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VSSKNSSLNSFGAKDTLKVGDNSYEIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIEAIAKWD PSADPSVEIQFTPARVIMQDFTGVPCIVDLATMREAVGELGGDPQQVNPLAPADLVIDHSVIADLFGRAD AFERNVEIEYERNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEYLASVVMARSDAEGNTVAYPDTCV GTDSHTTMENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKITGERRPGVTATDVVLTVTEMLRQHG VVGKFVEFYGDGVDEVPLANRATLGNMSPEFGSTAAIFPIDDVTIEYLRLTGRSEEQLALVEAYAKEQGM WHDPSREPKFSEYLELDLADVVPSIAGPKRPQDRIALDDAKNAFRKDIHNYVENNHPAPETKLDDTIDDT FPASDPATLQFADDGAVNMHSAANGADGRPTKPVTVKSDEHGEFVLDHGAVVIAAITSCTNTSNPEVMIG AALLAKNAVDKGLARKPWVKTTMAPGSQVVTDYYNKAGLWPYLEKLGFFLVGYGCTTCIGNSGPLPEEVS KAINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGSMDFDFESDSLGNDSDGNPVFLKD IWPSQKDISDTIAEAISQEMFTKNYADVFKGDERWRNLPTPSGNTFEWDQDSTYVRKPPYFEGMPAEPQP VTDISGARVLALLGDSVTTDHISPAGAIKPGTPAAEYLESHGVERKDYNSYGSRRGNHEVMIRGTFANIR LKNQLLDDVSGGYTRDFTKEGEQAFIYDAAQNYAEQNIPLVVLGGKEYGSGSSRDWAAKGTSLLGVRAVI TESFERIHRSNLIGMGVIPLQFPEGESAASLKLDGTETFDITGIEELNNGKTPKTVKVTATKPDGGKVEF DAVVRIDTPGEADYYRNGGILQYVLRNMLKS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3665 | - | - | 100% (941) | aconitate hydratase |
| M. gilvum PYR-GCK | Mflv_4227 | - | 1e-17 | 24.44% (401) | isopropylmalate isomerase large subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1511c | acn | 0.0 | 83.17% (945) | aconitate hydratase |
| M. tuberculosis H37Rv | Rv1475c | acn | 0.0 | 83.17% (945) | aconitate hydratase |
| M. leprae Br4923 | MLBr_01814 | acn | 0.0 | 80.28% (943) | aconitate hydratase |
| M. abscessus ATCC 19977 | MAB_2730 | - | 0.0 | 82.30% (938) | aconitate hydratase ACN |
| M. marinum M | MMAR_2282 | acn | 0.0 | 83.78% (937) | aconitate hydratase Acn |
| M. avium 104 | MAV_3303 | acnA | 0.0 | 83.71% (939) | aconitate hydratase |
| M. smegmatis MC2 155 | MSMEG_3143 | acnA | 0.0 | 84.36% (946) | aconitate hydratase 1 |
| M. thermoresistible (build 8) | TH_0252 | acn | 0.0 | 84.39% (948) | PROBABLE IRON-REGULATED ACONITATE HYDRATASE ACN (Citrate |
| M. ulcerans Agy99 | MUL_1484 | acn | 0.0 | 84.12% (938) | aconitate hydratase |
| M. vanbaalenii PYR-1 | Mvan_2745 | - | 0.0 | 85.12% (954) | aconitate hydratase 1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2282|M.marinum_M ---------------------------------MNSFGARNTLEVGDKSY
MUL_1484|M.ulcerans_Agy99 ---------------------------MTTKDSVNSFGARNTLEVGDKSY
Mb1511c|M.bovis_AF2122/97 ----------------------------MTSKSVNSFGAHDTLKVGEKSY
Rv1475c|M.tuberculosis_H37Rv ----------------------------MTSKSVNSFGAHDTLKVGEKSY
MLBr_01814|M.leprae_Br4923 --------------------------MISSKDSVNSFSARDTLKIGDNSY
MAV_3303|M.avium_104 -----------------------------MTDSVNSFGARNTLKVGDKSY
TH_0252|M.thermoresistible__bu -----------------------VSKGNTKGSSLNSFDARGTLTVGDRKF
MAB_2730|M.abscessus_ATCC_1997 MVAPPEPRLAQPAGGWPSSFGADVTSSPNKTESVNSFGARGTLQVGDESY
MSMEG_3143|M.smegmatis_MC2_155 -----------------------MSSENTGKSSLNSFGARDTLTVGDQSY
Mvan_2745|M.vanbaalenii_PYR-1 -----------------------MSS---KNSSLNSYGAKDTLKVGDNSY
Mflv_3665|M.gilvum_PYR-GCK -----------------------MSS---KNSSLNSFGAKDTLKVGDNSY
:**:.*:.** :*:..:
MMAR_2282|M.marinum_M QIYRLDAVPNTKKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPQAE
MUL_1484|M.ulcerans_Agy99 QIYRLDAVPNTKKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPQAE
Mb1511c|M.bovis_AF2122/97 QIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPKAE
Rv1475c|M.tuberculosis_H37Rv QIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPKAE
MLBr_01814|M.leprae_Br4923 QIYRLDAVSNTKRLPYSLKVLAENLLRNEDGKNITKDHIEAIANWDRQAE
MAV_3303|M.avium_104 QIYRLDAVPNTEKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPKAE
TH_0252|M.thermoresistible__bu DIYRLSAVPGTDKLPYSLKVLAENLLRTEDGANITKEHIEALANWDPNAE
MAB_2730|M.abscessus_ATCC_1997 EIFRLNAVPGTEKLPYSLKVLAENLLRTEDGANITKDHVLALANWDPSAE
MSMEG_3143|M.smegmatis_MC2_155 EIYRLNAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIEAIANWDPNAE
Mvan_2745|M.vanbaalenii_PYR-1 EIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIEAIANWDPEAE
Mflv_3665|M.gilvum_PYR-GCK EIYRLDAVPGTEKLPYSLKVLAENLLRTEDGANITKDHIEAIAKWDPSAD
:*:**.**..* :**************.*** ****:*: *:*:** .*:
MMAR_2282|M.marinum_M PSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGQPDKVNPLAPAD
MUL_1484|M.ulcerans_Agy99 PSIEIQYTPARVVMQDFTGVPCIVDLATMREAIGDLGGQPDKVNPLAPAD
Mb1511c|M.bovis_AF2122/97 PSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD
Rv1475c|M.tuberculosis_H37Rv PSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPAD
MLBr_01814|M.leprae_Br4923 PSIEIQYTPARIVMQDFTGVPCIVDLATMREAIGDLGGNPEKVNPLARVD
MAV_3303|M.avium_104 PSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPEKVNPLAPAD
TH_0252|M.thermoresistible__bu PSVEIQFTPARVVMQDFTGVPCIVDLATMREAIAELGGDPEKVNPLAPAD
MAB_2730|M.abscessus_ATCC_1997 PSVEIQFTPARVVMQDFTGVPCVVDLATMREAVAALGGDPDKVNPLSPAE
MSMEG_3143|M.smegmatis_MC2_155 PSIEIQFTPARVIMQDFTGVPCIVDLATMREAVAALGGDPNKVNPLAPAE
Mvan_2745|M.vanbaalenii_PYR-1 PSIEIQFTPARVLMQDFTGVPCIVDLATMREAVAALGGDPAKVNPLSPAE
Mflv_3665|M.gilvum_PYR-GCK PSVEIQFTPARVIMQDFTGVPCIVDLATMREAVGELGGDPQQVNPLAPAD
**:***:****::*********:*********:. ***:* :****: .:
MMAR_2282|M.marinum_M LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVP
MUL_1484|M.ulcerans_Agy99 LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVP
Mb1511c|M.bovis_AF2122/97 LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVP
Rv1475c|M.tuberculosis_H37Rv LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVP
MLBr_01814|M.leprae_Br4923 LVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFNDFKVVP
MAV_3303|M.avium_104 LVIDHSVIADLFGTADAFERNVEIEYQRNGERYQFLRWGQGAFSDFKVVP
TH_0252|M.thermoresistible__bu LVIDHSVIADLFGRPDAFERNVEIEYQRNGERYQFLRWGQGAFNDFKVVP
MAB_2730|M.abscessus_ATCC_1997 MVIDHSVILDVFGTADAFERNVELEYERNAERYQFLRWGQGAFDDFKVVP
MSMEG_3143|M.smegmatis_MC2_155 LVIDHSVILDVFGNASAFERNVELEYERNAERYQFLRWGQGAFDDFKVVP
Mvan_2745|M.vanbaalenii_PYR-1 MVIDHSVILDVFGRADAFERNVELEYERNGERYQFLRWGQGAFDDFKVVP
Mflv_3665|M.gilvum_PYR-GCK LVIDHSVIADLFGRADAFERNVEIEYERNGERYQFLRWGQGAFDDFKVVP
:******* *:** ..*******:**:**.*************.******
MMAR_2282|M.marinum_M PGTGIVHQVNIEYLASVVMDRDG-----------VAYPDTCVGTDSHTTM
MUL_1484|M.ulcerans_Agy99 PGTGIVHQVNIEYLASVVMDRDG-----------VAYPDTCVGTDSHTTM
Mb1511c|M.bovis_AF2122/97 PGTGIVHQVNIEYLASVVMTRDG-----------VAYPDTCVGTDSHTTM
Rv1475c|M.tuberculosis_H37Rv PGTGIVHQVNIEYLASVVMTRDG-----------VAYPDTCVGTDSHTTM
MLBr_01814|M.leprae_Br4923 PGTGIVHQVNIEYLASVVMTQENTQG------TVVAYPDTCVGTDSHTTM
MAV_3303|M.avium_104 PGTGIVHQVNIEYLARVVMERDG-----------VAYPDTCVGTDSHTTM
TH_0252|M.thermoresistible__bu PGTGIVHQVNIEYLASVVMDRDG-----------VAYPDTCVGTDSHTTM
MAB_2730|M.abscessus_ATCC_1997 PGTGIVHQVNIEYLARTVMVRN-----------GQAYPDTCVGTDSHTTM
MSMEG_3143|M.smegmatis_MC2_155 PGTGIVHQVNIEYLARTVMVRD-----------GVAYPDTCVGTDSHTTM
Mvan_2745|M.vanbaalenii_PYR-1 PGTGIVHQVNIEYLARVVMVRDRAGEAGEGDSISVAYPDTCVGTDSHTTM
Mflv_3665|M.gilvum_PYR-GCK PGTGIVHQVNIEYLASVVMARSDAEG------NTVAYPDTCVGTDSHTTM
*************** .** :. ***************
MMAR_2282|M.marinum_M VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIQPGVTATDV
MUL_1484|M.ulcerans_Agy99 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIQPGVTATDV
Mb1511c|M.bovis_AF2122/97 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFRLTGEIQPGVTATDV
Rv1475c|M.tuberculosis_H37Rv VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFRLTGEIQPGVTATDV
MLBr_01814|M.leprae_Br4923 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPWVVGFKLSGEIQPGVTATDV
MAV_3303|M.avium_104 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIQPGVTATDV
TH_0252|M.thermoresistible__bu VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGERQPGVTATDI
MAB_2730|M.abscessus_ATCC_1997 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIQPGVTATDV
MSMEG_3143|M.smegmatis_MC2_155 VNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLSGEIKPGVTATDV
Mvan_2745|M.vanbaalenii_PYR-1 ENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIKPGVTATDV
Mflv_3665|M.gilvum_PYR-GCK ENGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKITGERRPGVTATDV
***************************** ****:::** :*******:
MMAR_2282|M.marinum_M VLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
MUL_1484|M.ulcerans_Agy99 VLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
Mb1511c|M.bovis_AF2122/97 VLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
Rv1475c|M.tuberculosis_H37Rv VLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
MLBr_01814|M.leprae_Br4923 VLTVTEMLRRHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
MAV_3303|M.avium_104 VLTVTEMLRKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIF
TH_0252|M.thermoresistible__bu VLTVTEMLREHGVVGKFVEFYGEGVAAVPLANRATLGNMSPEFGSTAAIF
MAB_2730|M.abscessus_ATCC_1997 VLTVTDMLRKHGVVGKFVEFYGKGVAEVPLANRATLGNMSPEFGSTAAIF
MSMEG_3143|M.smegmatis_MC2_155 VLTVTDMLRRHGVVGKFVEFYGKGVAEVPLANRATLGNMSPEFGSTAAIF
Mvan_2745|M.vanbaalenii_PYR-1 VLTVTDMLRKHGVVGKFVEFYGNGVAEVPLANRATLGNMSPEFGSTAAMF
Mflv_3665|M.gilvum_PYR-GCK VLTVTEMLRQHGVVGKFVEFYGDGVDEVPLANRATLGNMSPEFGSTAAIF
*****:***.************.** *********************:*
MMAR_2282|M.marinum_M PIDEETIKYLELTGRSAEQVALVAAYAKEQGMWHDPKHEPVLSEYLELNL
MUL_1484|M.ulcerans_Agy99 PIDEETIKYLELTGRSAEQVALVAAYAKEQGMWHDPKHEPVFSEYLELNL
Mb1511c|M.bovis_AF2122/97 PIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNL
Rv1475c|M.tuberculosis_H37Rv PIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNL
MLBr_01814|M.leprae_Br4923 PIDEETINYLRFTGRTPEQVALVEGYAKEQGMWHDPKNEPTFSEYLELNL
MAV_3303|M.avium_104 PIDQETIDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDL
TH_0252|M.thermoresistible__bu PIDEETISYLRFTGRSEEQLALVEAYAKEQGLWHDPQRQPQYSEYLELDL
MAB_2730|M.abscessus_ATCC_1997 PIDDETINYLRLTGRDEAQLALVEAYAREQGMWHDADHEPAFSEYLELDL
MSMEG_3143|M.smegmatis_MC2_155 PIDEETINYLRLTGRTDEQLALVEAYAKAQGMWHDPEREPVFSEYLELDL
Mvan_2745|M.vanbaalenii_PYR-1 PIDEETINYLRLTGRTDEQLALVEAYAKEQGMWHDPAKEPVFSEYLELDL
Mflv_3665|M.gilvum_PYR-GCK PIDDVTIEYLRLTGRSEEQLALVEAYAKEQGMWHDPSREPKFSEYLELDL
***: **.**.:*** *:*** **: **:***. .:* ******:*
MMAR_2282|M.marinum_M SDVVPSIAGPKRPQDRIVLSEAKGTFREQITHYVSDDS--SAHDQHSKLD
MUL_1484|M.ulcerans_Agy99 SDVVPSIAGPKRPQDRIVLAEAKGTFREQITHYVSDDS--SAHDQHSKLD
Mb1511c|M.bovis_AF2122/97 SDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLD
Rv1475c|M.tuberculosis_H37Rv SDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLD
MLBr_01814|M.leprae_Br4923 SDVVPSISGPKRPQDRICLAQAKSTFRAQIPKYVDGSS---LHNQHSKLD
MAV_3303|M.avium_104 SQVVPSIAGPKRPQDRIALSQAKSVFREQIPSYVGDGD---GQQGYSKLD
TH_0252|M.thermoresistible__bu STVVPSIAGPKRPQDRISLNEAKSAFRRDLADYVDDGE---HSTEYTKLD
MAB_2730|M.abscessus_ATCC_1997 STVVPSISGPKRPQDRIELSDAKNAFRKDIHNYVEENH----PAPHTNLD
MSMEG_3143|M.smegmatis_MC2_155 STVVPSISGPKRPQDRIELTDAKNAFRKDIHNYVEQNH----PTPETKLD
Mvan_2745|M.vanbaalenii_PYR-1 STVVPSIAGPKRPQDRIELTDAKNAFRKDIHNYVEENH----PTPETKLD
Mflv_3665|M.gilvum_PYR-GCK ADVVPSIAGPKRPQDRIALDDAKNAFRKDIHNYVENNH----PAPETKLD
: *****:********* * :**..** :: ** . ::**
MMAR_2282|M.marinum_M EVVEETFPASDPGQLTFANDDVA---AVHSAAAHADGRVSKPVRVRSDEL
MUL_1484|M.ulcerans_Agy99 EVVEETFPASDPGQLTFANDDVA---AVHSAAAHADGRVSKPVRVRSDEL
Mb1511c|M.bovis_AF2122/97 EVVEETFPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDEL
Rv1475c|M.tuberculosis_H37Rv EVVEETFPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDEL
MLBr_01814|M.leprae_Br4923 EVVEETCPASDPGKLSFTNNDEV---VMQSAAAHANGRVSNPVRIKTQEL
MAV_3303|M.avium_104 EVVDETFPASDPGAPSNGHADDLP--AVQSAAAHANGRPSNPVTVRSDEL
TH_0252|M.thermoresistible__bu EAVDETFPASDPVRNTEFADNGTP-AHVHSAAVEPTGRPTKRVRVKSDEL
MAB_2730|M.abscessus_ATCC_1997 EAVEESFPASDSAVLSFAEDDA----VIPSAANGGEGRPSKPVKVTSAER
MSMEG_3143|M.smegmatis_MC2_155 EAVEESFPASDPVSLSFADDGAPD--MRPSAANGATGRPTNPVLVHSEER
Mvan_2745|M.vanbaalenii_PYR-1 EAVEESFPASDSVSLSFADDGAVD--ARPSAANGATGRPSKPVTVKSAER
Mflv_3665|M.gilvum_PYR-GCK DTIDDTFPASDPATLQFADDGAV---NMHSAANGADGRPTKPVTVKSDEH
:.:::: ****. . *** ** :: * : : *
MMAR_2282|M.marinum_M GEFVLDHGAVVIAAITSCTNTSNPEVMLGAALLARNAVDKGLTSKPWVKT
MUL_1484|M.ulcerans_Agy99 GEFVLDHGAVVIAAITSCTNTSNPEVMLGAALLARNAVDKGLTSKPWVKT
Mb1511c|M.bovis_AF2122/97 GEFVLDHGAVVIAAITSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKT
Rv1475c|M.tuberculosis_H37Rv GEFVLDHGAVVIAAITSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKT
MLBr_01814|M.leprae_Br4923 GEFVLDHGAVVIAAITSCTNTSNPEVMLCAALLARNAVEKGLASKPWVKT
MAV_3303|M.avium_104 GEFVLDHGAVVIAAVTSCTNTSNPEVMLGAALLARNAVEKGLASKPWVKT
TH_0252|M.thermoresistible__bu GEFELDHGAVVIAAITSCTNTSNPEVMLGAALLAKNAVDKGLATKPWVKT
MAB_2730|M.abscessus_ATCC_1997 GNFVLDHGAVVVAGITSCTNTSNPSVMLGAALLAKKAVEKGLTTKPWVKT
MSMEG_3143|M.smegmatis_MC2_155 GDFVLDHGAVVVAGITSCTNTSNPSVMLGAALLAKKAVEKGLTTKPWVKT
Mvan_2745|M.vanbaalenii_PYR-1 GEFVLDHGAVVVAGITSCTNTSNPSVMLGAALLAKKAVEKGLSTKPWVKT
Mflv_3665|M.gilvum_PYR-GCK GEFVLDHGAVVIAAITSCTNTSNPEVMIGAALLAKNAVDKGLARKPWVKT
*:* *******:*.:*********.**: *****::**:***: ******
MMAR_2282|M.marinum_M TMAPGSQVVNDYYDKAGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEDISK
MUL_1484|M.ulcerans_Agy99 TMAPGSQVVNDYYDKAGLWPYLEKLGFFLVGYGCTTCIGNSGPLPEEISK
Mb1511c|M.bovis_AF2122/97 TIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISK
Rv1475c|M.tuberculosis_H37Rv TIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISK
MLBr_01814|M.leprae_Br4923 TMAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISK
MAV_3303|M.avium_104 TMAPGSQVVHDYYDKAGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISK
TH_0252|M.thermoresistible__bu TMAPGSQVVSDYYEKAGLWPYLEKLGFYLVGYGCTTCIGNSGPLPDEISK
MAB_2730|M.abscessus_ATCC_1997 NMAPGSQVVTDYYNKAGLWPYLEKLGYYLGGYGCTTCIGNTGPLPDEISK
MSMEG_3143|M.smegmatis_MC2_155 NMAPGSQVVTDYYNKAGLWPYLEKLGYYLGGYGCTTCIGNTGPLPEEISK
Mvan_2745|M.vanbaalenii_PYR-1 NMAPGSQVVTDYYNKAGLWPYLEKLGYYLGGYGCTTCIGNTGPLPDEISA
Mflv_3665|M.gilvum_PYR-GCK TMAPGSQVVTDYYNKAGLWPYLEKLGFFLVGYGCTTCIGNSGPLPEEVSK
.:******* ***:::**********::* **********:****:::*
MMAR_2282|M.marinum_M AVNDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDFD
MUL_1484|M.ulcerans_Agy99 AVNDNDLSVAAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDFD
Mb1511c|M.bovis_AF2122/97 AVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGTMDFD
Rv1475c|M.tuberculosis_H37Rv AVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGTMDFD
MLBr_01814|M.leprae_Br4923 AINYNNLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGTMDFD
MAV_3303|M.avium_104 AINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGTMDFD
TH_0252|M.thermoresistible__bu AINDNDLSVAAVLSGNRNFEGRINPDTKMNYLASPPLVIAYALAGTMDFD
MAB_2730|M.abscessus_ATCC_1997 AINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYGIAGTMDFD
MSMEG_3143|M.smegmatis_MC2_155 AINDNDLAVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYGIAGTMDFD
Mvan_2745|M.vanbaalenii_PYR-1 AINDNDLSVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYGLAGTMDFD
Mflv_3665|M.gilvum_PYR-GCK AINDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGSMDFD
*:* *:*:*:*************.**.***********:**.:**:****
MMAR_2282|M.marinum_M FENQPLGTDKEGKDVFLRDIWPSQQDVADTIASAINQEMFTKNYADVFKG
MUL_1484|M.ulcerans_Agy99 FENQPLGTDKEGKDVFLRDIWPSQQDVADTIASAINQEMFTKNYADVFKG
Mb1511c|M.bovis_AF2122/97 FQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG
Rv1475c|M.tuberculosis_H37Rv FQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKG
MLBr_01814|M.leprae_Br4923 FESQPLDTDKNGKAVYLKDIWPSQKDVTDTIASAINQEMFTKNYADVFKG
MAV_3303|M.avium_104 FEKQPLGKDKDGNDVYLKDIWPSQKDVSDTIASAINSEMFTKNYADVFKG
TH_0252|M.thermoresistible__bu FESQPLGKDSDGNDVFLRDIWPSQQEIEDTIRSAISQEMFTKNYADVFKG
MAB_2730|M.abscessus_ATCC_1997 FETDPLGKDHDGNDVFLKDIWPSASEIEETIASSINREMFTSSYADVFKG
MSMEG_3143|M.smegmatis_MC2_155 FESDPLGQDSEGNDVFLRDIWPSAAEIEETIASSINREMFTESYADVFKG
Mvan_2745|M.vanbaalenii_PYR-1 FEADPLGQDGDGNDVFLKDIWPSAAEIQETITSSINREMFADSYADVFKG
Mflv_3665|M.gilvum_PYR-GCK FESDSLGNDSDGNPVFLKDIWPSQKDISDTIAEAISQEMFTKNYADVFKG
*: :.*. * :*: *:*:***** :: :** :*. ***: .*******
MMAR_2282|M.marinum_M DERWRNLPTPSGNTFDWDQSSTYVRKPPYFEGMAAAPTPVSDITGARVLA
MUL_1484|M.ulcerans_Agy99 DERWRNLPTPSGNTFDWDQSSTYVRKPPYFEGMAAAPAPVSDITGARVLA
Mb1511c|M.bovis_AF2122/97 DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLA
Rv1475c|M.tuberculosis_H37Rv DDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLA
MLBr_01814|M.leprae_Br4923 DERWRNLPTPSGNTFDWEQNSTYVRKPPYFEGMSVEPKPVRNITGARVLA
MAV_3303|M.avium_104 DERWRNLPTPSGNTFEWSPDSTYVRKPPYFEGMPAEPEPVADISGARVLA
TH_0252|M.thermoresistible__bu DERWRSLPTPSGSTFQWDPESTYVRKPPYFEGMSAEPAPVSDITGARVLA
MAB_2730|M.abscessus_ATCC_1997 DERWRGLPTPEGNTFAWSDDSTYVRKAPYFDGMPLEPTPVTDIKGARVLA
MSMEG_3143|M.smegmatis_MC2_155 DDRWRSLPTPEGDTFEWDPASTYVRKAPYFDGMPAEPEPVSDIKGARVLA
Mvan_2745|M.vanbaalenii_PYR-1 DERWRSLPTPEGNTFEWDEDSTYVRKAPYFDGMPAEPEPVKDIKGARVLA
Mflv_3665|M.gilvum_PYR-GCK DERWRNLPTPSGNTFEWDQDSTYVRKPPYFEGMPAEPQPVTDISGARVLA
*:***.****.*.** *. ******.***:**. * ** :*.******
MMAR_2282|M.marinum_M LLGDSVTTDHISPAGAIKPGTPAAQYLDEHGVARKDYNSFGSRRGNHEVM
MUL_1484|M.ulcerans_Agy99 LLGDSVTTDHISPAGAIKPGTPAAQYLDEHGVARKDYNSFGSRRGNHEVM
Mb1511c|M.bovis_AF2122/97 LLGDSVTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVM
Rv1475c|M.tuberculosis_H37Rv LLGDSVTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVM
MLBr_01814|M.leprae_Br4923 LLDDSVTTDHISPASTIKPGTPAAQYLDTHGVDRKDYNSFGSRRGNHEVM
MAV_3303|M.avium_104 LLGDSVTTDHISPAGSIKPGTPAAQYLDEHGVDRKDYNSFGSRRGNHEVM
TH_0252|M.thermoresistible__bu LLGDSVTTDHISPAGTIQPGTPAAQYLESHGVQRKDYNSYGSRRGNHEVM
MAB_2730|M.abscessus_ATCC_1997 LLGDSVTTDHISPAGSIKSGTPAAQYLDEHGVERKDYNSLGSRRGNHEVM
MSMEG_3143|M.smegmatis_MC2_155 LLGDSVTTDHISPAGAIKPGTPAAQYLDANGVERKDYNSLGSRRGNHEVM
Mvan_2745|M.vanbaalenii_PYR-1 LLGDSVTTDHISPAGSIKKGTPAAQYLEEHGVEPKDFNSLGSRRGNHEVM
Mflv_3665|M.gilvum_PYR-GCK LLGDSVTTDHISPAGAIKPGTPAAEYLESHGVERKDYNSYGSRRGNHEVM
**.***********.:*: *****.**: :** **:** **********
MMAR_2282|M.marinum_M IRGTFANIRLRNQLLD-----DVSGGYTRDFTQDGAPQAFIYDAAQNYAA
MUL_1484|M.ulcerans_Agy99 IRGTFANIRLRNQLLD-----DVSGGYTRDFTQDGAPQAFIYDAAQNYAA
Mb1511c|M.bovis_AF2122/97 IRGTFANIRLRNQLLD-----DVSGGYTRDFTQPGGPQAFIYDAAQNYAA
Rv1475c|M.tuberculosis_H37Rv IRGTFANIRLRNQLLD-----DVSGGYTRDFTQPGGPQAFIYDAAQNYAA
MLBr_01814|M.leprae_Br4923 IRGTFANIRLRNMLLN-----GVAGGYTRDFTKPGAPQAFIYDAAQNYAA
MAV_3303|M.avium_104 IRGTFANIRLRNLLLD-----DVAGGYTRDFTQDGGPQAFIYDAAQNYAA
TH_0252|M.thermoresistible__bu IRGTFANIRLRNRLLDAIVEGGVSGGYTRDFTK-GGEQAFIYDAAQNYAA
MAB_2730|M.abscessus_ATCC_1997 VRGTFANIRLRNQLLD-----DVSGGYTRDFTQDGGPQSFIYDASVNYQK
MSMEG_3143|M.smegmatis_MC2_155 IRGTFANIRLRNQLLD-----DVSGGYTRDFTQPGGPQAFIYDASENYKK
Mvan_2745|M.vanbaalenii_PYR-1 IRGTFANIRLRNQLLD-----DVSGGYTRDFTQDGGPQAFIYDAAQNYAK
Mflv_3665|M.gilvum_PYR-GCK IRGTFANIRLKNQLLD-----DVSGGYTRDFTKEG-EQAFIYDAAQNYAE
:*********:* **: .*:********: * *:*****: **
MMAR_2282|M.marinum_M QNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRVVIAESFERIHRSNLIGM
MUL_1484|M.ulcerans_Agy99 QNIPLVVLGGKEYGSGSSRDWAAKGTLLLGVRVVIAESFERIHRSNLIGM
Mb1511c|M.bovis_AF2122/97 QHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESFERIHRSNLIGM
Rv1475c|M.tuberculosis_H37Rv QHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESFERIHRSNLIGM
MLBr_01814|M.leprae_Br4923 ENIPLVVLSGKEYGSGSSRDWAAKGTLLLGVRAVIAESFERIHRSNLIGM
MAV_3303|M.avium_104 QNIPLVVLGGKEYGSGSSRDWAAKGTRLLGVRAVIAESFERIHRSNLIGM
TH_0252|M.thermoresistible__bu QNIPLVVLGGKEYGSGSSRDWAAKGTALLGVKAVITESFERIHRSNLIGM
MAB_2730|M.abscessus_ATCC_1997 AGIPLVVLGGKEYGSGSSRDWAAKGTRLLGVKAVITESFERIHRSNLIGM
MSMEG_3143|M.smegmatis_MC2_155 AGIPLVVLGGKEYGSGSSRDWAAKGTVLLGVKAVITESFERIHRSNLIGM
Mvan_2745|M.vanbaalenii_PYR-1 EGIPLVVLGGKEYGSGSSRDWAAKGTTLLGVRAVITESFERIHRSNLIGM
Mflv_3665|M.gilvum_PYR-GCK QNIPLVVLGGKEYGSGSSRDWAAKGTSLLGVRAVITESFERIHRSNLIGM
*****:.***************** ****:.**:**************
MMAR_2282|M.marinum_M GVIPLQFPKGQSASSLGLDGTETFDVTGIEELNSGKTPKTVHVKATK--D
MUL_1484|M.ulcerans_Agy99 GVIPLQFPTGQSASSLGLDGTETFDVTGIEELNSGKTPKTVHVKATK--D
Mb1511c|M.bovis_AF2122/97 GVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK--G
Rv1475c|M.tuberculosis_H37Rv GVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATK--G
MLBr_01814|M.leprae_Br4923 GVIPLQFPQGESASSLGLDGTEVFEINGIDVFNNGKTPKTVHVKASK--A
MAV_3303|M.avium_104 GVIPLQFPDGKSAKDLGLDGTEVFDITGIEELNKGKTPKTVHVKASK--N
TH_0252|M.thermoresistible__bu GVLPLQFPQGQSAASLGLDGTETFDITGIEALNEGRTPKTVKVTATK--E
MAB_2730|M.abscessus_ATCC_1997 GVVPLQFPAGESAASLKLDGTETYDISGIEKLNEGSTPKTVQVTATR--E
MSMEG_3143|M.smegmatis_MC2_155 GVIPLQFPAGESAASLKLDGTETYDIEGIEELNSGKTPKTVHVTATK--E
Mvan_2745|M.vanbaalenii_PYR-1 GVIPLQFPKGESAASLKLDGTETFDIEGIEALNEGKTPKTVKVTAKKIAE
Mflv_3665|M.gilvum_PYR-GCK GVIPLQFPEGESAASLKLDGTETFDITGIEELNNGKTPKTVKVTATK--P
**:***** *:** .* *****.::: **: :*.* ***** * *.:
MMAR_2282|M.marinum_M GA---DPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG-
MUL_1484|M.ulcerans_Agy99 GA---DPIEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG-
Mb1511c|M.bovis_AF2122/97 DG---ATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG-
Rv1475c|M.tuberculosis_H37Rv DG---ATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG-
MLBr_01814|M.leprae_Br4923 SG---TTVTFDALVRIDTPGEADYYRNGGILHYVLRNILKSN-
MAV_3303|M.avium_104 GS---DAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSG-
TH_0252|M.thermoresistible__bu DG---SKVEFDAVVRIDTPGEADYYRNGGILHYVLRNMLESK-
MAB_2730|M.abscessus_ATCC_1997 NG---ETVQFDAVVRIDTPGEADYYRNGGILQYVLRNMLAG--
MSMEG_3143|M.smegmatis_MC2_155 DG---SKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKSSK
Mvan_2745|M.vanbaalenii_PYR-1 DGTVSSAVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS--
Mflv_3665|M.gilvum_PYR-GCK DG---GKVEFDAVVRIDTPGEADYYRNGGILQYVLRNMLKS--
.. : ***:******************:*****:* .