For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MGEPSRARGFNRRRLLLTGGAALAATTTLTRCGRAESATAATGFGSNSEPFHGAHQGGVDTPAQAHALFV ALDLVATPDRAPRDTLASVLRLWTADAARLTQGRPALADTEPELAARPSRLTVTVGLGAGLFERAGLSHR RPDSVTEVPAFSTDRLESRWCGGDLLLQICADDPLVVAHTARVLLKNVRTMTTQRWQQRGFRSARGSDTS GATMRNLMGQVDGTVNLRTATDVDRLVWDDGAGQPWFAGGTVLVLRRIRTELDSWDELDRTSRELTVGRR LDTGAPLTGTHEFDEPDLDAAENGIPVIPPNSHVALARHRHDGERFLRRAYNYDDPPTDATTDAGLIFAA FQRDPAQQFVPVQQRLAASDALNPWITTIGSAVFAILPGAADGGYLGQSLLE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4209 | - | - | 100% (402) | Dyp-type peroxidase family protein |
| M. gilvum PYR-GCK | Mflv_1950 | - | 3e-58 | 34.53% (417) | Dyp-type peroxidase family protein |
| M. gilvum PYR-GCK | Mflv_1627 | - | 5e-06 | 26.67% (225) | Dyp-type peroxidase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0822c | - | 2e-05 | 26.02% (196) | hypothetical protein Mb0822c |
| M. tuberculosis H37Rv | Rv0799c | - | 2e-05 | 26.02% (196) | hypothetical protein Rv0799c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2270c | - | 1e-129 | 59.25% (400) | putative peroxidase |
| M. marinum M | MMAR_4892 | - | 1e-06 | 26.53% (196) | hypothetical protein MMAR_4892 |
| M. avium 104 | MAV_2485 | - | 4e-72 | 42.24% (419) | Tat-translocated enzyme |
| M. smegmatis MC2 155 | MSMEG_6567 | - | 1e-140 | 63.87% (393) | iron-dependent peroxidase |
| M. thermoresistible (build 8) | TH_1583 | - | 1e-149 | 67.77% (394) | iron-dependent peroxidase |
| M. ulcerans Agy99 | MUL_0406 | - | 3e-07 | 27.04% (196) | hypothetical protein MUL_0406 |
| M. vanbaalenii PYR-1 | Mvan_2157 | - | 1e-175 | 75.96% (391) | Dyp-type peroxidase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4209|M.gilvum_PYR-GCK MGE---------------PSRARGFNRRRLLLTGGAALAATTTLTRCG--
Mvan_2157|M.vanbaalenii_PYR-1 MAE---------------QRWT--LNRRR-LLTGGAAVAAGAALTQCA--
TH_1583|M.thermoresistible__bu MGDR------------ADTARDITISRRRLLAGGAAAIGAAGAAWSVG--
MSMEG_6567|M.smegmatis_MC2_155 MAD----------------GSSMRVNRRRLLTGGAAALAAGAVVTASG--
MAB_2270c|M.abscessus_ATCC_199 -------------------MSSRSLSRRGLIVGGGAAAALTAGAGLSA--
MAV_2485|M.avium_104 MTDDPIEPTDGAPKSEGVEPDSTAVSRRRALGGAVLAGLSGAAIGAVGGG
Mb0822c|M.bovis_AF2122/97 -----------------------------------------MAVPAVS--
Rv0799c|M.tuberculosis_H37Rv -----------------------------------------MAVPAVS--
MMAR_4892|M.marinum_M -------------------------------------------MPSVQ--
MUL_0406|M.ulcerans_Agy99 -------------------------------------------MPSVQ--
Mflv_4209|M.gilvum_PYR-GCK RAESATAA--TGFGSNSE------PFHG-AHQGGVDTPAQAHALFVALDL
Mvan_2157|M.vanbaalenii_PYR-1 TAGSSTP---TGFGSATE------PFHG-RHQAGIATPPQAHALFVALDM
TH_1583|M.thermoresistible__bu RAGAGTVAPDTTFGAEVV------PFHG-VHQAGIQTPPQAHALFTALDL
MSMEG_6567|M.smegmatis_MC2_155 VANSAVVD--HGFGTDAE------PFYG-PHQAGIATAPQAHGVFLAFDV
MAB_2270c|M.abscessus_ATCC_199 WSAQSHAAR-PSAERQVE------PFYG-DHQAGIATAPQAHAMFLALDL
MAV_2485|M.avium_104 FAGHAVAAGQRGDDHDTVDLRRSYPFYGQPHQGGIDTPPQRYAMFMSFSL
Mb0822c|M.bovis_AF2122/97 -------------------------------PQPILAPLTPAAIFLVATI
Rv0799c|M.tuberculosis_H37Rv -------------------------------PQPILAPLTPAAIFLVATI
MMAR_4892|M.marinum_M -------------------------------PQPILAPLTPAAIFLVATI
MUL_0406|M.ulcerans_Agy99 -------------------------------PQPILAPLTPAAIFLVATI
: :. .:* :
Mflv_4209|M.gilvum_PYR-GCK VATPDR---APRDTLASVLRLWTADAARLTQGRPA-----------LADT
Mvan_2157|M.vanbaalenii_PYR-1 APSADR---SPRDTLIAMLRLWSSDAARLTAGQPA-----------LADT
TH_1583|M.thermoresistible__bu RADSGR---SPRQALTAVLRLWTADAERLTQGRPA-----------LADT
MSMEG_6567|M.smegmatis_MC2_155 KPTDTR---SERDTVAAILRLWTVDAARLTAGRPA-----------VADT
MAB_2270c|M.abscessus_ATCC_199 LSAADADMGTARENLRSILRLWTTDAARLTQGIPA-----------LADT
MAV_2485|M.avium_104 ASGAGR------TELQTLLARWSAAAAILQQGKPVGTVQPQVDVQPPADT
Mb0822c|M.bovis_AF2122/97 GADGEA-------TVHDALSKISGLVRAIGFRDPT---------------
Rv0799c|M.tuberculosis_H37Rv GADGEA-------TVHDALSKISGLVRAIGFRDPT---------------
MMAR_4892|M.marinum_M DAGGEQ-------TVHDALTEISGLVRAIGFRDPT---------------
MUL_0406|M.ulcerans_Agy99 DAGGEQ-------TVHDALTEISGLVRAIGFRDPT---------------
. : * : . : *.
Mflv_4209|M.gilvum_PYR-GCK EPELAARPSRLTVTVGLGAGLF-ERAGLSHRRPDSVTEVPAFSTDRLESR
Mvan_2157|M.vanbaalenii_PYR-1 EPELAQHPSRLTVTVGIGPHVF-DRIGLAHRRPDSVSELPAFSTDRLDRR
TH_1583|M.thermoresistible__bu EPELAHRPARLTVTVGLGPELF-DKIGMSHARPPSARQLPAFTIDRLDPR
MSMEG_6567|M.smegmatis_MC2_155 EPELATRPARLTVTVGLGPGLL-GRLGATVPR--SARDLPEFGPDRLQER
MAB_2270c|M.abscessus_ATCC_199 EPELATTTARLTVSAGLGPSVF-AKTGLADRCPASARDFPAFSTDRLDKR
MAV_2485|M.avium_104 GEADGLSPASLTVTIGLGPSLFGDRFGLAARRPAVFTDLPPLNGDNLDPR
Mb0822c|M.bovis_AF2122/97 --------KHLSVVVSIGSDAW--DRLFAGPRPTELHPFVELTGPRHTAP
Rv0799c|M.tuberculosis_H37Rv --------KHLSVVVSIGSDAW--DRLFAGPRPTELHPFVELTGPRHTAP
MMAR_4892|M.marinum_M --------KHLSVVASIGSDAW--DRLFSGPKPAELHPFVPLTGPRHNAP
MUL_0406|M.ulcerans_Agy99 --------KHLSVVASIGADAW--DRLFSGPKPAELHPFVPLTGPRHNAP
*:* .:*. : . : .
Mflv_4209|M.gilvum_PYR-GCK WCGGDLLLQICADDPLVVAHTARVLLKNVRTMTTQRWQQRGFRSARGSDT
Mvan_2157|M.vanbaalenii_PYR-1 WCGGDILLQICADDRVAVAHAARVLLKNVRTLTVQRWRQDGFRTARGADK
TH_1583|M.thermoresistible__bu WCGGDLFLQICADDPMVVAHTARVLLKNVRTLARPRWRQVGFRTARGADA
MSMEG_6567|M.smegmatis_MC2_155 WSGGDLLLQICGDDPVSIAHATRVLTKNVRAMAVQRWRQAGFRNARGADR
MAB_2270c|M.abscessus_ATCC_199 WCGGDLLLQICADSPLLVAHAARVLLKNVRSLASERWRQTGFRTPRPEDP
MAV_2485|M.avium_104 LHGGDLSVQACADDPQVCYHAVRNLARLGRNIVSPFWAVLGFGRAS-AGP
Mb0822c|M.bovis_AF2122/97 ATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDEVHGFRFFD----
Rv0799c|M.tuberculosis_H37Rv ATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDEVHGFRFFD----
MMAR_4892|M.marinum_M ATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVVDEVHGFRFFD----
MUL_0406|M.ulcerans_Agy99 ATPGDLLLHIRAETMDVCFELAGRILKAMAPAVTVVDEVHGFRFFD----
**: .: .: . . : : . **
Mflv_4209|M.gilvum_PYR-GCK SGATMRNLMGQVDGTVNLRTATDVDRLVWDDGAGQPWFAGGTVLVLRRIR
Mvan_2157|M.vanbaalenii_PYR-1 SGATMRNLMGQVDGTANPREDAELDRYVWDDGSQQPWFAGGTVLVIRRIR
TH_1583|M.thermoresistible__bu PDVTMRNLFGQVDGTVNP-DEADFAELVWMDGRQQPWSAGGSLAVVRRIA
MSMEG_6567|M.smegmatis_MC2_155 QGTSMRNLMGQVDGTVNL-APVEFDELVWLGDEVYPGLAGGTLMVLRRIE
MAB_2270c|M.abscessus_ATCC_199 SGGTMRNLMGQVDGTVNP-TAPELDSLLWHQGEDHEWLKGGTLLVLRRIT
MAV_2485|M.avium_104 GQHTPRNLLGFKDGTRNIASQAEYDRFVWVDDSDQPWMNGGTYQVVRKIR
Mb0822c|M.bovis_AF2122/97 ----NRDLLGFVDGTENPSGPIAIKATTIGDEDRN--FAGSCYVHVQKYV
Rv0799c|M.tuberculosis_H37Rv ----NRDLLGFVDGTENPSGPIAIKATTIGDEDRN--FAGSCYVHVQKYV
MMAR_4892|M.marinum_M ----NRDLLGFVDGTENPGGAIAIGATTVGDEDPD--FAGSCYVHVQKYV
MUL_0406|M.ulcerans_Agy99 ----NRDLLGFVDGTENPGGAIAIGATTVGDEDPD--FAGSCYVHVQKYV
*:*:* *** * *. :::
Mflv_4209|M.gilvum_PYR-GCK TELDSWDELDRTSRELTVGRRLDTGAPLTG--THEFDEPDLDAAEN-GIP
Mvan_2157|M.vanbaalenii_PYR-1 SELDTWDELDRTSKELTLGRRLDTGAPLTG--EGEFDEPDLAATEN-GIP
TH_1583|M.thermoresistible__bu MNLDTWDELGRDARELTVGRRLDNGAPLTG--RHETDEPDLTMLRN-GIP
MSMEG_6567|M.smegmatis_MC2_155 MQLDTWDELDRESKELTVGRTLDSGAPLTG--HRETDEPDFTLARN-GIP
MAB_2270c|M.abscessus_ATCC_199 MNLDGWDQLDRKLRDLVMGRRSDNGAPLSG--EKESDEPDLTMTRG-GIP
MAV_2485|M.avium_104 MLLETWDVDRIGNQQRIFGRTKEEGAPLSG--RHEFDTPDFTAKGADGNP
Mb0822c|M.bovis_AF2122/97 HDMASWESLSVTEQERVIGRTKLDDIELDDNAKPANSHVALNVITDDDGT
Rv0799c|M.tuberculosis_H37Rv HDMASWESLSVTEQERVIGRTKLDDIELDDNAKPANSHVALNVITDDDGT
MMAR_4892|M.marinum_M HDMGSWDSLSVTEQERVIGRTKLEDIELDESTKPANSHIALNVITDEDGV
MUL_0406|M.ulcerans_Agy99 HDMGSWDSLSVTEQERVIGRTKLEDIELDESTKPANSHIALNVITDEDGV
: *: :: .** . * . : .
Mflv_4209|M.gilvum_PYR-GCK VIPPNSHVALARHRHDGERFLRR-AYNYDDPPTDA-TTDAGLIFAAFQRD
Mvan_2157|M.vanbaalenii_PYR-1 VIPPNSHVALARRQSDDERFLRR-GYNYDDPPTVG-TTDAGLIFAAYQRD
TH_1583|M.thermoresistible__bu VIPPNSHVARARHRTPEERFLRR-SYNYDDPPADDRTSDAGLIFVSYQRD
MSMEG_6567|M.smegmatis_MC2_155 VIPPNSHIALARHRHDGERFLRR-PYNYDDPPEPGQTSNTGLIFATYQRD
MAB_2270c|M.abscessus_ATCC_199 VIPATSHVALARHRNPHERFLRR-PYNFDDAPLPGTSSNAGLIFAAYQRD
MAV_2485|M.avium_104 LIDPMSHVGLAARENNDGIMIRRRSYNYTDGLDANGQLNAGLLFISYQKD
Mb0822c|M.bovis_AF2122/97 ERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTEQMLRNMFLGDPAGNTD
Rv0799c|M.tuberculosis_H37Rv ERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTEQMLRNMFLGDPAGNTD
MMAR_4892|M.marinum_M ELKIVRHNMPFGEVGKGEYGTYFIGYSRTPVVTERLLRNMFLGDPPGNTD
MUL_0406|M.ulcerans_Agy99 ELKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTERLLRNMFLGDSPGNTD
* . *. : * . : *
Mflv_4209|M.gilvum_PYR-GCK PAQQFVPVQQRLAASDALNPWITTIGSAVFAILPGAA-DGGYLGQSLLE-
Mvan_2157|M.vanbaalenii_PYR-1 PARQFVPVQRRLAEADAMNPWITTIGSAVFAMLPGVP-EGGYLGQNLLG-
TH_1583|M.thermoresistible__bu IDRQFLPVQQRLADADALNEWTTPIGSAVFVILPGVA-PGGYLGESLLSG
MSMEG_6567|M.smegmatis_MC2_155 IDTQFLPVQQRLAQFDALNQWTTAIGSSVFVILPGVRSPEGYLGQELLAG
MAB_2270c|M.abscessus_ATCC_199 IASQFVPVQQRLAEKDEFNQWNTAVGSAVFVMPPGTT-EDGYLGRSLLG-
MAV_2485|M.avium_104 -PQDFIRLQNRLGAHDLLNEYIRHIGSAIFAVPPAPA-EGHYIAQSLFR-
Mb0822c|M.bovis_AF2122/97 RVLDFSTAVTGGLFFSPTIDFLDHPPPLP--QAATPTLAAGSLSIGSLKG
Rv0799c|M.tuberculosis_H37Rv RVLDFSTAVTGGLFFSPTIDFLDHPPPLP--QAATPTLAAGSLSIGSLKG
MMAR_4892|M.marinum_M RVLDFSTATTGGLFFSPTIDFLDDPPPLPPAPAAVPTTDDGSLSIGSLKG
MUL_0406|M.ulcerans_Agy99 RVLDFSTATTGGLFFSPTIDFLDDPPPLPLAPAAVPTADDGSLSIGSLKG
:* . : . . :. :
Mflv_4209|M.gilvum_PYR-GCK ---
Mvan_2157|M.vanbaalenii_PYR-1 ---
TH_1583|M.thermoresistible__bu ---
MSMEG_6567|M.smegmatis_MC2_155 ---
MAB_2270c|M.abscessus_ATCC_199 ---
MAV_2485|M.avium_104 ---
Mb0822c|M.bovis_AF2122/97 SPR
Rv0799c|M.tuberculosis_H37Rv SPR
MMAR_4892|M.marinum_M ISE
MUL_0406|M.ulcerans_Agy99 TSE