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QGHSDDQRELLDAESIAGHLLKSDSMFAFLAAHRHELFPEEMFADLFPSQRGRPSIPAEVMASVITLQAL HGLSDNETVDAVTFDLRWKAACGLPVTAGAFHSTTLTYWRRRLAASDRPNRIFEAVKAVVTATGVLAKKT RRALDSTVLDDAVATQDTVTQLIAAIRRVGREVSGAGEVIAAVCSAHDYTDAGKPAIAWNDKTARDQLVD GLVGDAHRLLGHLPEQDLGPRAAEAVALLALVAGQDVEPVEGSDGTDGHWQIAQKVAGDRVISTVDPEAR HAHKTVHRRQDGFKAHIAVEPDTGIITDCALTKASGPDNHEAVIGLALLADEHTPVRVLGDSAYGTGDAR AALAELKHVAVIKPLPLRVPVPGGFTSDDFIIDFDARTVTCPAEHTVAIGRTGGAGFEKHCRSCPLRQQC TTAKRGRKLTISEHEPHLRAARAVARTPEWQNEYRQHRPMVERSIAWLARGNRKVRYRGVTKNDHWLHHR VAALNLRRLITIGLIRNGTTWAIA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0747 | - | - | 100% (515) | transposase, IS4 family protein |
| M. vanbaalenii PYR-1 | Mvan_4071 | - | 0.0 | 100.00% (515) | transposase, IS4 family protein |
| M. vanbaalenii PYR-1 | Mvan_2074 | - | 0.0 | 100.00% (515) | transposase, IS4 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3418 | - | 1e-05 | 27.27% (132) | transposase |
| M. gilvum PYR-GCK | Mflv_2204 | - | 0.0 | 74.76% (515) | transposase, IS4 family protein |
| M. tuberculosis H37Rv | Rv3386 | - | 1e-05 | 27.27% (132) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1901 | - | 5e-05 | 26.98% (278) | DNA-binding HTH domain-containing protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0747|M.vanbaalenii_PYR-1 -MQGHSDDQRELLDAESIAGH---------------------LLKSDSMF
Mflv_2204|M.gilvum_PYR-GCK -MQGRSDDQREFLDAESVAGH---------------------LLKSDSVF
Mb3418|M.bovis_AF2122/97 -MFRTVGDQASLWES-VLPEE---------------------LRRLPEEL
Rv3386|M.tuberculosis_H37Rv -MFRTVGDQASLWES-VLPEE---------------------LRRLPEEL
MSMEG_1901|M.smegmatis_MC2_155 MLCGRDRELSELGEHVAAAEHTARLVVLTGEPGIGKTALLRDLTQRHGAW
: : .: : . . * :
Mvan_0747|M.vanbaalenii_PYR-1 AFLAAHRHELFPEEMFADLFPSQRGRPSIP--------------------
Mflv_2204|M.gilvum_PYR-GCK AFLAAYRRQLFPEEMFADLFPSRRGRPSVP--------------------
Mb3418|M.bovis_AF2122/97 ARVDALLDDSAFFCPFVPFFDPRMGRPSIP--------------------
Rv3386|M.tuberculosis_H37Rv ARVDALLDDSAFFCPFVPFFDPRMGRPSIP--------------------
MSMEG_1901|M.smegmatis_MC2_155 WALGASWETDLPGGVLAQLMQDDVPDDPLDGAAHLVDHVRAAGVRLLLVD
: * :. :: .:
Mvan_0747|M.vanbaalenii_PYR-1 AEVMASVITLQALHGLSDNE------------TVDAVTFDLRWKAACGLP
Mflv_2204|M.gilvum_PYR-GCK AEVMASVITLQALHGLSDNE------------TVDAVTFDLRWKAACGLP
Mb3418|M.bovis_AF2122/97 METYLRLMFLKFRYRLGYES------------LCREVTDSITWRRFCRIP
Rv3386|M.tuberculosis_H37Rv METYLRLMFLKFRYRLGYES------------LCREVTDSITWRRFCRIP
MSMEG_1901|M.smegmatis_MC2_155 DAHHADVESLQALSTLVRHQRDLPVLVVLATQSVDALPIPLAADDVVELT
: *: * .. :. : :.
Mvan_0747|M.vanbaalenii_PYR-1 ------------VTAGAFHSTTLTYWRRRLAAS---------DRPNRIFE
Mflv_2204|M.gilvum_PYR-GCK ------------ITAGAFHSTTLTYWRRRLAAS---------DRPNRIFE
Mb3418|M.bovis_AF2122/97 ------------LEGSVPHPTTLMKLTTRCGED---------AVAG--LN
Rv3386|M.tuberculosis_H37Rv ------------LEGSVPHPTTLMKLTTRCGED---------AVAG--LN
MSMEG_1901|M.smegmatis_MC2_155 GLPVAAVVELARLRGITIHPTLADRLTRHAGGNPRDVLALFDEVPASAWA
: . . *.* : . . .
Mvan_0747|M.vanbaalenii_PYR-1 AVKAVVTATGVLAKKTRRALDST-----------VLDDAVATQDTVTQLI
Mflv_2204|M.gilvum_PYR-GCK AVKTVVAATGALTGKTRRALDST-----------ILDDAVATQDTVTQLI
Mb3418|M.bovis_AF2122/97 EALLAKAASEKLLRTNKVRADTT-----------VVEGDVGYP-------
Rv3386|M.tuberculosis_H37Rv EALLAKAASEKLLRTNKVRADTT-----------VVEGDVGYP-------
MSMEG_1901|M.smegmatis_MC2_155 RLDSSLPAPRHVVERVATQLDSCGPAGRALVQALAVLGAAGGGDATDATD
.*. : *: : . ..
Mvan_0747|M.vanbaalenii_PYR-1 AAIRRVGREVSGAGEVIAAVCSAHDYTDAGKPAIAWNDKTARDQLVDGLV
Mflv_2204|M.gilvum_PYR-GCK GAIRRVRREVPGAGEVVASQCSAHDYDDPGKPAITWDDAAAREMLVNALV
Mb3418|M.bovis_AF2122/97 --------------------------TDTG--------------LLAKAV
Rv3386|M.tuberculosis_H37Rv --------------------------TDTG--------------LLAKAV
MSMEG_1901|M.smegmatis_MC2_155 TVTLAEAADLAGLSGPSEPLAALDEAVDAG---LVTHVVHFEPRLTDGLT
*.* * .
Mvan_0747|M.vanbaalenii_PYR-1 G-DAHRLLGHLPEQDLGPRAAEAVA--------------LLALVAGQDVE
Mflv_2204|M.gilvum_PYR-GCK T-DAHRLLGHLPDQELGVRAAEAVA--------------LLALIAGQDVE
Mb3418|M.bovis_AF2122/97 G-SMARTVARIKAADAGS-------------------------------A
Rv3386|M.tuberculosis_H37Rv G-SMARTVARIKAADAGS-------------------------------A
MSMEG_1901|M.smegmatis_MC2_155 GPAVLTLLGARATAEAHRRAAEVITDPRRRLRHRVAAAAAPDEALAGEVD
:. :
Mvan_0747|M.vanbaalenii_PYR-1 PVEGSDGTDGHWQIAQKVAGDRVISTVDPEA--RHAHKTVHRRQDGFKAH
Mflv_2204|M.gilvum_PYR-GCK PVDDSDGTDGRWRIAQRVAQDRVISTVDPDA--RHAHKSVHRRQDGFKAH
Mb3418|M.bovis_AF2122/97 PLGGSSGPR------------------------DRLQAAVTRR-------
Rv3386|M.tuberculosis_H37Rv PLGGSSGPR------------------------DRLQAAVTRR-------
MSMEG_1901|M.smegmatis_MC2_155 ALARASGADGAWALAATLFHDASRLTSDPLLRDERLTRSVDALVAAGDCG
.: :.*. : :*
Mvan_0747|M.vanbaalenii_PYR-1 IAVEPDTGIITDCALTKASGPDNHEAVIGLALLADEHTPVRVLGDSAYGT
Mflv_2204|M.gilvum_PYR-GCK IAVEPDTGLITDCALTKAGGAGTHDAAVAPQLLAGESAPVTVLADSAYGS
Mb3418|M.bovis_AF2122/97 -------------AATRSG-------------------------------
Rv3386|M.tuberculosis_H37Rv -------------AATRSG-------------------------------
MSMEG_1901|M.smegmatis_MC2_155 AAAQLIPVVESLRETPLRNAVLAYLAILRGRATEAEVRLRRAWDIVNAER
. .
Mvan_0747|M.vanbaalenii_PYR-1 GDARAALAELKHVAVIKPLPLRVPVPGGFTSDDFIIDFDARTVTCPAEHT
Mflv_2204|M.gilvum_PYR-GCK GDFRAQLRKSRHRDRVKPAPLRAAVPGGFTIDDFTVDHRGHRVTCPAGVA
Mb3418|M.bovis_AF2122/97 ----AGLRAPDHRG------------------------------------
Rv3386|M.tuberculosis_H37Rv ----AGLRAPDHRG------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 DPETAALIAQRYVLHSLVRGRGTELVRWADTALRLADRESPTAVESAAVR
* * :
Mvan_0747|M.vanbaalenii_PYR-1 VAIGRTGGAGFEKHCRSCPLRQQCTTAKRGRKLTIS--------------
Mflv_2204|M.gilvum_PYR-GCK RSISARGNATFGAACRGCALRPQCTTSIDGRSLKIG--------------
Mb3418|M.bovis_AF2122/97 --ASRDRRAGADRGCRGGT-------------------------------
Rv3386|M.tuberculosis_H37Rv --ASRDRRAGADRGCRGGT-------------------------------
MSMEG_1901|M.smegmatis_MC2_155 GLGLAAAGRAEQATAAYDELAERITHGAQAQRVTLGRGWLQLIRDDVDGA
.
Mvan_0747|M.vanbaalenii_PYR-1 --------EHEPHLRAARAVARTPEWQNEYRQHRPMVERSIAWLARGNRK
Mflv_2204|M.gilvum_PYR-GCK --------PHDALQRAARKRSQKPRWLNEYRQHRPMVERTIAWLTRGNRK
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 RSNLESAIATANLGGSSRITLWAMAWLARAHFVSGDWDAALATVVSGRDL
Mvan_0747|M.vanbaalenii_PYR-1 VRYRGVTKNDHWLHHRVAALNLRR---------------------LITIG
Mflv_2204|M.gilvum_PYR-GCK VRYRGVTRNDQWLHHRAAAVNLHR---------------------LITLG
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 AASSGITITTPLLEWIAAQISALRGDWETAHAAVQAADRVTQDYEMMRIP
Mvan_0747|M.vanbaalenii_PYR-1 LIRNGTTWAIA---------------------------------------
Mflv_2204|M.gilvum_PYR-GCK LTHTGAGWAIA---------------------------------------
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 TILARAQVAEAEADYPKVRRVLEPLAALAARAPGTVLTEPGYWPWPDVLA
Mvan_0747|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2204|M.gilvum_PYR-GCK --------------------------------------------------
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 NALVIDGALDEADEFLRPHEEVARERGHRSAMARLGYARGRLLGARGELS
Mvan_0747|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2204|M.gilvum_PYR-GCK --------------------------------------------------
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 AARARFEESLALLDGLPLRYDRARVNFAYGQTLRRAGKRRDADAVIATAR
Mvan_0747|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2204|M.gilvum_PYR-GCK --------------------------------------------------
Mb3418|M.bovis_AF2122/97 --------------------------------------------------
Rv3386|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 DLYLSLGAHTYVARCDRELKAGGLHQLRGSRDSVELTPQEDAVTALVAQG
Mvan_0747|M.vanbaalenii_PYR-1 -----------------------------------------
Mflv_2204|M.gilvum_PYR-GCK -----------------------------------------
Mb3418|M.bovis_AF2122/97 -----------------------------------------
Rv3386|M.tuberculosis_H37Rv -----------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 LSNREVAAELYVSPKTVQYHLTRVYAKLGVRSRAELAALRR