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SRRQGITPAVYNTVMDRGNGLCRYCEFPASEIDHIVPVARGGGNDLANLVPACRECNSEKRDLLPEEWAD KRRADGKPWPIPTFIQRVKFLCHWYLPASQRHKGRFTLREPEKFRGLVVAARDCAELDGGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3897 | - | - | 100% (133) | HNH endonuclease |
| M. gilvum PYR-GCK | Mflv_2573 | - | 8e-08 | 38.33% (60) | HNH endonuclease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2496c | - | 5e-08 | 38.81% (67) | hypothetical protein Mb2496c |
| M. tuberculosis H37Rv | Rv2469c | - | 5e-08 | 38.81% (67) | hypothetical protein Rv2469c |
| M. leprae Br4923 | MLBr_01254 | - | 7e-08 | 37.31% (67) | hypothetical protein MLBr_01254 |
| M. abscessus ATCC 19977 | MAB_1567 | - | 5e-07 | 36.67% (60) | HNH endonuclease precursor |
| M. marinum M | MMAR_3820 | - | 2e-07 | 32.56% (86) | hypothetical protein MMAR_3820 |
| M. avium 104 | MAV_1702 | - | 1e-07 | 37.31% (67) | HNH endonuclease family protein |
| M. smegmatis MC2 155 | MSMEG_4694 | - | 2e-07 | 40.00% (60) | HNH endonuclease family protein |
| M. thermoresistible (build 8) | TH_0922 | - | 1e-08 | 39.44% (71) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3745 | - | 1e-07 | 32.56% (86) | hypothetical protein MUL_3745 |
| M. vanbaalenii PYR-1 | Mvan_4063 | - | 4e-08 | 38.33% (60) | HNH endonuclease |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2496c|M.bovis_AF2122/97 MAHGKKRRGHRSSGVAAGVTG--PASCLHGVHSHRLASGVETHPPNRHES
Rv2469c|M.tuberculosis_H37Rv MAHGKKRRGHRSSGVAAGVTG--PASCLHSVHSHRLASGVETHPPNRHES
MMAR_3820|M.marinum_M MAQGKKRRGHRNHGAAASMTG--TASCLH---------SVDTHPPNRHET
MUL_3745|M.ulcerans_Agy99 MAQGKKRRGHRNHGAAANMTG--TASCLH---------SVDTHPPNRHET
MAV_1702|M.avium_104 MAQGKKRRRHRSQVAAAGLTGPPTASSLH---------SVETHPPTRPDS
MLBr_01254|M.leprae_Br4923 MVQRKNRRSHRSSGAAANLIRAANPSSLH---------NVDIHPSTCYES
MAB_1567|M.abscessus_ATCC_1997 MPPQQSN-----------------------------------------DA
Mvan_4063|M.vanbaalenii_PYR-1 MAQRKNGRGHRHHRTAAGTSGSTSATTSRALHS---VAPSVDTLTPAPQD
MSMEG_4694|M.smegmatis_MC2_155 MPNRPLHS--------------------------------VEPLASAEPD
TH_0922|M.thermoresistible__bu --------------------------------------------------
Mflv_3897|M.gilvum_PYR-GCK MSRRQGITP--------------------------------------AVY
Mb2496c|M.bovis_AF2122/97 ASIWNRRRVLLLNSTYEPLTALSMRRAIVMVICGKADVVHEDPSGPVIHS
Rv2469c|M.tuberculosis_H37Rv ASIWNRRRVLLLNSTYEPLTALSMRRAIVMVICGKADVVHEDPSGPVIHS
MMAR_3820|M.marinum_M ASIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHS
MUL_3745|M.ulcerans_Agy99 ASIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHDDPAGPVIHS
MAV_1702|M.avium_104 TSIWSRRRVLLLNSTYEPLTALPMRRAIVMVICGKADVVHHDPAGPVIHS
MLBr_01254|M.leprae_Br4923 GSIWNRRRVLLLNSTYEPLTALPTRRAIIMVICGKADVVHVDPAGPVVHS
MAB_1567|M.abscessus_ATCC_1997 GSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHS
Mvan_4063|M.vanbaalenii_PYR-1 GSVWGRRRVLLLNSTYEPLTALPLRRAVIMLMCGKADVVHDDPVGPVIHS
MSMEG_4694|M.smegmatis_MC2_155 ASLWGRRRVLLLNATYEPLTALPLRRAVIMVVCGKADVVHDDPTSPVIHS
TH_0922|M.thermoresistible__bu --------VLLLNSTYEPLTALTMRRALVMVLCGKADVVHDDPNGPVIHS
Mflv_3897|M.gilvum_PYR-GCK NTVMDRGNGLCR---YCEFPASEIDHIVPVARGGGNDLANLVPACRECNS
* * :.* : : : * *:.: * :*
Mb2496c|M.bovis_AF2122/97 STRSILVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGGKADTV
Rv2469c|M.tuberculosis_H37Rv ATRSILVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGGKADTV
MMAR_3820|M.marinum_M ATRTIVVPSVIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MUL_3745|M.ulcerans_Agy99 ATQTIVVPSVIQLRTYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MAV_1702|M.avium_104 ATSSIVMPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MLBr_01254|M.leprae_Br4923 ATRSITVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTV
MAB_1567|M.abscessus_ATCC_1997 ATTSVAVPSVIRLRTFVRVPYRARVPMTRAALMHRDRFRCAYCGGRADTI
Mvan_4063|M.vanbaalenii_PYR-1 ATRSIAVPTVIRLRTFVRVPYRARIPMTRAALMHRDRFRCAYCSAKADTV
MSMEG_4694|M.smegmatis_MC2_155 ASRSIVVPSVIRLRTYVRVPYRARVPMTRAALMHRDRFRCAYCGGRADTV
TH_0922|M.thermoresistible__bu ATRALVMPSVIRLRTYVRVPYRARVPMTRAALMHRDRFRCAYCGGKADTI
Mflv_3897|M.gilvum_PYR-GCK EKRDLLP------EEWADKRRADGKPWPIPTFIQRVKFLCHWY--LPASQ
. : . :. * . .::::* :* * : . :
Mb2496c|M.bovis_AF2122/97 DHVVPRSRGGAHSWENCVACCSPCNHRKGDRLLTELGWALRRAPLPPTGP
Rv2469c|M.tuberculosis_H37Rv DHVVPRSRGGAHSWENCVACCSPCNHRKGDRLLTELGWALRRAPLPPTGP
MMAR_3820|M.marinum_M DHVVPRSRGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPTGQ
MUL_3745|M.ulcerans_Agy99 DHVVPRSRGGEHSWENCVACCSACNHRKGDKLLTELGWSLRRTPLPPTGQ
MAV_1702|M.avium_104 DHVVPRSRGGDHSWENCVACCSTCNHRKGDKLLNELGWTLRRPPLPPTGQ
MLBr_01254|M.leprae_Br4923 DHVVPRSRGGDHSWENCVACCSTCNHRKGDKLLTELGWVLRRTPVLPTGQ
MAB_1567|M.abscessus_ATCC_1997 DHVIPRSKGGAHSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQ
Mvan_4063|M.vanbaalenii_PYR-1 DHVIPRSRGGAHSWENCVAACSACNHRKADRLLSELGWSLHTTPLPPKGQ
MSMEG_4694|M.smegmatis_MC2_155 DHVVPRSRGGEHSWENCVAACATCNHRKADRLLTELGWTLRCVPMPPKGQ
TH_0922|M.thermoresistible__bu DHVVPRSRGGAHSWENCVAACSACNHRKADRLLSELGWTLRAVPRPPKGQ
Mflv_3897|M.gilvum_PYR-GCK RHKGRFTLREPEKFRGLVVAARDCAELDG---------------------
* : ..:.. *... * . ..
Mb2496c|M.bovis_AF2122/97 HWRLLSAVKELDPSWARYLG-EGAA
Rv2469c|M.tuberculosis_H37Rv HWRLLSAVKELDPSWARYLG-EGAA
MMAR_3820|M.marinum_M HWRLLSTIKELDPSWARYLG-EGAA
MUL_3745|M.ulcerans_Agy99 HWRLLSTIKELDPSWARYLG-EGAA
MAV_1702|M.avium_104 HWRLLSTVKELDPAWARYLG-EGAA
MLBr_01254|M.leprae_Br4923 HWRLLSTVKELDPAWARYLG-GGAA
MAB_1567|M.abscessus_ATCC_1997 HWRLLSSVKELDPAWVRYLG-EGAA
Mvan_4063|M.vanbaalenii_PYR-1 HWRLLSSVKELDPAWVRYLG-EGAA
MSMEG_4694|M.smegmatis_MC2_155 HWRLLSTVKELDPAWVRYLG-EGAA
TH_0922|M.thermoresistible__bu HWRLLSTVKELDPVWVRYLGGEGAA
Mflv_3897|M.gilvum_PYR-GCK ----------------------GAA
***