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MGRKHAIVIGASLGGLCAARVLSSAFDDVTVFERDPLPEGPANRPAVPQGRHVHLLMARGAAEFETLFPG LLDDMVACGVPILENRPDCIHFGAAGHLLGTTHRLQDEFTAYVPSRPHLEWQIRRRVLALDNVRLIDCGV DEPVYDGHRVTGVRTADGATVDADFVVDATGRGTRLPTWLSQWGFERPREDTVDVGISYATHQLRIPDGL IDEKVIVVGASRTQPRGLGMLYYEDGTWGLTTFGVGKVPAPTDFNEMRELAEELLPAHIGAALYQTHPLG DVALHKYPTSRWRRFDELDRYPRGILPFGDAVASFNPTFGQGMTMTSLQAGHLQRALQEPEPEATFLAAT AKSTWPVWTMNAIGDLTMHGADGPAPWWYRPVGALFDQFLGAAESDPVLAEWFLRRFSLLDSLYMVPSAR LIGRTVRHNMTLWARSRRSPGTASSAPAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4723 | - | - | 100% (449) | hypothetical protein Mflv_4723 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3282 | - | 1e-169 | 64.50% (462) | hypothetical protein Mb3282 |
| M. tuberculosis H37Rv | Rv3254 | - | 1e-169 | 64.50% (462) | hypothetical protein Rv3254 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1628c | - | 1e-59 | 34.71% (461) | hypothetical protein MAB_1628c |
| M. marinum M | MMAR_1288 | - | 1e-167 | 64.78% (460) | hypothetical protein MMAR_1288 |
| M. avium 104 | MAV_4218 | - | 1e-168 | 64.35% (460) | hypothetical protein MAV_4218 |
| M. smegmatis MC2 155 | MSMEG_1837 | - | 1e-154 | 58.66% (433) | secreted protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2599 | - | 1e-163 | 64.13% (460) | hypothetical protein MUL_2599 |
| M. vanbaalenii PYR-1 | Mvan_5929 | - | 1e-92 | 41.39% (447) | hypothetical protein Mvan_5929 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3282|M.bovis_AF2122/97 --------------------MVIGASIAGLCAARVLSDFYSTVTVFERDE
Rv3254|M.tuberculosis_H37Rv --------------------MVIGASIAGLCAARVLSDFYSTVTVFERDE
MMAR_1288|M.marinum_M --------MRGTLSTSNNHALVIGASIAGLCAARVLSDFFHRVTLIERDE
MUL_2599|M.ulcerans_Agy99 ------------MSTSNNHALVIGASIAGLCAARVLSDFFHRVTLIERDE
MAV_4218|M.avium_104 --------MPDGKANAREHALVIGGSIAGLCAARVLSESYSAVTVCERDE
Mflv_4723|M.gilvum_PYR-GCK --------------MGRKHAIVIGASLGGLCAARVLSSAFDDVTVFERDP
MSMEG_1837|M.smegmatis_MC2_155 MFPLPWQSMSTTLEHSSTHAIVIGGSVAGLCAARVLSDHFDRVTVYERDE
MAB_1628c|M.abscessus_ATCC_199 ----MTPH----VRDHRDHAVVLGAGMAGLLAARVLSESYASVTVVERDE
Mvan_5929|M.vanbaalenii_PYR-1 ----MNPDGPLVMNNLGDHAVVLGASMGGLLAARVLADFYRTVTIVERDV
:*:*..:.** *****:. : **: ***
Mb3282|M.bovis_AF2122/97 LPEAPANRATVPQDRHLHMLMARGAQEFDSLFPGLLHDMVAAGVPMLEN-
Rv3254|M.tuberculosis_H37Rv LPEAPANRATVPQDRHLHMLMARGAQEFDSLFPGLLHDMVAAGVPMLEN-
MMAR_1288|M.marinum_M LPSAPHGRATVPQDRHLHMLMARGANEFENLFPGLLTDMVAAGVPMLEN-
MUL_2599|M.ulcerans_Agy99 LPSVPHGRATVPQDRHLHMLMARGANEFENLFPGLLTDMVAAG-PMLEN-
MAV_4218|M.avium_104 LPAAPASRATVPQDRHLHLLMARGAIEFEKLFPGLLDDMTAAGVPRLHN-
Mflv_4723|M.gilvum_PYR-GCK LPEGPANRPAVPQGRHVHLLMARGAAEFETLFPGLLDDMVACGVPILEN-
MSMEG_1837|M.smegmatis_MC2_155 LPTEPVNRSAVPQGQHVHLLMARGAQELEAIFPGMLDDMARAGVPVVQN-
MAB_1628c|M.abscessus_ATCC_199 LHKVAAARSGVPQGHHIHMFMAAGTQGLEQLFPGILDDLRTDGATVCDEG
Mvan_5929|M.vanbaalenii_PYR-1 LPNDPVNRRGVPQGRHVHALLARGSRILEELFPGLLDEVVAGGAPVLDGT
* . * ***.:*:* ::* *: :: :***:* :: * . .
Mb3282|M.bovis_AF2122/97 RPDCIYLGAAGHVLG---TGHTLRKEFTAYVPSRPHLEWQLRRRVLQLSN
Rv3254|M.tuberculosis_H37Rv RPDCIYLGAAGHVLG---TGHTLRKEFTAYVPSRPHLEWQLRRRVLQLSN
MMAR_1288|M.marinum_M RPDCIYFAAAGHALG---TGHTLRKEFTAYVPSRPHLEWQLRRRVLELDN
MUL_2599|M.ulcerans_Agy99 RPDCIYFAAAGHALG---TGHTLRKEFTAYVPSRPHLEWQLRRRVLELDN
MAV_4218|M.avium_104 RPECIHLGAAGHVLG---TGQTLRDEFTAYVPSRPQLEWQLRKRVHAIGN
Mflv_4723|M.gilvum_PYR-GCK RPDCIHFGAAGHLLG---TTHRLQDEFTAYVPSRPHLEWQIRRRVLALDN
MSMEG_1837|M.smegmatis_MC2_155 QPESIHFTAGGHLLG---TGQTLESNFTAYVPTRGRLEWQIRERVLALPT
MAB_1628c|M.abscessus_ATCC_199 DLSRIRMLLGTHEMFNRTKKFSDPETFKLYLTTRPFLEFHVRQRVQRLGN
Mvan_5929|M.vanbaalenii_PYR-1 DPSEGYFRFGGHLLP-RDGRPKDP--ITLLLPSRPMLEYLVRQKVRGIPN
. : . * : :. :.:* **: :*.:* : .
Mb3282|M.bovis_AF2122/97 VQIVRR-LVTEPQFERRQQRVVGVLLDSPGSGQDREREEFIAADLVVDAA
Rv3254|M.tuberculosis_H37Rv VQIVRR-LVTEPQFERRQQRVVGVLLDSPGSGQDREREEFIAADLVVDAA
MMAR_1288|M.marinum_M IEIVRG-LVIEPRFEPTTQTVSGVLVAPPDD-DDGAEPQFLAADLVVDAA
MUL_2599|M.ulcerans_Agy99 IEIVRG-LVIEHRFEPTTQTVSGVLVAPPDD-DDGAEPQFLAADLVVDAA
MAV_4218|M.avium_104 VTVLRR-SVAQPRFDPARARVTGVWLDPVAG----GSAEFVAADLVVDAA
Mflv_4723|M.gilvum_PYR-GCK VRLIDC-GVDEPVYDG--HRVTGVRTADGAT---------VDADFVVDAT
MSMEG_1837|M.smegmatis_MC2_155 VSVLRG-GVAHPEFDAAAQRVTGVVLDNGET---------VEGDLVVDAS
MAB_1628c|M.abscessus_ATCC_199 VKFLDGHDVIEPMTAEH--RITGVRVARRST----GLVTTLICDLVVDAT
Mvan_5929|M.vanbaalenii_PYR-1 IAMLEAHDVVDLTSASQQDRVTGARVRARDN----GAERVLNAELVVDAT
: .: * . : *. : ::****:
Mb3282|M.bovis_AF2122/97 GRGTRLPVWLTQWGYRRPAEDTVDIGISYASHQFRIPDGLIAEKVVVAGA
Rv3254|M.tuberculosis_H37Rv GRGTRLPVWLTQWGYRRPAEDTVDIGISYASHQFRIPDGLIAEKVVVAGA
MMAR_1288|M.marinum_M GRGTRLPVWLSKWGYQRPAEQSMDIGINYASQQLRIPDGLIQEKVVVAGV
MUL_2599|M.ulcerans_Agy99 GRGTRLPVWLSKWGYQHPAEQSMDIGINYASQQLRIPDGLIQEKVVVAGV
MAV_4218|M.avium_104 GRGTRLPVWLSQWGFQRPPEEVIDIGINYATQHFRIPDGLIAQKVVVAGA
Mflv_4723|M.gilvum_PYR-GCK GRGTRLPTWLSQWGFERPREDTVDVGISYATHQLRIPDGLIDEKVIVVGA
MSMEG_1837|M.smegmatis_MC2_155 GRGSRLPVWLEEWGFERPREDSVKIGVTYASHRVRIPEGLMAEKMVLVSA
MAB_1628c|M.abscessus_ATCC_199 GRTPRTQTFLDRLGFARPAETRVASPVTYASQLLHVSEDTDLDKLTFLNA
Mvan_5929|M.vanbaalenii_PYR-1 GRGSRTPAFLDHLGYNRPAQDHIDVRLTYSSQLLRLPPGAVKERIVIVGP
** .* .:* . *: :* : : :.*::: .::. . ::: . .
Mb3282|M.bovis_AF2122/97 SHDQSLGLGMLCYEDGTWVLTTFGVADAKPPPTFDEMRALADKLLPARFT
Rv3254|M.tuberculosis_H37Rv SHDQSLGLGMLCYEDGTWVLTTFGVADAKPPPTFDEMRALADKLLPARFT
MMAR_1288|M.marinum_M AHDRSLGLGMLCYEDGTWVMTTFGVAGAKPPPTFGEMRALAERLLPARFN
MUL_2599|M.ulcerans_Agy99 AHDRSLGLGMLCYEDGTWVMTTFGVAGAKPPPTFGEMRALAERLLPARFN
MAV_4218|M.avium_104 SHDEPLGLGMLCYEDRVWVLTTFGVADAKPPRTFPEMLTLARRLLPAHFG
Mflv_4723|M.gilvum_PYR-GCK SRTQPRGLGMLYYEDGTWGLTTFGVGKVPAPTDFNEMRELAEELLPAHIG
MSMEG_1837|M.smegmatis_MC2_155 SHDDGLGMGMLFHEDGIWTVTAFGVAKAEPPKDLDGILAQADTMVPPHIS
MAB_1628c|M.abscessus_ATCC_199 APGRPFGGAIARCENDTVMMTLGQFNLDEPPTTFAEMITLAEQFVPHAVV
Mvan_5929|M.vanbaalenii_PYR-1 IPGRPTGMALFGYENATWIFTAIGMAGRESPAELTEMLTFVDDFTPPHVA
* .: *: .* . .* : : . : * .
Mb3282|M.bovis_AF2122/97 AALAQAQPIGCPAFHAFPASRWRRYDKLERFPRGIVPFGDAVASFNPTFG
Rv3254|M.tuberculosis_H37Rv AALAQAQPIGCPAFHAFPASRWRRYDKLERFPRGIVPFGDAVASFNPTFG
MMAR_1288|M.marinum_M AALAQSEPIGAPMFHAFPASKWRRYDKLDRFPAGIVPFGDAVASFNPTFG
MUL_2599|M.ulcerans_Agy99 AALAQSEPIGAPMFHAFPASKWRRYDKLDRFPAGIVPFGDAVASFNPTFG
MAV_4218|M.avium_104 DALARAEPLGDPAFHAFPASRWRRYDKLDRVPAGIVALGDAVASFNPTFG
Mflv_4723|M.gilvum_PYR-GCK AALYQTHPLGDVALHKYPTSRWRRFDELDRYPRGILPFGDAVASFNPTFG
MSMEG_1837|M.smegmatis_MC2_155 AALRAGEPVGGMNFHRYPVAKWRRYDKMRRWPAGIMPFGDAVASLNPTYG
MAB_1628c|M.abscessus_ATCC_199 ETLRSAEPVGAVHNFWYRDAVWRRYDEMDGFPEGLLVIGDAVCSLDPIRG
Mvan_5929|M.vanbaalenii_PYR-1 AALREAEPLADIARHRMPSSQWRRYDKMQRFPAGLLVFGDAICSFNPIYG
:* .*:. . : ***:*:: * *:: :***:.*::* *
Mb3282|M.bovis_AF2122/97 QGMTMTSLQAGHLRRALKARNSAMKGDLAAELNRATAKTTYPVWMMNAIG
Rv3254|M.tuberculosis_H37Rv QGMTMTSLQAGHLRRALKARNSAMKGDLAAELNRATAKTTYPVWMMNAIG
MMAR_1288|M.marinum_M QGMTMTSLQAGHLRRALQSP----HGDLATQLNRATAKTTYPVWTMNAIG
MUL_2599|M.ulcerans_Agy99 QGMTMTSLQAGHLRRALQSP----HGDLATQLNRATAKTTYPVWTMNAIG
MAV_4218|M.avium_104 QGMTMTALQAGHLRRALRCP----DDRLAAALYRATAKTTFPVWTMNAIG
Mflv_4723|M.gilvum_PYR-GCK QGMTMTSLQAGHLQRALQEP------EPEATFLAATAKSTWPVWTMNAIG
MSMEG_1837|M.smegmatis_MC2_155 QGVTMTALQAANLRTVLSVG----KQDLVSRLAYRTARTTFPVWMMNAVA
MAB_1628c|M.abscessus_ATCC_199 QGMTMALLEAAALRDCLFEG----DADLARRYFQTVGKRISTAWEHNRMT
Mvan_5929|M.vanbaalenii_PYR-1 QGMTVAALQAEALRKCLQHG----AAGLARRYFRATAKPISVAWRLAAG-
**:*:: *:* *: * ..: .*
Mb3282|M.bovis_AF2122/97 DISFHHATAE----PLPRWWRPAGSLFDQFLGAAETDPVLAEWFLRRFSL
Rv3254|M.tuberculosis_H37Rv DISFHHATAE----PLPRWWRPAGSLFDQFLGAAETDPVLAEWFLRRFSL
MMAR_1288|M.marinum_M DISFHHGLTQ----SPPAWWRPAGALFDQFLGAAETDPVLAEWFLRRFSL
MUL_2599|M.ulcerans_Agy99 DISFHHGLTQ----SPPAWWRPAGALFDQFLGAAETDPVLAEWFLRRFSL
MAV_4218|M.avium_104 DVTFHHATTKR---PAPWWWRPSGALFDQFLGAAETEPVLAEWFLRRFSL
Mflv_4723|M.gilvum_PYR-GCK DLTMHGADGP-----APWWYRPVGALFDQFLGAAESDPVLAEWFLRRFSL
MSMEG_1837|M.smegmatis_MC2_155 DHVAHGAEGP-----KPWWYRPMYSLFDQFLGAAETDPVLAEWFLRRTSL
MAB_1628c|M.abscessus_ATCC_199 APLHSSAPDSATFGQR-VKWNLMAWWSAKMLMAARNDIAITETILRVNNM
Mvan_5929|M.vanbaalenii_PYR-1 ADLNLHEVE----GRRPPSVRIANRYVDRLQRAAESDNVVAEQFVKVTGL
. :: **..: .::* ::: .:
Mb3282|M.bovis_AF2122/97 LDSLYMVPSVPIIGRAIAHNLRLWLKEQRE----RRQPVTTRRSP-
Rv3254|M.tuberculosis_H37Rv LDSLYMVPSVPIIGRAIAHNLRLWLKEQRE----RRQPVTTRRSP-
MMAR_1288|M.marinum_M LDSLYIVPPPRLIGRTIAHNVGLWLRERRQSASSRGRTLTAPRSP-
MUL_2599|M.ulcerans_Agy99 LDSLYIVPPPRLIGRTIAHNVGLWLRERRQSASSRGRTLTAPRSP-
MAV_4218|M.avium_104 LDSLYLIPPPRIVGRAVGHNMRLWLGQRRGAG--RPGTATARPSP-
Mflv_4723|M.gilvum_PYR-GCK LDSLYMVPSARLIGRTVRHNMTLWARSRRS-----PGTASSAPAR-
MSMEG_1837|M.smegmatis_MC2_155 LDSLYLAPSPRVIGRAIRHNASMWLAEKTN----RADRDKSLAATG
MAB_1628c|M.abscessus_ATCC_199 QDAPRSMRRPTFVLRVLRHCWRRHETSTAP----APQRQLTLSGV-
Mvan_5929|M.vanbaalenii_PYR-1 IDPPARLLHPKILLRVAFTSWRRRGRHR------------------
*. .: *.