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MTSAPARERLLTPSKVTAWLDCPHYLALSARVEDGTMPRPELRFGSFAELLLNKGLAHEQDCLAEYRRQE RRILEVPAKAKGQTFASWVAETGNPLDGVHDVVYQMPFIHNGIRGVADFVVRVQDPDTGAVSYEPVDAKL TRVDAKPGHVLQLCFYADAIEALTGRRPEHMHIWLGSGRMETLRVSDFQPYWRRLQGQLAAALAGGPAEG TVAEQCAHCEFCEFQPICEAQWRDADSLIYVAGIRKPDIATLVEADIATLTALATSDGPVDILAPDRFTR LRGQAALQLAAREQSDARPPFELIEPGDEPWGHGFETLPEPDAGDVFLDFEGHPFWRADTGLFFLFGLIE QSEDRWRYRSWWAHDPDREAVAVDELVDYLARRREQFPGMHVYHYNHTERSALQRMTETHGVAEVELAQL IDTGAFVDLLLVARNSIQVGTESYGLKHLERLTDFERSHEIDQGAGAVVQYEHYMAEPNQDDLDAIAAYN EDDVRATLALRDWLVGHRPPGLPWRPAVTEPNPEQPELDELVVRLHEFPSGTDEHNLGDLLRYWLDEWRA YIAPKKVKLAADPLDLLDDAEVIADLGGVALIERLGVRGTPITPAMRFTFPAQNIDRFPSSGGKVMIAAL PEERRSVEIVHLDRDALTIDVVWNKDLQDADWQPRVAVLDDWVNTQPKPAALQAFAEDLLEARGANPVTL ALLRRDLPRFTDQPRTAFADDLDEMAGWVTRLDHSVVAVQGPPGTGKTYRAARLIRALVCAGQRVGVTAL SHHAIANVLEGVVKAFTETGELELLHAVCNAGTSSVQRVPGVTYGDNGKCARDEFNVVAGTTWLFSNALM RNAPVDVLLIDEAGQLALADALAASGAAHNLVLLGDPLQLPQVAQAKHPGISGRSVLDHVVGDDVLLPPD RGVFLHETRRMHPDVCEFISTQIYDGRLHSFPDCGRQSTVAGTGLRWLRVDHAGNRTFSVQEADAIAQEL SRLIDTPWTNHKGETERLQAGDFMVVAPYNLQVNTTHARLAQDAALRDVPVGTVDKFQGREAAVVFFSMA ASSGEDITRGVEFLFSRNRLNVAVSRARCLAYLVCTDALLDTRARTVEEMRLISTLNAFVDTAALHESRE V
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1107 | - | - | 100% (1121) | hypothetical protein Mvan_1107 |
| M. vanbaalenii PYR-1 | Mvan_4472 | - | e-127 | 34.36% (1106) | RecB family-like nuclease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1283c | - | 1e-70 | 44.44% (378) | hypothetical protein Mb1283c |
| M. gilvum PYR-GCK | Mflv_2223 | - | 1e-128 | 33.21% (1063) | RecB family-like nuclease |
| M. tuberculosis H37Rv | Rv1251c | - | 1e-70 | 44.44% (378) | hypothetical protein Rv1251c |
| M. leprae Br4923 | MLBr_01098 | - | 2e-70 | 41.75% (424) | hypothetical protein MLBr_01098 |
| M. abscessus ATCC 19977 | MAB_1401c | - | 1e-126 | 34.40% (1064) | hypothetical protein MAB_1401c |
| M. marinum M | MMAR_4191 | - | 1e-121 | 34.21% (1061) | hypothetical protein MMAR_4191 |
| M. avium 104 | MAV_1388 | - | 1e-127 | 35.27% (1066) | ATPase |
| M. smegmatis MC2 155 | MSMEG_5044 | - | 9e-64 | 41.53% (378) | ATPase |
| M. thermoresistible (build 8) | TH_3422 | - | 0.0 | 76.08% (1108) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4495 | - | 1e-120 | 34.02% (1061) | hypothetical protein MUL_4495 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01098|M.leprae_Br4923 -----MFVT-----DETIVYSASDLAAASRCEYALLRDFDARLGRGPVVA
MAV_1388|M.avium_104 -----MFVT-----GDSIVYSASDLAAAARCEFALLRDFDAKLGRGPAVT
Mb1283c|M.bovis_AF2122/97 -----MFVT-----GDSIVYSASDLAAAARCQYALLREFDAKLGRGPAVA
Rv1251c|M.tuberculosis_H37Rv -----MFVT-----GDSIVYSASDLAAAARCQYALLREFDAKLGRGPAVA
MMAR_4191|M.marinum_M --MAAVFVA-----DDVVVYSASDLAAAARCEFAFLRHFDSKLGRGPAIS
MUL_4495|M.ulcerans_Agy99 -----MFVA-----GDVVVYSASDLAAAARCEFAFLRHFDSKLGRGPAIS
Mflv_2223|M.gilvum_PYR-GCK -----MFVATDAG-VDRVIFSASDLAAAARCEYALLRSFDDRLGRGPAVS
MSMEG_5044|M.smegmatis_MC2_155 -----MFVTEDGGSGPRVIYSASDLAAAARCEYALLRAFDAQLGRGPAVS
MAB_1401c|M.abscessus_ATCC_199 -----MFVL-----DDRVVYSASDLASAARCEYALLRVFDAKLGWAPAPP
Mvan_1107|M.vanbaalenii_PYR-1 MTSAP---------ARERLLTPSKVTAWLDCPHYLALSARVEDGTMPRPE
TH_3422|M.thermoresistible__bu -VTTT---------VTERLLTPSKVTAWLDCPHYLSLCAQVDDGILPRPE
: :.*.::: * . : * *
MLBr_01098|M.leprae_Br4923 TTEDELFARTSALGADHEQRHLDQLRHEFGDAVAVIGRP-AYTYAGFAAA
MAV_1388|M.avium_104 -VEDDLLIRTATLGAEHERRELARLRERFGDAVAVIGRP-AYTPAALTAA
Mb1283c|M.bovis_AF2122/97 -VDDELMARAAVLGSAHEGRRLDQLRHEFGDAVAIIGRP-AYTPAGLAAA
Rv1251c|M.tuberculosis_H37Rv -VDDELMARAAVLGSAHEGRRLDQLRHEFGDAVAIIGRP-AYTPAGLAAA
MMAR_4191|M.marinum_M -AEDDLLARTTELGNEHERRTLDRLRDQFG-EIAVIGHP-AYTLAGLTAA
MUL_4495|M.ulcerans_Agy99 -AEDDLLVRTTELGNEHERRTLDRLRDQFG-EIAVIGHP-AYTLVGLTAA
Mflv_2223|M.gilvum_PYR-GCK -GDDELLARTATLGDQHEKRHLDELA--LASDVTVIGRP-AYTVAGLTDA
MSMEG_5044|M.smegmatis_MC2_155 -SEDELLKRTAQLGGEHEQRHLDELR--EGSEITVIGRP-RYTVPGLTAA
MAB_1401c|M.abscessus_ATCC_199 -RDDELLARTAILGDAHEAHHLSALQARFGAGVAGIPFPPAFTLEGLQAA
Mvan_1107|M.vanbaalenii_PYR-1 LRFGSFAELLLNKGLAHEQDCLAEYRRQERRILEVPAKA---KGQTFASW
TH_3422|M.thermoresistible__bu SRFGSFAELLLDKGRAHEQACLADFERQGKRVLRIPDRE---NGESFAAW
..: * ** * : . :
MLBr_01098|M.leprae_Br4923 AEATQRAIANRAPAVYQAAMFDGRFVGFIDFLVRDGE------QYRVVDT
MAV_1388|M.avium_104 SEATRRAVADRAPVIYQAAMFDGRFLGFADFLVRDGE------RYQVVDT
Mb1283c|M.bovis_AF2122/97 ADATRRAIANHAPVVYQAAMFDGRFVGFADFLIRDGH------RYRVADT
Rv1251c|M.tuberculosis_H37Rv ADATRRAIANHAPVVYQAAMFDGRFVGFADFLIRDGH------RYRVADT
MMAR_4191|M.marinum_M AEATQRAIADRAPVVYQAAMFDGRFVGFADFLIRDRE------RYRITDT
MUL_4495|M.ulcerans_Agy99 AEATQRAIADRAPVVYQAAMFDGRFVGFADFLIRDRE------RYRITDT
Mflv_2223|M.gilvum_PYR-GCK AGQTLRAVERRAPVIYQAAMFDGRFAGFADFLLLEEGPDG--QRYRLRDT
MSMEG_5044|M.smegmatis_MC2_155 ANATLAAVTQRAPVIYQAAMFDGRFAGFADFLILSDG------QYRLRDT
MAB_1401c|M.abscessus_ATCC_199 AAATRRAFEQGYPAVYQAAMFDGRFLGFADFVVREGE------HYLVCDT
Mvan_1107|M.vanbaalenii_PYR-1 VAETGNPLDGVHDVVYQMPFIHNGIRGVADFVVRVQDPDTGAVSYEPVDA
TH_3422|M.thermoresistible__bu VARVGNPLTDDHDVIYQMPFVHNGIAGIADFLVRVTHPDTGEVSWEPVDA
. .. .:** .:... : *. **:: : *:
MLBr_01098|M.leprae_Br4923 KLARS-PKVTALLQLAAYADALAHSGVPVAPEAELRLGDGMVVSYRICDL
MAV_1388|M.avium_104 KLARS-EKVTALLQLAAYADALAAAGVPVAPEAELRLGDGTAVRHRVCDL
Mb1283c|M.bovis_AF2122/97 KLARS-PTVTALLQLAAYADALVHSGVPVAADAELELGDGTIVRYRVGEL
Rv1251c|M.tuberculosis_H37Rv KLARS-PTVTALLQLAAYADALVHSGVPVAADAELELGDGTIVRYRVGEL
MMAR_4191|M.marinum_M KLARS-PKVTALMQLGAYADALTGAGVPVAPEADLELGDGTVVHFRVSDL
MUL_4495|M.ulcerans_Agy99 KLARS-PKVTALMQLGAYADALTGAGVPVAPEADLELGDGTAVHFRVSDL
Mflv_2223|M.gilvum_PYR-GCK KLARS-VKVEALLQMAAYVETLTAAGVPVAPEIDLVLGDGTAVSYPVDEL
MSMEG_5044|M.smegmatis_MC2_155 KLARS-VKVEALLQLAAYSETLSAAGVPVAPEVELVLGDGAVATYPVDEL
MAB_1401c|M.abscessus_ATCC_199 KLARS-AKVTALLQLAAYADSLAATGVPVAPSVRLILGDRSAVDYPAADL
Mvan_1107|M.vanbaalenii_PYR-1 KLTRVDAKPGHVLQLCFYADAIEALTGRRPEHMHIWLGSGRMETLRVSDF
TH_3422|M.thermoresistible__bu KLTRIEAKPGHVLQLCFYADALEALTGRRPEHMHIWLGSGQLETLRVNEF
**:* . ::*: * ::: . : **. ::
MLBr_01098|M.leprae_Br4923 IPVYRSQRSLLQRLLDRHYTAGTAVRWQDDEVRSCFRCPQCTEQLRATDD
MAV_1388|M.avium_104 VPVYRSARARLQRLLDEHRAGGAAVRWDDENVTACFRCAVCVEQLRATDD
Mb1283c|M.bovis_AF2122/97 IPVYRSQRALLQRLLDGHYTAGTAVRWDDERVQACFRCPQCTERLRASDD
Rv1251c|M.tuberculosis_H37Rv IPVYRSQRALLQRLLDGHYTAGTAVRWDDERVQACFRCPQCTERLRASDD
MMAR_4191|M.marinum_M IPVYRAQRAELQRLLDEHYAADTAVCWDDHGVRACFRCELCMEELRRRDD
MUL_4495|M.ulcerans_Agy99 IPVYRAQRAELQRLLDEHYAADTAVCWDDHGVRACFRCELCMEELRRRDD
Mflv_2223|M.gilvum_PYR-GCK LPVYRPRRAALQQLLEDHLAGGRAVEWEDEHVRACFRCAECDTQVRARDD
MSMEG_5044|M.smegmatis_MC2_155 LPVYRPRRAALEHLLDAHLASGEPVSWEDTEIRACFRCPECEVQVRAHDD
MAB_1401c|M.abscessus_ATCC_199 VGVYRQRRKQLQDLLDHHLSGGVPVRWSDHHVRACFRCPVCEPEVERTDD
Mvan_1107|M.vanbaalenii_PYR-1 QPYWRRLQGQLAAALAGGPAEG-TVAEQCAHCEFCEFQPICEAQWRDADS
TH_3422|M.thermoresistible__bu QPYWRRLQTQLAAALAAGPEAG-TVAEQCAHCEFCEFQPTCEMYWRDTDS
:* : * * . .* . * * . *.
MLBr_01098|M.leprae_Br4923 LLLIAGMRISQRSKLLNVGITTIAELADHSG--PVPDLSSSALSELTAQA
MAV_1388|M.avium_104 VLLVAGMRVSQRDKLFDAGISTVAELAAHRG--PVPELAAGVVAKLTAQA
Mb1283c|M.bovis_AF2122/97 LLLVGGMRVRQRDKLLEAGITTIAELADHTA--PVPGLTTNALGKLTAQA
Rv1251c|M.tuberculosis_H37Rv LLLVGGMRVRQRDKLLEAGITTIAELADHTA--PVPGLTTNALGKLTAQA
MMAR_4191|M.marinum_M LLLVAGMRVSQREKLLDAGITTIGGLASHTG--AVPELSANALAKLAAQA
MUL_4495|M.ulcerans_Agy99 LLLVAGMRVSQREKLLDAGITTIGGLASHTG--AVPELSANALAKLSAQA
Mflv_2223|M.gilvum_PYR-GCK LLLVAGMRVSARARLLDAGITTVHELAAHRG--PVAELSSRTVTALTAQA
MSMEG_5044|M.smegmatis_MC2_155 LLLVAGMRTSQRARLIDAGITTVADLAARRDDEPVEGLHPRIAQGLTAQA
MAB_1401c|M.abscessus_ATCC_199 LLLVAGMRVSQRAALLQAGVGTVAQLATRTE--PVADLSARSLRQLMAQA
Mvan_1107|M.vanbaalenii_PYR-1 LIYVAGIRKPDIATLVEADIATLTALATSDG--PVDILAPDRFTRLRGQA
TH_3422|M.thermoresistible__bu LIYVANIRKPDREALAGADIATLTALATSDG--PVEGMDPDRLARLRRQA
:: :..:* * ..: *: ** .* : . * **
MLBr_01098|M.leprae_Br4923 KLQVQQRNTG----TPQFEIVDPQP------LALLPDPDPGDLFFDFEGD
MAV_1388|M.avium_104 KLQVRERETG----VPQVEIVDPQP------LALLPEPDPGDLFFDFEGD
Mb1283c|M.bovis_AF2122/97 KLQIRQRDTG----APQFEIVDPRP------LTLLPEPNPGDLFFDFEGD
Rv1251c|M.tuberculosis_H37Rv KLQIRQRDTG----APQFEIVDPRP------LTLLPEPNPGDLFFDFEGD
MMAR_4191|M.marinum_M KVQVQQRDTS----TPQYEISDPQP------LALLPEPNPGDLFFDFEGD
MUL_4495|M.ulcerans_Agy99 KVQVQQRDTG----APQYEISDPQP------LALLPEPNPGDLFFDFEGD
Mflv_2223|M.gilvum_PYR-GCK RLQVARRVVENGTEKPPYEIVDPQP------LMVLPDADKGDLFFDFEGD
MSMEG_5044|M.smegmatis_MC2_155 RLQRAPRTGK----KPPYEVVDPQP------LMSLPNPDRGDLFFDFEGD
MAB_1401c|M.abscessus_ATCC_199 ELQIRQRDSG----TPQFEVADPIP------LGTLPAPNPGDVFFDFEGD
Mvan_1107|M.vanbaalenii_PYR-1 ALQLAAREQSD--ARPPFELIEPGDEPWGHGFETLPEPDAGDVFLDFEGH
TH_3422|M.thermoresistible__bu ALQLAAREQQR--EKPPFELIRPGPEPWGHGFEMLPEPDGGDVFLDFEGH
:* * * *: * : ** .: **:*:****.
MLBr_01098|M.leprae_Br4923 PLWTVDGQEWGLEYLFGVLDSEIS---GTFRPLWAHNRVEERKALTEFLK
MAV_1388|M.avium_104 PLWTADGREWGLEYLFGVLEAGPS---GRFRPLWAHNRSEERKALTDFLA
Mb1283c|M.bovis_AF2122/97 PLWTADGKQWGLEYLFGVLEAGRA---GVFRPLWAHDRTAERQALTDFLA
Rv1251c|M.tuberculosis_H37Rv PLWTADGKQWGLEYLFGVLEAGRA---GVFRPLWAHDRTAERQALTDFLA
MMAR_4191|M.marinum_M PLWTADGHEWGLEYLFGVLEAGKK---GAFRPLWAHDRRDERKALTDFLA
MUL_4495|M.ulcerans_Agy99 PLWTADGHEWGLEYLFGVLEAGKK---GAFRPLWAHDRRDERKALTDFLA
Mflv_2223|M.gilvum_PYR-GCK PLWTTDGRDWGLEYLWGVLTPG-----DEFQPFWAHNRTEERQALQDFLK
MSMEG_5044|M.smegmatis_MC2_155 PLWTDDGVQWGLEYMFGVLGTAPRA-DEDFHPLWAHNRREERQALRDFLA
MAB_1401c|M.abscessus_ATCC_199 PLWTEDGVHWGLEYLFGVLEYDRSG-NEKFRPIWAHDRRTERKALLAFLE
Mvan_1107|M.vanbaalenii_PYR-1 PFWRADT---GLFFLFGLIEQSED--RWRYRSWWAHDPDREAVAVDELVD
TH_3422|M.thermoresistible__bu PFWRADT---GLFFLFGLIEQDDDGGRWRYRCWWAHDRDEEAAAVAQLVE
*:* * ** :::*:: :: ***: * *: ::
MLBr_01098|M.leprae_Br4923 MVTKRRKQRPHMHVYHYAPYEKTALLRLAGRYGVCEDEVDELLRSGTLVD
MAV_1388|M.avium_104 LVANRRRRRPNMHIYHYAPYEKTALLRLAGRYGVGEDQVDELLRSGTLVD
Mb1283c|M.bovis_AF2122/97 IVARRRRRHPNMHIYHYAPYEKTALLRLVGRYGIGEDDVDDLLRNGVLVD
Rv1251c|M.tuberculosis_H37Rv IVARRRRRHPNMHIYHYAPYEKTALLRLVGRYGIGEDDVDDLLRNGVLVD
MMAR_4191|M.marinum_M LVAKRRKRHPNMHIYHYAPYEKTALLRLAGRYGVGEDAIDDLLRNGVLVD
MUL_4495|M.ulcerans_Agy99 LVAKRRKRHPNMHIYHYAPYEKKALLRLAGRYGVGEDAIDDLLRNGVLVD
Mflv_2223|M.gilvum_PYR-GCK FVRKRRNRYPGMHIYHYAAYEKSALLRLAGRYGVGEHEVDELLRDGVLVD
MSMEG_5044|M.smegmatis_MC2_155 LVRKRRKRHPHMHVYHYAAYEKTALLRLAGRYGEGEDEVDELLRAGVLVD
MAB_1401c|M.abscessus_ATCC_199 LVAKRRRRYPGMHVYHYAAYEKSALLRLAGRYGIGEQQIDDLLRDNILVD
Mvan_1107|M.vanbaalenii_PYR-1 YLARRREQFPGMHVYHYNHTERSALQRMTETHGVAEVELAQLIDTGAFVD
TH_3422|M.thermoresistible__bu YLVERRKQHPAMHVYHYNHTERSALQRMAEEHGVAELALAELIDTGAFVD
: .**.: * **:*** *:.** *:. :* * : :*: . :**
MLBr_01098|M.leprae_Br4923 LYPLVSKSIRVGAESFSLKALEPLYMGKQLRSGDVTTATDSITCYGRYCE
MAV_1388|M.avium_104 LYPLVRRSIRVGADSFSLKALEPLYMGSRLRAGEVTTAAGSITSYARYCE
Mb1283c|M.bovis_AF2122/97 LYPLVRKSIRVGTDSFSLKALEPLYLGTQPRSGDVTTAADSINSYARYCE
Rv1251c|M.tuberculosis_H37Rv LYPLVRKSIRVGTDSFSLKALEPLYLGTQPRSGDVTTAADSINSYARYCE
MMAR_4191|M.marinum_M LYPVVRKSFRVGAESVSLKALEPLYMGAQLRSGEVTTATDSITSYARYSQ
MUL_4495|M.ulcerans_Agy99 LYPVVRKSFRVGAESVSLKALEPLYMGAQLRSGEVTTATDSITSYARYSQ
Mflv_2223|M.gilvum_PYR-GCK LYPLVRKSIRVGTENYSIKSLEPLYMGNELRDGDVTTATASITEYAHYCE
MSMEG_5044|M.smegmatis_MC2_155 LYPLVRKSIRVGTENYSLKSLEPLYMGAQLRDGDVTTATDSITQYGLYCT
MAB_1401c|M.abscessus_ATCC_199 LYPVVRKSIRCGSNGYGLKALEPLFIESGKRSGEVTTAVDSINEYARYCA
Mvan_1107|M.vanbaalenii_PYR-1 LLLVARNSIQVGTESYGLKHLERLTDFER--SHEIDQGAGAVVQYEHYMA
TH_3422|M.thermoresistible__bu LLLVARNSIQVGAESYGLKHLERLTDFER--SHDIDQGAGAVVQYEQYIA
* :. .*:: *::. .:* ** * :: .. :: * *
MLBr_01098|M.leprae_Br4923 LLSAGNFDEAATVLKEIEDYNHYDCRSTRELRNWLLLQAYEAGVVPVGAQ
MAV_1388|M.avium_104 LQADGRADEAVAVLKEIEDYNHYDCRSTQELRNWLMLRAYESGVLPVGAQ
Mb1283c|M.bovis_AF2122/97 LRAAGRIDEAATVLKEIEGYNHYDCRSTRALRDWLLMRAWEAGVTPIGAQ
Rv1251c|M.tuberculosis_H37Rv LRAAGRIDEAATVLKEIEGYNHYDCRSTRALRDWLLMRAWEAGVTPIGAQ
MMAR_4191|M.marinum_M LRADGRLDEAATVLKEIEDYNHYDCRSTRELRDWLLIRAWEAGVTPIGVQ
MUL_4495|M.ulcerans_Agy99 LRADGRLDEAATVLKEIEDYNHYDCRSTRELRDWLLIRAWEAGVTPIGVQ
Mflv_2223|M.gilvum_PYR-GCK LRDDGNAEEAASVLKAIEDYNHYDCRSTRRLRDWLMNRAIECGVPPRGPV
MSMEG_5044|M.smegmatis_MC2_155 LRAEGRDDEAALVLKEIEDYNLYDCVSTRKLRDWLINRAIECSVPPLGAQ
MAB_1401c|M.abscessus_ATCC_199 LRDNGDPG-AQEVLDSIAEYNRYDCASTRKLRDWLLVRAFEHGITHLSSS
Mvan_1107|M.vanbaalenii_PYR-1 EPNQ-------DDLDAIAAYNEDDVRATLALRDWLVGHRPPG--LPWRPA
TH_3422|M.thermoresistible__bu DGNQ-------AHLDAIAAYNADDVRATLALRDWLVEHRPPG--LPWRSA
*. * ** * :* **:**: :
MLBr_01098|M.leprae_Br4923 PVPEGNTVK--DDDELSAILSALSGFTGDVAVGDRTPEQTAIALVAAARG
MAV_1388|M.avium_104 PVGDGNTVD--DRDELVATLSAFTGAAG---IDERTPQQTAVALLAAARG
Mb1283c|M.bovis_AF2122/97 PVPDADPID--DGDSLASVLSKFTGDAAA---GERTPEQTAVALLAAARG
Rv1251c|M.tuberculosis_H37Rv PVPDADPID--DGDSLASVLSKFTGDAAA---GERTPEQTAVALLAAARG
MMAR_4191|M.marinum_M PVPRRDAIE--DHDELAATLSDFAGDAAA---GNRTAEQTAVALLAAARG
MUL_4495|M.ulcerans_Agy99 PVPRRDAIE--DHDELAATLSDFAGDAAS---GNRTAEQTAVALLAAARG
Mflv_2223|M.gilvum_PYR-GCK RPSPDTDRPRAEVDAVERTLLKFAGDGI----EARTPEQRAAAMMAAAKG
MSMEG_5044|M.smegmatis_MC2_155 PVGRDTAP--EPEDQIARTLRRFVGD------DERTPQQQAVAMIAAARG
MAB_1401c|M.abscessus_ATCC_199 SSAAGEQPE-QESDEVGRALADFAGDGAP---ADRAPDQTAAAMIAAARG
Mvan_1107|M.vanbaalenii_PYR-1 VTEPNPEQP--ELDELVVRLHEFPSGTDE---------------------
TH_3422|M.thermoresistible__bu VLEPDPELP--GLGETVERLHQFPVGSDE---------------------
. * :
MLBr_01098|M.leprae_Br4923 YHRREDKPFWWGHFDRLNFPVGEWADNTDVFVADDASIIIDWHTPPRARK
MAV_1388|M.avium_104 YHRREDKPFWWAHFDRLNFPIDEWADNTDVFVAEQASVCVDWQTPARARK
Mb1283c|M.bovis_AF2122/97 YHRREDKPFWWAHFDRLNYPVDEWSDSTDVFLASEASVTVDWHMPPRARK
Rv1251c|M.tuberculosis_H37Rv YHRREDKPFWWAHFDRLNYPVDEWSDSTDVFLASEASVTVDWHMPPRARK
MMAR_4191|M.marinum_M YHRREDKPFWWSHFDRLNYPIDEWSDSTDVFIVDHASVTVTWHTPARARK
MUL_4495|M.ulcerans_Agy99 YHRREDKPFWWSHFDRLNYPIDEWSDSTDVFIVDHASVTVTWHTPARARK
Mflv_2223|M.gilvum_PYR-GCK FHKREDKPFWWGHFDRVNNPVEEWADDSDVFIADRHEIVEDWHTPPRARK
MSMEG_5044|M.smegmatis_MC2_155 YHRREDKPFWWSHFDRLNHPVEEWSDGAGVFVADTAHVEVDWHTPPRARK
MAB_1401c|M.abscessus_ATCC_199 YHNRERKPFWWSHFDRLNNPVDEWADTAGVFIVESARLVEDWHKSGSQRK
Mvan_1107|M.vanbaalenii_PYR-1 HNLGDLLRYWLDEWRAYIAPKKVKLAADPLDLLDDAEVIADLGGVALIER
TH_3422|M.thermoresistible__bu HNLGDLLNYWRDEGLAYIAPKNAKLATDPVDLYDDAEVIADLRPETLLES
.: : :* . * : : . : .
MLBr_01098|M.leprae_Br4923 PQRRVRLRGRLARGNLGSAVFALYDPPAPLAMDV-HPGRRAAGRAEVVEA
MAV_1388|M.avium_104 PQRRVRLRGELARGELRTEVFALYDPPAPPGMTD-NPDRRGAGRATVVEA
Mb1283c|M.bovis_AF2122/97 PQRRVRLTGELARGDLNGNVFALYEPPAPPGMTD-NPDRRAAGPAAVVET
Rv1251c|M.tuberculosis_H37Rv PQRRVRLTGELARGDLNGNVFALYEPPAPPGMTD-NPDRRAAGPAAVVET
MMAR_4191|M.marinum_M PQRRVRLTGELARGDLKTSVFALYQPPAPPSMTA-DPDLRAAGHAEIVEL
MUL_4495|M.ulcerans_Agy99 PQRRVRLTGQLARGDLKTSVFALYQPPAPPSMTA-DPDLRAAGHAEIVEL
Mflv_2223|M.gilvum_PYR-GCK PQRHVRLFGEIANGGLATDMYALYDPPTPEGLSD-DPDRRGFASVSVADC
MSMEG_5044|M.smegmatis_MC2_155 PQRWVRLTGAMAAGELSREMYALYEPPAPSGLTD-DPERRAFGSVQVLEA
MAB_1401c|M.abscessus_ATCC_199 LRRHVQVTGDLAGGVLEDSVYALYEPPAPPGLGDGDPDRRASGSATVVEI
Mvan_1107|M.vanbaalenii_PYR-1 LGVRGTPITPAMRFTFPAQNIDRFPSSGGKVMIAALPEERRSVEIVHLDR
TH_3422|M.thermoresistible__bu T---GRARHPRRRFRFPDQDVDRFPSDGGSVMVATSTGERLCTGIANLDR
: : . : . * :
MLBr_01098|M.leprae_Br4923 DDLS-IPTEVVIVERVGNDGNTFHQLPFALTPGPPIATTALRDSIESTAT
MAV_1388|M.avium_104 DDPA-LPTEVVVLERVTSDGKPFHQLPFALTPGPPIPTTALRDSIEATVA
Mb1283c|M.bovis_AF2122/97 DDPT-VPTEVVIVERTGSDGNTFQQLPFALAPGPPVPTTALRESIESTAA
Rv1251c|M.tuberculosis_H37Rv DDPT-VPTEVVIVERTGSDGNTFQQLPFALAPGPPVPTTALRESIESTAA
MMAR_4191|M.marinum_M DDPS-LPTDVVILERTGADGATFQQLPFALTPGPPVPTRALRDSIEATAA
MUL_4495|M.ulcerans_Agy99 DDPS-LPTDVVILERTGADGATFQQLPFALTPGPPVPTRALRDSIEATAA
Mflv_2223|M.gilvum_PYR-GCK DNPE-APTEVVIVERRPTGGDVYTQVPFALTPGAPISTALLQNAVADTAA
MSMEG_5044|M.smegmatis_MC2_155 DDAS-APTEVLICEREPKEGGTFHQLPFALTPGPPIRTTALQNSIEATAA
MAB_1401c|M.abscessus_ATCC_199 TESGGVPVEVTIRELTPKNGEVFSAMPMALTPGPPVMTKALEAAIEEVAM
Mvan_1107|M.vanbaalenii_PYR-1 DALT---IDVVWNKDLQDADWQPRVAVLDDWVNTQPKPAALQAFAEDLLE
TH_3422|M.thermoresistible__bu DAHT---LDLVWNDKLQEAGCPPRIAVLHDWVKSEVKVKALQAFAEDLLD
:: . . : . *.
MLBr_01098|M.leprae_Br4923 TLAASLPQLPRTALIDILLRRIPRTHSGATLPR-GTDTVADITAAVLDLD
MAV_1388|M.avium_104 AVAAGLPRLPDSAVVDVLLRRAPRTRSGAALPR-SADTVADIASALTDLD
Mb1283c|M.bovis_AF2122/97 AVASGSPQLPSTALMDVLLRRPPRTRSGAALPR-SSDPVTDIAAAALDLD
Rv1251c|M.tuberculosis_H37Rv AVASGSPQLPSTALMDVLLRRPPRTRSGAALPR-SSDPVTDIAAAALDLD
MMAR_4191|M.marinum_M AAAAELPRLPRTALIDVLLRCPPRTRSAAPLPR-SGNTVADITAAVLDLD
MUL_4495|M.ulcerans_Agy99 AAAAELPRLPRTALIDVLLRCPPRTRSAAPLPR-SGDTVADITAAVLDLD
Mflv_2223|M.gilvum_PYR-GCK LIAAGLPNLPADALTDIFLRRPPRTRSGNPLPR-TGGTVADLTAALLDLD
MSMEG_5044|M.smegmatis_MC2_155 QIAEGLPRLPGNAVVDILLRRPPRTRSGGPLPHGQAAKHELITAALLDLD
MAB_1401c|M.abscessus_ATCC_199 GVAHRLPEMPRTASLDILLRRNP--RGGPLPPVDAGGYAGAITSALRALD
Mvan_1107|M.vanbaalenii_PYR-1 ARG------ANPVTLALLRRDLPRFTDQPRTAF--ADDLDEMAGWVTRLD
TH_3422|M.thermoresistible__bu GRN------PNPVTLALLRRELPRFTDRPRTAF--VDDLDDMIDWGTRLD
. . :: * * . . : **
MLBr_01098|M.leprae_Br4923 SSYLAVHGPPGTGKTHTAAHVITQLVSNHSWRIGVVAQSHAAVENLLDGV
MAV_1388|M.avium_104 SSYLAVHGPPGTGKTHTAARVIVRLVAEHRWRVGVVAQSHATVENLLDCV
Mb1283c|M.bovis_AF2122/97 SSYLAVHGPPGTGKTYTAARVIAELVTEHAWRIGVVAQSHATVENLLEGV
Rv1251c|M.tuberculosis_H37Rv SSYLAVHGPPGTGKTYTAARVIAELVTEHAWRIGVVAQSHATVENLLEGV
MMAR_4191|M.marinum_M SSYLAVHGPPGTGKTHTAARVIGRLVQEHCWRVGVVAQSHATVENLLDCV
MUL_4495|M.ulcerans_Agy99 SSYLAVHGPPGTGKTHTAARVIGRLVQEHCWRVGVVAQSHATVENLLDCV
Mflv_2223|M.gilvum_PYR-GCK SSYLAVHGPPGTGKTYTSGKVIAALLTEHQWKIGVVAQSHAVVENLFGDI
MSMEG_5044|M.smegmatis_MC2_155 SSYLAVHGPPGTGKTFTSAAVIARLVNRHHWRIGVVAQAHAVVENLFRDV
MAB_1401c|M.abscessus_ATCC_199 SSYLAVHGPPGTGKTFTAARVIADLVTQDRWLVGVVAQSHAVVEHLLDQV
Mvan_1107|M.vanbaalenii_PYR-1 HSVVAVQGPPGTGKTYRAARLIRALVCAG-QRVGVTALSHHAIANVLEGV
TH_3422|M.thermoresistible__bu HSCVAVQGPPGTGKTYRGARMIRALVKAG-KRVGITAISHYAIGNLLEGV
* :**:********. .. :* *: :*:.* :* .: ::: :
MLBr_01098|M.leprae_Br4923 ITAGLDARQVAKKRHDR--SAPPWQEIDGNDYPTFIADP--MGCVIGGTA
MAV_1388|M.avium_104 IDAGLDPRRIAKKRYDR--QAPRWQEIDGNAYAAFLADT--PGCVIGGTA
Mb1283c|M.bovis_AF2122/97 ISAGLDPGQVAKKPHDH--TAGRWQSIDGSQYTEFIRDT--AGCVIGGTA
Rv1251c|M.tuberculosis_H37Rv ISAGLDPGQVAKKPHDH--TAGRWQSIDGSQYTEFIRDT--AGCVIGGTA
MMAR_4191|M.marinum_M IDAGLDPARIAKKRYDH--GAPRWQEIDGNHYAAFIADH--PGCVVGGTA
MUL_4495|M.ulcerans_Agy99 IDAGLDPARIAKKRYDH--GAPRWQEIDSNHYAAFIADH--PGCVVGGTA
Mflv_2223|M.gilvum_PYR-GCK MRAGVDGARVGKKRHTV--STG-WTELGRDDYVDFLCQG---GCVVGGTA
MSMEG_5044|M.smegmatis_MC2_155 IAADVPADAVAKKPHGD--NAC-WTELSEKEYPDFLDQHTGTGCVIGGTA
MAB_1401c|M.abscessus_ATCC_199 VAAGVPADRVAKKASPYS-GDAAWTQIRDSDYARFIADHTGQGAVIGGTA
Mvan_1107|M.vanbaalenii_PYR-1 VKAFTETGELELLHAVCNAGTSSVQRVPGVTYGDNGKCARDEFNVVAGTT
TH_3422|M.thermoresistible__bu VAAFRETDELDSLRAVCNPGKSALRRLPEIAYGGNKKCAREEYNVVAGTT
: * : : * *:.**:
MLBr_01098|M.leprae_Br4923 WDFANRNRVPPGSLDLLVIDEAGQFCLANTIAVAPAAANLMLLGDPQQLP
MAV_1388|M.avium_104 WDFANANRIPPGSLDLLVIDEAGQFCLANTIAVAPAAANLLLLGDPQQLP
Mb1283c|M.bovis_AF2122/97 WDFANGNRVPKASLDLLVIDEAGQFCLANTIAVAPAATNLLLLGDPQQLP
Rv1251c|M.tuberculosis_H37Rv WDFANGNRVPKASLDLLVIDEAGQFCLANTIAVAPAATNLLLLGDPQQLP
MMAR_4191|M.marinum_M WDFANGNRVPPGSLDLLVVDEAGQFCLANTVAVAPAAANLLLLGDPQQLP
MUL_4495|M.ulcerans_Agy99 WDFANGNRVPPGSLDLLVVDEAGQFCLANTVAVAPAAANLLLLGDPQQLP
Mflv_2223|M.gilvum_PYR-GCK WDFANATKFERECLDLLVIEEAGQFSLANTVAVARAARNLMLLGDPQQLP
MSMEG_5044|M.smegmatis_MC2_155 WDFANPVRIPPGSLDLLVVEEAGQYSLANTIAVAPAAHNLLLLGDPQQLP
MAB_1401c|M.abscessus_ATCC_199 WDFANATRVADDALELLVIDEAGQFSLANTLAVARGARNLLLLGDPQQLP
Mvan_1107|M.vanbaalenii_PYR-1 WLFSNA-LMRNAPVDVLLIDEAGQLALADALAASGAAHNLVLLGDPLQLP
TH_3422|M.thermoresistible__bu WLFSSK-EMRAAPVDVLVIDEAGQLALADALAASGAAHNLVLLGDPLQLP
* *:. . :::*:::**** .**:::*.: .* **:***** ***
MLBr_01098|M.leprae_Br4923 QVSQGTHPEPVNTSALDWLVEGQRTLPNERGYFLDRSYRMHPAICAAVST
MAV_1388|M.avium_104 QVSQGTHPEPVDTSALDWLVDGQRTLPDERGYFLDRSYRMHPAVCAAVSA
Mb1283c|M.bovis_AF2122/97 QVSQGTHPEPVDTSALSWLVDGQHTLPDERGYFLDRSYRMHPAVCAAVSA
Rv1251c|M.tuberculosis_H37Rv QVSQGTHPEPVDTSALSWLVDGQHTLPDERGYFLDRSYRMHPAVCAAVSA
MMAR_4191|M.marinum_M QVSQGKHPEPVDVSALEWLVDGQRTLPEERGYFLDRSFRMHPAVCHAVSM
MUL_4495|M.ulcerans_Agy99 QVSEGKHPEPVDVSALEWLVDGQRTLPEERGYFLDRSFRMHPAVCHAVSM
Mflv_2223|M.gilvum_PYR-GCK QVSQGTHPEPVDGSALGWLVDGHATLPPERGYFLDQSFRMHPDVCRAVSR
MSMEG_5044|M.smegmatis_MC2_155 QVSQGTHPEPVDTSALGWLVDGHHTLPAELGYFLDCSYRMHPAVCAAVSR
MAB_1401c|M.abscessus_ATCC_199 QVSQGVHPEPVDTSALGWLVEGHGALPASRGYFLERSYRMHPALCQYVSR
Mvan_1107|M.vanbaalenii_PYR-1 QVAQAKHPGISGRSVLDHVVGDDVLLPPDRGVFLHETRRMHPDVCEFIST
TH_3422|M.thermoresistible__bu QVAHANHPGIAGRSVLDHIVGDDMLLPPDRGVFMHETRRMHPDVCAFISD
**:.. ** . *.* :* .. ** . * *:. : **** :* :*
MLBr_01098|M.leprae_Br4923 LSYEGKLHAHTEYTAARRLNEYQPGVHVLAVHHQGNSTESPEEAGAITAE
MAV_1388|M.avium_104 LSYEGRLHS-DACTAARRLDGCPPGVRLLSVDHQGNSTESPEEADAIAAA
Mb1283c|M.bovis_AF2122/97 LSYEGRLCSHTERTAVRRLDGYPPGVHTRGVHHKGNSIESPEEAEAILAE
Rv1251c|M.tuberculosis_H37Rv LSYEGRLCSHTERTAVRRLDGYPPGVHTRGVHHKGNSIESPEEAEAILAE
MMAR_4191|M.marinum_M LSYAGKLHSHTERTTARRLSASPPGVHVLAVEHQGNSIESAEEAEAILAQ
MUL_4495|M.ulcerans_Agy99 LSYAGKLHSHTERTTARRLSASPPGVHVLAVEHQGNSIESAEEAEAILAQ
Mflv_2223|M.gilvum_PYR-GCK LSYDGRLLSYETVTAARRLDGVAPGVRTLPVSHLGNATESPEEADAIVTE
MSMEG_5044|M.smegmatis_MC2_155 LSYDNRLRSVDDVTAARHLDGQEPGVHVLLVDHDGNATDSPEEAQVIVAE
MAB_1401c|M.abscessus_ATCC_199 LSYDGELES---AAPERSLAGQPPGVRTLLVDHEGNATSSPQEAEAIATE
Mvan_1107|M.vanbaalenii_PYR-1 QIYDGRLHSFPDCGRQSTVAG--TGLRWLRVDHAGNRTFSVQEADAIAQE
TH_3422|M.thermoresistible__bu QIYDGRLHSISDCNRQTTVAG--TGLRWMRVDHHGNRTRSPEEADAIADE
* ..* : : .*:: * * ** * :** .*
MLBr_01098|M.leprae_Br4923 IERLLGTPWTDEH-----GTRPLDVSDILVLAPYNAQVALVRQQLMSAGF
MAV_1388|M.avium_104 VTGLLGASWTDEH-----GTRALTASDVLVLAPYNAQVALLRRRLGSAGL
Mb1283c|M.bovis_AF2122/97 LRQLLGSPWTDEH-----GTRPLAASDVLVLAPYNAQVALVRRRLASAGL
Rv1251c|M.tuberculosis_H37Rv LRQLLGSPWTDEH-----GTRPLAASDVLVLAPYNAQVALVRRRLASAGL
MMAR_4191|M.marinum_M IQRLLGSPWTDEH-----GTRPLATHDLLVLAPYNAQVALIRQRLLSAGL
MUL_4495|M.ulcerans_Agy99 IQRLLGSPWTDEH-----GTRPLATRDLLVLAPYNAQVALIRQRLLSAGL
Mflv_2223|M.gilvum_PYR-GCK IRRLLGAAWTDAASTDTDATRPLDQTDVLIVTPYNAQVVLLRRRLDAAGL
MSMEG_5044|M.smegmatis_MC2_155 IRRLLGAAWTDER-----GTVPLGQDHVLVVTPYNAQVVTMRRYLDAAGL
MAB_1401c|M.abscessus_ATCC_199 IARLIGSDWTDES-----GTRPLEQSDVLVVAPYNAQVLTLRATLAAAGL
Mvan_1107|M.vanbaalenii_PYR-1 LSRLIDTPWTNHKG----ETERLQAGDFMVVAPYNLQVNTTHARLAQDAA
TH_3422|M.thermoresistible__bu LTRLIGTPWTNQCG----EEAPLRPQDVMVVAPYNLQVNTIRARLRQDPR
: *:.: **: * ..::::*** ** : *
MLBr_01098|M.leprae_Br4923 S---GVRVGTVDKFQGGQAPVVFISMTSSSVEVVPRGISFLLNRNRLNVA
MAV_1388|M.avium_104 D---GVRVGTVDKFQGGQAPVVFISMTASSVDVVPRGISFLLNRNRLNVA
Mb1283c|M.bovis_AF2122/97 GGADGVRVGTVDKFQGGQAPVVFISMTASSADDVPRGISFLLNRNRLNVA
Rv1251c|M.tuberculosis_H37Rv GGADGVRVGTVDKFQGGQAPVVFISMTASSADDVPRGISFLLNRNRLNVA
MMAR_4191|M.marinum_M N---GVRVGTVDKFQGAQAPVVFVSMTASAVDDVPRGISFLLNRNRLNVA
MUL_4495|M.ulcerans_Agy99 N---GVRVGTVDKFQGAQAPVVFVSMTASSVDDVPRGISFLLNRNRLNVA
Mflv_2223|M.gilvum_PYR-GCK T---RVRAGTVDKFQGQQAPVVFVSMTASSIDDVPRGISFLLNRNRLNVA
MSMEG_5044|M.smegmatis_MC2_155 T---DVRVGTVDKFQGQQAPVVFISMVASSVDDVPRGISFLLNRNRLNVA
MAB_1401c|M.abscessus_ATCC_199 G---EVLVGTVDKFQGRQAPVVFVSMTASAVDDVPRGMSFLLNRNRLNVA
Mvan_1107|M.vanbaalenii_PYR-1 LR--DVPVGTVDKFQGREAAVVFFSMAASSGEDITRGVEFLFSRNRLNVA
TH_3422|M.thermoresistible__bu LA--DVPVGTVDKFQGREAAVVFFSMASSSGEDISRGVDFLLSRNRLNVA
* .******** :*.***.**.:*: : :.**:.**:.*******
MLBr_01098|M.leprae_Br4923 VSRAQYAAVIVRSETLTEYLPATPVGLIDLGAFLTLTTFNGTGRLESRLD
MAV_1388|M.avium_104 VSRAQYAAVIVRSPTLTEYLPGTPAGLIELGAFLALTQPDLR--------
Mb1283c|M.bovis_AF2122/97 VSRAQYAAVIVRSELLTQYLPATPDGLVDLGAFLGLTSTS----------
Rv1251c|M.tuberculosis_H37Rv VSRAQYAAVIVRSELLTQYLPATPDGLVDLGAFLGLTSTS----------
MMAR_4191|M.marinum_M ISRAQYAAVIVRSELLTRYLPGTPAGLVDLGAFLALTEPG----------
MUL_4495|M.ulcerans_Agy99 ISRAQYAAVIVRSELLTRYLPGTPAGLVDLGAFLALTEPA----------
Mflv_2223|M.gilvum_PYR-GCK VSRAKYLAVVVRSEHLTDYLPGTPDRLVELGAFLSLTSGTAGVPGSVACD
MSMEG_5044|M.smegmatis_MC2_155 VSRAKYAAVIVRSAALTEYLPSTPAGVVELGAFLALPDALPDALNTV---
MAB_1401c|M.abscessus_ATCC_199 ISRAKFQAVIVRSPALTEYLPTTPDGLVELGAFLALSPDKTFS-------
Mvan_1107|M.vanbaalenii_PYR-1 VSRARCLAYLVCTDALLDTRARTVEEMRLISTLNAFVDTAALHESREV--
TH_3422|M.thermoresistible__bu VSRARCLAYLVCTDALLDTRARTVEDMRLVATLNAFVEAAQPVTPVPSTA
:***: * :* : * . * : :.:: :
MLBr_01098|M.leprae_Br4923 KP---
MAV_1388|M.avium_104 -----
Mb1283c|M.bovis_AF2122/97 -----
Rv1251c|M.tuberculosis_H37Rv -----
MMAR_4191|M.marinum_M -----
MUL_4495|M.ulcerans_Agy99 -----
Mflv_2223|M.gilvum_PYR-GCK DRHRS
MSMEG_5044|M.smegmatis_MC2_155 -----
MAB_1401c|M.abscessus_ATCC_199 -----
Mvan_1107|M.vanbaalenii_PYR-1 -----
TH_3422|M.thermoresistible__bu GC---