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SDELFVVTVTYSPGPHLERFLATLAHATDRPVTVIIADNGSTDGAPEEAVERHPNARLFRTGGNLGYGTA VNRAVTEYGLASSTDFFIVANPDVQWGPHSIDLLCEAAQRWPQAGSLGPLIRDPDGAIYPSARHQPSIIR GGMHAVVAPVWPSNPWTAAYRQDRAEPSERTVGWLSGSCLLLRTAAFAQIDGFNERYFMYMEDVDLGDRL ETAGWQNVYVPSAEVLHAKGHATGRDPARNLAAHHVSTYTFLADRYPKWWQAPLRWAFRTALGARASLVV RRSRRKSRQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4735 | - | - | 100% (291) | glycosyl transferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3293c | wbbL1 | 1e-121 | 69.44% (288) | dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol |
| M. tuberculosis H37Rv | Rv3265c | wbbL1 | 1e-120 | 68.73% (291) | dTDP-RHA:A-D-GlcNAc-diphosphoryl polyprenol |
| M. leprae Br4923 | MLBr_00752 | wbbL | 1e-121 | 69.39% (294) | putative dTDP-rhamnosyl transferase |
| M. abscessus ATCC 19977 | MAB_3612c | - | 1e-112 | 65.51% (287) | putative dTDP-rhamnosyltransferase |
| M. marinum M | MMAR_1276 | wbbL1 | 1e-125 | 72.57% (288) | dTDP-rha:A-D-GlcNAc-diphosphoryl polyprenol A-3- |
| M. avium 104 | MAV_4230 | - | 1e-119 | 70.92% (282) | dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl |
| M. smegmatis MC2 155 | MSMEG_1826 | - | 1e-132 | 77.94% (281) | dTDP-RhA:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl |
| M. thermoresistible (build 8) | TH_0780 | wbbL | 1e-135 | 77.16% (289) | PROBABLE dTDP-RHA:A-D-GlcNAc-DIPHOSPHORYL POLYPRENOL, |
| M. ulcerans Agy99 | MUL_2611 | wbbL1 | 1e-124 | 72.22% (288) | dTDP-rha:A-D-GlcNAc-diphosphoryl polyprenol A-3- |
| M. vanbaalenii PYR-1 | Mvan_1728 | - | 1e-150 | 85.57% (291) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4735|M.gilvum_PYR-GCK ------MSD-----ELFVVTVTYSPGPHLERFLATLAHATDRPVTVIIAD
Mvan_1728|M.vanbaalenii_PYR-1 ------MSD-----ELFVVTVTYSPGPHLDRFLATLSLATDRPVTVIMAD
MSMEG_1826|M.smegmatis_MC2_155 ----------------MVVTVTYSPGPHLDRFLSSLSLATDRPVTVIMAD
TH_0780|M.thermoresistible__bu ------VSD-----HLVVVTVTYSPGPHLERFLASLEHATERPVTVIMAD
MMAR_1276|M.marinum_M ------MTD-----VLPVVAVTYSPGPHLERFLASLSLATDRPVSVLLAD
MUL_2611|M.ulcerans_Agy99 ------MTD-----VLPVVAVTYSPGPHLERFLASLSLATDRPVSVLLAD
MLBr_00752|M.leprae_Br4923 ------MTD-----VLPVVAVTYSPGPHLERFLASLALATDRPVSVVLAD
Mb3293c|M.bovis_AF2122/97 -----------------MVAVTYSPGPHLERFLASLSLATERPVSVLLAD
Rv3265c|M.tuberculosis_H37Rv -----------------MVAVTYSPGPHLERFLASLSLATERPVSVLLAD
MAV_4230|M.avium_104 --------------MLPVVTVTYSPGPHLERFLASLSLATEREVCVLLAD
MAB_3612c|M.abscessus_ATCC_199 MLDPHRVSDSPAIGQVAVVTVTYSPGEHLHRFLRTLRHATDLPLRVILAD
:*:****** **.*** :* **: : *::**
Mflv_4735|M.gilvum_PYR-GCK NGSTDGAPEEAVERHPNARLFRTGGNLGYGTAVNRAVTEYGLASS-----
Mvan_1728|M.vanbaalenii_PYR-1 NGSTDGAPEEAVERYRNVNLFRTGDNLGYGTAVNRAVAEYGLTSR-----
MSMEG_1826|M.smegmatis_MC2_155 NGSTDGTPEEAEQRYPNVRLLRTGANLGYGSAVNRAVAQLTAGEG-----
TH_0780|M.thermoresistible__bu NGSTDGAPEEALERYPNVRLMRTGANLGYGTAINRAVAEHLADTDP----
MMAR_1276|M.marinum_M NGSTDGTPQAAVERYPNVRIFHTGANLGYGTAVNRAVAQLTE------QP
MUL_2611|M.ulcerans_Agy99 NGSTDGTPQAAVERYPNVRIFHTGANLGYGTAVNRAVAQLTE------QP
MLBr_00752|M.leprae_Br4923 NGSTDGTPQVAVERYVNVRLFETGANLGYGTAANLAIAQFFEEGGATGQP
Mb3293c|M.bovis_AF2122/97 NGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDAGEP
Rv3265c|M.tuberculosis_H37Rv NGSTDGTPQAAVQRYPNVRLLPTGANLGYGTAVNRTIAQLGEMAGDAGEP
MAV_4230|M.avium_104 NGSTDGTPQAAVERYPNVRLFHTGANLGYGTAVNRAVAQLDR--------
MAB_3612c|M.abscessus_ATCC_199 NGSTDGAPEAAAE-EPDVELLRTGGNVGYGKAANLGVAQVDP--------
******:*: * : :..:: ** *:***.* * :::
Mflv_4735|M.gilvum_PYR-GCK --TDFFIVANPDVQWGPHSIDLLCEAAQRWPQAGSLGPLIRDPDGAIYPS
Mvan_1728|M.vanbaalenii_PYR-1 --SDFFIVANPDVQWGPRSIDLLLEAAARWPRAGALGPLIRDPDGAVYPS
MSMEG_1826|M.smegmatis_MC2_155 --TDFLVVANPDVQWGPKAIDLLLEASDRWPHAGAFGPLIRDPDGAIYPS
TH_0780|M.thermoresistible__bu --SDFFVVANPDVQWGPNSIDNLLAAAARWPRAAALGPLIRDADGSVYPS
MMAR_1276|M.marinum_M EPDDWLIVANPDVQWGPGSIDALLEAVERWPQAGALGPLIRDPDGSVYPS
MUL_2611|M.ulcerans_Agy99 EPDDWLIVANPDVQWGPGSIDALLEAVERWPQAGALGPLIRDPDGSVYPS
MLBr_00752|M.leprae_Br4923 WVDDWVIVANPDVQWGPGSIDALLDAAARWPRAGALGPLIRDPDGSVYPS
Mb3293c|M.bovis_AF2122/97 WVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPS
Rv3265c|M.tuberculosis_H37Rv WVDDWVIVANPDVQWGPGSIDALLDAASRWPRAGALGPLIRDPDGSVYPS
MAV_4230|M.avium_104 -GGEWVIVANPDVQWGPGSIDALLDAAARWPRAGALGPLVRDPDGSVYPS
MAB_3612c|M.abscessus_ATCC_199 -AAEWVVIANPDVQWGPGSIDAMLEVAQRWPAAGAVGPLIREPDGTVYPS
::.::********* :** : . *** *.:.***:*:.**::***
Mflv_4735|M.gilvum_PYR-GCK ARHQPSIIRGGMHAVVAPVWPSNPWTAAYRQDRAEPSERTVGWLSGSCLL
Mvan_1728|M.vanbaalenii_PYR-1 ARHLPSIIRGGMHAVVGPVWPSNPWTTAYRQERADPSEREVGWLSGSCLL
MSMEG_1826|M.smegmatis_MC2_155 ARHQPSLLRGGLHAVVGPFWKNNPWTAAYRQDRQEPSERPVGWLSGSCLL
TH_0780|M.thermoresistible__bu AREQPSLIRGGMHAVIGPLWPGNPWTAAYRQDRMEPTERPVGWLSGSCLL
MMAR_1276|M.marinum_M ARHLPSLVRGGMHAVLGPVWPRNPWTKAYRQEHLEPSERPVGWLSGSCLL
MUL_2611|M.ulcerans_Agy99 ARHLPSLVRGGMHAVLGPVWPRNPWTKAYRQEHLEPSERPVGWLSGSCLL
MLBr_00752|M.leprae_Br4923 ARHLPSLVRGGMHAVLGPVWPRNPWTAAYRQERLELTERPVGWLSGSCLL
Mb3293c|M.bovis_AF2122/97 ARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGSCLL
Rv3265c|M.tuberculosis_H37Rv ARQMPSLIRGGMHAVLGPFWPRNPWTTAYRQERLEPSERPVGWLSGSCLL
MAV_4230|M.avium_104 ARHLPSLVRGGMHAVVGPFWKNNPWSTAYRQERLEPSERPVGWLSGSCLL
MAB_3612c|M.abscessus_ATCC_199 ARVVPTLTGGALHALLGSVWSTNPWTAAYRQDRMEPSERVVGWLSGSCLL
** *:: *.:**::...* ***: ****:: : :** **********
Mflv_4735|M.gilvum_PYR-GCK LRTAAFAQIDGFNERYFMYMEDVDLGDRLETAGWQNVYVPSAEVLHAKGH
Mvan_1728|M.vanbaalenii_PYR-1 LRSSAYSEIAGFDERYFMYMEDVDLGDRLGRAGWQNVYVPSAEVLHDKGH
MSMEG_1826|M.smegmatis_MC2_155 LRRNAFDAIGGFDERYFMYMEDVDLGDRLDRAGWQNIYVPSAEVLHYKGH
TH_0780|M.thermoresistible__bu LRKAAFDEVDGFDERYFMYMEDVDLGDRLAKAGWQNIYVPSSEILHYKGH
MMAR_1276|M.marinum_M VRRSAFRQIGGFDERYFMYMEDVDLGDRLGQAGWLSVYVPSAEVLHHKGH
MUL_2611|M.ulcerans_Agy99 VRRSAFRQIGGFDERYFMYMEDVDLGDRLGQAGWLSVYVPSAEVLHHKGH
MLBr_00752|M.leprae_Br4923 VRRSAFREVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKGH
Mb3293c|M.bovis_AF2122/97 VRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAH
Rv3265c|M.tuberculosis_H37Rv VRRSAFGQVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKAH
MAV_4230|M.avium_104 VRRSAFERVGGFDERYFMYMEDVDLGDRLGKAGWLSVYVPSAEVLHHKGH
MAB_3612c|M.abscessus_ATCC_199 LRRTAFDAIGGFDPRYFMYMEDVDLGDRLARAGWQNVYAPSSEVVHAKGH
:* *: : **: *************** *** .:*.**:*::* *.*
Mflv_4735|M.gilvum_PYR-GCK ATGRDPARNLAAHHVSTYTFLADRYPKWWQAPLRWAFRTALGARASLVVR
Mvan_1728|M.vanbaalenii_PYR-1 STGRDPARNLAAHHVSTYTFLADRYPRWWQAPLRWAFRGALGARASLVVR
MSMEG_1826|M.smegmatis_MC2_155 STGRDPARNLAAHHRSTYTFLADRYPATWQAPLRWAIRGALAVRAGLVVG
TH_0780|M.thermoresistible__bu AAGRDPARNLVAHHRSTYTFLADRYPRWWQSPLRWTIRGALAVRANLAVG
MMAR_1276|M.marinum_M STGRDPANHLAAHHRSTYIFLADRHAGWWRAPLRWTLRGSLAVRSRLMVR
MUL_2611|M.ulcerans_Agy99 STGRDPATHLAVHHRSTYIFLADRHAGWWRAPLRWTLRGSLAVRSRLMVR
MLBr_00752|M.leprae_Br4923 STGRDPVSHLAAHHKSTYIFLADRHSGWWRAPLRWMLRGSLVVRSRLMVR
Mb3293c|M.bovis_AF2122/97 STGRDPASHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVR
Rv3265c|M.tuberculosis_H37Rv STGRDPASHLAAHHKSTYIFLADRHSGWWRAPLRWTLRGSLALRSHLMVR
MAV_4230|M.avium_104 STGADPASHLAAHHRSTYMFLADRYSGWMRAPLRWALRASLAVRARLMVR
MAB_3612c|M.abscessus_ATCC_199 AAGRDPARSLGAHHDSVYIFQSDRHPHWWQAPLRWSIRGALAARSAIVVR
::* **. * .** *.* * :**:. ::**** :* :* *: : *
Mflv_4735|M.gilvum_PYR-GCK -----RSRRKS-----RQS---------------------
Mvan_1728|M.vanbaalenii_PYR-1 -----NSRRKT-----RRT---------------------
MSMEG_1826|M.smegmatis_MC2_155 -----NSRRK-------RANKG----------------AW
TH_0780|M.thermoresistible__bu -----NSRRKQ-----ARVRPGEERPARNPARNTDMGTTW
MMAR_1276|M.marinum_M -----SSRRK--------LVEGRH----------------
MUL_2611|M.ulcerans_Agy99 -----SSRRK--------LVEGRH----------------
MLBr_00752|M.leprae_Br4923 -----SSRRKQAAKQARQLAEGRR----------------
Mb3293c|M.bovis_AF2122/97 ----RSRRRK------LKLVEGRH----------------
Rv3265c|M.tuberculosis_H37Rv SSLRRSRRRK------LKLVEGRH----------------
MAV_4230|M.avium_104 -----SALRE-----SGRRVEGRH----------------
MAB_3612c|M.abscessus_ATCC_199 -----AAIRAN----RRRDKQGG-----------------
*