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MTGVKLSWISQFLQFERRGDTFVTTPPEVAPGLRLFGGLIAAQALGAAGATVDPGKHPQSLHLYFVRGGR YDADVELQVERTRDGRSFDTRRVTAVQQGAVILEMIASFHTPEPGADEFPPHPPSVTLDETESMEPDVEF TDLFEIRTGPGDPSIFVTPPFWIRSREQVEDDPLIRACALTFLSDFGPVPAAHPQHTPLRPGTGQAASLD HSVWFHRPFDPHEWHRYEVHPLNVGDSRGLVHGSLYDGSGSLVATTTQEALWRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4093 | - | - | 100% (264) | acyl-CoA thioesterase |
| M. gilvum PYR-GCK | Mflv_3831 | - | 1e-32 | 35.52% (259) | acyl-CoA thioesterase II |
| M. gilvum PYR-GCK | Mflv_1022 | - | 4e-30 | 34.72% (265) | acyl-CoA thioesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2637c | tesB2 | 1e-34 | 37.55% (261) | acyl-CoA thioesterase II |
| M. tuberculosis H37Rv | Rv2605c | tesB2 | 2e-35 | 37.93% (261) | acyl-CoA thioesterase II |
| M. leprae Br4923 | MLBr_01278 | tesB | 2e-21 | 29.17% (264) | acyl CoA thioesterase II |
| M. abscessus ATCC 19977 | MAB_2891c | - | 2e-36 | 37.96% (245) | acyl-CoA thioesterase II TesB2 |
| M. marinum M | MMAR_2095 | tesB2 | 1e-36 | 39.15% (258) | acyl-CoA thioesterase II TesB2 |
| M. avium 104 | MAV_3483 | tesB | 6e-35 | 36.23% (276) | acyl-CoA thioesterase II |
| M. smegmatis MC2 155 | MSMEG_6208 | - | 6e-91 | 62.79% (258) | palmitoyl-CoA hydrolase |
| M. thermoresistible (build 8) | TH_2056 | tesB2 | 4e-35 | 38.37% (258) | PROBABLE ACYL-CoA THIOESTERASE II TESB2 (TEII) |
| M. ulcerans Agy99 | MUL_3249 | tesB2 | 7e-37 | 39.15% (258) | acyl-CoA thioesterase II TesB2 |
| M. vanbaalenii PYR-1 | Mvan_2250 | - | 1e-116 | 74.90% (263) | acyl-CoA thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4093|M.gilvum_PYR-GCK -------MTGVKLSWISQFLQFERRGDTFVTTPPEVAPGLRLFGGLIAAQ
Mvan_2250|M.vanbaalenii_PYR-1 -------MTGVEKSWIADLLRFDRRDDVFVACPTAAGPGSRLFGGLIAAQ
MSMEG_6208|M.smegmatis_MC2_155 -------MS--APSWIKGLLAFERDGDVFCIREPEPNTIERLFGGLIAAQ
Mb2637c|M.bovis_AF2122/97 ----------MSIEEILDLEQLEVNIYRGSVFSPESGFLQRTFGGHVAGQ
Rv2605c|M.tuberculosis_H37Rv ----------MSIEEILDLEQLEVNIYRGSVFSPESGFLQRTFGGHVAGQ
MAV_3483|M.avium_104 ----------MSIEQILDLEQLEVNIYRGGVFSPDSGYFQRTFGGHVAGQ
MMAR_2095|M.marinum_M ----------MAIEEILDLEQLEVNIYRGSVFSPESGFLQRTFGGHVAGQ
MUL_3249|M.ulcerans_Agy99 ----------MAIEEILDLEQLEVNIYRGSVFSPESGFLQRTFGGHVAGQ
TH_2056|M.thermoresistible__bu ----------MAIEEILDLEQLEVNIYRGKVFSPESGFLQRTFGGHVAGQ
MAB_2891c|M.abscessus_ATCC_199 ---------MADIEEILTLEQLEKDIFRGNVTPSN---LRRTFGGQVAGQ
MLBr_01278|M.leprae_Br4923 MKRLWEKKTMSDFEELLAVLDLNRVADDLFIGSHPSKNPLRTFGGQLVAQ
. : . :: * *** :..*
Mflv_4093|M.gilvum_PYR-GCK ALGAAGATVD-PGKHPQSLHLYFVRGGRYDADVELQVERTRDGRSFDTRR
Mvan_2250|M.vanbaalenii_PYR-1 SLGAAGATVG-AGKLPQSLHLYFVRGGRYGVEVELHVERTRDGRSFDTRR
MSMEG_6208|M.smegmatis_MC2_155 SLGAAGATVD-DDKVPQSLHAYFVRGGRYDTDVEFRVTRIRDGRAFATRQ
Mb2637c|M.bovis_AF2122/97 SLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVERIRDGGSLCTRR
Rv2605c|M.tuberculosis_H37Rv SLVSAVRTVD-PRYMVHSLHGYFLRPGDAKERTVFLVERIRDGGSFCTRR
MAV_3483|M.avium_104 SLVSAVRTVD-PRYQVHSLHGYFLRPGDAKERTVFIVERTRDGGSFATRR
MMAR_2095|M.marinum_M SLVSAVRTVD-PRYQVHSLHGYFLRSGDAQEPTVFLVERTRDGGSFVTRR
MUL_3249|M.ulcerans_Agy99 SLVSAVRTVD-PRYQVHSLHGYFLRSGDAQEPTVFLVERTRDGGSFVTRR
TH_2056|M.thermoresistible__bu SLVSAVRTVD-PKFQVHSLHGYFLLPGDARAPTVYFVERLRDGGSFCTRR
MAB_2891c|M.abscessus_ATCC_199 SLVSAVRTVE-PEYLVHSLHGYFLRPGNPNEPTVFLVDRVRDGRSFVTRR
MLBr_01278|M.leprae_Br4923 SFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVVRLRDERRFANRR
:: :: *: :: :*: * * * ** : .*:
Mflv_4093|M.gilvum_PYR-GCK VTAVQQGAVILEMIASFHTPEPGADEFPPHPPSVTLDETESMEPDVEFTD
Mvan_2250|M.vanbaalenii_PYR-1 VTAVQQGAVILEMIASFHTPEPGADEHPSPPSSVTLADARVKEPDIEFAD
MSMEG_6208|M.smegmatis_MC2_155 VSASQDGKVILEMIASFHAPEPGVDWQPRTEPRLEFDAAVPKDPEIDFSD
Mb2637c|M.bovis_AF2122/97 VNAVQHGETIFSMAASFQTEQEGITHQDVMPAAPPPDGLPGLNSIKVFDD
Rv2605c|M.tuberculosis_H37Rv VNAVQHGETIFSMAASFQTEQEGITHQDVMPAAPPPDGLPGLNSIKVFDD
MAV_3483|M.avium_104 VNAIQHGEIIFSMGASFQTDQEGIHHQDAMPAAPPPDGLPGLDSIKVFDD
MMAR_2095|M.marinum_M VNAVQHGEVIFSMGASFQTAQNGISHQDAMPAAPPPDDLPGLRSVRVFDD
MUL_3249|M.ulcerans_Agy99 VNAVQHGEVIFSMGASFQTAQNGISHQDAMPAAPPPDDLPGLRSVRVFDD
TH_2056|M.thermoresistible__bu VSAIQHGEVIFSMSASFQTDQSGIEHQDAMPEAPPPDDLPGFRSARAFDD
MAB_2891c|M.abscessus_ATCC_199 VTAIQDGQAIFSMSASFQTLDTGIEHQDLMPPVPDPEDLPDAQEQDSFNR
MLBr_01278|M.leprae_Br4923 VDAIQDGMLLSSAMASYMSGGCGLEHAVEPPEAAEPHTRPPIGELLRGYE
* * *.* : . **: : *
Mflv_4093|M.gilvum_PYR-GCK L-------------FEIRTGPGD-----PSIFVTPPFWIRSREQVEDDPL
Mvan_2250|M.vanbaalenii_PYR-1 R-------------FEIRTQLDD-----DSVFAVPPFWIRTRDEIEDDPL
MSMEG_6208|M.smegmatis_MC2_155 A-------------FEVRTRTSD-----DSEFAVPPFWIRTREPVEDDPL
Mb2637c|M.bovis_AF2122/97 AGFRQFD------EWDVCIVPRERLRLLPGKASQQQVWLRHRDPLPDDPV
Rv2605c|M.tuberculosis_H37Rv AGFRQFD------EWDVCIVPRERLRLLPGKASQQQVWLRHRDPLPDDPV
MAV_3483|M.avium_104 AGFKQFE------EWDVCIVPREKLQLTPGKASQQQVWFRHRDPLPDDPV
MMAR_2095|M.marinum_M AGFRQFE------EWDVRIVPRDLLAPLPGKASQQQVWFRHRDPLPDDPV
MUL_3249|M.ulcerans_Agy99 AGFRQFE------EWDVRIVPRDLLAPLPGKASQQQVWFRHRDPLPDDPV
TH_2056|M.thermoresistible__bu AGFAQFD------EWDVRVVPRDKLKRVAGKASQQQVWFRHRDPLPDDPV
MAB_2891c|M.abscessus_ATCC_199 DLFRQFA------EWDIRIVPDELMDRNPRLAAQQRVWFRCRKHLPDDPV
MLBr_01278|M.leprae_Br4923 QIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVWVKALGALPNDPT
: .*.: : :**
Mflv_4093|M.gilvum_PYR-GCK IRACALTFLSDFGPVPAAHPQH-TPLRPGTGQAASLDHSVWFHRPFDPHE
Mvan_2250|M.vanbaalenii_PYR-1 VRACMLTFLSDFGPVPVARPSG-TPLEPEAGFAASLDHSVWFHRPFTPHD
MSMEG_6208|M.smegmatis_MC2_155 VRACALTYMSDLGPVPTALPPT-VPLRPDLGFATSLDHSIWFHRPFRPDI
Mb2637c|M.bovis_AF2122/97 LHICALAYMSDLTLLGSAQVNH-LDVRDQLQVAS-LDHAMWFMRPFRADE
Rv2605c|M.tuberculosis_H37Rv LHICALAYMSDLTLLGSAQVNH-LDVRDQLQVAS-LDHAMWFMRPFRADE
MAV_3483|M.avium_104 LHICALAYMSDLTLLGSAQVTH-LDVREHLQVAS-LDHAMWFMRAFRADE
MMAR_2095|M.marinum_M LHICALAYMSDLTLLGSAQVTH-LAEREHLQVAS-LDHAMWFMRGFRADE
MUL_3249|M.ulcerans_Agy99 LHICALAYMSDLTLLGSAQVTH-LAEREHLQVAS-LDHAMWFMRGFRADE
TH_2056|M.thermoresistible__bu LHICALAYMSDLTLLGSAQVNH-VAERPHLQVAS-LDHAMWFMRPFRADE
MAB_2891c|M.abscessus_ATCC_199 LHICALAYMSDLTLLSSSKVPH-RDT--VLQTAS-LDHALWFLRPFRADE
MLBr_01278|M.leprae_Br4923 LHTAAMLYSTDTTVLDSVITTHGLSWGFDRIFAVSANHSVWFHRQVNFDD
:: . : : :* : * :*::** * . .
Mflv_4093|M.gilvum_PYR-GCK WHRYEVHPLNVGDSRGLVHGSLYDGSGSLVATTTQEALWRL---------
Mvan_2250|M.vanbaalenii_PYR-1 WHRYEVHQLNVGDSRGLVRGSLYDAEGSLIATTTQEALWRC---------
MSMEG_6208|M.smegmatis_MC2_155 WHRYELRAANHNDSRGLTTGSLIDESGTLIASVCQEALWRLDIS------
Mb2637c|M.bovis_AF2122/97 WLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQEGLTRHRRGHRSVGQ
Rv2605c|M.tuberculosis_H37Rv WLLYDQSSPSASGGRALTRGEIFTRSGEMVAAVMQEGLTRHRRGHRSVGQ
MAV_3483|M.avium_104 WLLYDQSSPSANGGRSLCQGKIFTQSGEMVAAVMQEGLTRFQRGYRQ---
MMAR_2095|M.marinum_M WLLYDQSSPSAGGGRALTHGKIFTQGGELVAAVMQEGLTRYPSGYQPGEK
MUL_3249|M.ulcerans_Agy99 WLLYDQSSPSAGGGRALTHGKIFTQGGELVAAVMQEGLTRYPSGYQPGEN
TH_2056|M.thermoresistible__bu WLLYDQSSPSACGGRALTQGQIFNQYGEMVAAVMQEGLTRYPRNFTRTQQ
MAB_2891c|M.abscessus_ATCC_199 WMLYDETSPSAGFGRALTQGRIFNRDGTMVAAVVQEGLTRIERNPEQASV
MLBr_01278|M.leprae_Br4923 WVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQEGVLKYFPASHR---
* *. .*.* * : * ::*:. **.: :
Mflv_4093|M.gilvum_PYR-GCK ----------
Mvan_2250|M.vanbaalenii_PYR-1 ----------
MSMEG_6208|M.smegmatis_MC2_155 ----------
Mb2637c|M.bovis_AF2122/97 ----------
Rv2605c|M.tuberculosis_H37Rv ----------
MAV_3483|M.avium_104 ----------
MMAR_2095|M.marinum_M ----------
MUL_3249|M.ulcerans_Agy99 ----------
TH_2056|M.thermoresistible__bu IQTEQTQTRP
MAB_2891c|M.abscessus_ATCC_199 ARGNMA----
MLBr_01278|M.leprae_Br4923 ----------