For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ADITAPPSETQLKSLLRALDDLDLPALTALLRPLSAIQVVDVLERLDVHERAVLYRILPKDRALEVFEIL PPSLQGDLVGALQDDAVAALFADMDPDDRVELLDELPATVAGRLMHGLPPDERELTAVVLGYPQRSIGRR MSPEFVSVRPTMTTAEALTRVSAGLDDAETVYMLPVVDDERVLIGVVSLRRLLTAVPGTTIVEVMRPPHW ARATEDAETAARRCADLRVLALPIVDNETRLVGILTVDDALQILETAESEDQARIAGTEPLRRPYLTAPV VSLVRSRVVWLLVLAIGATLTVQVLEVFEATLSEVVTLALFVPLLIGTGGNTGNQAATTVTRALALGDVG PRDLGRVLLRELRVGLSLGLLLGGLAFAVTSLVYDRSIGTVIGLTLVSLCTMAATVGGAMPLIARAIRVD PAVFSNPFISTFVDATGLLIYFTIARAVLGI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4176 | - | - | 100% (452) | magnesium transporter |
| M. gilvum PYR-GCK | Mflv_2208 | - | 3e-18 | 28.46% (260) | MgtE intracellular region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0369 | mgtE | 2e-60 | 34.87% (413) | Mg2+ transporter |
| M. tuberculosis H37Rv | Rv0362 | mgtE | 8e-61 | 35.11% (413) | Mg2+ transport transmembrane protein MgtE |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1524c | - | 9e-19 | 27.62% (239) | hypothetical protein MAB_1524c |
| M. marinum M | MMAR_0670 | mgtE | 2e-60 | 35.11% (413) | Mg2+ transport transmembrane protein MgtE |
| M. avium 104 | MAV_2122 | - | 4e-23 | 31.84% (245) | MgtE intracellular domain-contain protein |
| M. smegmatis MC2 155 | MSMEG_6269 | mgtE | 1e-59 | 35.68% (412) | magnesium transporter |
| M. thermoresistible (build 8) | TH_2821 | - | 0.0 | 78.32% (452) | PUTATIVE magnesium transporter |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0051 | - | 4e-61 | 35.35% (413) | magnesium transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4176|M.gilvum_PYR-GCK ----MADITAPPSETQLKSLLRALDDLDLPALTALLRPLS-AIQVVDVLE
TH_2821|M.thermoresistible__bu ----MTDSRTSSIETEDREILRALDDLDLPALTAAAQRLS-TAQIVAILE
Mb0369|M.bovis_AF2122/97 -----MSIR--PAENSTLDIRHVIGIGTPKAVDLWLDVVTELPDRARELG
Rv0362|M.tuberculosis_H37Rv -----MSIR--PAENSTLDIRHVIGIGTPKAVDLWLDVVTELPDRARELG
MMAR_0670|M.marinum_M -----MSIHYPTVEQSTIDIRQVVGIGTPKAVDLWLDVVTDAPDRVRELA
Mvan_0051|M.vanbaalenii_PYR-1 -----MSSP----TSAAVRLTDILPTAGPGEIQAWLRSVAGPAERRHQVS
MSMEG_6269|M.smegmatis_MC2_155 -----MTTR-----DATIDLRQTVASNTPKAVELWLEVTTDSDERERQLA
MAV_2122|M.avium_104 MGTS----------EDKAPGQPVIHLSQLLRAPVLARSGETVGRVEDVIV
MAB_1524c|M.abscessus_ATCC_199 -----------------MAAVSKVFAARLSGLVVLGPDGESIGRVRDVVI
: :
Mflv_4176|M.gilvum_PYR-GCK RLDVHERAV-LYRILPKDRALEVFEILPPSLQGDLVGALQDDAVAALFAD
TH_2821|M.thermoresistible__bu RLDRKQQAV-LYRVLPKGLALEVFENLDPSLQGDLVGGLKDDAVAALFAQ
Mb0369|M.bovis_AF2122/97 SLSKAELGK-LGPLLDGTNAVELFESIDDKLAAEALHAMDPSLAATFLEA
Rv0362|M.tuberculosis_H37Rv SLSKAELGK-LGPLLDGTNAVELFESIDDKLAAEALHAMDPSLAATFLEA
MMAR_0670|M.marinum_M SLSKAELAK-LGDLLDTTSGVELFESVDDMLAAEALQAMDSAVAASLLDA
Mvan_0051|M.vanbaalenii_PYR-1 RLSRAELRR-LGEVLDGRTAEILLESLDDELAARAVTAMDAAVAATLLAG
MSMEG_6269|M.smegmatis_MC2_155 ALSPAERRG-LGDLLDANTGAELLCSVEIDLAARLLKSMSDSAAARVLQL
MAV_2122|M.avium_104 RLRGADEYP-LVTGIVAGVGGRRVFVGDKSIHEYSADRVLLTKNKIDLRG
MAB_1524c|M.abscessus_ATCC_199 GMGVARKQPRVIGLVVEMLTRRRIFVPMLRVTAIEPGSVTLNTGNVSLRR
: : : . : : :
Mflv_4176|M.gilvum_PYR-GCK MDPDDRVELLD----ELPATVAGRLMHGLP--PDERELTAVVLGYPQRSI
TH_2821|M.thermoresistible__bu LNPDDRVELLD----ELPASVARRLLQGLP--LREREMTADILGYPQGSI
Mb0369|M.bovis_AF2122/97 LDSDHAANILR----EFKEPKREALLTLLP--LERAMVLRGLLSWPEDCA
Rv0362|M.tuberculosis_H37Rv LDSDHAANILR----EFKEPKREALLTLLP--LERAMVLRGLLSWPEDCA
MMAR_0670|M.marinum_M LDSDHAANILR----EFKTAKRDALLASLP--LKRAVVLRGLLSWPEDSA
Mvan_0051|M.vanbaalenii_PYR-1 LDTDHATDILR----EMRAPARDSVLSAMP--ADRSEALRRVLEWPRESA
MSMEG_6269|M.smegmatis_MC2_155 LNSPDAADILR----ELDEHRREAVLGAMP--IERARALLDVLAWPEDSV
MAV_2122|M.avium_104 FERREGEVLLR----TDVLGHRLIDVATVE--LVRAYDIELEQTAAGWMV
MAB_1524c|M.abscessus_ATCC_199 FEQRPSEALVLGQVLDTTVRTDDPELEQFHGVDLTVVDLGLEQTRTRDWV
:: :: : . .
Mflv_4176|M.gilvum_PYR-GCK GRRMSPEFVSVRPTMTTAEALTRV----SAGLDDAETVYMLPVVDDERVL
TH_2821|M.thermoresistible__bu GRRMSPEFVSVRPELTQQQALERV----AAHLDDAETVYTLPVTDNQRVL
Mb0369|M.bovis_AF2122/97 AAHMVPETLTVRPNMTVSQAVASVRERASGLRSDARTTAYVYVTDADSHL
Rv0362|M.tuberculosis_H37Rv AAHMVPETLTVRPNMTVSQAVASVRERASGLRSDARTTAYVYVTDADSHL
MMAR_0670|M.marinum_M AAHMVPETLTVGANMTVLDAIATVREHAAGLRSDSRTTAYVYVIDADSHL
Mvan_0051|M.vanbaalenii_PYR-1 AAHMIPEALAITSELTVADAVEQLRRDAVELRVDAHTSAYIYVTDRDRRL
MSMEG_6269|M.smegmatis_MC2_155 AARMHTDTPSVVPSATIAEAVDQIRDYAAAHP-DGAVGASVCVVDADNTL
MAV_2122|M.avium_104 ARLDTRRPPRLFGLIKHSGGHASRDWKAFEPLIGHARSDAVRRLSDRFGE
MAB_1524c|M.abscessus_ATCC_199 VTRVAVRSPRRLGRRTGVQVTDWSHIQGLTPSTLNLPGQGVAQLMLQFEG
. :
Mflv_4176|M.gilvum_PYR-GCK IGVVSLRRLLTAVPGTTIVEVMRP-PHWARATEDAETAARRCADLRVLAL
TH_2821|M.thermoresistible__bu VGVVSLRELLNAAPDATVAELMKP-AHWVRATEAAELAARRCADLKLLAL
Mb0369|M.bovis_AF2122/97 LGVIAFRALVLANPEQRVRELMGDDLIVVSPLTDKELAAQTIMGHNLMAV
Rv0362|M.tuberculosis_H37Rv LGVIAFRALVLANPEQRVRELMGDDLIVVSPLTDKELAAQTIMGHNLMAV
MMAR_0670|M.marinum_M LGVVAFRALVLADPERLVSELMTEDLIVVSPLTDKELAAQTLMTHNLMAV
Mvan_0051|M.vanbaalenii_PYR-1 LGVAAFRDLVLADPGRHVSELMNDDLLWVSPLTDAEEAAQALEDHNLVAV
MSMEG_6269|M.smegmatis_MC2_155 RGAVRLRELVLAQPQVAIGTLMRDVPVTVTPLTDIEEAAKTLIEHKLDEL
MAV_2122|M.avium_104 LKAAEIADLLEEADKAEGGEILDRVHSDPELEADVFEELDPEKASRLLDE
MAB_1524c|M.abscessus_ATCC_199 MRPVEVADAIRELPPKRRDEVLGAFDDER--LADILQELPEDDQAEVLTK
. : :: .:
Mflv_4176|M.gilvum_PYR-GCK PIVDNETRLVGILTVDDALQILETAESEDQARIAGTEPLRRPYLTAPVVS
TH_2821|M.thermoresistible__bu PVVDNETRLVGILTVDDALRILESAESEDQARIGGAEPLRRPYLTTPVSG
Mb0369|M.bovis_AF2122/97 PVVDADNRLLGIIAEDEAIDIAEEEATEDAERQGGSAPLEVPYLRASPWL
Rv0362|M.tuberculosis_H37Rv PVVDADNRLLGIIAEDEAIDIAEEEATEDAERQGGSAPLEVPYLRASPWL
MMAR_0670|M.marinum_M PVVDGENRLLGIIAEDEALDITQEEATEDAERQGGSAPLEVPYLRASPWL
Mvan_0051|M.vanbaalenii_PYR-1 PVVDADMRLLGILTQSTAAEIAEEEATEDAERQGGSEPLDMPYLRASPWH
MSMEG_6269|M.smegmatis_MC2_155 PVVDAEGRLLGILVEDDAIEAVEREATEDAERQGGSEPLDVPYLRASPWL
MAV_2122|M.avium_104 MPDDEVAALLGRMRADDAADAIVDLR--QSRRRRVLDLMPAPQRTKVITL
MAB_1524c|M.abscessus_ATCC_199 LEDERAADVLEAMDPDDAADLLGELPPAEAES--LLALMDPEDSEPVRRL
: :: : . * : :
Mflv_4176|M.gilvum_PYR-GCK LVRSRVVWLLVLAIGATLTVQVLEVFEATLSE----VVTLALFVPLLIGT
TH_2821|M.thermoresistible__bu LVRSRVVWLLVLAVGATLTVQVLEVFEATLSE----VVTLALFVPLLIGT
Mb0369|M.bovis_AF2122/97 LWRKRAVWLLVLFAAEAYTGSVLRAFSDEMEA----VIALAFFIPLLIGT
Rv0362|M.tuberculosis_H37Rv LWRKRVVWLLVLFAAEAYTGSVLRAFSDEMEA----VIALAFFIPLLIGT
MMAR_0670|M.marinum_M LWRKRVVWLLVLFVAEAYTGSVLRAFSDEMEA----VIALAFFIPLLIGT
Mvan_0051|M.vanbaalenii_PYR-1 LWRKRIGWLLLLFVAEAYTGTVLRHFEEEMEA----VVALAFFIPLLIGT
MSMEG_6269|M.smegmatis_MC2_155 LWRKRIVWLLVLFAAEAYTGTVLRAFEDEMEA----VVALAFFIPLLIGT
MAV_2122|M.avium_104 MGFNPESAGGLMNVDSVSCAASATAAEALALI----ASSHSIQPEALIKV
MAB_1524c|M.abscessus_ATCC_199 LTHSPNTAGGMMTPEPVILTPNTTVAEALARVRDPDLTPALSSLVFVVRP
: . :: . . . ::
Mflv_4176|M.gilvum_PYR-GCK GGNTGNQAATTVTRALALGDVGPRDLGRVLLRELRVGLSLGLLLGGLAFA
TH_2821|M.thermoresistible__bu GGNTGNQAATTVTRALALGDVRPRDLFRVLLREFKVGLALGLILGALAFL
Mb0369|M.bovis_AF2122/97 GGNTGTQIATTLVRAMATGQVRFRDVPAVLAKELSTGVLVGLTMAAAAVV
Rv0362|M.tuberculosis_H37Rv GGNTGTQIATTLVRAMATGQVRFRDVPAVLAKELSTGVLVGLTMAAAAVV
MMAR_0670|M.marinum_M GGNTGTQIATTLVRAMATGQVRFRDVPAVLVKELSTGALVGFTMAVAAVI
Mvan_0051|M.vanbaalenii_PYR-1 GGNTGTQITTTLVRALATGDVRFRDVPSIVAKELSTGMLIALTMALAAVI
MSMEG_6269|M.smegmatis_MC2_155 GGNTGTQITTTLVRAMGTGQIRFRDLPAIVSKEMSTGFLIAVAMAAAALI
MAV_2122|M.avium_104 HVLDEDRRLDGVVSVITLLQVDPSETLERLMDSDPVRVNADADLTDIALL
MAB_1524c|M.abscessus_ATCC_199 PTATPTGRYLGCVHLQRLLREPPYAMVGGILDTDLPYLDAEAPLAEVTRY
. : : :
Mflv_4176|M.gilvum_PYR-GCK -VTSLVYDRSIGTVIGLTLVSLCTMAATVGGAMPLIARAIRVDPAVFSNP
TH_2821|M.thermoresistible__bu -VTSLVYDREIGTVIGLTFVSVCTMAATVGGAMPLLASAVRADPAVFSNP
Mb0369|M.bovis_AF2122/97 RAWTLGVGPQVTLTVALTVAAIVVWSSLVAAVLPPLLKKLRIDPAIVSGP
Rv0362|M.tuberculosis_H37Rv RAWTLGVGPQVTLTVALTVAAIVVWSSLVAAVLPPLLKKLRIDPAIVSGP
MMAR_0670|M.marinum_M RAWTLNVGPQVTVTVAVTVAAIVVWSSLVAAILPPLLKKLRIDPAIVSGP
Mvan_0051|M.vanbaalenii_PYR-1 RAWTLGVGPEVTLCVSLTIGAIVLWSSFIASILPPLLKKCRLDPALVSAP
MSMEG_6269|M.smegmatis_MC2_155 RAWTLGVGPEVTLTVCLTVAAIVLWASLVSSVLPLVLRKLRVDPAVVSAP
MAV_2122|M.avium_104 MADFNLYSIPVVDEQDHLLG-VVTVDDVLEATIPEDWR--RREPAPRPIR
MAB_1524c|M.abscessus_ATCC_199 FAAYNLVCGPVIDREDHLLG-AVTVDDVLDHLMPDGWRAEEPEAVAGGDR
. : . : :* . :..
Mflv_4176|M.gilvum_PYR-GCK FISTFVDATGLLIYFTIARAVLGI----
TH_2821|M.thermoresistible__bu FISTFVDATGLLIYFAIARAVLGI----
Mb0369|M.bovis_AF2122/97 MIATIVDGTGLLIYFLVAHLTLTELHGL
Rv0362|M.tuberculosis_H37Rv MIATIVDGTGLLIYFLVAHLTLTELHGL
MMAR_0670|M.marinum_M LIATIVDGTGLIIYFMIAHLTLTQLQGL
Mvan_0051|M.vanbaalenii_PYR-1 AIATIVDGTGLIIYFWIAHLTLAQLQGL
MSMEG_6269|M.smegmatis_MC2_155 MIATVVDGTGLMIYFWIAHLTLPQLAGL
MAV_2122|M.avium_104 EITTAEDRP-------LPGGNAP-----
MAB_1524c|M.abscessus_ATCC_199 P---------------------------