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MPRFKRPIDPVRWQAPPVDPLPEFGSAALTLTPIPGGEPEDVVVDARGYLWTGALDGSIVRLRPDGTAPE VVANTGGRPLGLAFARDGRLLVCDSPRGLLALDVDTGAIETLVTSIDGRPLLFCSNVTETSDGTVYFTES TSAFTIDQYLGAILEARGRGALHRLDPDGRVTTVVDGLYFANGVTPTADGSALVFAETQGRRLSKYWLTG PNAGSVTPLAVNLPAMPDNLSTGAEGRIWCAMVTPANPVADRLAAGPPVLRKLVWRLPARLQPKPEAVAW AVAFDPDSGDAVAGFRTTHPEFRMATGLVESGGRLWLGSIGGPYLASVDLAATAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4863 | - | - | 100% (335) | strictosidine synthase |
| M. gilvum PYR-GCK | Mflv_4109 | - | 2e-14 | 30.20% (202) | SMP-30/gluconolaconase/LRE domain-containing protein |
| M. gilvum PYR-GCK | Mflv_1786 | - | 3e-06 | 28.92% (166) | SMP-30/gluconolaconase/LRE domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3680 | - | 4e-93 | 50.88% (340) | strictosidine synthase family protein |
| M. marinum M | MMAR_0391 | - | 4e-12 | 28.83% (222) | hypothetical protein MMAR_0391 |
| M. avium 104 | MAV_5132 | - | 1e-16 | 32.13% (221) | senescence marker protein-30 (SMP-30) |
| M. smegmatis MC2 155 | MSMEG_2561 | - | 7e-13 | 29.82% (228) | gluconolactonase |
| M. thermoresistible (build 8) | TH_3744 | - | 3e-13 | 32.64% (239) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1568 | - | 1e-162 | 81.90% (326) | strictosidine synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4863|M.gilvum_PYR-GCK MPRFKRPIDPVRWQAPPVDPLPEFG--SAALTLTPIPGGEPEDVVVDARG
Mvan_1568|M.vanbaalenii_PYR-1 ---MKPSIDPVRWHAPPVQDLPEFG--AAELTLVPVPGGEPEDVVVDAEG
MAB_3680|M.abscessus_ATCC_1997 --MAKPSIDPVRWQPPGVRALSLEPQPLPRLSIVALPGHGPEDVVADAAG
MMAR_0391|M.marinum_M ------------MHDTFAVICNGTRREVSPLARGFCFGEGPR----WFEG
MAV_5132|M.avium_104 ------------------MIP-------EPLVNGFCFGEGPR----WFEG
MSMEG_2561|M.smegmatis_MC2_155 ------------------MTTEAGPERTTELATGFCFGEGPR----WFEG
TH_3744|M.thermoresistible__bu ---LAFPESPIAEADGSVLVSEIAG---GCITRVRPDGTTEKVADTGGGP
: * .
Mflv_4863|M.gilvum_PYR-GCK YLWTGALDGSIVRLRPD---GTAPEVVANTGGRPLGLAFARDGRLLVCDS
Mvan_1568|M.vanbaalenii_PYR-1 NLWTGALDGGIVRLRPD---GSSPELIANTGGRPLGLTFARDGRLLVCDS
MAB_3680|M.abscessus_ATCC_1997 NIWAGVADGRIFRISPDDTEGAAVTHVATTEHPPLGLHIARDGRVLICSR
MMAR_0391|M.marinum_M LLWFSDMLGEAVHTSDM---HGSLTTLPLPGHSPCGLGFRPDGTLLIASA
MAV_5132|M.avium_104 LLWFSDMLGEAVHTTTM---GGALTTLPLPGHCPSGLGFRPDGSLLIAST
MSMEG_2561|M.smegmatis_MC2_155 LLWFSDMLGEAVHTVTL---GGSMTTLPLPGHAPSGLGFRPDGTLYIVST
TH_3744|M.thermoresistible__bu NGIARLPDGRLVVCQNG---GSTFGVGSWPYDLPGATKLFRPIGPATAPL
* . : . . * . :
Mflv_4863|M.gilvum_PYR-GCK PRGLLALDVDT----GAIETLVTSIDGRPLLFCSNVTETSDGTVYFTEST
Mvan_1568|M.vanbaalenii_PYR-1 PRGLLAVDTTT----GTVETLVHSVGGRPLIFCSNVTETADGTVYFTEST
MAB_3680|M.abscessus_ATCC_1997 DK-LLALDPAS----GKIEPVVTKVDGPPLIFCSNVTESMDGTIYFSEST
MMAR_0391|M.marinum_M HD-RLVLRYDG----DTVVTVADLRDLAPADLGDMVIDRAG---------
MAV_5132|M.avium_104 RD-RRVLRYDG----ETVVTVAELADIAPADLGDMVVDRAG---------
MSMEG_2561|M.smegmatis_MC2_155 EK-RQVLCYDG----ETVELLADLHQVAPAPLGDMVLDERG---------
TH_3744|M.thermoresistible__bu TPQLQVIDADGRIETLTTEFIARNGQRLPLVRPSDVCVDSSGGYYVTDG-
.: :. * . * .
Mflv_4863|M.gilvum_PYR-GCK SAFTIDQYLGAILEARGRGALHRLDPDG---RVTTVVDGLYFANGVTPTA
Mvan_1568|M.vanbaalenii_PYR-1 TAFTVGNYLGAILEARGRGALHRLEPHG---RLTTVVDGLYFANGVTPTA
MAB_3680|M.abscessus_ATCC_1997 ARFPFEQFMAAILEGRPTGRVFRRDPDG---TVTTIATGLAFTNGVTITA
MMAR_0391|M.marinum_M -----RAYIG--CQSFSGGVIIRLDTDN---SAQVVAEDLDFPNGMVITP
MAV_5132|M.avium_104 -----RAYIG--CQAFTRGAIIRLDPDD---RAKVVADDLDFPNGMAITP
MSMEG_2561|M.smegmatis_MC2_155 -----RAYVG--SQARGGGVIVRIDPDDPVEPIRVVAEGLDFPNGMAITP
TH_3744|M.thermoresistible__bu -----GTIRG---RSREMTGLLYAGLDG---VLREIVYPLEMPNGVALSP
. .. : .. :. * :.**:. :.
Mflv_4863|M.gilvum_PYR-GCK DGSALVFAETQGRRLSKYWLTG-PNAGSVTPLAVNLPAMPDNLSTGAEGR
Mvan_1568|M.vanbaalenii_PYR-1 DGSALVFAETQGRRLSKYWLTG-PDAGNVTPLAVNLPAMPDNLSTGADGR
MAB_3680|M.abscessus_ATCC_1997 DGSALIIAETVGRRVSRYALTG-PAAGTLTPIVEEIPGMPDNISTGADGR
MMAR_0391|M.marinum_M DHDTLIVAESVGRRLSAFTVSADGALNDRRVFAAGLDGPPDGIALDAEGA
MAV_5132|M.avium_104 DGATLIVAESTGRRLSAFAIDDDGALSGRRVFADGLDGPPDGIALDADGG
MSMEG_2561|M.smegmatis_MC2_155 DGETLIVAESTARRLTAYTVDEDGDLSDRRIFAEGLDGPPDGIAIDLEGG
TH_3744|M.thermoresistible__bu DESKLYVAETRTRRIWEFGLDEPGVIGS----ARGLATVPSGGPLNVGGA
* * .**: **: : : . . : *.. . . *
Mflv_4863|M.gilvum_PYR-GCK IWCAMVTPANPVADRLAAGPPVLRKLVWRLPARLQPKPEAVAWAVAFDPD
Mvan_1568|M.vanbaalenii_PYR-1 IWCAMVTPANPLADRLAAGPPLLRKLVWRLPSRVQPKPEAVVWVVAFDPD
MAB_3680|M.abscessus_ATCC_1997 IWITLASPRNALAEWLLPRSPAIRKVLWRLPDALLPGTDTDPWVIAVNPD
MMAR_0391|M.marinum_M VWAAMT-LAHQFERIVAGG---------VVTDRIDMG-DRVAIACALGGP
MAV_5132|M.avium_104 VWAAMT-LAHQFERIVAGG---------AVTDRIDIG-DRVAIACALGGP
MSMEG_2561|M.smegmatis_MC2_155 VWTALT-LAHEFQRIVDSGPGTP-----TVTDRIDAG-GRTAIACALGGA
TH_3744|M.thermoresistible__bu DGLCVDSAGRILVATLGTG-------------GVTVFSAAGELLGAIEAD
: . . : : *.
Mflv_4863|M.gilvum_PYR-GCK SGDAVAGFRTTHPEFRMATGLVESGGRLWLGSIGGPYLASVDLAATAP--
Mvan_1568|M.vanbaalenii_PYR-1 TGAAVAGMRTTHPDFSMVTGVAEAGGRLWMGSIGSPNLGWITL-------
MAB_3680|M.abscessus_ATCC_1997 TGDVLANITGKSRDLRTVTGVVESGGRLWMGCIGSSAVGHISLADIASSS
MMAR_0391|M.marinum_M GRRTLFLLSSTDAYPKRLIGTRLS--QLDAVTVATPGAG-LP--------
MAV_5132|M.avium_104 QRRTLFLLSSTDAYPQRLVGTRLS--RLDAVTVTTPGAG-LP--------
MSMEG_2561|M.smegmatis_MC2_155 EGRTLFLVTTTDAYPQRLVGTKLS--RIEALDVAVPAPGDFAVGDHHHH-
TH_3744|M.thermoresistible__bu DP--MTTNMTLSPDETRLYVTLASSGRILVVEDWMTAAGIR---------
: : :: . .
Mflv_4863|M.gilvum_PYR-GCK ---
Mvan_1568|M.vanbaalenii_PYR-1 ---
MAB_3680|M.abscessus_ATCC_1997 SGP
MMAR_0391|M.marinum_M ---
MAV_5132|M.avium_104 ---
MSMEG_2561|M.smegmatis_MC2_155 ---
TH_3744|M.thermoresistible__bu ---