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M. gilvum PYR-GCK Mflv_4430 (-)

annotation: aminoglycoside/hydroxyurea antibiotic resistance kinase
coordinates: 4715139 - 4715936
length: 265

VMAAWSLQADGQEYARTRAYVAPVRTSDGQAATLKIAAPGPGTAHEHLVLRRWDGHGAVRLLRADPHRRA
ILVERAGRDDLTAAPDRRACEIVAQLYRRLHVPAMPQLSSLTEDVRRRTLALADLPRSAPLPRRLVEQAI
TLGRELTVEPAERVVLHGNLHYRNALAADREPWLAISPRPCNGDPPYELAPMLWHRFDDLAGNVRDGVRQ
RFHRLVDGAGFDEDRARAWTLVRVVHAAADDLRTEPASATTQLTRYVAIAKAIQD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4430--100% (265)aminoglycoside/hydroxyurea antibiotic resistance kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_3480-1e-7654.74% (274) streptomycin 6-kinase (streptidine kinase)
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4430|M.gilvum_PYR-GCK          ---------MMAA----------------------WSLQADGQEYARTRA
MSMEG_3480|M.smegmatis_MC2_155      MIELPDAVRAMAARGPRWQTWVDGLAKLVRTQIGDWELTVDGAAMHGYCS
                                              ***                      *.* .**       :

Mflv_4430|M.gilvum_PYR-GCK          YVAPVRTSDGQAATLKIAAPGPGTAHEHLVLRRWDGHGAVRLLRADPHRR
MSMEG_3480|M.smegmatis_MC2_155      IVVPVRDRDGASAVLKLSFPDDETEHEHLALRRWGGHGAVRLLRADPHHR
                                     *.***  ** :*.**:: *.  * ****.****.*************:*

Mflv_4430|M.gilvum_PYR-GCK          AILVERAGRDDLTAAPDRRACEIVAQLYRRLHVPAMPQLSSLTEDVRRRT
MSMEG_3480|M.smegmatis_MC2_155      ALLLERLSNRNLNELWDIQACEIVADLYRALHVPALPQVRSLPRAVTRWT
                                    *:*:** .. :*.   * :******:*** *****:**: **.. * * *

Mflv_4430|M.gilvum_PYR-GCK          LALADLPRSAPLPRRLVEQAITLGRELTVEPAER-VVLHGNLHYRNALA-
MSMEG_3480|M.smegmatis_MC2_155      DGLAALPRSAPVPRRLVEQAITLGTDLATDPSSSGVLIHGDLHYENVLAG
                                     .** ******:************ :*:.:*:.  *::**:***.*.** 

Mflv_4430|M.gilvum_PYR-GCK          ---------ADREP--WLAISPRPCNGDPPYELAPMLWHRFDDLAGNVRD
MSMEG_3480|M.smegmatis_MC2_155      PVGSDDGDDTDGGPGSWVAIDPKPFDGDPHYELAPMLWNRWDELTGYVRE
                                             :*  *  *:**.*:* :*** ********:*:*:*:* **:

Mflv_4430|M.gilvum_PYR-GCK          GVRQRFHRLVDGAGFDEDRARAWTLVRVVHAAADDLRTEPASATTQLTRY
MSMEG_3480|M.smegmatis_MC2_155      GVRRRFYAVVDAAGLDADRARAWVIVRMMHNAMWELTERSEPDAHWLTTC
                                    ***:**: :**.**:* ******.:**::* *  :*  .. . :  **  

Mflv_4430|M.gilvum_PYR-GCK          VAIAKAIQD
MSMEG_3480|M.smegmatis_MC2_155      VAIAKAVQD
                                    ******:**