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MTESRCDATQPGAGYRLQYAEVYNWGTFDDHSWRFTPGTDTALLTGDIGSGKSTIVDALTTLLVPAHKAA YNKAAGADAKERTLRSYVEGHYKSERNESTGRSRPKGLRENKRTYSVILGVFRNHGHDETVTLAQVFQQR ESTGQPYRFFVTATKELSIATDFADFGTDLRELRRRLRGAGAEIFDEFPKYSTSLRRLLGIRSEQALELF HQTVSMKSVGNLNDFVRDHMLEPSDSTERVREIIGHFEDLTKAHDAVKRAREQLEALQPIVDTAAKYDAA LAERAGLELERAAVRLFIAELRSGLLTDEIARLEADGAALLTQLDTAEAEQRRLGRERDSLIEERAKAGG DRIGELERLAADAREQAKTRSQTKALFDAAVAEAGLEPVADGDAFAALGAVVAGERPRLTGEKRDLDTAT VDAIGREREHQRRCDVIAEEVASLEQRTDNLPQEQVVVRAELCAALGLTPDDLPYAGELLDVHDEHAQWR GAAERVLRGFALSLLVPQRHYDAVTAWVNGRRLTVGGRGAKLVYERVPQHRVRLQPTAHDGLLLADCIEV RDGQFEEYLRAELMKRADFRCAATLDEFRTERRAVTREGQVRSGDRHEKDDRHRVDDPRRWVLGWVNERK IAAMRAELAELESQRDEAAAQAARLVKERDALQCRLDAFRSVEGFRSWGELDADEAESRAKAHDAERVRL QAGSNRLAEITQALERNAENAVTVTDLIKKLTGMLATAQSRMNQAKQERSRDDEFVAAHAPDQREKARAS YPALTARLADSPPARAADCADSEAALSDDLHRRIERLSGQLNGHALNLTQHMTAVLNRWQELRADMDVNV ESRADFLAFRERVATDDLPRFESEFKEQLNKNAIQELAGFNNWLGRQASAIDERVDRINDALGAVPYNPG RYIKLEKEPTSNQDVAQFRSDLRNLTNDTLTADGDQYSEQRFLDVKRIIERFRGRDGYAESDKNWTRRVT DVRNWFVFSASERDVDTDLEWEHYSDSDGKSGGQKEKLAYTILAASLAYQFGLEWGVERSRDFRFAVIDE AFGRGSDVSTRYALDLFATLGLQLLIVTPLQKVHVIEPYVKSIGIVDNPTGTYSRLQTMTIEEYRDRRDR PLR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1133 | - | - | 100% (1123) | hypothetical protein Mvan_1133 |
M. vanbaalenii PYR-1 | Mvan_1172 | - | 5e-75 | 25.18% (1140) | hypothetical protein Mvan_1172 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_5159 | - | 9e-78 | 26.11% (1145) | hypothetical protein Mflv_5159 |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1492 | - | 4e-81 | 25.88% (1132) | hypothetical protein MAB_1492 |
M. marinum M | MMAR_3068 | - | 1e-78 | 26.11% (1153) | hypothetical protein MMAR_3068 |
M. avium 104 | MAV_1428 | - | 1e-05 | 24.38% (644) | hypothetical protein MAV_1428 |
M. smegmatis MC2 155 | MSMEG_1281 | - | 0.0 | 81.80% (1077) | hypothetical protein MSMEG_1281 |
M. thermoresistible (build 8) | TH_2611 | - | 2e-83 | 26.48% (1148) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_2313 | - | 2e-77 | 25.94% (1145) | hypothetical protein MUL_2313 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_1133|M.vanbaalenii_PYR-1 MTESRCDATQPGAGYRLQYAEVYNWGTFDDHSWRFTPGTDTALLTGDIGS MSMEG_1281|M.smegmatis_MC2_155 ------------------------------------------MLTGDIGS MMAR_3068|M.marinum_M ----------MTEQFHLSRLQVINWGVFDGYHS-IPFSVGGALIAGASGS MUL_2313|M.ulcerans_Agy99 ----------MTEQFHLSRLQVINWGVFDGYHS-IPFSVGGALIAGASGS Mflv_5159|M.gilvum_PYR-GCK ----------MTEQFHLSRLQVINWGVFDGYHD-IPFSEGGALIAGASGS TH_2611|M.thermoresistible__bu ----------LTEQFHLSRLQVINWGVFDGYHS-IPFSPGGALIAGASGS MAB_1492|M.abscessus_ATCC_1997 ----MTTSDAATQQFWLSRLQVINWGVFDGYHS-IEFSRRGTLITGSSGS MAV_1428|M.avium_104 --------------MKLHRLTLTNYRGIAHREIEFPDHG-VVVVCGANEI :: * Mvan_1133|M.vanbaalenii_PYR-1 GKSTIVDALTTLLVPAHKAAYNK-----AAGADAKERTLRSYVEGHYKSE MSMEG_1281|M.smegmatis_MC2_155 GKSTIVDALTTLLVPSHKAAYNK-----AAGADAKERTLRSYVEGHYRSE MMAR_3068|M.marinum_M GKSSLLDAISLGFLPFNRRNFNASGDNTAAGSSAGRRTVDKYVRGAWG-Q MUL_2313|M.ulcerans_Agy99 GKSSLLDAISLGFLPFNRRNFNASGDNTAAGSSAGRRTVDKYVRGAWG-Q Mflv_5159|M.gilvum_PYR-GCK GKSSLLDAISLGFLPFNRRNFNASGDNTAAGSSAGRRTVDKYVRGAWG-Q TH_2611|M.thermoresistible__bu GKSSLLDAISLGFLPFNRRNFNASGDQTAAGSSAGRRTVDKYVRGAWG-Q MAB_1492|M.abscessus_ATCC_1997 GKSSLLDAISLAFLSSNRRNFNASSDTTAAGSSMGKRTVDKYVRGLWG-E MAV_1428|M.avium_104 GKSSMIEALDLLLEAKDRSTKKEVKQVKPTHSDVGAEVSAEISCGPYR-- ***::::*: : . .: : .: :. .. . * : Mvan_1133|M.vanbaalenii_PYR-1 RNESTGRSRPKGLRENKRTYSVILGVFRNHGHDETVTLAQVFQQRESTGQ MSMEG_1281|M.smegmatis_MC2_155 RNEATGKSRPKGLRENRRTYSVILGVFRNHGHDETVTLAQVFQQRESTGQ MMAR_3068|M.marinum_M RSD-GGTSRVMYLRGDGTAWSAVAVTYASDSGRTVTGLVLKWLTGESRND MUL_2313|M.ulcerans_Agy99 RSD-GGTSRVMYLRGDGTAWSAVAVTYASDSGRTVTGLVLKWLTGESRND Mflv_5159|M.gilvum_PYR-GCK RSD-GGTSRVMYLRGDGTAWSAVAVTYSSDSGRTVTGLVLKWLTGESRND TH_2611|M.thermoresistible__bu RSD-GGTNRVMYLRGEGTTWSAVAVTYTSDSGRTVTGLVLKWLTGESRSD MAB_1492|M.abscessus_ATCC_1997 LKNPGERPKQMFLRGKGGAWSAIAVTYSGTDGRVITGLVLKWLAPGSDSD MAV_1428|M.avium_104 -----FVYRKRFHKKCETELTVITPYREQLTGDEAHERVRAMLAETVDSD : : :.: . .: Mvan_1133|M.vanbaalenii_PYR-1 PYRFFVTATKELSIATDFADFGTDLRELRRRLRGAG------AEIFDEFP MSMEG_1281|M.smegmatis_MC2_155 PYRFFVTATKELSIAVDFADFGSDLRELRKRLRSAG------AEIFDEFP MMAR_3068|M.marinum_M SSSRFVLGDGDLDIEEVCNRWASGRFDAGVFKED-------WRFSTKVES MUL_2313|M.ulcerans_Agy99 SSSRFVLGDGDLDIEEVCNRWASGRFDAGVFKED-------WRFSTKVES Mflv_5159|M.gilvum_PYR-GCK SSSRFVLGDGDLDIEDICNRWAAGRFDTGVFKEGQGERSDGWRFTTKVES TH_2611|M.thermoresistible__bu SSSRFVIGDGDLDIEEVCNRWAARRFDASVFKEG------GWRFTTKVES MAB_1492|M.abscessus_ATCC_1997 SSSRYYLIDADADIRDLCNAWASKGYAGSVFEGAG------WRGH-KSER MAV_1428|M.avium_104 LWHAQRVLQAASTAAVDLSGCDALSRALDVAAGDSG-------GLCGTEP : Mvan_1133|M.vanbaalenii_PYR-1 KYSTSLRRLLGIR-SEQALELFHQTVSMKSVGNLNDFVRDHMLEPSDSTE MSMEG_1281|M.smegmatis_MC2_155 KYATSLRRLLGIR-SEQALELFHQTVSMKSVGNLNDFVRDHMLEPSDSTE MMAR_3068|M.marinum_M QYLAQLYAAIGIRASDAAQQLLGKAKSLKSVGGLEQFVREFMLDEPDSLA MUL_2313|M.ulcerans_Agy99 QYLAQLYAAIGIRASDAAQQLLGKAKSLKSVGGLEQFVREFMLDEPDSLA Mflv_5159|M.gilvum_PYR-GCK QYLAQLYATIGIRASDAAQQLLGKAKSLKSVGGLEQFVREFMLDEPESLT TH_2611|M.thermoresistible__bu QYLAQLYATIGIRASDAAQQLLGKAKSLKSVGGLEQFVREFMLDEPESLA MAB_1492|M.abscessus_ATCC_1997 WYLEQLYAAVGIQGSSAAQQLLGKAKSLKSVGGLEQFVREYMLDEPESMA MAV_1428|M.avium_104 LLIERIDAEYARYFTPTGRPTGEWAAAIARLADAEAAVAECAAAVAEVDE : . : . : :: :.. : * : .: Mvan_1133|M.vanbaalenii_PYR-1 RVREIIGHFEDLTKAHDAVKRAREQLEALQPIVDTAAKYDAALAERAGLE MSMEG_1281|M.smegmatis_MC2_155 RIREIISHFDDLTRAHDAVKRAREQLEALEPIADTAAKYDAALAERDGLE MMAR_3068|M.marinum_M RLPEALKQIDPLVEARELLAVAQKKRKILGDIEQIQQRYASESSDLGIID MUL_2313|M.ulcerans_Agy99 RLPEALKQIDPLVEARELLAVAQKKRKILGDIEQIQQRYASESSDLGIID Mflv_5159|M.gilvum_PYR-GCK RLPEALKQIDPLVEARELLAVAQKKRKILGDIEKIQQRYASESTDLGIID TH_2611|M.thermoresistible__bu RLPEALKQIDPLVEARELLAVAQRKRKILGDIEQIQQRYAAESSDLGIID MAB_1492|M.abscessus_ATCC_1997 AISEALGQITPLVDARAALAIAQRQRQTLGDIEQIQQTYASDAAQLATVD MAV_1428|M.avium_104 RVSRHAALTEQVADLSQRRIAAGPRVTAARQAADRIAELTAQRRE----- : . :. * : . : : Mvan_1133|M.vanbaalenii_PYR-1 LERA-AVRLFIAELRSGLLTDEIARLEADGAALLTQLDTAEAEQRRLGRE MSMEG_1281|M.smegmatis_MC2_155 HERS-AVRLFIAELRSGLLADEIGRLEADGAALWQQQDAAEADQRRLNHE MMAR_3068|M.marinum_M LVDAPMVRAYTDHARLAQCPAQIATLDGTVDQLENEYEDVTRSLNLAKAE MUL_2313|M.ulcerans_Agy99 LVDAPMVRAYTDHARLAQCPAQIATLDGTVDQLENEYEDVTRSLNLAKAE Mflv_5159|M.gilvum_PYR-GCK LVDLPMVRAYTDHVRLAQCPAHVSQLDTTIDQLDNEHEDITRSLNLAKAE TH_2611|M.thermoresistible__bu LVDMPTVRAYTDHVRLAQCPEQIAQLDSTIEQLDNEYQDITRQLNLAKAE MAB_1492|M.abscessus_ATCC_1997 VVDHHTVRDYVDQQRLALAGPEIDLLDTEITRLGGECDEIQSRQDILTGE MAV_1428|M.avium_104 --------AQLVAEAAAATKAAAAQAHSGRLQLLADIDTRAAAVTQTHAQ . . * : : : Mvan_1133|M.vanbaalenii_PYR-1 RDSLIEERAKAGGDRIGELERLAADAREQAKTRSQTKALFDAAVAEAG-L MSMEG_1281|M.smegmatis_MC2_155 RDSLIEERAKAGGDRIGELERLAHEARAQAESRRQARTLFDSAVGEAG-L MMAR_3068|M.marinum_M ADSLNAQISGSSAN-IAPLQSQVTAAETEAEQVERRRTTYEDMLAAQG-I MUL_2313|M.ulcerans_Agy99 ADSLNAQISGSSAN-IAPLQSQVTAAETQAEQVERRRTTYEDMLAAQG-I Mflv_5159|M.gilvum_PYR-GCK ADSLNAQISGSSAS-IGPLQSQVTAAETEAEQVSRRRNAYEDLLAAQG-L TH_2611|M.thermoresistible__bu ADSLTAQISGSSAS-LAPLQSQLTAAEAEAEQVSRRRTAYEDMLTAHG-L MAB_1492|M.abscessus_ATCC_1997 RDKLLGRIAAADSN-LAPLKSELAHARARAEEVSRRRTAYDSALWDLGHE MAV_1428|M.avium_104 VQQAAADHAVAQADAQACDTALQHATEALAELERRVQEAQRTVERSAG-- :. : : .. . :. *: : : * Mvan_1133|M.vanbaalenii_PYR-1 EPVADGDAFAALGAVVAGERPRLTGEKRDLDTATVDAIGREREHQRRCDV MSMEG_1281|M.smegmatis_MC2_155 TTVADEEAFLNLPTLVAAERTRLAAEKREVDAATVDAIGRERDCERKCTT MMAR_3068|M.marinum_M EIPDTADEFWNLREELLAQATELLAKVERNREASTDAEYAQKAARIARDD MUL_2313|M.ulcerans_Agy99 EIPDTADEFWNLREELLAQATELLAKVERNREASTDAEYAQKATRIARDD Mflv_5159|M.gilvum_PYR-GCK DAPETADAFWNLREELLAQATDLLAKVERNREASTDAEYAQKSARLVRDE TH_2611|M.thermoresistible__bu EIPETAEEFWNLRERLLTEATESLAKAERRREESTDAEYAQKAARLARDE MAB_1492|M.abscessus_ATCC_1997 DDIESAEEFEAMRVESLRAVTRINAELEAGHDAYVMAAGALSTARDQLRA MAV_1428|M.avium_104 ----------------REEADRLAARLDKID-----------AIQRDRER .. . Mvan_1133|M.vanbaalenii_PYR-1 IAEEVASLEQRTDNLPQEQVVVRAELCAALGLTPDDLPYAGELLDVHDEH MSMEG_1281|M.smegmatis_MC2_155 LSAEIESLEQRTSNLPHEQVVMREELCAAIGLTPEQLPYAGELLDVYDER MMAR_3068|M.marinum_M VAKELKRVEHVGSALPEFALAMRDHICAAIKVDATELPYIAELLDLRPGQ MUL_2313|M.ulcerans_Agy99 VAKELKRVEHVGSALPEFALAMRDHICAAIKVDAAELPYIAELLDLRPGQ Mflv_5159|M.gilvum_PYR-GCK AAKELKRVEHVGSALPEFALTMRDQICAAVGVDATDLPYVAELMDLKADQ TH_2611|M.thermoresistible__bu IAAELRRVEKVGSSLPEFALVMREQICAAIGVDPSELPYIAELMDLRPDQ MAB_1492|M.abscessus_ATCC_1997 ASAEFKRVEHLGTPVPPDEDRMRGEIAAALGLTAKDLPYVCELMDLRPGQ MAV_1428|M.avium_104 ISAELS------------TIAVTEELLRRIEDAAAAVDRIGDQLASTSAA : *. : .: : . : : : Mvan_1133|M.vanbaalenii_PYR-1 AQWRGAAERVLRGFALSLLVPQRHYDAVTAWVNGRRLTVGGRGAKLVYER MSMEG_1281|M.smegmatis_MC2_155 AEWRGAAERVLRGFALSLLVPQPHYDAVTRWVNERRLTVAGRGAKLVYER MMAR_3068|M.marinum_M TRWRLAVEKVLRGVGLRLLVPDQHWEKVLRFVNETDMRG-----RLQLHH MUL_2313|M.ulcerans_Agy99 TRWRLAVEKVLRGVGLRLLVPDQHWEKVLRFVNETDMRG-----RLQLHH Mflv_5159|M.gilvum_PYR-GCK TRWRTAVEKVLRGVGLRLMVPDQHWTEVLRFVNETNMRG-----RLQLHH TH_2611|M.thermoresistible__bu TRWRVAVEKVLRGAGLRLLVPDAYWGAVLRFVNETNMRG-----RLALHH MAB_1492|M.abscessus_ATCC_1997 ERWRKSVEKVLRSTGLCLLVPDQHHRQVLRYVNENPMRG-----YLQMER MAV_1428|M.avium_104 VEFTAVADIHLVIGDRQVSLPAGQSWSITAVG------------------ .: .: * : :* : Mvan_1133|M.vanbaalenii_PYR-1 VPQHRVRLQPTAHDGLLLADCIEVRD--GQFEEYLRAELMKRADFRCAAT MSMEG_1281|M.smegmatis_MC2_155 VAARRVRLQPAESDGLLLADCIEVRE--GPFEEYLRNELMKRADFRCATT MMAR_3068|M.marinum_M VRAKFLGAEPAEPEPNTLAGKLFPVDPKHLCAAEAVDIITGAGDHVCVDT MUL_2313|M.ulcerans_Agy99 VRAKFLGAEPAEPEPNTLAGKLFPVDPKHLCAAEAVDVITGAGDHVCVDT Mflv_5159|M.gilvum_PYR-GCK VRAKFLGATPVDPEPNTLAGKLFAVDPEHPCAAEAVDVVTAAGDHICVDT TH_2611|M.thermoresistible__bu VRARMYGAEPVEPEPNTLAGKLFVVDPNHPCAAEAADVIAAAGDHICVDD MAB_1492|M.abscessus_ATCC_1997 VIP---SGTPRRAEPGTLADCLRLTNPNHECASAAMNLVAGVGDYVLVDS MAV_1428|M.avium_104 --------PTAVEVPGVLTARVTPG----------ATTLDVQAKHAAAQQ . *: : : ... . Mvan_1133|M.vanbaalenii_PYR-1 LDEFRTERRAVTREGQVRSGDRHEKDDRHRVDDPRRWVLGWVNERKIAAM MSMEG_1281|M.smegmatis_MC2_155 LQEFRDLRRAVTREGQVRSGDRHEKDDRHRVDDPRRWVLGWVNERKLTAL MMAR_3068|M.marinum_M PDVFSRFRRAVTDTGLYKDSDRLAVKDDRRPVKLSEYLYQGDVTAKINAL MUL_2313|M.ulcerans_Agy99 PDVFSRFRRAVTDTGLYKDSDRLAVKDDRRPVKLSEYLYQGDVTAKINAL Mflv_5159|M.gilvum_PYR-GCK PEVFARFRRAVTDTGLYKDSDRLAIKDDRRPLKQSEYLYQGDVSAKINAL TH_2611|M.thermoresistible__bu PNVFGRFRRAVTDTGLYKESDRLAIKDDRRPVRQSEYLFQGDVSAKINAL MAB_1492|M.abscessus_ATCC_1997 PDEFSKHRRAVTDQGLRKDGDRRAVKDDRRELRASQYIYQGNAGDKRAAL MAV_1428|M.avium_104 ELAAALTAGAVADLGAARSADQRRRELQGTRDQLGATLAGLCGDEPLDEL **: * :..*: . : : Mvan_1133|M.vanbaalenii_PYR-1 RAELAELESQRDEAAAQAARLVKERDALQCRLDAFRSVEG-FRSWGELDA MSMEG_1281|M.smegmatis_MC2_155 RDEFADLERDRQEAAAVAAALSARREVLQHRLDALVRIEG-FRSWTELDA MMAR_3068|M.marinum_M TVELAAAEEAYQKARRTADDIAAQRQQWRDRAAACKAICEQYPQWSQIDT MUL_2313|M.ulcerans_Agy99 TVELTAAEEAYQKARRTADDIAAQRQQWRDRAAACKAICEQYPQWSQIDT Mflv_5159|M.gilvum_PYR-GCK TVDLAAAEEAYQKARRVADDIAAQRQQWRDRAAACKAICEQYPQWSQIDT TH_2611|M.thermoresistible__bu TVELAAAEEAYQKARRVADEIAAQRQQWRDWAASCRAICEQFPQWSQIDV MAB_1492|M.abscessus_ATCC_1997 SDDVVEAQQAVSDAEKFIGEMDTKREELRSEVVRWSKLHSQYEYWSQIDT MAV_1428|M.avium_104 RSRLARLRAEHPEQPAAPTGGAADLAAARTELEALAQARACASAECVTRR .. . . : Mvan_1133|M.vanbaalenii_PYR-1 DEAESRAKAHDAERVRLQAGSNRLAEITQALERNAENAVTVTDLIKKLTG MSMEG_1281|M.smegmatis_MC2_155 DEAVSRAGAHDAERARLQSGSSRLEEITRALERNAEEAGVVAERIRQLTG MMAR_3068|M.marinum_M ETADG-------HAERLREQYELLMADNPDIEALNARADECWSQIQKLMT MUL_2313|M.ulcerans_Agy99 ETADG-------HAERLREQYELLMADNPDIEALNARADECWSQIQKLMT Mflv_5159|M.gilvum_PYR-GCK ETADG-------HADRLREQYELLLAEHPDIEALNARADECWSQIQKLMT TH_2611|M.thermoresistible__bu ETADG-------HADRLREQYELLLAEHPDLDALNARAEDCWAQIQKLMT MAB_1492|M.abscessus_ATCC_1997 DSAEA-------AVARLQDQYDAMLEANPDLTGLQQQADSYLDEIKRLSE MAV_1428|M.avium_104 QAATA--------------AAARLAETATAATVLQNRLDTLRAELDAATG : * . : . : Mvan_1133|M.vanbaalenii_PYR-1 MLATAQSRMNQAKQERSRDDEFVAAHAP-----------DQREKARASYP MSMEG_1281|M.smegmatis_MC2_155 QLATTAAAVQRAQQDRKRDQEFVTAQSP-----------EQLEVARASYP MMAR_3068|M.marinum_M RRGAIQTRRDSLDERRTRLLELQERLSP----------AFVSEPLTELLQ MUL_2313|M.ulcerans_Agy99 RR-------DSLDERRTRLLELQERLSP----------AFVSEPLTELLQ Mflv_5159|M.gilvum_PYR-GCK RRGAVQTRRDALDDRRTRLLELAERLQP----------AFVSEPLTELLH TH_2611|M.thermoresistible__bu RRGAVQTRRDELDTRRTRLLELAERLSPPADERSRGEHRFVSEPLTELLQ MAB_1492|M.abscessus_ATCC_1997 RIGALRKQESEHDSRRTRLLDLLDNLSP----------REVGGHTRSGIE MAV_1428|M.avium_104 RLAAERASVGDEELAASADAALRAEQAA-------------ERRVAELAD . . : . Mvan_1133|M.vanbaalenii_PYR-1 ALTARLADSPPARAADCADSEAALSDDLHRRIERLSGQLNGHALNLTQHM MSMEG_1281|M.smegmatis_MC2_155 ALDRRLAASRPTRADDCAAAESALSEDLYRRIERLTRELGGYGQSLAQYM MMAR_3068|M.marinum_M RYAAQLPVA--LELLDPEPHRDALFAAIKKEREQLRESRRRSYDELARIL MUL_2313|M.ulcerans_Agy99 RYAAQLPVA--LELLDPEPHRDALFAAIKKEREQLRESRRRSYDELARIL Mflv_5159|M.gilvum_PYR-GCK RYAGQLPVS--LELLEPEPHRDALFNAIKKEREQLRESRRRSYDELARIL TH_2611|M.thermoresistible__bu RFAAQVPVG--LELLDPEPHREALFAAIKREREQLRESRRRSYDELARIL MAB_1492|M.abscessus_ATCC_1997 AYVPQLSSS--LDVLEPDAYRLELWRQIEKDQSVLRESVTRSRNELNRIL MAV_1428|M.avium_104 ALAAASPDSVAAELADATQESESLRERYEEAAGALREVT----------- . . : * . * Mvan_1133|M.vanbaalenii_PYR-1 TAVLNRWQELR-ADMDVNVESRADFLAFRERVATDDLPRFESEFKEQLNK MSMEG_1281|M.smegmatis_MC2_155 LEVLRRWPELR-ADMDATVEARGDFLAFRRRVATDDLPRFESEFKEQLNK MMAR_3068|M.marinum_M NTFDTSFPDAIPNDSDDFDERVHDYVALCRHIDERELPEAYERMMRLVTE MUL_2313|M.ulcerans_Agy99 NTFDTSFPDAIPNDSDDFDERVHDYVALCRLIDERELPEAYERMMRLVTE Mflv_5159|M.gilvum_PYR-GCK NTFDTSFPDAIPNDSENFDERVHDYVALCRHIDERELPEAYERMMRLVTE TH_2611|M.thermoresistible__bu NTFDTTFPDAIPNDSDVFDERVHDYVALCRHIDERELPEAYERMMRLVTE MAB_1492|M.abscessus_ATCC_1997 NAYDRDFPDSIPNDSENFDEKIHDYVALCRRIDERDLPAAYERMLRLITE MAV_1428|M.avium_104 -------------------------------------------------- Mvan_1133|M.vanbaalenii_PYR-1 NAIQELAGFNNWLGRQASAIDERVDRINDALGAVPYNPGRYIKLEKEPTS MSMEG_1281|M.smegmatis_MC2_155 NAIQELAGFNNWLSRQASAIDERIDRINEALGAVPYNPGRFIRLEKEPTT MMAR_3068|M.marinum_M QAPDAILTLHRVAEQEARRISGQIDRVNTGLAAVEFNRGTRLTLRATPRH MUL_2313|M.ulcerans_Agy99 QAPDAILTLHRVAEQEERRISGQIDRVNTGLAAVEFNRGTRLTLRATPRH Mflv_5159|M.gilvum_PYR-GCK QAPDAILTLHRVAEQEARRISDQIDRVNTGLGAVEFNRGTRLTLRATPRS TH_2611|M.thermoresistible__bu QAPDAILTLHRVAEQEARRIAEQIERVNTGLGAVEFNRGTRLTLRATPRQ MAB_1492|M.abscessus_ATCC_1997 QAPTAVLRLHQLAEEEAHRITDQIDRVNSGLGSVEFNRGTRLTLRAEPKA MAV_1428|M.avium_104 ------------IELSVFGSEGRQGKLDAAETEREHAASEHSQVGRRARA . : ::: . . . : . Mvan_1133|M.vanbaalenii_PYR-1 NQDVAQFRSDLRNLTNDTLTADGDQYSEQRFLDVKRIIERFRGRDGYAES MSMEG_1281|M.smegmatis_MC2_155 NQDVAQFRSDLRNLTNDALAVDGDQYSEQRFLDVKRIIERFRGREGYAES MMAR_3068|M.marinum_M LVAVDELTQIVRSISRRIAEVG--LGDKQAILDQYADILRLRNRLASTAP MUL_2313|M.ulcerans_Agy99 LVAVDELTQIVRSISRRIAEVG--LGDKQAILDQYAEILRLRNRLASTAP Mflv_5159|M.gilvum_PYR-GCK LTAVSELTEIVRAISRRIAEVG--LGDKQAILDQYADILRLRNRLASTSP TH_2611|M.thermoresistible__bu LTAVAELTEIVRAISRRIAEVG--LGDKQAILDQYADILRLRNRLASTTP MAB_1492|M.abscessus_ATCC_1997 LEAVGELNERARRISGRAVAVS--MGDEKAIHDQYQDILQLRNLLAAETP MAV_1428|M.avium_104 AQLLRSVMTRHRDTTR------------QRYVEPYRAELQRLGRPVFGPT : .. * : : : : . . Mvan_1133|M.vanbaalenii_PYR-1 -DKNWTRRVTDVRNWFVFSASERDVDTDLEWEHYSDSDGKSGGQKEKLAY MSMEG_1281|M.smegmatis_MC2_155 -DRNWTRRVTDVRNWFVFSASERDVDTGAEWEHYSDSDGKSGGQKEKLAY MMAR_3068|M.marinum_M EDKAWTRDALDVRNRFTFDCAEWDVDTEELIRTHSNAGDNSGGEQEKLMA MUL_2313|M.ulcerans_Agy99 EDKAWTRDALDVRNRFTFDCAEWDVDTEELIRTHSNAGDNSGGEQEKLMA Mflv_5159|M.gilvum_PYR-GCK EDKAWTRDALDVRNRFTFDCAEWDVATEELIRTHSNAGDNSGGEQEKLMA TH_2611|M.thermoresistible__bu EDRAWTRDALDVRNRFTFDCAEWDVATGELIRTHSNAGDNSGGEQEKLMA MAB_1492|M.abscessus_ATCC_1997 EARQWTRDALDVRNRFVLYCEERDARTGEPIRTYSNAGANSGGEQEKLMA MAV_1428|M.avium_104 FEVDID--------------SDLCIRSRTLNGITVPYESLSGGAKEQLGI : : *** :*:* Mvan_1133|M.vanbaalenii_PYR-1 TILAASLAYQFGLEWGVERSRDFRFAVIDEAFGRGSDVSTRYALDLFATL MSMEG_1281|M.smegmatis_MC2_155 TILAASLAYQFGLEWGAEESRDFRFAVIDEAFGRGSDVSTRYALDLFATL MMAR_3068|M.marinum_M FCLAGALSFNLASPESDNNKPVFAQLMLDEAFSKSDPQFAQQALHAFRKF MUL_2313|M.ulcerans_Agy99 FCLAGALSFNLASPESDNNKPVFAQLMLDEAFSKSDPQFAQQALHAFRKF Mflv_5159|M.gilvum_PYR-GCK FCLAGALSFNLAAPESSDNRPVFAQLMLDEAFSKSDPQFAQQALQAFRKF TH_2611|M.thermoresistible__bu FCLAGALSFNLASPDSRDNRPVFAQLMLDEAFSKSDPQFAQQALEAFRKF MAB_1492|M.abscessus_ATCC_1997 FCLAGALSFNLANPETGDNRPVFAQLMLDEAFSKSDPQFAQQALSAFRKF MAV_1428|M.avium_104 LARLAGAALVAKEDAVP--------VVVDDALGFTDPDRLAKMGQLFDSV .. : ::*:*:. . * .. Mvan_1133|M.vanbaalenii_PYR-1 GLQLLIVTPLQKVHVIEPYVKSIGIVDNP------TGTYSRLQTMTIEEY MSMEG_1281|M.smegmatis_MC2_155 GLQLLIVTPLQKVHVIEPYVKAIGIVDNP------TGTYSRLQTMTIEEY MMAR_3068|M.marinum_M GFQLVIVATVQNATTIEPYIDSVVMVSKTEPTGGNARPVASVATRTISEF MUL_2313|M.ulcerans_Agy99 GFQLVIVATVQNATTIEPYIDSVVMVSKTEPTGGNARPVASVATRTISEF Mflv_5159|M.gilvum_PYR-GCK GFQLVIVATVQNATTIQPYIDSVVMVSKTEATGRNARPVATVSTRTISEF TH_2611|M.thermoresistible__bu GFQLVIVATVQNATTIQPYVDSVVMVSKTEATGRNPRPVASVATRTISEF MAB_1492|M.abscessus_ATCC_1997 GFQLVIVATVQNTTTIQPYIDSVVMVSKPDGPG--VRPVASTRTVPIGEL MAV_1428|M.avium_104 GSHGQVIVLTCSPDRYDGVKGAHRIDLSA--------------------- * : ::. . : : : .. Mvan_1133|M.vanbaalenii_PYR-1 RDRRDRPLR--------- MSMEG_1281|M.smegmatis_MC2_155 RARRNGTRP--------- MMAR_3068|M.marinum_M TSLRQEMRKTAERVPAGV MUL_2313|M.ulcerans_Agy99 TSLRQEMRKTAERVPAGV Mflv_5159|M.gilvum_PYR-GCK TDLRHAMRAEAK-VPAGV TH_2611|M.thermoresistible__bu TALREKMG--SSRVPAGV MAB_1492|M.abscessus_ATCC_1997 GDVRKAVSAR-------- MAV_1428|M.avium_104 ------------------