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VIPVGVLVVAKAPVPGLAKTRLAAALGADVAADIAAAALLDTLDAVADCPAAAKVVALTGNLDDARCADE IRSRLDNFIVIGQRGADLAERLVHAHRDAAAATGGLPIVQIGMDTPQVSPELLERCAQSLLGSDAVLGLA GDGGWWVLGVRDAGFAECLRNVPMSTPDTGAVTLAALQDTDIHVELVCELVDVDTIDDVGAVRAGCGPGS RFSRATAGVGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0887 | - | - | 100% (221) | hypothetical protein Mvan_0887 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0554 | - | 1e-67 | 62.56% (219) | hypothetical protein Mb0554 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0540 | - | 1e-67 | 62.56% (219) | hypothetical protein Rv0540 |
| M. leprae Br4923 | MLBr_00961 | metE | 4e-05 | 32.99% (97) | 5-methyltetrahydropteroyltriglutamate--homocysteine |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0886 | - | 2e-68 | 61.64% (219) | hypothetical protein MMAR_0886 |
| M. avium 104 | MAV_4604 | - | 1e-67 | 62.73% (220) | hypothetical protein MAV_4604 |
| M. smegmatis MC2 155 | MSMEG_0996 | - | 5e-76 | 67.58% (219) | hypothetical protein MSMEG_0996 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0639 | - | 6e-68 | 61.19% (219) | hypothetical protein MUL_0639 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 MDELVTTQSFTATVTGSPRIGPRRELKRATEGYWAKRTSRSELESVASTL
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 RRDMWSDLAAAGLDSVPVNTFSYYDQMLDTAFMLGALPARVAQVSDDLDQ
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 YFALARGNNDIKPLEMTKWFDTNYHYLVPEIEPATTFSLNPGKILGELKE
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 ALEQRIPSRPVIIGPVTFLLLSKGINGGGAPIQRLEELVGIYCTLLSLLA
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 ENGARWVQFDEPALVTDLSPDAPALAEAVYTALGSVSKRPAIYVATYFGN
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 PGASLAGLARTPIEAIGVDFVCGADTSVAAVPELAGKTLVAGIVDGRNIW
Mvan_0887|M.vanbaalenii_PYR-1 ----------------------------MIPVGVLVVAKAPVPGLAKTRL
MSMEG_0996|M.smegmatis_MC2_155 ----------------------------MLAVTVLVVAKAPVPGLAKTRL
MMAR_0886|M.marinum_M --------------------------MSHVPVTLLVVAKAPEPGLAKTRL
MUL_0639|M.ulcerans_Agy99 --------------------------MSHVPVTLLVVAKAPEPGLAKTRL
MAV_4604|M.avium_104 ----------------------------MIPVTLLVVAKAPEPGRAKTRL
Mb0554|M.bovis_AF2122/97 --------------------------MSCLPVSVLVVAKAPEPGRVKTRL
Rv0540|M.tuberculosis_H37Rv --------------------------MSCLPVSVLVVAKAPEPGRVKTRL
MLBr_00961|M.leprae_Br4923 RTDLESALSKLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDNLRSWL
: * : .:: . :: *
Mvan_0887|M.vanbaalenii_PYR-1 AAALGADVAADIAAAALLDTLDAVADCPAAAKVVALTGNLDDARCADEIR
MSMEG_0996|M.smegmatis_MC2_155 AAGVGADVAADIAAAALLDTLDAVAGAPVAHRVVAMTGDLAEACRGREIA
MMAR_0886|M.marinum_M AATVGDQTAADIAAAALLDTLDAVAATPAASRVVALTGDLANAARGAEIR
MUL_0639|M.ulcerans_Agy99 AATVGDQTAADIAAAALLDTLDAVAATPAASRVVALTGDLANAARGAEIR
MAV_4604|M.avium_104 AAAVGERAAAEIAAAALLDTLDAVAAAPVAATVVALTGDLDGAARGAEIR
Mb0554|M.bovis_AF2122/97 AAAIGDKVAADIAAAALLDTLDAVAAAPVTARAVALTGDLDSAADSAEIR
Rv0540|M.tuberculosis_H37Rv AAAIGDKVAADIAAAALLDTLDAVAAAPVTARAVALTGDLDSAADSAEIR
MLBr_00961|M.leprae_Br4923 AFGAEKVAEVVVLARALRDGRDAVADEIAASNAAVASRRSDPRLHNGQVR
* . . : * ** * **** .: ... : ::
Mvan_0887|M.vanbaalenii_PYR-1 SRLDNFIVIGQRGADLAERLVHAHRDAAAATGGLPIVQIG----------
MSMEG_0996|M.smegmatis_MC2_155 DRLADFTVVAQRGDGFAERLVHAHSDAARP--GFPVLQIG----------
MMAR_0886|M.marinum_M QRLESFTVIGQRGDDFADRLANAHADAADG---YPVLQVG----------
MUL_0639|M.ulcerans_Agy99 RRLESFTVIGQRGDDFADRLANAHADAADG---YPVLQVG----------
MAV_4604|M.avium_104 ARLASFTVIAQRGNDFGARLANAHADAADG---LPVLQIG----------
Mb0554|M.bovis_AF2122/97 RRLKSFTVFRQRGDAFADRLANAHVDAADG---YPVLQIG----------
Rv0540|M.tuberculosis_H37Rv RRLKSFTVFRQRGDAFADRLANAHVDAADG---YPVLQIG----------
MLBr_00961|M.leprae_Br4923 ARIDSIVASGTHRGDAAQRRTSQDARLHLP--PLPTTTIGSYPQTSAIRK
*: .: . : . * . . * :*
Mvan_0887|M.vanbaalenii_PYR-1 ---------MDTPQVSPELLERCAQSLLGSDAV-----------------
MSMEG_0996|M.smegmatis_MC2_155 ---------MDTPQVSAGLLSDCGQALLGADAV-----------------
MMAR_0886|M.marinum_M ---------MDTPQISAALLAECARRLLETSAV-----------------
MUL_0639|M.ulcerans_Agy99 ---------MDTPQISAALLAECARRLLETSAV-----------------
MAV_4604|M.avium_104 ---------MDTPQVTAELLAGCARRLLDAPAV-----------------
Mb0554|M.bovis_AF2122/97 ---------MDTPQVTAELLADCARLLLQIPAV-----------------
Rv0540|M.tuberculosis_H37Rv ---------MDTPQVTAELLADCARLLLQIPAV-----------------
MLBr_00961|M.leprae_Br4923 ARAALQDAEIDEAEYISRMKKEVADAIKLQEQLGLDVLVHGEPERNDMVQ
:* .: . : . : :
Mvan_0887|M.vanbaalenii_PYR-1 -----LG--LAGDGGWWVLG---------------------VRDAGFAEC
MSMEG_0996|M.smegmatis_MC2_155 -----LG--MACDGGWWVLG---------------------VHDAAAAAC
MMAR_0886|M.marinum_M -----LG--FAVDGGWWVLG---------------------VHTPAAAEC
MUL_0639|M.ulcerans_Agy99 -----LG--FAVDGGWWVLG---------------------VHTPAAAEC
MAV_4604|M.avium_104 -----LG--LARDGGWWVFG---------------------VAAPALADC
Mb0554|M.bovis_AF2122/97 -----LG--LAFDGGWWVLG---------------------IRTPTAAEC
Rv0540|M.tuberculosis_H37Rv -----LG--LAFDGGWWVLG---------------------IRTPTAAEC
MLBr_00961|M.leprae_Br4923 YFAEQLGGFFATQNGWVQSYGSRCVRPPILYGDVSRPHPMTIEWITYAQS
** :* :.** : * .
Mvan_0887|M.vanbaalenii_PYR-1 LRNVPMS--------------------TPDTGAVTLAALQDTDIHVE---
MSMEG_0996|M.smegmatis_MC2_155 LRTVPMS--------------------RPDTGELTLAALRDNGITVQ---
MMAR_0886|M.marinum_M LRGVPMS--------------------QPNTGELTLKALREGGIDVA---
MUL_0639|M.ulcerans_Agy99 LRGVPMS--------------------QPNTGELTLKALREGGFDVA---
MAV_4604|M.avium_104 LRAVPMS--------------------AADTGDLTLKALRDNGIEVA---
Mb0554|M.bovis_AF2122/97 LRAVPMS--------------------QPDTGELTLKALRDNGIDVT---
Rv0540|M.tuberculosis_H37Rv LRAVPMS--------------------QPDTGELTLKALRDNGIDVT---
MLBr_00961|M.leprae_Br4923 LTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAG
* *:. .:*. . *::: . :
Mvan_0887|M.vanbaalenii_PYR-1 LVCELVDVDTIDDVGAVRAG------CGPGSRFSRATAGVGP--------
MSMEG_0996|M.smegmatis_MC2_155 LLAELADVDTIDDIDPVRRA------CRPGSRFACATEGV----------
MMAR_0886|M.marinum_M TVQPLADVDVVADVAVVRGA------CGPDSRFARVTRLAGI--------
MUL_0639|M.ulcerans_Agy99 TVQPLADVDVVADVAVVRGA------CGPDSRFARVTRLAGI--------
MAV_4604|M.avium_104 TVQTLADVDVVGDVAVVRDA------CPPASRFARATRAAGL--------
Mb0554|M.bovis_AF2122/97 LVQRLGDFDIVDDIALVRDC------CAPGSRFAQATRAAGL--------
Rv0540|M.tuberculosis_H37Rv LVQRLGDFDIVDDIALVRDC------CAPGSRFAQATRAAGL--------
MLBr_00961|M.leprae_Br4923 IAIIQVDEPALRELLPLRRADQDEYLCWAVKAFRLATSGVADSTQIHTHL
* : :: :* * . . * .* .
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 CYSEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAVGFANSIGPGVYD
Mvan_0887|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0996|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0886|M.marinum_M --------------------------------------------------
MUL_0639|M.ulcerans_Agy99 --------------------------------------------------
MAV_4604|M.avium_104 --------------------------------------------------
Mb0554|M.bovis_AF2122/97 --------------------------------------------------
Rv0540|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00961|M.leprae_Br4923 IHSPRVPSTDEIAKSLRAALKAIPMQRLWVNPDCGLKTRSVDEVSASLQN
Mvan_0887|M.vanbaalenii_PYR-1 ------------
MSMEG_0996|M.smegmatis_MC2_155 ------------
MMAR_0886|M.marinum_M ------------
MUL_0639|M.ulcerans_Agy99 ------------
MAV_4604|M.avium_104 ------------
Mb0554|M.bovis_AF2122/97 ------------
Rv0540|M.tuberculosis_H37Rv ------------
MLBr_00961|M.leprae_Br4923 MVAAARQVRAGA