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MDTVQREALASLRLTWAPTSDDLWRPQGATHVTGLNEHAVDDVMDAFGDALADPASTPLGVVIRGPAGSG KTHLLGQIRERVQDGGGFFFVVELLDAASFWESVRSGMLESLGRPGANRETQLKDLLWELASLAHVSRAD RRAIIGDDDLDPETLYRFIKALSSAAKETVRQCHQVLRALVLLGSNDFVAHDIGEGFLEGTEEFTVEERG PWGLRSAPASAQECVRDLSRLVALAGPSVLAVDQIDTLIAQSVAATGQSTGDGGIVLEQVAHGLMALRQT MRRTVTAVACLPAVWEHIRDQAGAAVADRFRVTGVLTPLPSADIGRAILERRFAASYAATGFTPLYPSWP LAPEAFEEAPSYTPRQLLIRADTHVRECLKHGTVVELTHLRADAQPTWETQSPNGNAPVSGALDRRFAEY RRRAVPEAALAHDGEDTTMPELLSAALTAWIAERDGEQTFVCDPPPGAHVVLHARLRESLDSATDDERHW AFRAVAATNATAALSRIRKAVTAAGFGAGSDRRSLFLLRNSPWPSGPKTAAVIDEFLAAGGRVLPLSDDD VRTMTALRDLIRDDDPDLPGWLRARRPAHGLTLLAEALGDGPAEPVAVVPEDGPEAALPVDEPESVVDHD YEVPDTELPLGLDVHTEEPVTVGLSALRKHVAIFAGSGSGKTVLIRRLVEECALRGVSSIVLDPNNDLSR LGTGWPQPPDGWRRSDGARADDYLRHTEVTIWTPRRTNGRPLAFQPLPDFASVVADYDEFTDAVESACAA LEPQALITGKTQKATRSRAVLREALQHYGRTPSPTLDGFVRLLADLPEDVSNMAGAHAIAGDLSQNLRAA MVNDPLFGGAGTPVDPGVLLTPSDGYRARVSVISMIGLPSDEQRQSFVNQLQMALFAWIKRNPAGERPLG GLLVMDEAQNFAPARGFTACTRSTLALSSQARKYGLGLVFATQAPKSLNNNIPGNAATQFYGLLNAPAQI EAAREMARAKGGLVDDISRLRAGNFYVAAEGEAFHRIVAPWCLSYHPSSPPSAEDVLELAISV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1183 | - | - | 100% (1043) | AAA ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5149 | - | 0.0 | 84.21% (1045) | AAA ATPase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1665 | - | 3e-05 | 22.99% (374) | ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3596 | - | 0.0 | 65.63% (1062) | ATPase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1183|M.vanbaalenii_PYR-1 MDTVQREALASLRLTWAPTSDDLWRPQGATHVTGLNEHAVDDVMDAFGDA
Mflv_5149|M.gilvum_PYR-GCK MDTLQREALASLRLTWAPTSDDLWRPQAATHVTGLNEHAVDDVMDAFGDA
MSMEG_3596|M.smegmatis_MC2_155 MQQHEREALSALRLTWAPTADDLWHSQGALHVPGLHERAMTDVLAAFDDA
MAV_1665|M.avium_104 -MSTDSAATPATRIADG--------YAVAGQALELGTVVIDGAADPSAQI
: * .: *:: . * :. * .: .. . :
Mvan_1183|M.vanbaalenii_PYR-1 LADPASTPLGVVIRGPAGSGKTHLLGQIRERVQDGGGFFFVVELLDAASF
Mflv_5149|M.gilvum_PYR-GCK LRDEASSPMGVVIRGSAGSGKTHLLGQVRERVQAGGGYFFVVELLDAASF
MSMEG_3596|M.smegmatis_MC2_155 ARETDSSPLGVVVRGPAGSGKTHLLGQVRERVQTAGGFFFLVELLDATSF
MAV_1665|M.avium_104 RIPLATVNRHGLVAGATGTGKTKTLQLIAEQLSAAG-----------VPV
: :: *.:*:***: * : *::. .* ...
Mvan_1183|M.vanbaalenii_PYR-1 WESVRSGMLESLGRPGANRETQLKDLLWELASLAHVSRADRRAIIGDDDL
Mflv_5149|M.gilvum_PYR-GCK WQSVRSGVLESLGRPGTQRETQLKDLLWELSSLAHVSRADRRAIIGDDDL
MSMEG_3596|M.smegmatis_MC2_155 WQSARAGILESLGRPGGERETQLKDLLWELASIAHISRANRRAIIGDDDL
MAV_1665|M.avium_104 LMADVKGDLSGLSRPGQGD-----------------DRTAARAKDTGDDW
: * *..*.*** .*: ** .**
Mvan_1183|M.vanbaalenii_PYR-1 DPETLYRFIKALSSAAKETVRQCHQVLRALVLLGSNDFVAHDIGEGFLE-
Mflv_5149|M.gilvum_PYR-GCK DAETLYRFIKALSGVAKETVRQCHQVLRALVLLASNDFIAHDIGEGFLQ-
MSMEG_3596|M.smegmatis_MC2_155 TPEILTDFVTALHKARRQTVKRAHHTLRALVLLGAADLDLQDIGEAFLVG
MAV_1665|M.avium_104 QATAFP--------------------------------------------
. :
Mvan_1183|M.vanbaalenii_PYR-1 -----GTEEFTVEERGPWGLRSAPASAQECVRDLSRLVALAGPSVLAVDQ
Mflv_5149|M.gilvum_PYR-GCK -----GSDEFSIAERGPWGLRSAPESAQMCVRDIVRLVALAGPAVLAVDQ
MSMEG_3596|M.smegmatis_MC2_155 NVGTLGATDGSEAELAAWGLPVPTLTPQESVRDISRLVALAGPAVLALDQ
MAV_1665|M.avium_104 --------------------------------------------------
Mvan_1183|M.vanbaalenii_PYR-1 IDTLIAQSVAATGQ-STGDGG-------IVLEQVAHGLMALRQTMRRTVT
Mflv_5149|M.gilvum_PYR-GCK IDTLLAQSLAGT----DGDG---------VLEQVAHGLMALRQTTRRTVP
MSMEG_3596|M.smegmatis_MC2_155 IDTLLAQSIERTADRVSGENSEPASLDNRDLEHVAHGLMSVRQTMRRTVS
MAV_1665|M.avium_104 ------------------------------VEFLSLGTNGIGVPIRATVE
:* :: * .: . * **
Mvan_1183|M.vanbaalenii_PYR-1 AVACLPAVWEHIRDQAGAAVADRFRVTGVLTPLPSADIGRAILERRFAAS
Mflv_5149|M.gilvum_PYR-GCK VVACLPAVWEHIQDRAAASVADRFRVTGMLTPLPSADIGRAILERRFAAS
MSMEG_3596|M.smegmatis_MC2_155 VVACLPAAWEAIENRATASVHDRFRTTALLQGLPTPDIGRAILERRFSAT
MAV_1665|M.avium_104 SFG-----------------------------------------------
..
Mvan_1183|M.vanbaalenii_PYR-1 YAATGFTPLYPSWPLAPEAFEEAPSYTPRQLLIRADTHVRECLKHGTVVE
Mflv_5149|M.gilvum_PYR-GCK YRAVGFDPPYPSWPLAPSAFEEAPSYTPRQLLIRADTHVRECLKRGEVVE
MSMEG_3596|M.smegmatis_MC2_155 YSAVGFSAPYPSWPILPSAFDDATQYTPRQLLKRADAHVRHCLEHDTVEE
MAV_1665|M.avium_104 --------------------------------------------------
Mvan_1183|M.vanbaalenii_PYR-1 LTHLRADAQPTWETQSPNGNAPVSGALDRRFAEYRRRAVPEAALAHDGED
Mflv_5149|M.gilvum_PYR-GCK LAHLRADAQPDWDTVSTNGSGAVSTALDRRFAEYRRRAVPAAAVAHDGED
MSMEG_3596|M.smegmatis_MC2_155 LTRLTGEVDTTHGPGHAGGTRTDTSELDRRFAEYRSRAVTAAALDPDGED
MAV_1665|M.avium_104 --------------------------------------------------
Mvan_1183|M.vanbaalenii_PYR-1 TTMPELLSAALTAWIAER-DGEQTFVCDPPPGAHVVLHARLRESLDSATD
Mflv_5149|M.gilvum_PYR-GCK VTVPELLSAALTAWIAER-DGEATFVCDPPPGTHVMLHARLRETLDSATD
MSMEG_3596|M.smegmatis_MC2_155 TTMPGLLSAALEAWITELGEVEQTFWPDPPPGQRVVLHARLRQSLDAATD
MAV_1665|M.avium_104 ---PVLLSKVLGLNATQESTLGLIFHWAKERNWPLVTTDNLRGAISHLTS
* *** .* :: * . :: .** ::. *.
Mvan_1183|M.vanbaalenii_PYR-1 DERHWAFRAVAATNATAALSRIRKAVTAAGFGAGSDRRSLFLLRNSPWPS
Mflv_5149|M.gilvum_PYR-GCK DERHWAFRAVAGTNASAVLSRVRKALTASGFGSGGDRRRLFLLRNSPWPS
MSMEG_3596|M.smegmatis_MC2_155 DERHWAFRAVASGNAIAVQNRIRKALEATGLNP--ERRTLFLLRNTPWPR
MAV_1665|M.avium_104 DEGKEDLKSLGGVSATTAGVILRALVNLDAEGGDTFFGEPKLDPNDLLRT
** : ::::.. .* :. :* : . . * *
Mvan_1183|M.vanbaalenii_PYR-1 GPKTAAVIDEFLAAGGRVLPLSDDDVRTMTALRDLIRDDDPDLPGWLRAR
Mflv_5149|M.gilvum_PYR-GCK GKKTTEEIELFHSAGGRTLPLSDDDIRTMTALRDLFADDDPELAAWLRAR
MSMEG_3596|M.smegmatis_MC2_155 GAKTAAMVDEFTAAGGRVLPMSDDDIRTMTALRDLIDDNHPDLPGWLRRR
MAV_1665|M.avium_104 NDQGQGVISLLEFTGQSVRPVIFS-----TFLMWLLADLYTQLPEVGDID
. : :. : :* . *: . * * *: * .:*.
Mvan_1183|M.vanbaalenii_PYR-1 RPAHGLTLLAEALGDGP------AEPVAVVPEDGPEA-ALPVDEPESVVD
Mflv_5149|M.gilvum_PYR-GCK RPAHGLTLLREALGGDS------ESAEPAAPEPEP--------DPEDEVV
MSMEG_3596|M.smegmatis_MC2_155 RPAHAIDLLRAALGDVAGEAPDLEATDPRMPIELPSAGSEFVPQPDPAPA
MAV_1665|M.avium_104 KPKLVFFFDEAHLLFAD---------------------------------
:* : : *
Mvan_1183|M.vanbaalenii_PYR-1 HDYEVPDTELPLGLDVHTEEPVTVGLSALRKHVAIFAGSGSGKTVLIRRL
Mflv_5149|M.gilvum_PYR-GCK ADYDVPADEIPLGLDLQDEKPVTVQLSALRKHVAIFAGSGSGKTVLIRRL
MSMEG_3596|M.smegmatis_MC2_155 VAIEHSPTAITLGVDATGGQPVSVDLAALRKHTAIFAGSGSGKTVLIRRL
MAV_1665|M.avium_104 --------------------ASKAFLEQVEQTVKLIRSKGVG--------
. .. * :.: . :: ..* *
Mvan_1183|M.vanbaalenii_PYR-1 VEECALRGVSSIVLDPNNDLSRLGTGWPQPPDGWRRSDGARADDYLRHTE
Mflv_5149|M.gilvum_PYR-GCK VEECALRGVSSIVLDPNNDLSRLGTAWPQTPAGWRRGDDARADDYLTNTE
MSMEG_3596|M.smegmatis_MC2_155 VEECALRGVSSIVLDPNNDLSRLGSRWPESPPGWNPADHERSDEYFANTE
MAV_1665|M.avium_104 ----VFFCTQLPTDIPNDVLSQLGARIQHALRAFTPDD------------
.: .. . **: **:**: .. .: *
Mvan_1183|M.vanbaalenii_PYR-1 VTIWTPRRTNGRPLAFQPLPDFASVVADYDEFTDAVESACAALEPQALIT
Mflv_5149|M.gilvum_PYR-GCK VTVWTPRRTNGRPLAFAPLPDFAGVLDDPDEFTEAVEAACSALEPQALIT
MSMEG_3596|M.smegmatis_MC2_155 VVVWTPRRATGRPLSFQPLPDFASVLDDDDEFSDAVESAVAALEPRALIV
MAV_1665|M.avium_104 --------------------------------------------------
Mvan_1183|M.vanbaalenii_PYR-1 GKTQKATRSRAVLREALQHYGRTPSPTLDGFVRLLADLPEDVSNMAGAHA
Mflv_5149|M.gilvum_PYR-GCK GKTQKATRSRAVLREALQHYGKTESPTLGGFIRLLADLPEDVSDIAGAHA
MSMEG_3596|M.smegmatis_MC2_155 GNTAKANRSRAVLREALRYYGASRSVTLSGFIDLLGDLPDDVSALGNARA
MAV_1665|M.avium_104 ---------QKALSKTVRTYPKTD----------VYDLESALTSLGIGEA
: .* :::: * : : ** . :: :. ..*
Mvan_1183|M.vanbaalenii_PYR-1 IAGDLSQNLRAAMVNDPLFGGAGTPVDPGVLLTPSDGYRARVSVISMIGL
Mflv_5149|M.gilvum_PYR-GCK IAGDLSQNLRAAMVNDPMFGGAGTPVDPGVLLTPSDGYRARVSVISMIGL
MSMEG_3596|M.smegmatis_MC2_155 LAAELGQNLRAATVNDPLFGGAGTAADPGVLLTPSAGYRARVSVISMVGL
MAV_1665|M.avium_104 VVTVLSE------------KGAPTPVAWTRMRVP----RSLMASIGTEEI
:. *.: ** *.. : .* *: :: *. :
Mvan_1183|M.vanbaalenii_PYR-1 PSDEQRQSFVNQLQMALFAWIKRNPAGERPLGGLLVMDEAQNFAPARGFT
Mflv_5149|M.gilvum_PYR-GCK PSDDQRQSFVNQLQMALFAWIKRNPAGDRPLGGLLVMDEAQNFAPARGFT
MSMEG_3596|M.smegmatis_MC2_155 TNEQQREGFVNQLQMALFAWIKRNPAGNRPLGGLLVMDEAQNFAPSSHTT
MAV_1665|M.avium_104 TKAAKRSELQAKYGQTVQQPAQPPPGPQAPTG------------------
.. :*. : : :: : *. : * *
Mvan_1183|M.vanbaalenii_PYR-1 ACTRSTLALSSQARKYGLGLVFATQAPKSLNNNIPGNAATQFYGLLNAPA
Mflv_5149|M.gilvum_PYR-GCK ACTRSTLALSSQARKYGLGLVFATQAPKGLNLNIPGNAATQFYGLLNAPA
MSMEG_3596|M.smegmatis_MC2_155 ASTHSTLALSSQARKYGLGLVFATQSPRGLHNHIPGNSATQFYGLLNSPA
MAV_1665|M.avium_104 --SRSPQAQS----------DYPPVPPNGPVPPMPEPAEPKGPGLLER--
::*. * * :.. .*.. :* : .: ***:
Mvan_1183|M.vanbaalenii_PYR-1 QIEAAREMARAKGGLVDDISRLRAGNFYVAAEGEAFHRIVAPWCLSYHPS
Mflv_5149|M.gilvum_PYR-GCK QIETAREMARAKGGLVDDISRLRAGNFYVATEGESFHRIVAPWCLSHHPA
MSMEG_3596|M.smegmatis_MC2_155 QIAVAREMARVKGGLVPDISRLRSGQFYLALEGNAFHKIQTPWCLSHHPP
MAV_1665|M.avium_104 -LWHDRDVQSAVNTGIREIIRLKFG-------GGGRRRK-----------
: *:: . . : :* **: * * . ::
Mvan_1183|M.vanbaalenii_PYR-1 SPPSAEDVLELAISV-----
Mflv_5149|M.gilvum_PYR-GCK SPPSAEEVLNLATSV-----
MSMEG_3596|M.smegmatis_MC2_155 SPPTTDEVLRLAQQREPAAP
MAV_1665|M.avium_104 --------------------