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VLELKTPQEIAAMDVTGTFIAELLDDLAGRARPGVNLLDLELRARTLLAERGAQSCYWDYAPSFGRGPFR NVICLSVNDAVLHGLPHDYVLADGDLLSMDIAVSIDGWVADSARSIIVGTPRAEDRRLIAATEEALAAGI AAALPGNRLGDISAAIGAVAADYGYPVNTEFGGHGLGRTMHEDPHVSNVGRAGRGLKLRQGLTLALEPWF AAGTDKIVYDPDGWTIRSADGSRTAHSEHTIAITDGPALVLTRRERVTAAPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0391 | - | - | 100% (262) | methionine aminopeptidase, type I |
| M. vanbaalenii PYR-1 | Mvan_1349 | - | 1e-46 | 42.69% (260) | methionine aminopeptidase |
| M. vanbaalenii PYR-1 | Mvan_2272 | - | 3e-32 | 31.87% (251) | methionine aminopeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0755 | mapA | 2e-45 | 42.31% (260) | methionine aminopeptidase |
| M. gilvum PYR-GCK | Mflv_0784 | - | 1e-102 | 71.83% (252) | methionine aminopeptidase, type I |
| M. tuberculosis H37Rv | Rv0734 | mapA | 2e-45 | 42.31% (260) | methionine aminopeptidase |
| M. leprae Br4923 | MLBr_01831 | mapA | 4e-44 | 40.38% (260) | methionine aminopeptidase |
| M. abscessus ATCC 19977 | MAB_0094c | - | 1e-106 | 73.81% (252) | methionine aminopeptidase, type I (MAP) |
| M. marinum M | MMAR_1072 | mapA | 6e-43 | 41.15% (260) | methionine aminopeptidase, MapA |
| M. avium 104 | MAV_4432 | map | 2e-45 | 42.31% (260) | methionine aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_5050 | map | 1e-109 | 75.89% (253) | methionine aminopeptidase, type I |
| M. thermoresistible (build 8) | TH_3403 | - | 5e-44 | 41.31% (259) | PUTATIVE methionine aminopeptidase, type I |
| M. ulcerans Agy99 | MUL_0830 | mapA | 4e-43 | 41.15% (260) | methionine aminopeptidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0755|M.bovis_AF2122/97 MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLS
Rv0734|M.tuberculosis_H37Rv MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLS
MAV_4432|M.avium_104 MNALARLRGRKVVPQRSDGELDAMAAAGAVVAAALQAVRAAAVAGVSTLS
MMAR_1072|M.marinum_M MRALARLRGRKVVPQRTAGELDAMAAAGAVVAAAHQAVRSAAVAGVSTLQ
MUL_0830|M.ulcerans_Agy99 MRALARLRGSRVVPQRTAGELDAMAAAGAVVAAAHQAVRSAAVAGVSTLQ
MLBr_01831|M.leprae_Br4923 MGALTRLRSRRVVPQRSVGELDAMAAAGAVVAAALHAVRDAAGPGVSSLS
TH_3403|M.thermoresistible__bu -LVGLRLRNRKVVAQRSAGELDAMAAAGALVAEALRAVQAAAAPGVSTKH
Mvan_0391|M.vanbaalenii_PYR-1 -----------MLELKTPQEIAAMDVTGTFIAELLDDLAGRARPGVNLLD
MSMEG_5050|M.smegmatis_MC2_155 -----------MIELKTPAEIDKMRTTGRFVAEVLRELSEMAAVGVNLLD
Mflv_0784|M.gilvum_PYR-GCK -----------MIELKTAREIDRMAVTGEFVAQTLADLSRHAEPGVNVLD
MAB_0094c|M.abscessus_ATCC_199 -----------MIELKSPAEIGRMRVTGEFVASVLAELSSLAAPGVNLLD
:: :: *: * .:* .:* : * *..
Mb0755|M.bovis_AF2122/97 LDEIAESVIRESGATPSFLGYHG------YPASICASINDRVVHGIPSTA
Rv0734|M.tuberculosis_H37Rv LDEIAESVIRESGATPSFLGYHG------YPASICASINDRVVHGIPSTA
MAV_4432|M.avium_104 LDQIAESVIRDAGAVPSFLGYHG------YPASICASVNDRVVHGIPSGA
MMAR_1072|M.marinum_M LDEIAESVIREAGATPSFLGYHG------FPASICASVNDRVVHGIPSAT
MUL_0830|M.ulcerans_Agy99 LDEIAESVIREAGATPSFLGYHG------FPASICASVNDRVVHGIPSAT
MLBr_01831|M.leprae_Br4923 LDEIAESVIREAGATPSFLRYHG------YPATICTSVNDRVIHGIPSAV
TH_3403|M.thermoresistible__bu LDEIAESVIRDGGGIPSFLGYHG------FPASICASVNERVVHGIPADD
Mvan_0391|M.vanbaalenii_PYR-1 LELRARTLLAERGAQSCYWDYAPSFGRGPFRNVICLSVNDAVLHGLP-HD
MSMEG_5050|M.smegmatis_MC2_155 LEHRARDMIAERGATSCYWDYHPSFGSGPFRNVICLSVNDAVLHGLP-HS
Mflv_0784|M.gilvum_PYR-GCK LEHRARRLVADRGAVSCYWDYAPSFGRGPFRNVICLSVNDAVLHGLP-HD
MAB_0094c|M.abscessus_ATCC_199 LEQRAREMVSDRGAVSCYWDYSPSFGRGPFRNVICLSVNDAVLHGLP-HD
*: *. :: : *. ..: * : ** *:*: *:**:*
Mb0755|M.bovis_AF2122/97 EVLAPGDLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRESLQA
Rv0734|M.tuberculosis_H37Rv EVLAPGDLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRESLQA
MAV_4432|M.avium_104 EVLAPGDLVSMDCGAVLDGWHGDAAITFGVGALDPADEALRQATRESLEA
MMAR_1072|M.marinum_M EILGPGDLVSIDCGAVLDGWHGDAAITFGIGTLIPVDEALSEATRESLEA
MUL_0830|M.ulcerans_Agy99 EILGPGDLVSIDCGAVLDGWHGDAAITFGIGTLIPVDEALSEATRESLEA
MLBr_01831|M.leprae_Br4923 EILAPGDLVSIDCGAVLDGWHGDAAITFGVGTLTSVDEALSQATRESLEA
TH_3403|M.thermoresistible__bu EILAAGDLVSIDCGAILDGWHGDSAITFGVGDLIPADEALSQATKAALDA
Mvan_0391|M.vanbaalenii_PYR-1 YVLADGDLLSMDIAVSIDGWVADSARSIIVGTPRAEDRRLIAATEEALAA
MSMEG_5050|M.smegmatis_MC2_155 YVLRDGDVLSLDFAVSIDGWVADAARTVIVGTPDAEDERLVQATRDALAA
Mflv_0784|M.gilvum_PYR-GCK HVLRDGDLLSMDFAVSIDGWVADAAVTLIVGDGAAEDRALIDSTRRALDA
MAB_0094c|M.abscessus_ATCC_199 YVLADGDLLSMDFAVSIDGWVADSAVSVIVGTPEPEDVRLIDTTRAALDA
:* **::*:* .. :*** .*:* :. :* * * :*. :* *
Mb0755|M.bovis_AF2122/97 GIAAMVVGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHM
Rv0734|M.tuberculosis_H37Rv GIAAMVVGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHM
MAV_4432|M.avium_104 GIAAMVPGNRLTDVSHAIELGTRAAETRHGRAFGIVEGYGGHGIGRQMHM
MMAR_1072|M.marinum_M GIAAMVIGNRLTDVAHAIETETRAAEARYQRSFGIVDGYGGHGIGREMHM
MUL_0830|M.ulcerans_Agy99 GIAAMVIGNRLTDVAHAIETETRAAEARYQRSFGIVDGYGGHGIGREMHM
MLBr_01831|M.leprae_Br4923 GIAAMIVNNRLTDVAHAIEVSTRTSEIRYRLTFGIVQGYGGHGIGRHMHM
TH_3403|M.thermoresistible__bu GIDAMRPGNRLTDVSHAIETATRAAERRDNRRYGIVANYGGHGIGRQMHM
Mvan_0391|M.vanbaalenii_PYR-1 GIAAALPGNRLGDISAAIGAVAADYG------YPVNTEFGGHGLGRTMHE
MSMEG_5050|M.smegmatis_MC2_155 ATAAAVPGNRLGDISAAIGAVADDYG------YPVNLEFGGHGLGRTMHE
Mflv_0784|M.gilvum_PYR-GCK GIAAATPGARLGDISAAIGAVAGAGG------YAVNTDFGGHGLGRTMHE
MAB_0094c|M.abscessus_ATCC_199 AIGAALPGNRLGDISAAVAAVAEGAG------YRINTDFGGHGLGRTMHE
. * . ** *:: *: : : : :****:** **
Mb0755|M.bovis_AF2122/97 DPFLPNEGAPGRGPLLAAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGS
Rv0734|M.tuberculosis_H37Rv DPFLPNEGAPGRGPLLAAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGS
MAV_4432|M.avium_104 DPFLPNEGSPGRGPLLAPGSVLAIEPMLTLGTGKTVVLDDQWTVITTDGS
MMAR_1072|M.marinum_M DPFLPNEGAPGRGPTLVAGSVLAIEPMLTLGTRKTVVLDDQWTVITADGS
MUL_0830|M.ulcerans_Agy99 DPFLPNEGAPGRGPTLVAGSVLAIEPMLTLGTRKTVVLDDQWTVITADGS
MLBr_01831|M.leprae_Br4923 DPFLPNEGAPGRGPLLVPGSVLAIEPMLTLGTGKTIVLDDEWTVTTADGS
TH_3403|M.thermoresistible__bu DPFLPNEGAPGRGPHLAVGSVLAIEPMLTLGTTETVVLADEWTVVTADGS
Mvan_0391|M.vanbaalenii_PYR-1 DPHVSNVGRAGRGLKLRQGLTLALEPWFAAGTDKIVYDPDGWTIRSADGS
MSMEG_5050|M.smegmatis_MC2_155 DPHVPNRGRPGRGMRLRDGMTLALEPWFARTTDRIRFDRDGWTIRSADGS
Mflv_0784|M.gilvum_PYR-GCK DPHVPNRGKPGRGLVLQPGMALALEPWWGRGTARLIVDDDGWTLRSADGS
MAB_0094c|M.abscessus_ATCC_199 DPHVPNKGTAGRGMKLEPGLTLALEPWFGRGTDRLTVDADGWTLRMADGS
**.:.* * .*** * * .**:** * . * **: :***
Mb0755|M.bovis_AF2122/97 RAAHWEHTVAVTDDGPRILTLG--------
Rv0734|M.tuberculosis_H37Rv RAAHWEHTVAVTDDGPRILTLG--------
MAV_4432|M.avium_104 RAAHWEHTVAVTDAGPRILTLG--------
MMAR_1072|M.marinum_M RAAHWEHTVAVTENGPRILTLG--------
MUL_0830|M.ulcerans_Agy99 RAAHWEHTVAVTENGPRILTLG--------
MLBr_01831|M.leprae_Br4923 RAAHWEHTVAVTEDGPRVLTLA--------
TH_3403|M.thermoresistible__bu RAAHWEHTVAVTEDGPRILTL---------
Mvan_0391|M.vanbaalenii_PYR-1 RTAHSEHTIAITDGPALVLTRRERVTAAPR
MSMEG_5050|M.smegmatis_MC2_155 RTAHTENTVAITADGPLVLTAD--------
Mflv_0784|M.gilvum_PYR-GCK NTAHSEHTIAVTEHGPRVLTALG-------
MAB_0094c|M.abscessus_ATCC_199 RGAHSEHTIAITEDGPQVLTVQG-------
. ** *:*:*:* . :**