For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TVDRALLLKALGIDLPAELLTIALTHRSYSYENGGVPTNERLEFLGDSVLGLTITEELYHRHPDRSEGDL AKLRASIVNTQALADVGRNLSEHGLGAYLLLGKGEENSGGADKSSILADGVESLLGAIYLEHGAVAAREV ILRLFSDLLDTAPTLGAGLDWKSSLQELTASLALGAPSYHVTSTGPDHDKEFTAVVIIAEREHGTGVGRT KKEAELKAASAAWNALQRAHPDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4192 | rnc | - | 100% (234) | ribonuclease III |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2950c | rnc | 3e-98 | 77.68% (224) | ribonuclease III |
| M. tuberculosis H37Rv | Rv2925c | rnc | 3e-98 | 77.68% (224) | ribonuclease III |
| M. leprae Br4923 | MLBr_01659 | rnc | 5e-98 | 76.21% (227) | ribonuclease III |
| M. abscessus ATCC 19977 | MAB_3256c | rnc | 5e-93 | 73.78% (225) | ribonuclease III |
| M. marinum M | MMAR_1782 | rnc | 6e-99 | 76.99% (226) | ribonuclease III Rnc |
| M. avium 104 | MAV_3783 | rnc | 1e-98 | 76.52% (230) | ribonuclease III |
| M. smegmatis MC2 155 | MSMEG_2418 | rnc | 1e-104 | 81.74% (230) | ribonuclease III |
| M. thermoresistible (build 8) | TH_1224 | rnc | 1e-108 | 83.91% (230) | PROBABLE RIBONUCLEASE III RNC (RNASE III) |
| M. ulcerans Agy99 | MUL_2030 | rnc | 3e-99 | 76.32% (228) | ribonuclease III |
| M. vanbaalenii PYR-1 | Mvan_2171 | rnc | 1e-112 | 89.87% (227) | ribonuclease III |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4192|M.gilvum_PYR-GCK ----MTVDRALLLKALGIDLPAELLTIALTHRSYSYENGGVPTNERLEFL
Mvan_2171|M.vanbaalenii_PYR-1 ----MTVDRALLLEALGVDLPGELLTIALTHRSYSYENGGVPTNERLEFL
MSMEG_2418|M.smegmatis_MC2_155 ----MTDSHAALLEALGVALPAELLTIALTHRSYSYENGGLPTNERLEFL
TH_1224|M.thermoresistible__bu ----VSADRSALLEALGVDLPDELLTIALTHRSYSYEHGGLPTNERLEFL
MLBr_01659|M.leprae_Br4923 ----MTQPRQALLDAFGVDLPDELLSLALTHRSYAYEHGGLPTNERLEFL
MAV_3783|M.avium_104 ----MS-SRQPLLDALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFL
Mb2950c|M.bovis_AF2122/97 ----MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFL
Rv2925c|M.tuberculosis_H37Rv ----MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFL
MMAR_1782|M.marinum_M ------MSRQALLDAVGVELPEELVTLALTHRSYAYENGGLPTNERLEFL
MUL_2030|M.ulcerans_Agy99 ----MSVSRQALLDAVGVELPEELVTLALTHRSYAYENGGLPTNERLEFL
MAB_3256c|M.abscessus_ATCC_199 MSRTPEHRHDDLRAAIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFL
: * *.*: * **:::*******:**:**:*********
Mflv_4192|M.gilvum_PYR-GCK GDSVLGLTITEELYHRHPDRSEGDLAKLRASIVNTQALADVGRNLSEHGL
Mvan_2171|M.vanbaalenii_PYR-1 GDSVLGLTITEELYHRHPDRSEGDLAKLRASIVNTQALADVGRNLTEHGL
MSMEG_2418|M.smegmatis_MC2_155 GDAVLGLTITEELYHRHPDRAEGDLAKLRASIVNTQALADVGRGLTDEGL
TH_1224|M.thermoresistible__bu GDAVLGLTITEELYHRHPDRSEGDLAKLRASIVNTQALADVGRRLSESGL
MLBr_01659|M.leprae_Br4923 GDAVLSLTITDELFHRHPDRSEGDLAKLRASVVNTQALAYVARNLSDGGL
MAV_3783|M.avium_104 GDAVLGLTITDALYHRHPDRTEGDLAKLRASVVNTQALADVARKLCDGGL
Mb2950c|M.bovis_AF2122/97 GDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGL
Rv2925c|M.tuberculosis_H37Rv GDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGL
MMAR_1782|M.marinum_M GDAVLGLTITDELFHRHPERSEGDLAKLRASVVNTQALADVARHLSEHGL
MUL_2030|M.ulcerans_Agy99 GDAVLGLTITDELFHRHPERSEGDLAKLRASVVNTQALADVARHLSDHGL
MAB_3256c|M.abscessus_ATCC_199 GDAVLGLTITETLYHSHPDRSEGDLAKLRASIVNTQALAGVARGLTGDGL
**:**.****: *:* **:*:**********:******* *.* * **
Mflv_4192|M.gilvum_PYR-GCK GAYLLLGKGEENSGGADKSSILADGVESLLGAIYLEHGAVAAREVILRLF
Mvan_2171|M.vanbaalenii_PYR-1 GAYLLLGKGEENSGGADKSSILADGVESLLGAIYLECGGEVAREVILRLF
MSMEG_2418|M.smegmatis_MC2_155 GAHLFLGKGEENSGGADKSSILADGVESLLGAIYLEHGLTVVREVILRLF
TH_1224|M.thermoresistible__bu GAYILLGKGEESSGGADKSSILADGVESLLGAIYIHHGLETSRAVILRLF
MLBr_01659|M.leprae_Br4923 GVYLLLGRGETNTGGADKSSILADGMESLLGAIYLHHGIEVARQVILRLF
MAV_3783|M.avium_104 GAHLLLGRGEANTGGADKSSILADGMESLLGAIYLQHGIDTAREVILRLF
Mb2950c|M.bovis_AF2122/97 GVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLF
Rv2925c|M.tuberculosis_H37Rv GVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLF
MMAR_1782|M.marinum_M GAHMLLGRGEANTGGADKSSILADGMESLLGAIYLHHGMEVAREAILRIF
MUL_2030|M.ulcerans_Agy99 GAHMLLGRGEANTGGADKSSILADGMESLLGAIYLHHGMEVAREAILRIF
MAB_3256c|M.abscessus_ATCC_199 GAHLLLGKGEENTGGRDKSSILADGMESILGAVYLEHGLETARAVVLTLF
*.:::**:** .:** *********:**:***:*:. * * .:* :*
Mflv_4192|M.gilvum_PYR-GCK SDLLDTAPTLGAGLDWKSSLQELTASLALGAPSYHVTSTGPDHDKEFTAV
Mvan_2171|M.vanbaalenii_PYR-1 SSLLDTAPTLGAGLDWKSSLQELTASRGLGAPTYVVTSTGPDHDKEFTAA
MSMEG_2418|M.smegmatis_MC2_155 GELLDTAPTLGAGLDWKSSLQELTAARGLGAPAYVVTSTGPDHDKEFSAT
TH_1224|M.thermoresistible__bu GELLDTAPTLGAGLDWKSSLQELTAARGMGAPSYVVTSTGPDHDKEFTAT
MLBr_01659|M.leprae_Br4923 GTLLDAAPTLGAGLDWKTSLQELTAARGMGVPSYVVTSTGPDHDKEFTAV
MAV_3783|M.avium_104 GALLDAAPTLGAGLDWKTSLQELTAARGMGAPSYLVTSTGPDHDKEFTAV
Mb2950c|M.bovis_AF2122/97 GPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAV
Rv2925c|M.tuberculosis_H37Rv GPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAV
MMAR_1782|M.marinum_M GPLLDAAPTLGAGLDWKTSLQELTASRSLGAPSYAVTSTGPDHHKEFTAV
MUL_2030|M.ulcerans_Agy99 GPLLDAAPTLGAGLDWKTSLQELTASRSLGAPSYAVTSTGPDHHKEFTAV
MAB_3256c|M.abscessus_ATCC_199 GELLETAPKLGAGLDWKTSLQELTAEKGWGAPSYAVTSTGPDHDKEFTAT
. **::**.********:******* . *.*:* ********.***:*.
Mflv_4192|M.gilvum_PYR-GCK VIIAEREHGTGVGRTKKEAELKAASAAWNALQ------RAHPDA------
Mvan_2171|M.vanbaalenii_PYR-1 VMVGDSECGRGVGRTKKEAELKAAAAAWHALT------GDLTSAD-----
MSMEG_2418|M.smegmatis_MC2_155 VVIGEAEYGHGVGRTKKEAELKAAASAYKTLD------ES----------
TH_1224|M.thermoresistible__bu VVIAEQEYGTGTGRTKKEAELKAAAAAWHALD------GA----------
MLBr_01659|M.leprae_Br4923 VVVMDTEYGSGIGHSKKEAEQKAASAAWKALD---VLGGVG--KTSV---
MAV_3783|M.avium_104 VVVADTEYGTGVGRSKKEAEQKAAAATWKALD---VLDPAA--QTSA---
Mb2950c|M.bovis_AF2122/97 VVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE---VLDNAMPGKTSA---
Rv2925c|M.tuberculosis_H37Rv VVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE---VLDNAMPGKTSA---
MMAR_1782|M.marinum_M VVVNNTEYGSGVGRSKKEAEQKAAAAAYQALEGLEVLDGAMPGNSSA---
MUL_2030|M.ulcerans_Agy99 VVVNNTEYGSGVGRSKKEAEQKAAAAAYQALEGLEVLDGAMPGNSSA---
MAB_3256c|M.abscessus_ATCC_199 VMVNDTAHGVGVGRSKKEAEQKAAAEAWNSISGDEPLGGRAEGGDEPLEG
*:: : * * *::***** ***: :::::
Mflv_4192|M.gilvum_PYR-GCK --------
Mvan_2171|M.vanbaalenii_PYR-1 --------
MSMEG_2418|M.smegmatis_MC2_155 --------
TH_1224|M.thermoresistible__bu --------
MLBr_01659|M.leprae_Br4923 --------
MAV_3783|M.avium_104 --------
Mb2950c|M.bovis_AF2122/97 --------
Rv2925c|M.tuberculosis_H37Rv --------
MMAR_1782|M.marinum_M --------
MUL_2030|M.ulcerans_Agy99 --------
MAB_3256c|M.abscessus_ATCC_199 RAEGTVSA