For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
CQPRDRRPVRPRCAFTCHRWRAMPSWIADLVSLDGDGETFCSTASFGAGNRLFGGLIAAQALAAAGATVE SARLPQSLHAYFIKGGRVGVDVEYVVERTRDGKSFNTRRVTASQDGVAIFEMLVSFHRSEPTADWQRSRQ PTIARSAVTKATRLPERWADHFEVLTARDGMDDWPVQPMWFRSRQPVEDDPLLRACALTLISDVGLVAVA RPPGEAQLPGPGGAASLDHAVWLHRPFDPHQWHLYDAEAVSHNDARGLARGSIVDEHGTLVASVAQESLW RI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1008 | - | - | 100% (283) | acyl-CoA thioesterase |
| M. vanbaalenii PYR-1 | Mvan_2250 | - | 9e-74 | 53.67% (259) | acyl-CoA thioesterase |
| M. vanbaalenii PYR-1 | Mvan_2565 | - | 1e-29 | 35.92% (245) | acyl-CoA thioesterase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2637c | tesB2 | 2e-31 | 34.92% (252) | acyl-CoA thioesterase II |
| M. gilvum PYR-GCK | Mflv_4093 | - | 2e-70 | 50.97% (259) | acyl-CoA thioesterase |
| M. tuberculosis H37Rv | Rv2605c | tesB2 | 3e-32 | 35.32% (252) | acyl-CoA thioesterase II |
| M. leprae Br4923 | MLBr_01278 | tesB | 2e-18 | 26.91% (249) | acyl CoA thioesterase II |
| M. abscessus ATCC 19977 | MAB_2891c | - | 8e-36 | 38.27% (243) | acyl-CoA thioesterase II TesB2 |
| M. marinum M | MMAR_2095 | tesB2 | 4e-31 | 37.19% (242) | acyl-CoA thioesterase II TesB2 |
| M. avium 104 | MAV_3483 | tesB | 2e-31 | 35.77% (246) | acyl-CoA thioesterase II |
| M. smegmatis MC2 155 | MSMEG_6208 | - | 1e-74 | 52.49% (261) | palmitoyl-CoA hydrolase |
| M. thermoresistible (build 8) | TH_2056 | tesB2 | 1e-32 | 35.71% (280) | PROBABLE ACYL-CoA THIOESTERASE II TESB2 (TEII) |
| M. ulcerans Agy99 | MUL_3249 | tesB2 | 3e-31 | 37.19% (242) | acyl-CoA thioesterase II TesB2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4093|M.gilvum_PYR-GCK MTG-------------------VKLSWISQFLQFERRGDTFVTTPPEVAP
MSMEG_6208|M.smegmatis_MC2_155 MS---------------------APSWIKGLLAFERDGDVFCIREPEPNT
Mvan_1008|M.vanbaalenii_PYR-1 MCQPRDRRPVRPRCAFTCHRWRAMPSWIADLVSLDGDGETFCSTAS-FGA
Mb2637c|M.bovis_AF2122/97 ----------------------MSIEEILDLEQLEVNIYRGSVFSPESGF
Rv2605c|M.tuberculosis_H37Rv ----------------------MSIEEILDLEQLEVNIYRGSVFSPESGF
MAV_3483|M.avium_104 ----------------------MSIEQILDLEQLEVNIYRGGVFSPDSGY
MMAR_2095|M.marinum_M ----------------------MAIEEILDLEQLEVNIYRGSVFSPESGF
MUL_3249|M.ulcerans_Agy99 ----------------------MAIEEILDLEQLEVNIYRGSVFSPESGF
TH_2056|M.thermoresistible__bu ----------------------MAIEEILDLEQLEVNIYRGKVFSPESGF
MAB_2891c|M.abscessus_ATCC_199 ---------------------MADIEEILTLEQLEKDIFRGNVTPSN---
MLBr_01278|M.leprae_Br4923 ------------MKRLWEKKTMSDFEELLAVLDLNRVADDLFIGSHPSKN
. : . ::
Mflv_4093|M.gilvum_PYR-GCK GLRLFGGLIAAQALGAAGATVD-PGKHPQSLHLYFVRGGRYDADVELQVE
MSMEG_6208|M.smegmatis_MC2_155 IERLFGGLIAAQSLGAAGATVD-DDKVPQSLHAYFVRGGRYDTDVEFRVT
Mvan_1008|M.vanbaalenii_PYR-1 GNRLFGGLIAAQALAAAGATVE-SARLPQSLHAYFIKGGRVGVDVEYVVE
Mb2637c|M.bovis_AF2122/97 LQRTFGGHVAGQSLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVE
Rv2605c|M.tuberculosis_H37Rv LQRTFGGHVAGQSLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVE
MAV_3483|M.avium_104 FQRTFGGHVAGQSLVSAVRTVD-PRYQVHSLHGYFLRPGDAKERTVFIVE
MMAR_2095|M.marinum_M LQRTFGGHVAGQSLVSAVRTVD-PRYQVHSLHGYFLRSGDAQEPTVFLVE
MUL_3249|M.ulcerans_Agy99 LQRTFGGHVAGQSLVSAVRTVD-PRYQVHSLHGYFLRSGDAQEPTVFLVE
TH_2056|M.thermoresistible__bu LQRTFGGHVAGQSLVSAVRTVD-PKFQVHSLHGYFLLPGDARAPTVYFVE
MAB_2891c|M.abscessus_ATCC_199 LRRTFGGQVAGQSLVSAVRTVE-PEYLVHSLHGYFLRPGNPNEPTVFLVD
MLBr_01278|M.leprae_Br4923 PLRTFGGQLVAQSFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVV
* *** :..*:: :: *: :: :*: * *
Mflv_4093|M.gilvum_PYR-GCK RTRDGRSFDTRRVTAVQQGAVILEMIASFHTPEPGADEFPPHPPSVTLDE
MSMEG_6208|M.smegmatis_MC2_155 RIRDGRAFATRQVSASQDGKVILEMIASFHAPEPGVDWQPRTEPRLEFDA
Mvan_1008|M.vanbaalenii_PYR-1 RTRDGKSFNTRRVTASQDGVAIFEMLVSFHRSEPTADWQRSRQPTIARSA
Mb2637c|M.bovis_AF2122/97 RIRDGGSLCTRRVNAVQHGETIFSMAASFQTEQEGITHQDVMPAAPPPDG
Rv2605c|M.tuberculosis_H37Rv RIRDGGSFCTRRVNAVQHGETIFSMAASFQTEQEGITHQDVMPAAPPPDG
MAV_3483|M.avium_104 RTRDGGSFATRRVNAIQHGEIIFSMGASFQTDQEGIHHQDAMPAAPPPDG
MMAR_2095|M.marinum_M RTRDGGSFVTRRVNAVQHGEVIFSMGASFQTAQNGISHQDAMPAAPPPDD
MUL_3249|M.ulcerans_Agy99 RTRDGGSFVTRRVNAVQHGEVIFSMGASFQTAQNGISHQDAMPAAPPPDD
TH_2056|M.thermoresistible__bu RLRDGGSFCTRRVSAIQHGEVIFSMSASFQTDQSGIEHQDAMPEAPPPDD
MAB_2891c|M.abscessus_ATCC_199 RVRDGRSFVTRRVTAIQDGQAIFSMSASFQTLDTGIEHQDLMPPVPDPED
MLBr_01278|M.leprae_Br4923 RLRDERRFANRRVDAIQDGMLLSSAMASYMSGGCGLEHAVEPPEAAEPHT
* ** : .*:* * *.* : . .*:
Mflv_4093|M.gilvum_PYR-GCK TESME-------PDVEFTD------LFEIRTGPGD-----PSIFVTPPFW
MSMEG_6208|M.smegmatis_MC2_155 AVPKD-------PEIDFSD------AFEVRTRTSD-----DSEFAVPPFW
Mvan_1008|M.vanbaalenii_PYR-1 VTKATR------LPERWAD------HFEVLTARDG-----MDDWPVQPMW
Mb2637c|M.bovis_AF2122/97 LPGLNSIKVFDDAGFRQFD------EWDVCIVPRERLRLLPGKASQQQVW
Rv2605c|M.tuberculosis_H37Rv LPGLNSIKVFDDAGFRQFD------EWDVCIVPRERLRLLPGKASQQQVW
MAV_3483|M.avium_104 LPGLDSIKVFDDAGFKQFE------EWDVCIVPREKLQLTPGKASQQQVW
MMAR_2095|M.marinum_M LPGLRSVRVFDDAGFRQFE------EWDVRIVPRDLLAPLPGKASQQQVW
MUL_3249|M.ulcerans_Agy99 LPGLRSVRVFDDAGFRQFE------EWDVRIVPRDLLAPLPGKASQQQVW
TH_2056|M.thermoresistible__bu LPGFRSARAFDDAGFAQFD------EWDVRVVPRDKLKRVAGKASQQQVW
MAB_2891c|M.abscessus_ATCC_199 LPDAQEQDSFNRDLFRQFA------EWDIRIVPDELMDRNPRLAAQQRVW
MLBr_01278|M.leprae_Br4923 RPPIGELLRGYEQIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVW
: .*
Mflv_4093|M.gilvum_PYR-GCK IRSREQVEDDPLIRACALTFLSDFGPVPAAHPQH-TPLRPGTGQAASLDH
MSMEG_6208|M.smegmatis_MC2_155 IRTREPVEDDPLVRACALTYMSDLGPVPTALPPT-VPLRPDLGFATSLDH
Mvan_1008|M.vanbaalenii_PYR-1 FRSRQPVEDDPLLRACALTLISDVGLVAVARPPG-EAQLPGPGGAASLDH
Mb2637c|M.bovis_AF2122/97 LRHRDPLPDDPVLHICALAYMSDLTLLGSAQVNH-LDVRDQLQVAS-LDH
Rv2605c|M.tuberculosis_H37Rv LRHRDPLPDDPVLHICALAYMSDLTLLGSAQVNH-LDVRDQLQVAS-LDH
MAV_3483|M.avium_104 FRHRDPLPDDPVLHICALAYMSDLTLLGSAQVTH-LDVREHLQVAS-LDH
MMAR_2095|M.marinum_M FRHRDPLPDDPVLHICALAYMSDLTLLGSAQVTH-LAEREHLQVAS-LDH
MUL_3249|M.ulcerans_Agy99 FRHRDPLPDDPVLHICALAYMSDLTLLGSAQVTH-LAEREHLQVAS-LDH
TH_2056|M.thermoresistible__bu FRHRDPLPDDPVLHICALAYMSDLTLLGSAQVNH-VAERPHLQVAS-LDH
MAB_2891c|M.abscessus_ATCC_199 FRCRKHLPDDPVLHICALAYMSDLTLLSSSKVPH-RDT--VLQTAS-LDH
MLBr_01278|M.leprae_Br4923 VKALGALPNDPTLHTAAMLYSTDTTVLDSVITTHGLSWGFDRIFAVSANH
.: : :** :: .*: :* : * :*
Mflv_4093|M.gilvum_PYR-GCK SVWFHRPFDPHEWHRYEVHPLNVGDSRGLVHGSLYDGSGSLVATTTQEAL
MSMEG_6208|M.smegmatis_MC2_155 SIWFHRPFRPDIWHRYELRAANHNDSRGLTTGSLIDESGTLIASVCQEAL
Mvan_1008|M.vanbaalenii_PYR-1 AVWLHRPFDPHQWHLYDAEAVSHNDARGLARGSIVDEHGTLVASVAQESL
Mb2637c|M.bovis_AF2122/97 AMWFMRPFRADEWLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQEGL
Rv2605c|M.tuberculosis_H37Rv AMWFMRPFRADEWLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQEGL
MAV_3483|M.avium_104 AMWFMRAFRADEWLLYDQSSPSANGGRSLCQGKIFTQSGEMVAAVMQEGL
MMAR_2095|M.marinum_M AMWFMRGFRADEWLLYDQSSPSAGGGRALTHGKIFTQGGELVAAVMQEGL
MUL_3249|M.ulcerans_Agy99 AMWFMRGFRADEWLLYDQSSPSAGGGRALTHGKIFTQGGELVAAVMQEGL
TH_2056|M.thermoresistible__bu AMWFMRPFRADEWLLYDQSSPSACGGRALTQGQIFNQYGEMVAAVMQEGL
MAB_2891c|M.abscessus_ATCC_199 ALWFLRPFRADEWMLYDETSPSAGFGRALTQGRIFNRDGTMVAAVVQEGL
MLBr_01278|M.leprae_Br4923 SVWFHRQVNFDDWVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQEGV
::*: * . . * *. . .*.* * : * ::*:. **.:
Mflv_4093|M.gilvum_PYR-GCK WRL-------------------
MSMEG_6208|M.smegmatis_MC2_155 WRLDIS----------------
Mvan_1008|M.vanbaalenii_PYR-1 WRI-------------------
Mb2637c|M.bovis_AF2122/97 TRHRRGHRSVGQ----------
Rv2605c|M.tuberculosis_H37Rv TRHRRGHRSVGQ----------
MAV_3483|M.avium_104 TRFQRGYRQ-------------
MMAR_2095|M.marinum_M TRYPSGYQPGEK----------
MUL_3249|M.ulcerans_Agy99 TRYPSGYQPGEN----------
TH_2056|M.thermoresistible__bu TRYPRNFTRTQQIQTEQTQTRP
MAB_2891c|M.abscessus_ATCC_199 TRIERNPEQASVARGNMA----
MLBr_01278|M.leprae_Br4923 LKYFPASHR-------------
: