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GTSEDKAPGQPVIHLSQLLRAPVLARSGETVGRVEDVIVRLRGADEYPLVTGIVAGVGGRRVFVGDKSIH EYSADRVLLTKNKIDLRGFERREGEVLLRTDVLGHRLIDVATVELVRAYDIELEQTAAGWMVARLDTRRP PRLFGLIKHSGGHASRDWKAFEPLIGHARSDAVRRLSDRFGELKAAEIADLLEEADKAEGGEILDRVHSD PELEADVFEELDPEKASRLLDEMPDDEVAALLGRMRADDAADAIVDLRQSRRRRVLDLMPAPQRTKVITL MGFNPESAGGLMNVDSVSCAASATAAEALALIASSHSIQPEALIKVHVLDEDRRLDGVVSVITLLQVDPS ETLERLMDSDPVRVNADADLTDIALLMADFNLYSIPVVDEQDHLLGVVTVDDVLEATIPEDWRRREPAPR PIREITTAEDRPLPGGNAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2122 | - | - | 100% (440) | MgtE intracellular domain-contain protein |
| M. avium 104 | MAV_1371 | - | 4e-40 | 30.31% (419) | Mg/Co/Ni transporter MgtE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1264c | - | 6e-40 | 30.73% (436) | hypothetical protein Mb1264c |
| M. gilvum PYR-GCK | Mflv_2208 | - | 2e-40 | 30.90% (424) | MgtE intracellular region |
| M. tuberculosis H37Rv | Rv1232c | - | 4e-39 | 30.73% (436) | hypothetical protein Rv1232c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2717c | - | 1e-158 | 67.14% (423) | hypothetical protein MAB_2717c |
| M. marinum M | MMAR_4209 | - | 6e-41 | 30.86% (431) | transport transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_5065 | - | 2e-35 | 29.70% (431) | Mg/Co/Ni transporter MgtE |
| M. thermoresistible (build 8) | TH_2063 | - | 1e-40 | 30.65% (434) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4488 | - | 1e-41 | 31.51% (438) | MgtE intracellular region |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5065|M.smegmatis_MC2_155 MAAVN-------RVYAARLAGLVVLGPDGESIGRVRDVVISISIVRQQPR
TH_2063|M.thermoresistible__bu MASVN-------RVYAARLAGMVVLGPDGESIGRVRDVVISISIVRQQPR
Mflv_2208|M.gilvum_PYR-GCK MASVN-------RVYAARLAGMVVLGPDGESIGRVRDVVIGISVVRHQPR
Mvan_4488|M.vanbaalenii_PYR-1 MVSVN-------RVYAARLAGMVVLGPDGESIGRVRDVVIGISLVRHQPR
Mb1264c|M.bovis_AF2122/97 MGSVN-------RVYLARLSRMSVLGPLGESFGRVRDVVISISIVRQQPR
Rv1232c|M.tuberculosis_H37Rv MGSVN-------RVYLARLSRMSVLGPLGESFGRVRDVVISISIVRQQPR
MMAR_4209|M.marinum_M MGSVN-------RVYVARLSRMMVLGPFGETFGRVRDVVISISIVRQQPR
MAV_2122|M.avium_104 MGTSEDKAPGQPVIHLSQLLRAPVLARSGETVGRVEDVIVRLRGADEYPL
MAB_2717c|M.abscessus_ATCC_199 MATSNTAATPR-VIQFSDLLKAPVVARSGETIGRLEDVIVRLRGSDRYPL
* : : : : * *:. **:.**:.**:: : . *
MSMEG_5065|M.smegmatis_MC2_155 VIGLVVELLTRRRIFVPILRVTAIEPGAVTLATGSVSLRKFVQRPGEVLV
TH_2063|M.thermoresistible__bu VLGLVVELLTRRRIFVPILRVTAIEPGAVTLNTANVSLRRFAQRPGEVLV
Mflv_2208|M.gilvum_PYR-GCK VLGLVIELLSRRRIFVPILRVTAIEPGAVTLSTGNVSLRRFSQRPGEVLV
Mvan_4488|M.vanbaalenii_PYR-1 VLGLVIELMTRRRIFVPILRVTAIEPGAVTLSTGNVSLRRFSQRPGEVLV
Mb1264c|M.bovis_AF2122/97 VLGLVVDLATRRKIFIPILRVAAIEPHAVTLSTGNVSLHRFEQRPGEALA
Rv1232c|M.tuberculosis_H37Rv VLGLVVDLATRRKIFIPILRVAAIEPHAVTLSTGNVSLHRFEQRPGEALA
MMAR_4209|M.marinum_M VLGLVVDLATRRSIFIPMLRVAAIEPNAVTLSTASVSLRHFEQRPGEVLA
MAV_2122|M.avium_104 VTGIVAGVGGRR-VFVGDKSIHEYSADRVLLTKNKIDLRGFERREGEVLL
MAB_2717c|M.abscessus_ATCC_199 VTGYVVDMGGRT-VFISADVVSVVAPDRIELSKNKVDLRGFERRDGEYLL
* * * : * :*: : . : * . .:.*: * :* ** *
MSMEG_5065|M.smegmatis_MC2_155 LGQVLETRVRVEDPDLPELAGVDVVVVDLGIEQTRTRDWVVTRFAVRQ-Q
TH_2063|M.thermoresistible__bu LGQVVETRVRINDPDLPDLAGVDLVVVDLGIEQSRTRDWLVTRVAVRRPH
Mflv_2208|M.gilvum_PYR-GCK LGQVVETRVRVDDPDLPALAGLDVVVVDLGIEQTRTRDWVVTRVAVRP-Q
Mvan_4488|M.vanbaalenii_PYR-1 LGQVIETRVRVDDPDLPQLAGVDVVVVDLAIEQTRARDWMVTKVAVRQ-Q
Mb1264c|M.bovis_AF2122/97 LGQVLDTLVKVNDPALPELAGVDVVVTDLGVEQTRSRDWMVTRVAVRT-Q
Rv1232c|M.tuberculosis_H37Rv LGQVLDTLVKVNDPALPELAGVDVVVTDLGVEQTRSRDWMVTRVAVRT-Q
MMAR_4209|M.marinum_M IGQVLDTPVRVNDPDLPELANADIVITDLGIEQTRTRDWMVTRVAVRS-P
MAV_2122|M.avium_104 RTDVLGHR-------LIDVATVELVRAYDIELEQTAAGWMVARLDTRRPP
MAB_2717c|M.abscessus_ATCC_199 DEDVLDHR-------FIDVDNAELVHAYDIELQETAEGWILARLDTRRPA
:*: : : ::* . : : .*::::. .*
MSMEG_5065|M.smegmatis_MC2_155 RRLGRRSNVYVVEWQN-VHGLTPSGLAMPDQGVASLLEQFEGQRPVEVAE
TH_2063|M.thermoresistible__bu RRLTRRSNIYVTDWQYVVQGLTPSGLALPDQGVAQLLEQFEGQRPVEVAD
Mflv_2208|M.gilvum_PYR-GCK RRLGRRSNVYTTEWDH-VQGLTPAGLAMPDQGVAQLLEQFEGQRPVEVAD
Mvan_4488|M.vanbaalenii_PYR-1 RRLGRRSNVYTVEWQN-VQGLTPSGLAMPDQGVAQLLEQFEGQRAVEVAD
Mb1264c|M.bovis_AF2122/97 RRLRRRGPVHVVDWHN-VAGLTPSALAMPGQDVAQLLDQFEGWKAVDVAD
Rv1232c|M.tuberculosis_H37Rv RRLRRRCPVHVVDWHN-VAGLTPSALAMPGQDVAQLLDQFEGWKAVDVAD
MMAR_4209|M.marinum_M RRLGRRGPLHVVDWQN-VRGLTPSALAMPDQDVAQLLDQFEGRRAVDVAD
MAV_2122|M.avium_104 RLFGLIKHSGGHASRD-WKAFEPLIGHARSDAVRRLSDRFGELKAAEIAD
MAB_2717c|M.abscessus_ATCC_199 RFFGLIKAGAGQAGRD-WKAFEPMIGHGGSLLARRVGGRVNTLKPAEIAD
* : .: * . . : :. :..::*:
MSMEG_5065|M.smegmatis_MC2_155 ALRELPPKRRYELFRAFDD--DRLADVLAELPEDEQADVLRGLNTERAAL
TH_2063|M.thermoresistible__bu ALRELPPKRRFEVIAAFDD--DRLADVLQELTAAEQTQVLRQLKTDRAAT
Mflv_2208|M.gilvum_PYR-GCK AIRELPGKRRNEVVNALDD--ERLADVLQELPEEEQVELLRQLKTDRAAD
Mvan_4488|M.vanbaalenii_PYR-1 AIRELPNKRRYEVVNALDD--ERLADVLQELPEDQQVALLRQLKTDRAAD
Mb1264c|M.bovis_AF2122/97 AIRGLPPKRRHEVFKALHD--KRLADVLQELPELDQAEVLSQLGTERAAD
Rv1232c|M.tuberculosis_H37Rv AIRGLPPKRRHEVFKALHD--KRLADVLQELPELDQAEVLSQLGTERAAD
MMAR_4209|M.marinum_M AIRGLPSKRRYEVFKALDD--ERLADILQELPELDQAEVLSQLGTERAAD
MAV_2122|M.avium_104 LLEEADKAEGGEILDRVHSDPELEADVFEELDPEKASRLLDEMPDDEVAA
MAB_2717c|M.abscessus_ATCC_199 LLEEATKEEGGEILDRVRDNPELEADVFEELDSEKAGKLFEDMSDGDVAA
:. . *:. . . . **:: ** . :: : .*
MSMEG_5065|M.smegmatis_MC2_155 VLEAMDPDDAADLLGAMTPADAEVLLGRMDPEDSEDVRRLLAHSPDTAGG
TH_2063|M.thermoresistible__bu VLEAMDPDDAADLLGALAPTDAEALLRRMDPEDSEDVRRLLSHSPNTAGG
Mflv_2208|M.gilvum_PYR-GCK VLEAMDPDDAADLLGTMTPADAEQLLRRMDPEDSEDVRRLLSHSPNTAGG
Mvan_4488|M.vanbaalenii_PYR-1 VLEAMDPDDAADLLGTMTPADAEQFLRRMDPEDSEDVRRLLSHSPDTAGG
Mb1264c|M.bovis_AF2122/97 VLEEMDPDDAADLLAVLNPTEAELLLTRMDPGDSGQVRRLLTHSPDTAGG
Rv1232c|M.tuberculosis_H37Rv VLEEMDPDDAADLLAVLNPTEAELLLTRMDPGDSGQVRRLLTHSPDTAGG
MMAR_4209|M.marinum_M VLEEMDPDDAADLLGVLNPTDAEVLLTRMDPDDSDSVRRLLQHSPDTAGG
MAV_2122|M.avium_104 LLGRMRADDAADAIVDLRQSRRRRVLDLMPAPQRTKVITLMGFNPESAGG
MAB_2717c|M.abscessus_ATCC_199 LLGRMRADDAADAIFDLRQSRRRAVLELMPAPQRTKVVTLMGFSPESAGG
:* * .***** : : : . .* * . : .* *: ..*::***
MSMEG_5065|M.smegmatis_MC2_155 LMTSEPVVLAPDTTVAEALARVRDPDLTPALASLAFVARPPTATPTGHYL
TH_2063|M.thermoresistible__bu LMTSEPVVLSPGTTVAEALARVRDPDLTPAVASVAFVTRPPTATPTGHYL
Mflv_2208|M.gilvum_PYR-GCK LMTSEPVVLAPDTTVAEALARVRDPDLTPALASLVFVVRPPTATPTGHYL
Mvan_4488|M.vanbaalenii_PYR-1 LMTSEPVVLAPDTTVAEALARVRDPDLTPALASVVFVVRPPTSTPTGRYL
Mb1264c|M.bovis_AF2122/97 LMTSDPVVLTPDTSIAEALARVRDPDLTPALASMVFVARPPTATPTGHYL
Rv1232c|M.tuberculosis_H37Rv LMTSDPVVLTPDTSIAEALARVRDPDLTPALASMVFVARPPTATPTGHYL
MMAR_4209|M.marinum_M LMTSNPVVLTPDTSVAEALARVRDPDLTPALSSMVFVARPPTATPTGHYV
MAV_2122|M.avium_104 LMNVDSVSCAASATAAEALALIASSHSIQPEALIKVHVLD----EDRRLD
MAB_2717c|M.abscessus_ATCC_199 LMNVDIVSCVLGSTVGAALGAISAAKSLQPEALLKVHVLA----DNGELV
**. : * .:: . **. : .. . : : . . .
MSMEG_5065|M.smegmatis_MC2_155 GCVHLQRLLREPPATLVSGIVDNDLPTLSPEDSLAAVTRYFAAYNLVCGP
TH_2063|M.thermoresistible__bu GCVHLQRLLREPPAALVSGILDADLPVLHPEESLAAVTRYFAAYNLVCGP
Mflv_2208|M.gilvum_PYR-GCK GCVHLQRLLREPPATLVSGIIDSDLPQLAPEDSLGALTRYFAAYNLVCGP
Mvan_4488|M.vanbaalenii_PYR-1 GCVHLQRLLREPPAGLVSGIVDTDLPSLRPEDSLGALTRYFAAYNLVCGP
Mb1264c|M.bovis_AF2122/97 GCVHLQRLLRDPPAELVGGVVDTDLLTLTPETPLAAVTRYFAAYNLVCGP
Rv1232c|M.tuberculosis_H37Rv GCVHLQRLLRDPPAELVGGVVDTDLLTLTPETPLAAVTRYFAAYNLVCGP
MMAR_4209|M.marinum_M GYVHLQRLLREPPAELVGGIVDTDLLTLTPETPLAAVTRYFAAYNLVCGP
MAV_2122|M.avium_104 GVVSVITLLQVDPSETLERLMDSDPVRVNADADLTDIALLMADFNLYSIP
MAB_2717c|M.abscessus_ATCC_199 GVVSVIRLLQADGDAAVESVMDDDPVRVAPQADLTDVALLMADYNLALIP
* * : **: : ::* * : .: * :: :* :** *
MSMEG_5065|M.smegmatis_MC2_155 VVDSQNHLVGAVSVDDVLDHLLPDDWRETD-EPELRVSGS----------
TH_2063|M.thermoresistible__bu VVDEQNHLLGAVSVDDVLDHLLPDDWRQQE-EPELTDAEGLT--------
Mflv_2208|M.gilvum_PYR-GCK VVDEENHLLGAVSVDDVLDHLLPDNWRERESEPLIVSVEGRHE-------
Mvan_4488|M.vanbaalenii_PYR-1 VVDEESHLLGAVSVDDVLDHLLPDDWRDREAEPVIVTAEKAT--------
Mb1264c|M.bovis_AF2122/97 VVDDENHLLGAVTVDDLLDHLLPHDWRVDMPELDPSGAPDRPGGPR----
Rv1232c|M.tuberculosis_H37Rv VVDDENHLLGAVTVDDLLDHLLPHDWRVDMPELDPSGAPDRPGGPR----
MMAR_4209|M.marinum_M VVDDQNHLLGAVTVDDLLDHLLPHDWRVDVQQLDPAGRPARSGGAL----
MAV_2122|M.avium_104 VVDEQDHLLGVVTVDDVLEATIPEDWRRREPAPRPIREITTAEDRPLPGG
MAB_2717c|M.abscessus_ATCC_199 VVDEGDRVLGVVTYDDVLAALIPQDWRRREPAPRPVRQAASN-----PDG
***. .:::*.*: **:* :*.:**
MSMEG_5065|M.smegmatis_MC2_155 ---
TH_2063|M.thermoresistible__bu ---
Mflv_2208|M.gilvum_PYR-GCK ---
Mvan_4488|M.vanbaalenii_PYR-1 ---
Mb1264c|M.bovis_AF2122/97 ---
Rv1232c|M.tuberculosis_H37Rv ---
MMAR_4209|M.marinum_M ---
MAV_2122|M.avium_104 NAP
MAB_2717c|M.abscessus_ATCC_199 VAP