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M. gilvum PYR-GCK Mflv_4748 (-)

annotation: GtrA family protein
coordinates: 5057338 - 5058021
length: 227

VSFADATIRRLPGPIRPYAERHHELIKFAIVGATTFVIDSAIFFTLKLTILEPKPVTAKIIAGIVAVIAS
YILNREWSFRDRGGRERHHEALLFFGVSGVGVLLSMAPLWVSSYVLMLRVPMVSLMTENIADFVSAYIIG
NLLQMAFRFWAFRRFVFPDEFARNPEKALESTLTGGGLAEALEDEYELRHPHGPEPKGNVTPMRMSRRRR
NQRQRNDSDEPRVSKTS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4748--100% (227)GtrA family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3305-3e-9677.53% (227) transmembrane protein
M. tuberculosis H37RvRv3277-1e-9677.63% (228) transmembrane protein
M. leprae Br4923MLBr_00734-5e-8870.82% (233) hypothetical protein MLBr_00734
M. abscessus ATCC 19977-----
M. marinum MMMAR_1259-3e-8974.77% (222) hypothetical protein MMAR_1259
M. avium 104MAV_4247-7e-9275.00% (228) hypothetical protein MAV_4247
M. smegmatis MC2 155MSMEG_1817-1e-10585.46% (227) transmembrane protein
M. thermoresistible (build 8)TH_0888-1e-10080.43% (230) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_2629-6e-9575.00% (236) hypothetical protein MUL_2629
M. vanbaalenii PYR-1Mvan_1712-1e-11491.63% (227) GtrA family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3305|M.bovis_AF2122/97            MNEVTAGVRELATAIMVSRHLTGVLAGHGSQTVTYHFASILCSSVHSLVV
Rv3277|M.tuberculosis_H37Rv         MNEVTAGVRELATAIMVSRHLTGVLAGHGSQTVTYHFASILCSSVHSLVV
MMAR_1259|M.marinum_M               --------------------------------------------------
MUL_2629|M.ulcerans_Agy99           -------------------------------------------------M
MLBr_00734|M.leprae_Br4923          -------------------------------------------------M
MAV_4247|M.avium_104                -------------------------------------------------M
Mflv_4748|M.gilvum_PYR-GCK          -------------------------------------------------M
Mvan_1712|M.vanbaalenii_PYR-1       --------------------------------MTARCGIWAPGSVNWLLV
MSMEG_1817|M.smegmatis_MC2_155      -------------------------------------------------M
TH_0888|M.thermoresistible__bu      -------------------------------------------------V
                                                                                      

Mb3305|M.bovis_AF2122/97            SFADATIARLPGVVQPYAQRHHELIKFAIVGGTTFIIDTAIFYTLKLTVL
Rv3277|M.tuberculosis_H37Rv         SFADATIARLPGVVQPYAQRHHELIKFAIVGGTTFIIDTAIFYTLKLTVL
MMAR_1259|M.marinum_M               ------------MVQPFAQRHHELIKFAIVGGTTFIIDSAIFYTLKLTIL
MUL_2629|M.ulcerans_Agy99           SFADATIARLPRVVQPFAQRHHELIKFAIVGGTTFIIDSAIFYTLKLTIL
MLBr_00734|M.leprae_Br4923          SFPDATITRLPTVLQPYAQRYHELIKFAIVGGTTFIIDSAIFYTLKLTIL
MAV_4247|M.avium_104                SFAEATIARLPRLLQPYLLRHHELIKFAIVGGTTFVIDSAIFYTLKLTIL
Mflv_4748|M.gilvum_PYR-GCK          SFADATIRRLPGPIRPYAERHHELIKFAIVGATTFVIDSAIFFTLKLTIL
Mvan_1712|M.vanbaalenii_PYR-1       SFADATIRRLPGPIRPYAERHHELIKFAIVGATTFVIDSAIFFTLKLTIL
MSMEG_1817|M.smegmatis_MC2_155      SFADATIARLPRFIRPFAERHHELIKFAIVGATTFVIDSAIFYTLKLTVL
TH_0888|M.thermoresistible__bu      SFADATIARLPRPIRPYAERHHELIKFAIVGATTFIIDSAIFYTLKLTVL
                                                 ::*:  *:**********.***:**:***:*****:*

Mb3305|M.bovis_AF2122/97            EPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVG
Rv3277|M.tuberculosis_H37Rv         EPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVG
MMAR_1259|M.marinum_M               EPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVG
MUL_2629|M.ulcerans_Agy99           EPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVG
MLBr_00734|M.leprae_Br4923          EPKPVTAKVVAGIVAVIASYVLNREWSFRDRGGRERHNEALLFFAFSGIG
MAV_4247|M.avium_104                EPKPVTAKVIAGIVAVIASYVLNREWSFRNRGGRERHHEALLFFAFSGVG
Mflv_4748|M.gilvum_PYR-GCK          EPKPVTAKIIAGIVAVIASYILNREWSFRDRGGRERHHEALLFFGVSGVG
Mvan_1712|M.vanbaalenii_PYR-1       EPKPVTAKIIAGIVAVIASYILNREWSFRDRGGRERHHEALLFFGVSGVG
MSMEG_1817|M.smegmatis_MC2_155      EPKPVTAKIIAGIVAVIASYILNREWSFRDRGGRERHHEAFLFFAVSGVG
TH_0888|M.thermoresistible__bu      EPKPVTAKIIAGIVAVIASYILNREWSFRDRGGRERHHEALLFFGVSGVG
                                    ********::**********:********:*******:**:***..**:*

Mb3305|M.bovis_AF2122/97            VLLSMAPLWFSSYILQLRVPTVSLTMENIADFISAYIIGNLLQMAFRFWA
Rv3277|M.tuberculosis_H37Rv         VLLSMAPLWFSSYILQLRVPTVSLTMENIADFISAYIIGNLLQMAFRFWA
MMAR_1259|M.marinum_M               VLLSMAPLWFSSYVLQLRVPMVSLTVENLADFVSAYIIGNLLQMAFRFWA
MUL_2629|M.ulcerans_Agy99           VLLSMAPLWFSSYVLQLRVPMVSLTVENLADFVSAYIIGNLLQMAFRFWA
MLBr_00734|M.leprae_Br4923          VLLSMAPLWFSSYVLQLRAPTVSLTVENLADFLSAYIIGNLLQMAFRFWA
MAV_4247|M.avium_104                VLLSMAPLWFSSYVLQLRQPTVSLTVENVADFISAYIIGNLLQMAFRFWA
Mflv_4748|M.gilvum_PYR-GCK          VLLSMAPLWVSSYVLMLRVPMVSLMTENIADFVSAYIIGNLLQMAFRFWA
Mvan_1712|M.vanbaalenii_PYR-1       VLLSMAPLWVSSYVLMLRVPMVSLAAENVADFISAYIIGNLLQMAFRFWA
MSMEG_1817|M.smegmatis_MC2_155      VLLSMAPLWISSYVLMLRVPEVSLTTENIADFISAYIIGNLLQMAFRFWA
TH_0888|M.thermoresistible__bu      VVLSMAPLWISSYVLMLRAPMVSLTVENVADFISAYIIGNLLQMAFRFWA
                                    *:*******.***:* ** * ***  **:***:*****************

Mb3305|M.bovis_AF2122/97            FRRWVFPDEFARNPDKALESALTAGGIAEVFEDVLEGGFEDGNVT--LLR
Rv3277|M.tuberculosis_H37Rv         FRRWVFPDEFARNPDKALESALTAGGIAEVFEDVLEGGFEDGNVT--LLR
MMAR_1259|M.marinum_M               FRRWVFPDEFARNPDKALESALTAGGIAEVFEDEIEGG----NVT--LLR
MUL_2629|M.ulcerans_Agy99           FRRWVFPDEFARNPDKALESALTAGGIAEVFEDEIEGG----NVT--LLR
MLBr_00734|M.leprae_Br4923          FRRWVFPDAFARNPEKTLESALTAGGIAEVFEDAIDGVFEDFGDA--LLR
MAV_4247|M.avium_104                FRRWVFPDQFARDPDKALESALTAGGIAEIFEDAFEDD--GGNVT--LLR
Mflv_4748|M.gilvum_PYR-GCK          FRRFVFPDEFARNPEKALESTLTGGGLAEALEDEYELRHPHGPEPKGNVT
Mvan_1712|M.vanbaalenii_PYR-1       FRRFVFPDEFARNPEKALESTLTGGGFAEVLEDEYELRHPSGPD---NVT
MSMEG_1817|M.smegmatis_MC2_155      FRRFVFPDEFARNPDKALESTLTGGGLAEALEDEYEVSH--GPDS--VVT
TH_0888|M.thermoresistible__bu      FRRWVFPDEFGRAPDKALESTFTAGGLAEALEDHLEAHSERSSN----VT
                                    ***:**** *.* *:*:***::*.**:** :**  :            : 

Mb3305|M.bovis_AF2122/97            AWRNRANR--------FAQLGDSSEPRVSKTL
Rv3277|M.tuberculosis_H37Rv         AWRNRANR--------FAQLGDSSEPRVSKTS
MMAR_1259|M.marinum_M               SWRNKSARANRSDARSAAQLGASSEPRVSKTS
MUL_2629|M.ulcerans_Agy99           SWRNKSARANRSDARSAAQLGASSEPRVSKTS
MLBr_00734|M.leprae_Br4923          AWRNRSRRLDLS---PASQLGDSSEPRVSKTS
MAV_4247|M.avium_104                AWRNRAGR--------LTQLGDSSEPRVSKTS
Mflv_4748|M.gilvum_PYR-GCK          PMR-MSRRR-----RNQRQRNDSDEPRVSKTS
Mvan_1712|M.vanbaalenii_PYR-1       PMR-PSRRR-----WKQRP-SDPSEPRVSKTS
MSMEG_1817|M.smegmatis_MC2_155      PMR-RSRGR-----GAPPQLGDSSDPRVSKTS
TH_0888|M.thermoresistible__bu      PLHGRARLRSG---RHSRQLGDSSDPRVSKTS
                                    . :  :              . ..:******