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M. vanbaalenii PYR-1 Mvan_1179 (-)

annotation: threonine aldolase
coordinates: 1254524 - 1255555
length: 343

ERVPSAAFASDNAAPAHPRVLEALHHVNQGPAPSYGDDPVTAEAAEALRTAFESPGADVLFAFTGTAANI
IALASAVRPWHEIFCSDVAHVLVDEAGGPVRLSGAQLTRLASDDGLISPDELERRVRGRSAVHHSQPRIV
SITQSTENGRVWSATAVAQFVDRAHALGLLVHVDGARIANAVAALSISPLEAIGDADIVSVGGTKNGLMF
GDAILVRRPAHFDGIHFVQKQIGHLASKHRFVAAQFAGLFEGGLWLRNAAHANAMARRLSTGLEALGLQL
ASPTESNEVFVKLDGEAHRRLAERYLVHQPDPGQPVVRFVCSWSTTETEVDDALAALRSAGN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1179--100% (343)threonine aldolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_5153-1e-14283.50% (297) threonine aldolase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_4454ltaE1e-12967.46% (335) L-threonine aldolase, low-specificity
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_1179|M.vanbaalenii_PYR-1       MERVPSAAFASDNAAPAHPRVLEALHHVNQGPAPSYGDDPVTAEAAEALR
Mflv_5153|M.gilvum_PYR-GCK          ---MPSAAFASDNAAPAHPSVLDALHRANDGSAPSYGDDAVTAQAADAIR
MSMEG_4454|M.smegmatis_MC2_155      ---MPSSAFASDNAAPAHPNVLDAITAANTGAAPSYGADPITQRAVAALR
                                       :**:************ **:*:  .* *.***** *.:* .*. *:*

Mvan_1179|M.vanbaalenii_PYR-1       TAFESPGADVLFAFTGTAANIIALASAVRPWHEIFCSDVAHVLVDEAGGP
Mflv_5153|M.gilvum_PYR-GCK          TAFDSPGADVLFAFTGTAANTIALASATRPWHEIFCSDVAHVLVDEAGGP
MSMEG_4454|M.smegmatis_MC2_155      TAFDSPDAEVLFALTGTGANVIALAASVRPWQSILCSDIAHSLVDEAGGP
                                    ***:**.*:****:***.** ****::.***:.*:***:** ********

Mvan_1179|M.vanbaalenii_PYR-1       VRLSGAQLTRLASDDGLISPDELERRVRGRSAVHHSQPRIVSITQSTENG
Mflv_5153|M.gilvum_PYR-GCK          VRLSGAQLTRLPSVDGLIAPEDLERRVRGRGAVHHSQPRIVSITQSTESG
MSMEG_4454|M.smegmatis_MC2_155      VRLSGAQLTVLPSDDGLIDAAVLDDAVVRRGDVHASQPAVVTITQSTENG
                                    ********* *.* **** .  *:  *  *. ** *** :*:******.*

Mvan_1179|M.vanbaalenii_PYR-1       RVWSATAVAQFVDRAHALGLLVHVDGARIANAVAALSISPLEAIGDADIV
Mflv_5153|M.gilvum_PYR-GCK          RVWTTDAVADFVDHAHALGLLVHVDGARIANAVAALGVSPVEAIADADIV
MSMEG_4454|M.smegmatis_MC2_155      RVWTPQTIKDFIDHAHDLGLLVHVDGARVANAVAALDVAPREAVGDADIV
                                    ***:. :: :*:*:** ***********:*******.::* **:.*****

Mvan_1179|M.vanbaalenii_PYR-1       SVGGTKNGLMFGDAILVRRPAHFDGIHFVQKQIGHLASKHRFVAAQFAGL
Mflv_5153|M.gilvum_PYR-GCK          SIGGTKNGLLFGDAILVRRPEHFDGIHWVQKQIGHLASKHRFIAAQFVAL
MSMEG_4454|M.smegmatis_MC2_155      TVGGTKNGLLMGDALLVRRPELFEGIHFAQKQIGHLSSKQRFIAAQFEAM
                                    ::*******::***:*****  *:***:.*******:**:**:**** .:

Mvan_1179|M.vanbaalenii_PYR-1       FEGGLWLRNAAHANAMARRLSTGLEALGLQLASPTESNEVFVKLDGEAHR
Mflv_5153|M.gilvum_PYR-GCK          FGDGLWLRNAEHANAMARRLSAGLQSLGYQLASPAESNEVFVQIDGDCAR
MSMEG_4454|M.smegmatis_MC2_155      LRDDLWLRNAAHANAMAARLSSGMTERGLTLASPTDANEVFVNLPAATFA
                                    : ..****** ****** ***:*:   *  ****:::*****:: .    

Mvan_1179|M.vanbaalenii_PYR-1       R-----------------LAERYLVHQPDPGQP-------VVRF------
Mflv_5153|M.gilvum_PYR-GCK          APDAGLSGPPARPQPACGAVRDVLGHHGGRGRRRPGRVDNVARVGAPRAR
MSMEG_4454|M.smegmatis_MC2_155      A-----------------VSERYAVHRLDPRHP-------AVRF------
                                                        .    *: .  :        ..*.      

Mvan_1179|M.vanbaalenii_PYR-1       VCSWSTTETEVDDALAALRSAGN----
Mflv_5153|M.gilvum_PYR-GCK          VSARPSPACHADSPHARRGTTAPIVTP
MSMEG_4454|M.smegmatis_MC2_155      VCSWATTDQEVDDVLALLGQL------
                                    *.: .:.  ..*.  *