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MTAADDNYTGHVEPRTAARRVLPGASIVKASVGPMDNNAYLVTCSQTGETLLIDAANDAALLLELIERYA PTLSLIVTSHQHQDHWLALEEVVAATGAPTAAHSLDAGPLPVTPDRLLSGGDTVTVGALNFDVIHLRGHT PGSVALALGGPATDDRVHLFTGDCLFPGGVGKTWKEGDFEQLLGDVSSRVFDVFPDQTVVYPGHGDDTTL GTERPHLGEWRERGW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3549 | - | - | 100% (225) | beta-lactamase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2765 | - | 7e-21 | 32.23% (211) | beta-lactamase domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5123 | - | 8e-15 | 30.11% (186) | beta-lactamase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1663c | - | 1e-100 | 75.11% (225) | hypothetical protein Mb1663c |
| M. tuberculosis H37Rv | Rv1637c | - | 1e-100 | 75.11% (225) | hypothetical protein Rv1637c |
| M. leprae Br4923 | MLBr_01391 | - | 1e-97 | 73.28% (232) | hypothetical protein MLBr_01391 |
| M. abscessus ATCC 19977 | MAB_2314c | - | 3e-81 | 63.51% (222) | Beta-lactamase-like |
| M. marinum M | MMAR_2442 | - | 1e-102 | 76.44% (225) | hypothetical protein MMAR_2442 |
| M. avium 104 | MAV_3136 | - | 1e-101 | 76.32% (228) | hydrolase |
| M. smegmatis MC2 155 | MSMEG_3810 | - | 1e-98 | 75.68% (222) | hydrolase |
| M. thermoresistible (build 8) | TH_1580 | - | 1e-109 | 80.89% (225) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1621 | - | 1e-101 | 75.56% (225) | hypothetical protein MUL_1621 |
| M. vanbaalenii PYR-1 | Mvan_3340 | - | 1e-121 | 90.67% (225) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3549|M.gilvum_PYR-GCK ---------------------------------------MTAADDNYTGH
Mvan_3340|M.vanbaalenii_PYR-1 ---------------------------------------MTVVDDNYTGH
TH_1580|M.thermoresistible__bu ---------------------------------------MTVVAEEYTGH
MMAR_2442|M.marinum_M ---------------------------------------MTVVDDNYTGH
MUL_1621|M.ulcerans_Agy99 ---------------------------------------MTVVDDNYTGH
MAV_3136|M.avium_104 ---------------------------------MAAMTASVVPSDNYTGH
Mb1663c|M.bovis_AF2122/97 MLCARTDNHQGTGNVVTSAHMTRANDDDAGAAGIGAVAHMTTVDDNYTGH
Rv1637c|M.tuberculosis_H37Rv MLCARTDNHQGTGNVVTSAHMTRANDDDAGAAGIGAVAHMTTVDDNYTGH
MLBr_01391|M.leprae_Br4923 ------------------------------------MTASIDPVNDYTGH
MSMEG_3810|M.smegmatis_MC2_155 -------------------------------MTPSETPSSITVDDTYTGH
MAB_2314c|M.abscessus_ATCC_199 -------------------------------------MTSITIDDDYSGH
: *:**
Mflv_3549|M.gilvum_PYR-GCK VEPRT-AARRVLPGASIVKASVGPMDNNAYLVTCSQTGETLLIDAANDAA
Mvan_3340|M.vanbaalenii_PYR-1 VEPRT-AARRILPGASIVKVSVGPMDNDAYLVTCSRTGETLLIDAANDSA
TH_1580|M.thermoresistible__bu VEPQT-AARRTLPGASIIKVSVGPMDNNAYLITCSRTGETLLIDAANDAE
MMAR_2442|M.marinum_M VDPGT-VARRTLPGATILKASVGPMDNNAYLVTCSATGQTLLIDAANDAE
MUL_1621|M.ulcerans_Agy99 VDPGT-VARRTLPGATILKASVGPVDNNAYLVTCSATGQTLLIDAANDAE
MAV_3136|M.avium_104 VDPGT-AARRTLPGATIIKASVGPMDNNAYLVTCSATGETLLIDAANDAD
Mb1663c|M.bovis_AF2122/97 VERGK-AARRFLPGATILKASVGPMDNNAYLVTCSATGETLLIDAANDAE
Rv1637c|M.tuberculosis_H37Rv VERGK-AARRFLPGATILKASVGPMDNNAYLVTCSATGETLLIDAANDAE
MLBr_01391|M.leprae_Br4923 VDPGT-AARRALPGATILKVSVGPMDNNAYLVTCSATGETLLIDAANDAE
MSMEG_3810|M.smegmatis_MC2_155 VEPGT-AARRTLADATIVKASVGPMDNNCYLVTCRSTGETLLIDAANDAE
MAB_2314c|M.abscessus_ATCC_199 VEPGSGVARRSVDGATIIKASVGPMDNNAYIVTCTKTGKSLLIDAANDAE
*: . .*** : .*:*:*.****:**:.*::** **::********:
Mflv_3549|M.gilvum_PYR-GCK LLLELIERYAPTLSLIVTSHQHQDHWLALEEVVAATGAPTAAHSLDAGPL
Mvan_3340|M.vanbaalenii_PYR-1 VLLELIERYAPKLSLIVTSHQHQDHWLALEDVVAATGAPTAAHSLDAGPL
TH_1580|M.thermoresistible__bu ILLDLIERYAPKLSLIVTSHQHFDHWQALEKVVAATGAPTAAHHLDAEPL
MMAR_2442|M.marinum_M VLIDLIRRYAPKIALIVTSHQHFDHWQALQAVAEATGAPTAAHEIDAEPL
MUL_1621|M.ulcerans_Agy99 VLIDLIRRYAPKIALIVTSHQHFDHWQALQAVAEATGAPTAAHEIDAEPL
MAV_3136|M.avium_104 VLIGLIRDYAPKLSLIVTSHQHFDHWQALADVAAATGAPTAANEIDADPL
Mb1663c|M.bovis_AF2122/97 VLIDLVRRYAPKLALIVTSHQHFDHWQALQAVAAATGAPTAAHPIDADPL
Rv1637c|M.tuberculosis_H37Rv VLIDLVRRYAPKLALIVTSHQHFDHWQALQAVAAATGAPTAAHPIDADPL
MLBr_01391|M.leprae_Br4923 VLIDLVQRYAPKLSLIVTSHQHFDHWQALEAVVAATGAPTAVHELDAEPL
MSMEG_3810|M.smegmatis_MC2_155 VIIGLVEQHAPKVSLIVTTHQHQDHWLALQAVTEATGAPTAAHALDAGAL
MAB_2314c|M.abscessus_ATCC_199 RLATLVDESAPNIELIVTTHQHFDHWQALEAIVGKTQSPSAAHDLDAGPL
: *: **.: ****:*** *** ** :. * :*:*.: :** .*
Mflv_3549|M.gilvum_PYR-GCK PVTPDRLLSGGDTVTVGALNFDVIHLRGHTPGSVALALGGPATD----DR
Mvan_3340|M.vanbaalenii_PYR-1 PVTPDRLLADGDTVTIGDLNFDVIHLRGHTPGSVALALSGPATD----GR
TH_1580|M.thermoresistible__bu PVPPDRILSGGETITIGDLHFDVIHLRGHTPGSVALALSGPPAG----HT
MMAR_2442|M.marinum_M PVKPDRLLANGDRVQIGELSFDVIHLRGHTPGSIALALDGAATG----GV
MUL_1621|M.ulcerans_Agy99 PVKPDRLLANGDRVQIGELSFDVIHLRGHTPGSIALALDGAATG----GV
MAV_3136|M.avium_104 PVKPDRLLAGGDTVRIGELAFDVIHLRGHTPGSIALALDGAATG----GV
Mb1663c|M.bovis_AF2122/97 PVKPDRLLTHGDSVRIGELTFDVIHLRGHTPGSIALALGGPVTG----GV
Rv1637c|M.tuberculosis_H37Rv PVKPDRLLTHGDSVRIGELTFDVIHLRGHTPGSIALALGGPVTG----GV
MLBr_01391|M.leprae_Br4923 PVRPDRLLTNGDCVQIGELTFDVIHLRGHTPGSIALALDGATSGPKTGRV
MSMEG_3810|M.smegmatis_MC2_155 PVKPDRILSDGDKITVGNLTFDAIHLQGHTPGSVALALAGADGAD---GP
MAB_2314c|M.abscessus_ATCC_199 PVRPNTLLAGGDSLDIGDLHFDVIHLRGHTPGSVALAFT--AAG-----V
** *: :*: *: : :* * **.***:******:***:
Mflv_3549|M.gilvum_PYR-GCK VHLFTGDCLFPGGVGKTWKEGDFEQLLGDVSSRVFDVFPDQTVVYPGHGD
Mvan_3340|M.vanbaalenii_PYR-1 VHLFTGDCLFPGGVGKTWREGDFEQLLGDVTSRVFDVFGDDTVVYPGHGD
TH_1580|M.thermoresistible__bu THLFTGDCLFPGGVGKTWEPGAFEQLLDDVITRVFDVYPDSTVVYPGHGD
MMAR_2442|M.marinum_M TQLFTGDCLFPGGVGKTWQPGDFTQLVEDVSSRVFDVYPDSTVVYPGHGD
MUL_1621|M.ulcerans_Agy99 TQLFTGDCLFPGGVGKTWQPGDFTQLVEDVSSRVFNVYPDSTVVYPGHGD
MAV_3136|M.avium_104 TQLFTGDCLFPGGVGKTWQPGDFDQLIDDVTTRVFDVYDDSTVVYPGHGD
Mb1663c|M.bovis_AF2122/97 TQLFTGDCLFPGGVGKTWQPADFTQLLDDVTTRVFDVYADSTVIYPGHGD
Rv1637c|M.tuberculosis_H37Rv TQLFTGDCLFPGGVGKTWQPADFTQLLDDVTTRVFDVYADSTVIYPGHGD
MLBr_01391|M.leprae_Br4923 TQLFTGDCLFPGGVGKTWQRSDFTQLLDDVTTRVFDVYADTTAIYPGHGD
MSMEG_3810|M.smegmatis_MC2_155 THLFTGDCLFPGGVGKTWKPGDFETLLGDVTTKVFDVYDDRTVVYPGHGD
MAB_2314c|M.abscessus_ATCC_199 THLFTGDSLFPGGPGRTTNPEEFTSLMDDLEGLVFGRYPDDTVVYPGHGD
.:*****.***** *:* . * *: *: **. : * *.:******
Mflv_3549|M.gilvum_PYR-GCK DTTLGTERPHLGEWRERGW
Mvan_3340|M.vanbaalenii_PYR-1 DTTLGTERPHLGEWHERGW
TH_1580|M.thermoresistible__bu DTTLGAERPHLGEWRERGW
MMAR_2442|M.marinum_M DTVLGVERPHLDEWRERGW
MUL_1621|M.ulcerans_Agy99 DTALGFERPHLDEWRERGW
MAV_3136|M.avium_104 DTVLGNERPHLSEWRERGW
Mb1663c|M.bovis_AF2122/97 DTELGAERPSLSEWRARGW
Rv1637c|M.tuberculosis_H37Rv DTELGAERPSLSEWRARGW
MLBr_01391|M.leprae_Br4923 DTVLGAERPSLAEWRERGW
MSMEG_3810|M.smegmatis_MC2_155 DTTLGAERPSLAEWRERGW
MAB_2314c|M.abscessus_ATCC_199 DTTLGSERPHLAEWRKRGW
** ** *** * **: ***