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MTTAFRDLLGPQRLTDVVDIGANPIDGEPPYSPMLTEGLCRVTGFEPQPEALHDLQSRKGPYERYLPYAV GDGSEHTLNICRGSGMTSLFEPDPATLGLFEILGPYAEVVDRVALPTQRLDEVAEIEHLDFLKIDIQGGE LAVFCNGREKLADAVVIQTEVSFVTLYKDQPAMGAIDVELRSQGFIPHCFAAVKHWPIAPYVVEGNPRQA VNQLLEADIVYVRDFSRPDSLSDEQLKHLALIAHHCYGSVDLALRCVMLLEDRGSIEVGARQRYSEILTA S
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5092 | - | - | 100% (281) | FkbM family methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2980 | - | 2e-06 | 29.76% (168) | hypothetical protein Mb2980 |
| M. tuberculosis H37Rv | Rv2956 | - | 2e-06 | 29.76% (168) | hypothetical protein Rv2956 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4509 | - | 1e-97 | 59.86% (279) | hypothetical protein MMAR_4509 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4680 | - | 3e-97 | 59.86% (279) | hypothetical protein MUL_4680 |
| M. vanbaalenii PYR-1 | Mvan_1263 | - | 1e-133 | 81.52% (276) | FkbM family methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5092|M.gilvum_PYR-GCK --------------------------MTTAFRDLLGPQRLTDVVDIGANP
Mvan_1263|M.vanbaalenii_PYR-1 --------------------------MITAFRDLLAPSRLTDVVDVGANP
MMAR_4509|M.marinum_M --------------------------MTGGLRDILSPSRLTHIVDVGASR
MUL_4680|M.ulcerans_Agy99 --------------------------MTGGLRDILSPSRLTHIVDVGASR
Mb2980|M.bovis_AF2122/97 MKSLKLARFIARSAAFEVSRRYSERDLKHQFVKQLKSRRVDVVFDVGAN-
Rv2956|M.tuberculosis_H37Rv MKSLKLARFIARSAAFEVSRRYSERDLKHQFVKQLKSRRVDVVFDVGAN-
: : . * . *: :.*:**.
Mflv_5092|M.gilvum_PYR-GCK IDGEPPYSPMLTEGLCRVTGFEPQ--PEALHDLQSRKGPYERYLPYAVGD
Mvan_1263|M.vanbaalenii_PYR-1 IDGEPPYAPMLSAGLCRVTGFEPQ--PDALAELQTRKGPGERYLPYAVGD
MMAR_4509|M.marinum_M SCGDWPYTAMLNAGLCHLTGFEPG--PEALLELQRTRGPNESYLPYALGD
MUL_4680|M.ulcerans_Agy99 SCGDWPYTAMLNAGLCHLTGFEPG--PEALLELQRTRGPNESYLPYALGD
Mb2980|M.bovis_AF2122/97 -SGQYAAGLRRAAYKGRIVSFEPLSGPFTILESKASTDPLWDCRQHALGD
Rv2956|M.tuberculosis_H37Rv -SGQYAAGLRRAAYKGRIVSFEPLSGPFTILESKASTDPLWDCRQHALGD
*: . ::..*** * :: : : .* :*:**
Mflv_5092|M.gilvum_PYR-GCK G-SEHTLNICRGSG-MTSLFEPDPATLGLFEILGPYAEVVDRVALPTQRL
Mvan_1263|M.vanbaalenii_PYR-1 G-GEHTLNICRASG-MTSLFEPDPDTLNLFEVLEPYGEVLERIPLSTHRL
MMAR_4509|M.marinum_M G-TPQTLQVCPPPGGMTSLLEPDPTTQGLFTLFDPFGKVIERLPIQTHRL
MUL_4680|M.ulcerans_Agy99 G-TPQTLQVCPPPGGMTSLLEPDPTTQGLFTLFDPFGKVIERLPIQTHRL
Mb2980|M.bovis_AF2122/97 SDGTVTINIAGNAGQSSSVLPMLKSHQNAFPPANYVGTQEASIHRLDSVA
Rv2956|M.tuberculosis_H37Rv SDGTVTINIAGNAGQSSSVLPMLKSHQNAFPPANYVGTQEASIHRLDSVA
. *:::. .* :*:: . * . :
Mflv_5092|M.gilvum_PYR-GCK DEVAEIEHLDFLKIDIQGGELAVFCNGREKLADAVV-IQTEVSFVTLYKD
Mvan_1263|M.vanbaalenii_PYR-1 DDISEIEHLDFLKIDIQGGELAVFQNGRTKLADAVA-IQTEVSFVTLYRD
MMAR_4509|M.marinum_M DDIGEIEHLDLLKIDIQGGELAVFQNGREKLAEAVA-VQTEVSFITLYRD
MUL_4680|M.ulcerans_Agy99 DDIGEIEHLDLLKIDIQGGKLAVFQNGREKLAEAVA-VQTEVSFITLYRD
Mb2980|M.bovis_AF2122/97 PEFLGMNGVAFLKVDVQGFEKQVLAGGKSTIDDHCVGMQLELSFLPLYEG
Rv2956|M.tuberculosis_H37Rv PEFLGMNGVAFLKVDVQGFEKQVLAGGKSTIDDHCVGMQLELSFLPLYEG
:. :: : :**:*:** : *: .*: .: : . :* *:**:.**..
Mflv_5092|M.gilvum_PYR-GCK QPAMGAIDVELRSQGFIPHCFA-AVKHWPIAPYVVEGNPRQAVNQLLEAD
Mvan_1263|M.vanbaalenii_PYR-1 QPTMGDVDVEMRSQGFVPHCFA-AVKKWPIAPYVVNNNPRWALNQLLEAD
MMAR_4509|M.marinum_M QPSFGDVDLELRSQGFVPHCIPNAVKRWVIGDFVVGGSPSRPLNQILETD
MUL_4680|M.ulcerans_Agy99 QPRFGDVDLELRSQGFVPHCIPNAVKRWVIGDFVVGGSPSRPLNQILETD
Mb2980|M.bovis_AF2122/97 GMLIPEALDLVYSLGFT--------LTGLLPCFIDANN-----GRMLQAD
Rv2956|M.tuberculosis_H37Rv GMLIPEALDLVYSLGFT--------LTGLLPCFIDANN-----GRMLQAD
: : * ** : :: .. .::*::*
Mflv_5092|M.gilvum_PYR-GCK IVYVRDFSRPDSLSDEQLKHLALIAHHCYGSVDLALRCVMLLEDRGSIEV
Mvan_1263|M.vanbaalenii_PYR-1 IVYVRDFSRPDSLSDEQLKHLALIAHHCYSSYDLALRCVMLLERRGSLKT
MMAR_4509|M.marinum_M IVYVRNFFDPDAMTAEQLKHLAMISHHCYGSFDLAFRCVQLLQARGAVGT
MUL_4680|M.ulcerans_Agy99 IVYVRDFFDPDAMTAEQLKHLAMISHHCYGSFDLAFRCVQLLQARGAVGP
Mb2980|M.bovis_AF2122/97 GTFFREDD------------------------------------------
Rv2956|M.tuberculosis_H37Rv GIFFREDD------------------------------------------
:.*:
Mflv_5092|M.gilvum_PYR-GCK GARQRYSEILTAS------------------------------------
Mvan_1263|M.vanbaalenii_PYR-1 GAQQSYLETRPA-------------------------------------
MMAR_4509|M.marinum_M ASAQRYLDIYRRAVRHKSALWRAQNGATRLKHRLRASAAKWTRSPGRGR
MUL_4680|M.ulcerans_Agy99 PSAQRYLDIYRRAVRHKSALWRAQNAASRLKHRLRASAAKWTRSPGRGR
Mb2980|M.bovis_AF2122/97 -------------------------------------------------
Rv2956|M.tuberculosis_H37Rv -------------------------------------------------