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VPVSRREPLLAAWPLLRPRLPRVALSVLLGALSLGSALALTAVSAWLITRAWQMPPVLHLTVAAVTVRAL GISRGLLGYCERLASHDTALRAAGTAREQIFTRLAGGPPDAVMRRSSGDLVSRVGQGVDDLADVIVRAVV PIGVAAVLAIAAVTTIAVISPAAAVVLALSMAVAGVVAPVLAARAVTATETVAAEHHAHRDTAVMLALEH APELRVSGRLDQVLATAGAEQRRWGHALDRAAAPAAVAAAVPTAALGVSVVGAVLAGIALASTVAPTTVA ILMLVPLAAFEGTAALPGAAVALTRGRIAAQRLLSLTDPGNDEADDRRPVVTPPVLEPGDRVAVVGPSGC GKTTLLMQTPGVFFAEDAHLFSTTVRDNLLVARGDATDDELLDALRRCGLGRWLAGLSDGLSTVLVGGAA AVSAGQRRRLLLARALVSNAQTVLLDEPTEHLDASDADAILTGLLTPGALFGPERTVVVATHHLPEHLDV KVISPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3588 | - | - | 100% (496) | ABC transporter, transmembrane region, type 1 |
| M. gilvum PYR-GCK | Mflv_1746 | - | 5e-22 | 26.58% (474) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_3587 | - | 5e-19 | 26.08% (510) | ABC transporter, transmembrane region, type 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1646c | cydC | 1e-153 | 56.83% (549) | cytochrome' transport transmembrane ATP-binding protein ABC |
| M. tuberculosis H37Rv | Rv1620c | cydC | 1e-153 | 56.83% (549) | cytochrome' transport transmembrane ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_01113 | - | 2e-19 | 23.98% (442) | putative ABC transporter, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2633 | - | 1e-126 | 50.67% (523) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2423 | cydC | 1e-157 | 58.44% (539) | cytochrome transmembrane ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3167 | - | 1e-157 | 59.07% (535) | ABC transporter, ATP-binding protein CydC |
| M. smegmatis MC2 155 | MSMEG_3231 | cydD | 1e-21 | 27.15% (512) | ABC transporter, CydDC cysteine exporter (CydDC-E) family |
| M. thermoresistible (build 8) | TH_4206 | - | 6e-94 | 67.55% (265) | PUTATIVE ABC transporter, transmembrane region, type 1 |
| M. ulcerans Agy99 | MUL_1601 | cydC | 1e-150 | 57.60% (526) | component linked with the assembly of cytochrome transport |
| M. vanbaalenii PYR-1 | Mvan_2827 | - | 0.0 | 80.97% (494) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3588|M.gilvum_PYR-GCK -------MPVSRREPLLAAWPLLRPRLPRVALSVLLGALSLGSALALTAV
Mvan_2827|M.vanbaalenii_PYR-1 ---------MSRRDPLARAWPLLGSRAPRIALAVMFGVLALGSALGLTAV
Mb1646c|M.bovis_AF2122/97 MNRPS--AVSRRQRDLLAASGLLGPRLPRILAAVALGVLSLGSALALAGV
Rv1620c|M.tuberculosis_H37Rv MNRPS--AVSRRQRDLLAASGLLGPRLPRILAAVALGVLSLGSALALAGV
MAV_3167|M.avium_104 MPRPDSFASASSGRPLLAAAGLLSPRLPRLAAAITLGVLSLGSALALAGV
MMAR_2423|M.marinum_M ---------MSRSDSLSAAYDLLRPRLPRVLAAIALGVLSLGSALALAGV
MUL_1601|M.ulcerans_Agy99 ----------------------MRPRLPRVLAAIALGVLPLGSALALAGV
TH_4206|M.thermoresistible__bu ------MRHSPTADPLWSMIPLLRPRLPRLALAVTFGVLSLGSALALAGV
MAB_2633|M.abscessus_ATCC_1997 --------MPRTSDPLRHWLFALHVRPARLAMAVMFGVLALGSALGLAGL
MSMEG_3231|M.smegmatis_MC2_155 ---------------------------------MVIAGCTIASAVVLAHI
MLBr_01113|M.leprae_Br4923 -MTMATAPATRSCDFYCTIRRLLKQLVPQRRLSLTVITLGIT-GTAIGII
: . : . : :
Mflv_3588|M.gilvum_PYR-GCK SAWLITR----------AWQMPPVLHLTVAAVTVR---------------
Mvan_2827|M.vanbaalenii_PYR-1 SAWLITR----------AWEMPPVLHLTVAAVTVR---------------
Mb1646c|M.bovis_AF2122/97 SAWLITR----------AWQMPPVLDLSVAVVAVR---------------
Rv1620c|M.tuberculosis_H37Rv SAWLITR----------AWQMPPVLDLSVAVVAVR---------------
MAV_3167|M.avium_104 SAWLITR----------AWQMPPVLDLSVAAVAVR---------------
MMAR_2423|M.marinum_M SAWLITR----------ASQMPPVLDLSIAVVAVR---------------
MUL_1601|M.ulcerans_Agy99 SAWLITR----------ASQMPPVLDLSIAVVAVR---------------
TH_4206|M.thermoresistible__bu SAWLITR----------AWQMPPVLHLTVAVTTVR---------------
MAB_2633|M.abscessus_ATCC_1997 SAWLITR----------AWQMPPVLDLSVAVVAVR---------------
MSMEG_3231|M.smegmatis_MC2_155 VAGIITNP---------ATALGGETDWAPGLVALA---------------
MLBr_01113|M.leprae_Br4923 VPWVLGHTTDLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLSGMN
. :: . . : : . .:
Mflv_3588|M.gilvum_PYR-GCK --------------------ALGISRGLLGYCERLASHDTALRAAGTARE
Mvan_2827|M.vanbaalenii_PYR-1 --------------------ALAISRGVLGYCERLASHDTALRAAATARE
Mb1646c|M.bovis_AF2122/97 --------------------AFAISRGVLHYCERLATHDTALRAAGRART
Rv1620c|M.tuberculosis_H37Rv --------------------AFAISRGVLHYCERLATHDTALRAAGRART
MAV_3167|M.avium_104 --------------------MFAISRGVLHYCERLVTHDTALRAAGAARV
MMAR_2423|M.marinum_M --------------------TFAISRGVLHYCERLATHDIALRAAGTARA
MUL_1601|M.ulcerans_Agy99 --------------------TFAISRGVLHYCERLATHDIALRAAVTARA
TH_4206|M.thermoresistible__bu --------------------ALGISRGVFHYCERLASHDTALRAAEHART
MAB_2633|M.abscessus_ATCC_1997 --------------------ALGISRGIWRYCERLAGHDIALRGAATVRT
MSMEG_3231|M.smegmatis_MC2_155 --------------------VLWSVRVVAQWFQGRLSQRGATAVIGELSR
MLBr_01113|M.leprae_Br4923 LVPGQGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRS
: : : : : .
Mflv_3588|M.gilvum_PYR-GCK QIFTRLAGGPPDAVMRRSSGDLVSRVGQGVDDLADVIVRAVVPIGVAAVL
Mvan_2827|M.vanbaalenii_PYR-1 RLFVRLATGPEDVVMRRSSGDLVSRVGAGVDELSDVVVRAVVPICVAAVL
Mb1646c|M.bovis_AF2122/97 LIYHRLAHGPAAAAVGLHSGDLAARVGADVDELANMLVRALVPIAVAAVL
Rv1620c|M.tuberculosis_H37Rv LIYHRLAHGPAAAAVGLHSGDLAARVGADVDELANMLVRALVPIAVAAVL
MAV_3167|M.avium_104 AVYQRLTRGGAAAAVRLHSGELVARVGADVDELANVLVRALVPMGVAAVL
MMAR_2423|M.marinum_M RIYQRLAEGPVAAAFRLSSGDLVARVGSDVDTLADVLVRALVPVGVAAVL
MUL_1601|M.ulcerans_Agy99 RIYQRLAEGPVAAAFRLSSGDLVARVGSDVDTLADVLVRALVPVDVAAVL
TH_4206|M.thermoresistible__bu TLYTRLAEAPEHVVSRFSSGELVARVGDSVDEVADVLVRAVLPIAVAVVL
MAB_2633|M.abscessus_ATCC_1997 HVYARLTGGP---AGRLRKGAVLERIGTDIDELAETVVRSVIPAAVAAVL
MSMEG_3231|M.smegmatis_MC2_155 QVLSSVTTSSPRRLAADRD-SAAAVVTRGLDGLRPYFTGYLPAVVLAGIL
MLBr_01113|M.leprae_Br4923 DVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLT
: : : .:* : . : : :
Mflv_3588|M.gilvum_PYR-GCK AIAAVTTIAVISPAAAVVLALSMAVAGVVAPVLAARAVTATETVAAEHHA
Mvan_2827|M.vanbaalenii_PYR-1 GVAAVVAIAVMSPAAAAVLAVCLLIAGVVAPALAARAASAAETVAVEHHA
Mb1646c|M.bovis_AF2122/97 AVAATAVVAAVSVPAAVVLAVCLLVAGVVAPWLAGRTAAAQEAIARQHRG
Rv1620c|M.tuberculosis_H37Rv AVAATAVVAAVSVPAAVVLAVCLLVAGVVAPWLAGRTAAAQEAIARQHRG
MAV_3167|M.avium_104 AAAATAVVAAISPAAGGALAICLLVAGFVAPRLAGRAAATQEDIARQQHS
MMAR_2423|M.marinum_M APAAIGVVAVISLPAAAVLTMCFIVAGIIAPSLARRAAQSQEALARQHHA
MUL_1601|M.ulcerans_Agy99 APAAIGVVAVISLPAAAVLTMCFIVAGIIAPSLARRAAQSQEALARQHHA
TH_4206|M.thermoresistible__bu AVAAVSVIAVISPAAAVVLAVCLLIAGVLAPRMAARAVTSTEAVAAQYQS
MAB_2633|M.abscessus_ATCC_1997 GIAATAVVALISIPAAAVMACALLVADVLAPALAARAARARETRGARARA
MSMEG_3231|M.smegmatis_MC2_155 TPAALVVMAAYDWQAAAIVVIALPLIPIFMVLIGLLTAERSAAALTAMTT
MLBr_01113|M.leprae_Br4923 VVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAG-
*. .:. . . . : . :. :
Mflv_3588|M.gilvum_PYR-GCK HRDTAVMLALEHAPELRVSGRLDQVLATAGAEQRRWGHALDRAAAPAAVA
Mvan_2827|M.vanbaalenii_PYR-1 QRDNATMLALEHAPELRVSGRLDDVVAAAGDEQRRWGRAVDRAAAPAAVA
Mb1646c|M.bovis_AF2122/97 MRDTSAMIALEHAPELRVAGALRNVIADSQRRQHAWADALDAAARTGAIA
Rv1620c|M.tuberculosis_H37Rv MRDTSAMIALEHAPELRVAGALRNVIADSQRRQHAWADALDAAARTGAIA
MAV_3167|M.avium_104 QRDRAAMLALEHAPELRIAGLLPEVIAESQRRQRAWGAALDAAGKPAAVA
MMAR_2423|M.marinum_M GRDESAMVALEHAPELRVGGVLPAVIAKSQRQQHAWGEAMDAAARPAAIA
MUL_1601|M.ulcerans_Agy99 GRDESAMVALEHAPELRVGGVLPAVIAKSQRQQHAWGEAMDAAARPAAIA
TH_4206|M.thermoresistible__bu DRNTAAMLALQHAPELRVSGRLEAVITEAERRHHAWGDAADRAAAPAALA
MAB_2633|M.abscessus_ATCC_1997 LHSETAVEILDHAPELRVGGLLPHQLEVARHRRGEWAAAQDRAAAPAAWS
MSMEG_3231|M.smegmatis_MC2_155 LQG-RMLDLIAGIPTLRAVGRAGGSVQRIAELSASHRRSTMATLRISFLS
MLBr_01113|M.leprae_Br4923 RLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLV
. . :: * : : .
Mflv_3588|M.gilvum_PYR-GCK AAVPT--AALGVSVVGAVLAGIALASTVAPTTVAILMLVPLAAFEGTAAL
Mvan_2827|M.vanbaalenii_PYR-1 AAVPT--VAVGVSVLGAVLAGIALSHTAAPTTVAILMLLPLAAFEATGAL
Mb1646c|M.bovis_AF2122/97 EAMPT--AAIGASLLGAVVAGIGMAPTVAPTTLAILMLLPLSAFEATVAL
Rv1620c|M.tuberculosis_H37Rv EAMPT--AAIGASLLGAVVAGIGMAPTVAPTTLAILMLLPLSAFEATVAL
MAV_3167|M.avium_104 EAMPT--AAIGASVLGAVVAAIGMAHAVAPTTLAVLMLLPLSAFEAMTPL
MMAR_2423|M.marinum_M EAVPT--AAIGTSVLGAVVAGILMAPTVAPTTLAVLMLLPLSAFEATNAL
MUL_1601|M.ulcerans_Agy99 EAVPT--AAIGTSVLGAVVAGIIMAPTVAPTTLAVLMLLPLSAFEATNAL
TH_4206|M.thermoresistible__bu NAATT--LAIGAAVLGAVVAAIPLAXXXX------------SARPPSPLP
MAB_2633|M.abscessus_ATCC_1997 AAAPT--IAVGMASVGALAAAVELANHVAPTTLAILVLLPLAAFEASTAL
MSMEG_3231|M.smegmatis_MC2_155 ALVLELLATLGVALVAVSVGLRLVFGDMTLAAGLTALLLAPEVFWPLRRV
MLBr_01113|M.leprae_Br4923 SPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQV
:* :.. .
Mflv_3588|M.gilvum_PYR-GCK PGAAVALTRGRIAAQRLLSLTDPGNDEADD--------------------
Mvan_2827|M.vanbaalenii_PYR-1 PGAAVALTRGRIAAQRLLTLTEP--AELGD--------------------
Mb1646c|M.bovis_AF2122/97 PAAAVQLTRSRIAAARLLDLTGSNRVRETESTVSARLPVGTGVLA-----
Rv1620c|M.tuberculosis_H37Rv PAAAVQLTRSRIAAARLLDLTGSNRVRETESTVSARLPVGTGVLA-----
MAV_3167|M.avium_104 PAAAVQLTRSRIAARRLLELTATEPPRPAG---SVPRPTGPGRLT-----
MMAR_2423|M.marinum_M PAAAVQLTRSRIALHRLIELAGRDVNPPTDTAIATLESPTLGQLS-----
MUL_1601|M.ulcerans_Agy99 PAAAVQLTRSRIALHRLIELAGRDVNPPTDTAIATLESPTLGQLS-----
TH_4206|M.thermoresistible__bu PDSAQGWPPSR---------------------------------------
MAB_2633|M.abscessus_ATCC_1997 PAAAVGIARSRASARHLQELAPDGRGAEPTDVMPSAAAGAAVECS-----
MSMEG_3231|M.smegmatis_MC2_155 GAAFHAAQDGKTAAEQALRLCAEPHPPTGHEVVPAGAP------------
MLBr_01113|M.leprae_Br4923 AGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPHGQVPRINGRVEF
.
Mflv_3588|M.gilvum_PYR-GCK -----------RRPVVTPPVLEPGDRVAVVGPSGCGKTTLLMQTPG----
Mvan_2827|M.vanbaalenii_PYR-1 -----------RRPTVIPLHLEPGDRVAVVGPSGCGKTTLLMQTPG----
Mb1646c|M.bovis_AF2122/97 -ADVCCGHQ-EAQSIRVTIDLPPGARLAVTGASGAGKTTLLMTLAGLLPP
Rv1620c|M.tuberculosis_H37Rv -ADVCCGHQ-EAQSIRVTIDLPPGARLAVTGASGAGKTTLLMTLAGLLPP
MAV_3167|M.avium_104 -ADIHSGHDGAARESRVTLDLRPGARLAVTGASGCGKTTLLMTLAGLLPP
MMAR_2423|M.marinum_M -ADIYSGHS-RAHATRATIELSPGARLAVTGPSGSGKTTLLMTLAGLLSP
MUL_1601|M.ulcerans_Agy99 -ADIYSGHS-RAHATRTTIELSPGARLAVTGPSGSGKTTLLMTLAGLLSP
TH_4206|M.thermoresistible__bu ------------------------------GPP-----------------
MAB_2633|M.abscessus_ATCC_1997 -ELHWHTGN--SVSGPLSFRLPAGARMAVTGASGIGKTSLLTTLAGLTRP
MSMEG_3231|M.smegmatis_MC2_155 ----------VIEVPALKAVMEPGRVTVLTGPNGVGKSTLLQAILGLQES
MLBr_01113|M.leprae_Br4923 QQVSFAYRTGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDV
*.
Mflv_3588|M.gilvum_PYR-GCK ------------------------VFFAEDAHLFSTTVRDNLLVARGDAT
Mvan_2827|M.vanbaalenii_PYR-1 ------------------------VFFAEDAHLFSTTVRDNLLVARGDAT
Mb1646c|M.bovis_AF2122/97 VHGRVLLDGTNLSDFDEDELRSAVSFFAEDAHIFATTVRDNLLTARGDCP
Rv1620c|M.tuberculosis_H37Rv VHGRVLLDGTNLSDFDEDELRSAVSFFAEDAHIFATTVRDNLLTARGDCP
MAV_3167|M.avium_104 LQGQVVLDGVALSEFDECELARAIVFFAEDAHVFATTVRDNLLVARGDCP
MMAR_2423|M.marinum_M LQGQVLLNGISLTRFDDAELRSTIGFFAEDAHIFATTVRDNLLVVRGDCT
MUL_1601|M.ulcerans_Agy99 LQGQVLLNGISLTRFDDAEFRSTIGFFAEDAHIFATTVRDNLLVVRGDCT
TH_4206|M.thermoresistible__bu ------------------------------ARPWPHPCRD----------
MAB_2633|M.abscessus_ATCC_1997 VSGTIRVRNDALADLPAAELPGLIRFFAEDAHLFATTVRDNLLVARGDAP
MSMEG_3231|M.smegmatis_MC2_155 PCGPILVAGVEVGALDRSAWWGRLAWMPHRPVLVPGTVRENLELLG---P
MLBr_01113|M.leprae_Br4923 DSGQILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQAS
. . :
Mflv_3588|M.gilvum_PYR-GCK DDELLDALRRCGLGRWLAGLSDGLSTVLVGGAAAVSAGQRRRLLLARALV
Mvan_2827|M.vanbaalenii_PYR-1 DDELRDALRLAGLGAWLDGLPQGLSTLLVGGAAAVSAGQRRRLLLARALV
Mb1646c|M.bovis_AF2122/97 DDELIEALDRVGLCGWLAGLPEGLSTVLIGGAQAVSAGQRRRLLLARAVL
Rv1620c|M.tuberculosis_H37Rv DDELIEALDRVGLCGWLAGLPEGLSTVLIGGAQAVSAGQRRRLLLARAVL
MAV_3167|M.avium_104 DDELTDALGAVGLDDWLAGLPDGLSTVLTGGAQAISAGQRRRLLLARAVI
MMAR_2423|M.marinum_M DDELVTTLDRVGLGAWLAGLPHGLSTVLIGGAQAVSAGQRRRLLLARAAL
MUL_1601|M.ulcerans_Agy99 DDELVTTLDKVGLGAWLAGLPHGLSTVLIVGAQAVSAGQRRRLLLARAAL
TH_4206|M.thermoresistible__bu --PSLHPWRRSSCPGWVS---------------------RRRFRATYARP
MAB_2633|M.abscessus_ATCC_1997 DGDLVDALSVVGLGPWLESLPQGLDTVMTAGAGSVSGGQRRRILLARALL
MSMEG_3231|M.smegmatis_MC2_155 VPGLDEVCRSVGFDEVLGELPDGSETPLGRGGVGLSLGQRQRLGLVRALG
MLBr_01113|M.leprae_Br4923 EDEVMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFL
: :: : . *
Mflv_3588|M.gilvum_PYR-GCK SNAQTVLLDEPTEHLDASDADAILTGLLTPG-ALFGPERTVVVATHHLPE
Mvan_2827|M.vanbaalenii_PYR-1 SAAPTVLLDEPTEHLDASDADQILTDLLTPG-TLFSPQQTVVVATHHLPE
Mb1646c|M.bovis_AF2122/97 SPARIVLLDEPVEHLDAANAD-LLRDLLAPNSGIMSAMRTVVVATHHLPN
Rv1620c|M.tuberculosis_H37Rv SPARIVLLDEPVEHLDAANAD-LLRDLLAPNSGIMSAMRTVVVATHHLPN
MAV_3167|M.avium_104 SPARIVLLDEPTEHLDAGDAERLLRDLLAPDSRLLSPPRTVVVATHHLPE
MMAR_2423|M.marinum_M SPAQIVLLDEPTEHLDATDADRILRDLLSSETGLLPVAKTIVVATHHLSE
MUL_1601|M.ulcerans_Agy99 SPAQIVLLDEPTEHLDAIDADRILRDLLSSETGLLPVAKTIVVATHHLSE
TH_4206|M.thermoresistible__bu GPP---------------------------------PWRTPI--------
MAB_2633|M.abscessus_ATCC_1997 SRVPVLLLDEPTEHLDGRDSDSIMRKLLNAN-SSLLAGRTVVVATHHLPD
MSMEG_3231|M.smegmatis_MC2_155 APADVLLLDEPTAHLDGALEDRVLAAIVARA----RAGATVVMVGHRAPV
MLBr_01113|M.leprae_Br4923 ARPQLLILDEATSSIDTR-----TEALIARATHDLLQDRTSFIIAHHLPT
. * .
Mflv_3588|M.gilvum_PYR-GCK HLDVKVISPT---------------------------
Mvan_2827|M.vanbaalenii_PYR-1 GVPVTVVSPT---------------------------
Mb1646c|M.bovis_AF2122/97 DIQCAELSIATDQRCRRRGTNSSDNNTNASAKT----
Rv1620c|M.tuberculosis_H37Rv DIQCAELSIATDQRCRRRGTNSSDNNTNASAKT----
MAV_3167|M.avium_104 GIGCRELRVD-------RGPAAG--------------
MMAR_2423|M.marinum_M NIRCDRMNIPSRQEVSPKVTPARHELQ----------
MUL_1601|M.ulcerans_Agy99 NIRCDRMNIPSRQEVSPKVTPARHELQ----------
TH_4206|M.thermoresistible__bu -------------------------------------
MAB_2633|M.abscessus_ATCC_1997 SVSCLRIQLGDTVQV----------------------
MSMEG_3231|M.smegmatis_MC2_155 LAAADHVVTMESSLVAP--------------------
MLBr_01113|M.leprae_Br4923 IRDADHILVVAAGKIVEQGSHAKLLARRGAYYRMTQA