For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_4138 (-)

annotation: DNA protecting protein DprA
coordinates: 4390170 - 4391336
length: 388

DVMDEATRRAWAYVSRVAEPPHRLLSELVATEGVVAAAERIRRRDIDPKLLRATEARYDLDCARDDLEVL
DRMGGRLLTDTDEEWPHLAFAAFRGVDHARRPQGRPPLVLWVLGPLLLCDVAERSAAIVGTRAATSYGEY
VAADLAAGLVERDFAVVSGGAYGIDGAAHRATLAADGDTVAVLAAGLDVPYPAGHSALLHRVGKHGLLVS
EYPPGTRPTRRQFLTRNRLVAALGRATVVIEAGVRSGAANTAGWADALGRQVCAVPGPITSASSVGCHEL
LKRDGVTLVTRAADIVELVGRSGEFAPDLDRPTTGLDDLDDVELAVFDALPGRGMSTVDEIAVTAGLPAT
DVLGPLTMLNVRGLAVQENGGWKLAKRWPPAAQLPLV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4138--100% (388)DNA protecting protein DprA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2920c-1e-12863.10% (374) hypothetical protein Mb2920c
M. tuberculosis H37RvRv2896c-1e-12862.83% (374) hypothetical protein Rv2896c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3212c-1e-11356.83% (366) hypothetical protein MAB_3212c
M. marinum MMMAR_1814-1e-12662.60% (377) hypothetical protein MMAR_1814
M. avium 104MAV_3749-1e-12159.74% (380) smf family protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_0843-1e-13864.53% (375) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_2062-1e-12561.42% (381) hypothetical protein MUL_2062
M. vanbaalenii PYR-1Mvan_2204-1e-13163.37% (374) transcriptional regulator, TrmB

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4138|M.gilvum_PYR-GCK          MDVMDEATRRAWAYVSRVAEPPHRLLSELVATEGVVAAAERIRRRDIDPK
TH_0843|M.thermoresistible__bu      ---MTDQTARAWAYLARVAEPPCPAVAGLVDRVGPVDAAELIRRGDVDDR
Mb2920c|M.bovis_AF2122/97           --MIDP-TARAWAYLSRVAEPPCAQLAALVRCVGPVEAADRVRRGQVGNE
Rv2896c|M.tuberculosis_H37Rv        --MIDP-TARAWAYLSRVAEPPCAQLAALVRCVGPVEAADRVRRGQVGNE
MMAR_1814|M.marinum_M               MSASDG-ALRAWGYLSRVAEPPCAELAALVQRVGPVEAAERIRRGQVDGE
MUL_2062|M.ulcerans_Agy99           MSASDS-ALRAWGYLSRVAEPPCAELAALVQRVGPVEAAERIRRGQVDGE
MAV_3749|M.avium_104                MTAADPRALRAWAYLSRVAEPPCPGLGALVRRVGPVEAAERVRRAAVDDA
Mvan_2204|M.vanbaalenii_PYR-1       ---MDETTRRAWAYLSRVAEPPCAALAALVAEAGAVDAAERVRRGAVSAD
MAB_3212c|M.abscessus_ATCC_199      ---MSS-ATADWAYLSRVSEAPSAELAAMVSVFGVRETAARVRRLDVPDQ
                                           :   *.*::**:*.*   :. :*   *   :*  :**  :   

Mflv_4138|M.gilvum_PYR-GCK          LLRATEARYDLDCARDDLEVLDRMGGRLLTDTDEEWPHLAFAAFRGVDHA
TH_0843|M.thermoresistible__bu      LAKRTEARRDWDCAATDLELMARLGGRLVTAADPDWPVLAFTAFGGADRS
Mb2920c|M.bovis_AF2122/97           LAQHTGARRGIDRAADDLELLMRRGGRLITPDDDEWPVLAFAAFSGAGAR
Rv2896c|M.tuberculosis_H37Rv        LAQHTGARREIDRAADDLELLMRRGGRLITPDDDEWPVLAFAAFSGAGAR
MMAR_1814|M.marinum_M               LARLTRARCEIDRAAADLEQLARRGGRLITPDDDEWPVVAFTAFSGSAIR
MUL_2062|M.ulcerans_Agy99           LARLTRARCEIDRAAADLEQRARRGGRLITPDDDEWPVVAFTAFSGSAIR
MAV_3749|M.avium_104                LAKHTEARREIDRAAADLELIARRGGRLVTPDDDEWPVLAFAAFGAATPR
Mvan_2204|M.vanbaalenii_PYR-1       LRARVESRRDIDCAAADLDLIDRRGGRLITPDDDDWPTWVLNDFGRKDPP
MAB_3212c|M.abscessus_ATCC_199      VRAVVRARHDVDRSREDLEILSRLQGRLVTPDDAEWPHWQFQAFASVDTK
                                    :   . :*   * :  **:   *  ***:*  * :**   :  *      

Mflv_4138|M.gilvum_PYR-GCK          RRPQG--RPPLVLWVLGPLLLCDVAERSAAIVGTRAATSYGEYVAADLAA
TH_0843|M.thermoresistible__bu      HRPDG--HPPLALWVIGELTLDAVAGRSAAIVGTRAASSYGEHVAADLAT
Mb2920c|M.bovis_AF2122/97           ARPCG--HSPLVLWALGPARLDEVAPRAAAVVGTRAATAYGEHVAADLAA
Rv2896c|M.tuberculosis_H37Rv        ARPCG--HSPLVLWALGPARLDEVAPRAAAVVGTRAATAYGEHVAADLAA
MMAR_1814|M.marinum_M               AKGNG--GAPMALWVQGPARLDQVVQRAAALVGTRAATAYGEHMAADLAA
MUL_2062|M.ulcerans_Agy99           AKGNG--GAPMALWVQGPARLDQVVQRTAALVGTRAATAYGEHMAADLAA
MAV_3749|M.avium_104                PPGTAPMLAPLVLWAQGPARLDEVAHRAAAVVGTRAATAYGEQVAGDLVA
Mvan_2204|M.vanbaalenii_PYR-1       VAEDY---PPLVLWVLGQENLADVAARAAAIVGTRACTAYGEHVTADLVA
MAB_3212c|M.abscessus_ATCC_199      RMPNG--RMPLALWVVGERSLAEVTSRAAALVGTRACSGYGEHVTAELAA
                                             *:.**. *   *  *. *:**:*****.:.*** ::.:*.:

Mflv_4138|M.gilvum_PYR-GCK          GLVERDFAVVSGGAYGIDGAAHRATLAADGDTVAVLAAGLDVPYPAGHSA
TH_0843|M.thermoresistible__bu      GLAARDVAVISGGAYGIDGVAHRAALAAEGLTVAVLAGGVDVRYPAGHAG
Mb2920c|M.bovis_AF2122/97           GLAERDVAVVSGGAYGIDGAAHRAALDSEGITVAVLAGGFDIPYPAGHSA
Rv2896c|M.tuberculosis_H37Rv        GLAERDVSVVSGGAYGIDGAAHRAALDSEGITVAVLAGGFDIPYPAGHSA
MMAR_1814|M.marinum_M               GLVERDVAVISGGAYGIDGAAHRAVLIAEGTTVAVLAGGIDIPYPTGHSA
MUL_2062|M.ulcerans_Agy99           GLVERDVAVISGGAYGIDGAAHRAVLIAEGTTVAVLAGGIDIPYPTGHSA
MAV_3749|M.avium_104                GLVQRDVAVVSGGAYGIDGAAHRAALDCDGVTVAVLAGGLDVAYPSGHSA
Mvan_2204|M.vanbaalenii_PYR-1       GLVERDVAVVSGGAFGIDGAAHRAALASDGVTVAVLAGGIDVPYPAGHSA
MAB_3212c|M.abscessus_ATCC_199      GLTAREVAVVSGAAFGIDGVAHRATLACDGVTVAVLAGGVDVPYPAGHSG
                                    **. *:.:*:**.*:****.****.* .:* ******.*.*: **:**:.

Mflv_4138|M.gilvum_PYR-GCK          LLHRVGKHGLLVSEYPPGTRPTRRQFLTRNRLVAALGRATVVIEAGVRSG
TH_0843|M.thermoresistible__bu      LLQRIAEHGLLISEYPPGTRPSRRRFLTRNRLVAALSGATVVVEAGIRSG
Mb2920c|M.bovis_AF2122/97           LLHRIAQHGVLFTEYPPGVRPARHRFLTRNRLVAAVARAAVVVEAGLRSG
Rv2896c|M.tuberculosis_H37Rv        LLHRIAQHGVLFTEYPPGVRPARHRFLTRNRLVAAVARAAVVVEAGLRSG
MMAR_1814|M.marinum_M               LLHRIGQHGLLVTEYPPGVRPARHRFLTRNRLVAALGGAAVVVEAGLRSG
MUL_2062|M.ulcerans_Agy99           LLHWIGQHGLLVTEYPPGVRPARHRFLTRNRLVAALGGAAVVVEAGLRSG
MAV_3749|M.avium_104                LLHRIGQHGLLFTEYAPGVRPARYRFLTRNRLVAAMAGATVVVEAGLRSG
Mvan_2204|M.vanbaalenii_PYR-1       LLHRVSGSGLLVSEYPPGVRPARYRFLTRNRLVAALSGATVVVEAGLRSG
MAB_3212c|M.abscessus_ATCC_199      LLYRIARHGLVVSEYPPGVRPARHRFLTRNRLVAALSGATVVVEAGARSG
                                    **  :.  *::.:**.**.**:* :**********:. *:**:*** ***

Mflv_4138|M.gilvum_PYR-GCK          AANTAGWADALGRQVCAVPGPITSASSVGCHELLKRDGVTLVTRAADIVE
TH_0843|M.thermoresistible__bu      AANTAAWAETLGRPVGAVPGPVTSATSVGCHVLLRERAATVITRAEEVVE
Mb2920c|M.bovis_AF2122/97           AANTAAWARALGRVVAAVPGPVTSSASAGCHTLLR-HGAELVTRADDIVE
Rv2896c|M.tuberculosis_H37Rv        AANTAAWARALGRVVAAVPGPVTSSASAGCHTLLR-HGAELVTRADDIVE
MMAR_1814|M.marinum_M               AANTAAWARALGRIVAAVPGPATSSASAGCHVLLR-NGAQLITRADEIVE
MUL_2062|M.ulcerans_Agy99           AANTAAWARALGRIVAAVPGPATSSASAGCHVLLR-NGAQLITRADEIVE
MAV_3749|M.avium_104                AANTAAWARALGRVVAAVPGPVTSSASAGCHALLR-NGAELITRAEHVVE
Mvan_2204|M.vanbaalenii_PYR-1       AANTAGWSRSLGRGVCAVPGPVTSAASAGCHELLRREGTVLVTRAQEVVE
MAB_3212c|M.abscessus_ATCC_199      AANTAAWARILGRPVGAVPGPITSAASVGTHVEIAERGAQLVVCAQDVVA
                                    *****.*:  *** * ***** **::*.* *  :   .. ::. * .:* 

Mflv_4138|M.gilvum_PYR-GCK          LVGRSGEFAPDLDRPTTGLDDLDDVELAVFDALPGRGMSTVDEIAVTAGL
TH_0843|M.thermoresistible__bu      LVGRCGELAPDLPRPSSPLDDLTDAELLVYEALPARAARTVDQIAVACGM
Mb2920c|M.bovis_AF2122/97           FVGHIGELAGDEPRPGAALDVLSEAERQVYEALPGRGAATIDEIAVGSGL
Rv2896c|M.tuberculosis_H37Rv        FVGHIGELAGDEPRPGAALDVLSEAERQVYEALPGRGAATIDEIAVGSGL
MMAR_1814|M.marinum_M               LVGRIGELSLEQSRPTSVLDGLSQSESQVYEALPGRGAMSVDEIAVASGL
MUL_2062|M.ulcerans_Agy99           LVGRIGELSLEQSRPTSVLDGLSQSESQVYEALPGRGAMSVDEIAVASGL
MAV_3749|M.avium_104                LIGHIGELAAEEPHPVTPLDGLGEAERRVYEALPGRGAATVEQLAAGCGL
Mvan_2204|M.vanbaalenii_PYR-1       VMGRIGELADELEHPVRPLDGLSGVQRLVYEALPARGARTVDEIGRDSGV
MAB_3212c|M.abscessus_ATCC_199      LAGRLGEFTAAPDRPGSVIDGLGDDEKRVYEALPGRGSTTVRELVRESGL
                                    . *: **::    :*   :* *   :  *::***.*.  :: ::   .*:

Mflv_4138|M.gilvum_PYR-GCK          PATDVLGPLTMLNVRGLAVQENGGWKLAKRWPPAAQLPLV-----
TH_0843|M.thermoresistible__bu      PPQEVLAPLSMLELAGLVVRRDGRWQLARR---------------
Mb2920c|M.bovis_AF2122/97           LPAQVLGPLAILEVAGLAECRDGRWRILRAGAGQAAAKGAAARLV
Rv2896c|M.tuberculosis_H37Rv        LPAQVLGPLAILEVAGLAECRDGRWRILRAGAGQAAAKGAAARLV
MMAR_1814|M.marinum_M               VAEQVMGRLAILEVAGLAERDGGRWRLVRAGRARPAAEGVRARLV
MUL_2062|M.ulcerans_Agy99           VAEQVMGRLAILEVAGLAERDGGRWRLVRAGRSRPAAEGVRARLV
MAV_3749|M.avium_104                LPEQALGPLAMLELAGLVRRQDGRWRIVRTAAGPAPPPA------
Mvan_2204|M.vanbaalenii_PYR-1       PAAQVLGPLTILEIDGLVERHEGKWRLARPARRAG----------
MAB_3212c|M.abscessus_ATCC_199      SVGRVQGALAILELEQLVIDVAGDWKLRRTNMVR-----------
                                        . . *::*::  *.    * *:: :