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SEVIQPRRVSAVIRAYNEGKHIGRLLKGLEQQTVRVDEIILVDSGSTDDTVAIAEAAGCKIVAIAKSEFS FGRALNRGCAAASGDILLFASAHVYPVYDTYVEHIVNAFDRQGVAIAYGRQVGDERTKFSESRVMLKWFP TENIWDQGHPFSNNANAAVLRSVWEESPYDEGLTGLEDLDFAQKALAAGHKIAYVADAPVVHVHEESWEI TRNRYRREAIAYAHIVEGSEMSLSRAVGLALSNIVGDYIDAAKAKRIRGNLLSIPLFRSAQFLGAWEGFR APANVSARLLERFYYPADSQSYDLPPAPGRRILYSDDMSISHQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4770 | - | - | 100% (324) | glycosyl transferase family protein |
| M. gilvum PYR-GCK | Mflv_2187 | - | 3e-07 | 37.63% (93) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1240 | - | 2e-07 | 33.64% (107) | putative glucosyl-3-phosphoglycerate synthase |
| M. tuberculosis H37Rv | Rv1208 | - | 2e-07 | 33.64% (107) | putative glucosyl-3-phosphoglycerate synthase |
| M. leprae Br4923 | MLBr_01064 | - | 5e-08 | 31.82% (110) | putative glucosyl-3-phosphoglycerate synthase |
| M. abscessus ATCC 19977 | MAB_1346 | - | 1e-07 | 31.78% (107) | putative glucosyl-3-phosphoglycerate synthase |
| M. marinum M | MMAR_4230 | - | 4e-07 | 33.64% (107) | hypothetical protein MMAR_4230 |
| M. avium 104 | MAV_1353 | - | 6e-08 | 33.64% (107) | hypothetical protein MAV_1353 |
| M. smegmatis MC2 155 | MSMEG_5084 | - | 2e-07 | 36.56% (93) | glycosyl transferase, group 2 family protein |
| M. thermoresistible (build 8) | TH_4172 | - | 2e-12 | 29.05% (210) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0959 | - | 3e-07 | 33.64% (107) | putative glucosyl-3-phosphoglycerate synthase |
| M. vanbaalenii PYR-1 | Mvan_0217 | - | 1e-07 | 42.86% (84) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4230|M.marinum_M -MTASDLVTGDLTSEGVLIPARPGDTWLCDRSWNRPRWKIDELVEAK--A
MUL_0959|M.ulcerans_Agy99 -MTASDLVTGNLTSEGVLIPARPGDTWLCDRSWNRPRWKIDEVVEAK--A
MAV_1353|M.avium_104 -MTTSDLVAGELAGDG-LRDTRPGDTWLADRSWNRPGWTVAELEAAK--G
Mb1240|M.bovis_AF2122/97 -MTASELVAGDLAGGR-----APG-ALPLDTTWHRPGWTIGELEAAK--A
Rv1208|M.tuberculosis_H37Rv -MTASELVAGDLAGGR-----APG-ALPLDTTWHRPGWTIGELEAAK--A
MLBr_01064|M.leprae_Br4923 -MTASELIASALAARS-------GDAWLADRSWSRPAWTIDELVAAK--A
MAB_1346|M.abscessus_ATCC_1997 -MTSTVGIDSSWMSPA-----PQLPGWLETHSWNRPEWTVEQLIAAK--K
MSMEG_5084|M.smegmatis_MC2_155 ------------MG----------HRWLTDHSWNRPSWTVADLEAAK--A
Mvan_0217|M.vanbaalenii_PYR-1 ---MGELPATGHVGSAS--------HQGQTTTSSPHAQFMLARDGVK--V
Mflv_4770|M.gilvum_PYR-GCK ---MSEVIQPRRVSAV----------IRAYNEGKHIGRLLKGLEQQT--V
TH_4172|M.thermoresistible__bu VPSTDRLLHPDLLASIP---------FGETLTGRLLERRVTEALADDPNA
. :
MMAR_4230|M.marinum_M GRSISVVLPALDEEETIQSVIDSISPLVD---GLVDELIVLDSGSTDDTE
MUL_0959|M.ulcerans_Agy99 GRSISVVLPALDEEETIQSVIDSISPLVD---GLVDELIVLDSGSTDDTE
MAV_1353|M.avium_104 GRTISVVLPALDEEDTIGSVIDSISPLVD---GLVDELIVLDSGSTDDTE
Mb1240|M.bovis_AF2122/97 GRTISVVLPALNEEATIESVIDSISPLVD---GLVDELIVLDSGSTDDTE
Rv1208|M.tuberculosis_H37Rv GRTISVVLPALNEEATIESVIDSISPLVD---GLVDELIVLDSGSTDDTE
MLBr_01064|M.leprae_Br4923 GRAISVVLPALNEEQTIESVIDSISPLVSDRAGLVDELIVLDSGSTDETE
MAB_1346|M.abscessus_ATCC_1997 GRTVSVVLPALNEQETVAAVIDTISPLLG---GLVDELIVLDSGSTDDTA
MSMEG_5084|M.smegmatis_MC2_155 GRTVSVVLPALNEEETVGSVVETIKPLLG---GLVDELIVLDSGSTDETE
Mvan_0217|M.vanbaalenii_PYR-1 TPSVSLVIPVRNEARNVAWVLEQITEDVD-------EIILVDGASTDATL
Mflv_4770|M.gilvum_PYR-GCK RVDEIILVDSGSTDDTVAIAEAAGCKIVAIAKSEFSFGRALNRGCAAASG
TH_4172|M.thermoresistible__bu DPNVTVVVRTLNEAATLELLLLDVRRQAF---AAEVEIIVVDNESTDGTP
::: . .: :: .: :
MMAR_4230|M.marinum_M IRAIAAGARVVSREQALPEVPPQPGKGEALWRSLAATSGDIVVFIDSDLV
MUL_0959|M.ulcerans_Agy99 IRAIAAGARVVSREQALPEVPPQPGKGEALWRSLAATSGDIVVFIDSDLV
MAV_1353|M.avium_104 IRAVAAGARVVSREQALPEVPIRPGKGEALWRSLAASRGDIVVFVDSDLI
Mb1240|M.bovis_AF2122/97 IRAIASGARVVSREQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLI
Rv1208|M.tuberculosis_H37Rv IRAIASGARVVSREQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLI
MLBr_01064|M.leprae_Br4923 IRAIAAGARVVSCEQAMPEVPTRPGKGEALWRSLAVTSGDIVVFVDSDLI
MAB_1346|M.abscessus_ATCC_1997 IRAVAAGARVVSREQALPEVPPNPGKGEVLWRSVAATTGDLIAFVDSDLI
MSMEG_5084|M.smegmatis_MC2_155 IRAVAAGAKVVSREAALPEVPPQPGKGEVLWRSLAATTGDIIAFVDSDLI
Mvan_0217|M.vanbaalenii_PYR-1 ITALRYRPDIKVVAQDG------VGKGSALRTGFFAASGDIIVMMDADGS
Mflv_4770|M.gilvum_PYR-GCK DILLFASAHVYPVYDTYVEHIVNAFDRQGVAIAYGRQVGDERTKFSESRV
TH_4172|M.thermoresistible__bu DVAKQFGARVVSFPRHEFTYP------RSMNLGMAAASHDIVFLTVGHAR
. : : . *
MMAR_4230|M.marinum_M NPNPMFVP---WLVGPLLTGEGIHLVKSFYRRPLSVGDASGAAGATGGGR
MUL_0959|M.ulcerans_Agy99 NPNPMFVP---WLVGPLLTGEGIHLVKSFYRRPLSVGDASGAAGATGGGR
MAV_1353|M.avium_104 NPHPMFVP---WLVGPLLTGDGVHLVKSFYRRPLNVGDAGGGAGATGGGR
Mb1240|M.bovis_AF2122/97 NPHPLFVP---WLVGPLLTGEGIQLVKSFYRRPLQVSDVTSGVCATGGGR
Rv1208|M.tuberculosis_H37Rv NPHPLFVP---WLVGPLLTGEGIQLVKSFYRRPLQVSDVTSGVCATGGGR
MLBr_01064|M.leprae_Br4923 NPHPMFVP---WLVGPLLTGDGIHLVKGFYRRPLNSNDAGGSARATGGGR
MAB_1346|M.abscessus_ATCC_1997 DPDPMFVP---HLLGPLLLGQGIHLVKGFYRRPLKVS---GAEDANGGGR
MSMEG_5084|M.smegmatis_MC2_155 DPDPMFVP---KLLGPLLTCDGVHLVKGFYRRPLKVS---GAEDANGGGR
Mvan_0217|M.vanbaalenii_PYR-1 -------------MAPQEIRHYVHFLRNGYD-FVKGSRFIGGGGSLDITA
Mflv_4770|M.gilvum_PYR-GCK MLKWFPTENIWDQGHPFSNNANAAVLRSVWEESPYDEGLTGLEDLDFAQK
TH_4172|M.thermoresistible__bu LSTVHSLH------AGARHFRADDRVGGVFGTVLPNAGASWIERFAAALD
: . :
MMAR_4230|M.marinum_M VTELVARPLLAALRPELGCVLQPLS-GEYAASRELLTSLPFAP-GYGVEI
MUL_0959|M.ulcerans_Agy99 VTELVARPLLAALRPELGCVLQPLS-GEYAASRELLTSLPFAP-GYGVEI
MAV_1353|M.avium_104 VTELVARPLLAALRPELGCILQPLG-GEYAATRELLTSVPFAP-GYGVEI
Mb1240|M.bovis_AF2122/97 VTELVARPLLAALRPELGCVLQPLS-GEYAASRELLTSLPFAP-GYGVEI
Rv1208|M.tuberculosis_H37Rv VTELVARPLLAALRPELGCVLQPLS-GEYAASRELLTSLPFAP-GYGVEI
MLBr_01064|M.leprae_Br4923 VTELVARPLLASLRPQLGYVLQPLS-GEYAATRELLTALPFAP-GYGVEI
MAB_1346|M.abscessus_ATCC_1997 VTELVARPMLAALRPELSCVVQPLG-GEYAGTRELLSSVPFAP-GYGVEI
MSMEG_5084|M.smegmatis_MC2_155 VTELVARPLLASLRPELNCVLQPLG-GEYAGTRELLTSVPFAP-GYGVEI
Mvan_0217|M.vanbaalenii_PYR-1 FRKLGNRFLLGVFNSLYDSDLTDLCYGFCAFHRRYLELLELSATGFEIEA
Mflv_4770|M.gilvum_PYR-GCK ALAAGHKIAYVADAPVVHVHEESWEITRNRYRREAIAYAHIVE-GSEMSL
TH_4172|M.thermoresistible__bu TNRGLVRPAHRVRRTGQGVLGATGAMISKSVWEELGRFDERYETGGEDTA
: . .. *
MMAR_4230|M.marinum_M GLLVDTFDR-LGLDAIAQVNLGVRAHRNRPLAELGVMSRQVIATLLSRCG
MUL_0959|M.ulcerans_Agy99 GLLVDTFDR-LGLDAIAQVNLGVRAHRNRPLAELGVMSRQVIATLLSRCG
MAV_1353|M.avium_104 GLLVDTFDR-LGLDAIAQVNLGVREHRNRPLAELGAMSRQVIATLLSRCG
Mb1240|M.bovis_AF2122/97 GLLIDTFDR-LGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCG
Rv1208|M.tuberculosis_H37Rv GLLIDTFDR-LGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCG
MLBr_01064|M.leprae_Br4923 GLLVDTFDR-LGLDAIAQVNLGVRAHRNRPLAELGAMSRQVIATLLSRCG
MAB_1346|M.abscessus_ATCC_1997 GLLIDTYDK-LGLGSIAQVNLGVRSHRNRPLVELGVMSRQVMATMLSRCG
MSMEG_5084|M.smegmatis_MC2_155 GLLVDTYDR-LGLDGIAQVNLGVRAHRNRPLTELASMSRQVIATLLSRCG
Mvan_0217|M.vanbaalenii_PYR-1 EMTVRAMQAGLRIAEVPSLEMPRRSGKSN-LRAVRDGTRVLRTVLHGHR-
Mflv_4770|M.gilvum_PYR-GCK SRAVGLALS--NIVGDYIDAAKAKRIRGNLLSIPLFRSAQFLGAWEGFRA
TH_4172|M.thermoresistible__bu LAGLMLANG------YEVVREPALSVHHSHALGLRDTVRQLLHQRRTLRA
: : .
MMAR_4230|M.marinum_M IPDSGVGLTQFFAEG---DGYTECTSPVSLADRPPMSVLRPR-
MUL_0959|M.ulcerans_Agy99 IPDSGVGLTQFFAEG---DGYTECTSPVSLADRPPMSVLRPR-
MAV_1353|M.avium_104 IPDSGVGLTQFVADGPEGQSYTQHTWPVSLADRPPMQAIRPR-
Mb1240|M.bovis_AF2122/97 IPDSGVGLTQFLPGGPDDSDYTRHTWPVSLVDRPPMKVMRPR-
Rv1208|M.tuberculosis_H37Rv IPDSGVGLTQFLPGGPDDSDYTRHTWPVSLVDRPPMKVMRPR-
MLBr_01064|M.leprae_Br4923 ILDSGVGLTQFFVDESDGDGYIRHTWSVSLADRPAMSRLRPR-
MAB_1346|M.abscessus_ATCC_1997 IPDSGVGITQFFADG---DGFTPRSSTVSLEDRPPMNTLR---
MSMEG_5084|M.smegmatis_MC2_155 ISDSGVGLTQFFADG---DDFTPRVSSVSLADRPPMTTLRPR-
Mvan_0217|M.vanbaalenii_PYR-1 ------------------SGVSGHLLEVLSQRRGPAAAAAEAC
Mflv_4770|M.gilvum_PYR-GCK PANVSARLLERFYYPADSQSYDLPPAPGRRILYSDDMSISHQ-
TH_4172|M.thermoresistible__bu P---------------------QRLNRTELLERRPDLRV----