381|M.smegmatis_MC2_155 ---TVDQMNYTFG---GADPVMRIKPGTVLTLWTEDAYGGR---------
Mvan_0644|M.vanbaalenii_PYR-1 ---SRDQYVWTFG---GAEPVMEVAPGTALRLWTEDAFAGR---------
TH_0852|M.thermoresistible__bu ---VPDQVLWGYVPTVHATPVMQMRSGQTVTIDTVSHEGILEDQGRNPVE
MAB_0587|M.abscessus_ATCC_1997 KKFTEQQIIGHNRWHPDIPPAAVVKPGTSFRVHCREWFDGAIHN------
:* *. : . . : .
Mflv_5147|M.gilvum_PYR-GCK ------------------ITSADDVASAVLDTPDLNPQTGPFHVEGAEPG
MSMEG_4381|M.smegmatis_MC2_155 ------------------ITSVDSVAGTALDTEDLNPQTGPFFIEGAEPG
Mvan_0644|M.vanbaalenii_PYR-1 ------------------VTSPTDRPSQVLNPKELNPQTGPFYVTGAEPG
TH_0852|M.thermoresistible__bu YFGAEGVDENDVLEDVIAVAAEYDRTPRDFDKDGPHVVTGPIFIEGAEPG
MAB_0587|M.abscessus_ATCC_1997 ------------------DDSADDIRDAPLTT--VHALSGPFSVEGAQPG
: . : : :**: : **:**
Mflv_5147|M.gilvum_PYR-GCK DTLAIHLVDLTPARTWGASTLIPFFGGLTS-----VPVSPTLQDPLP---
MSMEG_4381|M.smegmatis_MC2_155 DTLAVHLVDLTPARTWGASTLIPFFGGLTS-----IPVSPTLQEPLP---
Mvan_0644|M.vanbaalenii_PYR-1 DTLALHFASIEPARSWAASTTIPLFGALTG-----TDRTATLQSPLP---
TH_0852|M.thermoresistible__bu DVLKIETLEATPRVPYGVVSSRHGKGALALTADGTPPAGITLDEVMPPAV
MAB_0587|M.abscessus_ATCC_1997 DLLIVDILDVGPIPQEDSGPLAGQGWGYTG-IFPTVNGGGFLTEQFP-DA
* * :. . * . . : * . :*
Mflv_5147|M.gilvum_PYR-GCK -ERTWIYE-------------------------YDSAAETLAFNAHGS--
MSMEG_4381|M.smegmatis_MC2_155 -ERTWIYE-------------------------YDPATHTVGFAARGS--
Mvan_0644|M.vanbaalenii_PYR-1 -ELTWIYD-------------------------VDVERAVATFVAHES--
TH_0852|M.thermoresistible__bu TDGRSNPD-------------------------PTRYGNLSTFTAVEDGH
MAB_0587|M.abscessus_ATCC_1997 YKAIWDFSGQTATSRHVPGVRFTGIVHPGLMGTAPSAELLARWNAREGAL
. . : * .
Mflv_5147|M.gilvum_PYR-GCK -------DFSVALPANPMLGTVGVAPDRRE------VRTALVPDIFGGNM
MSMEG_4381|M.smegmatis_MC2_155 -------DFEVALPANPMLGTVGVAPARRE------VRTSLVPDAFGGNM
Mvan_0644|M.vanbaalenii_PYR-1 -------DFTLELPLAPMLGTVGVAPALRE------VRTTLVPDYFGGNM
TH_0852|M.thermoresistible__bu GVMS-YGDARVRFPLAPFMGIMGVAFAQDRD-PTAPTANSVPPTIAGGNI
MAB_0587|M.abscessus_ATCC_1997 IATDPNRVPALALPPEPRDAVLGALSGDSFDRAAAEAARTAPPRENGGNQ
: :* * . :*. . : * ***
Mflv_5147|M.gilvum_PYR-GCK DTPEMAAGATCYLRVNVPGALFSLGDGHYRQGEGESCGT-AVEGAMHVTA
MSMEG_4381|M.smegmatis_MC2_155 DTPEMTAGATCYLRVNVEGALFSLGDGHYRQGEGEACGT-AVEGAMNVTA
Mvan_0644|M.vanbaalenii_PYR-1 DTPELRAGTTVYLGVNVDGALFSVGDGHYRQGEGETCGT-ALEGAMNVTV
TH_0852|M.thermoresistible__bu DIRLLGEGSTLYLPVFAEGALFYVGDPHMAMGDGEVALT-AMEGSLRGTY
MAB_0587|M.abscessus_ATCC_1997 DIKNLTKGSRVFYPVFVPGGKLSVGDLHFSQGDGEITFCGAIEMGGFIDL
* : *: : * . *. : :** * *:** *:* .
Mflv_5147|M.gilvum_PYR-GCK IVDLIKGGNS-------AWPRLETDT----HLMCVGSGRP----------
MSMEG_4381|M.smegmatis_MC2_155 IVELIKGGGP-------AWPRLETDT----HLMAIGSGRP----------
Mvan_0644|M.vanbaalenii_PYR-1 IVDLIKGGAP-------AWPRFEHDD----ALITVGSARP----------
TH_0852|M.thermoresistible__bu RLTVCKPGSGDAPSVAYHYPFAETGD----AWVPIGLSDPDGSVGGQGTD
MAB_0587|M.abscessus_ATCC_1997 HVDVIKGGMDTYGVFENAIFMPGNTDPQYSQWLAFSGTSVTLDDEQRYLD
: : * * : ..
Mflv_5147|M.gilvum_PYR-GCK MEEAWRASQVEMITWLGELYGLDRYDAYQLLTQISLC-PIANVVDTNYST
MSMEG_4381|M.smegmatis_MC2_155 LEEAWRASQVEMITWLGELYGLDKYDAYQLLTQIALN-PIANVVDANYST
Mvan_0644|M.vanbaalenii_PYR-1 LEDAWRCSQVEMVGWMTELYGLGRMDAYQLCSQLCLS-PLANVVDVNYSA
TH_0852|M.thermoresistible__bu LDVAMRRAVANALDFLENDRGMDRATAYAYLSAASHF-AISQVVDRTVGV
MAB_0587|M.abscessus_ATCC_1997 SHLAYQRACLHAIDYLTK-FGYSPEQAYLLLGAAPIEGRLSGVVDIPNSC
. * : : . : :: : * . ** :: *** .
Mflv_5147|M.gilvum_PYR-GCK VTKIDKRLLPTAPAYGGLHSELRSAAAALGSVNY--
MSMEG_4381|M.smegmatis_MC2_155 LTKIDKRLLPPAPAYGGIHAELRSAGRALGTISY--
Mvan_0644|M.vanbaalenii_PYR-1 VTKLYKQPLPGVEPYGGVHARLRERAAAL-------
TH_0852|M.thermoresistible__bu HGQIFKSHFAA-------------------------
MAB_0587|M.abscessus_ATCC_1997 ATVYIPTAIFDFPVTPTASGPVRIDPGPGAPRSVAR
: