For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_2314c (-)

annotation: Beta-lactamase-like
coordinates: 2366013 - 2366690
length: 225

TSITIDDDYSGHVEPGSGVARRSVDGATIIKASVGPMDNNAYIVTCTKTGKSLLIDAANDAERLATLVDE
SAPNIELIVTTHQHFDHWQALEAIVGKTQSPSAAHDLDAGPLPVRPNTLLAGGDSLDIGDLHFDVIHLRG
HTPGSVALAFTAAGVTHLFTGDSLFPGGPGRTTNPEEFTSLMDDLEGLVFGRYPDDTVVYPGHGDDTTLG
SERPHLAEWRKRGW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2314c--100% (225)Beta-lactamase-like
M. abscessus ATCC 19977MAB_4755c-2e-2131.60% (212) hypothetical protein MAB_4755c
M. abscessus ATCC 19977MAB_2873c-1e-1329.13% (206) hypothetical protein MAB_2873c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1663c-2e-8365.18% (224) hypothetical protein Mb1663c
M. gilvum PYR-GCKMflv_3549-3e-8163.51% (222) beta-lactamase domain-containing protein
M. tuberculosis H37RvRv1637c-2e-8365.18% (224) hypothetical protein Rv1637c
M. leprae Br4923MLBr_01391-2e-8263.48% (230) hypothetical protein MLBr_01391
M. marinum MMMAR_2442-2e-8666.82% (223) hypothetical protein MMAR_2442
M. avium 104MAV_3136-1e-8364.16% (226) hydrolase
M. smegmatis MC2 155MSMEG_3810-4e-8263.16% (228) hydrolase
M. thermoresistible (build 8)TH_1580-1e-8565.47% (223) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1621-2e-8666.37% (223) hypothetical protein MUL_1621
M. vanbaalenii PYR-1Mvan_3340-3e-8062.78% (223) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2442|M.marinum_M               ---------------------------------------MTVVDDNYTGH
MUL_1621|M.ulcerans_Agy99           ---------------------------------------MTVVDDNYTGH
MAV_3136|M.avium_104                ---------------------------------MAAMTASVVPSDNYTGH
Mb1663c|M.bovis_AF2122/97           MLCARTDNHQGTGNVVTSAHMTRANDDDAGAAGIGAVAHMTTVDDNYTGH
Rv1637c|M.tuberculosis_H37Rv        MLCARTDNHQGTGNVVTSAHMTRANDDDAGAAGIGAVAHMTTVDDNYTGH
MLBr_01391|M.leprae_Br4923          ------------------------------------MTASIDPVNDYTGH
Mflv_3549|M.gilvum_PYR-GCK          ---------------------------------------MTAADDNYTGH
Mvan_3340|M.vanbaalenii_PYR-1       ---------------------------------------MTVVDDNYTGH
TH_1580|M.thermoresistible__bu      ---------------------------------------MTVVAEEYTGH
MSMEG_3810|M.smegmatis_MC2_155      -------------------------------MTPSETPSSITVDDTYTGH
MAB_2314c|M.abscessus_ATCC_199      -------------------------------------MTSITIDDDYSGH
                                                                                : *:**

MMAR_2442|M.marinum_M               VDPGT-VARRTLPGATILKASVGPMDNNAYLVTCSATGQTLLIDAANDAE
MUL_1621|M.ulcerans_Agy99           VDPGT-VARRTLPGATILKASVGPVDNNAYLVTCSATGQTLLIDAANDAE
MAV_3136|M.avium_104                VDPGT-AARRTLPGATIIKASVGPMDNNAYLVTCSATGETLLIDAANDAD
Mb1663c|M.bovis_AF2122/97           VERGK-AARRFLPGATILKASVGPMDNNAYLVTCSATGETLLIDAANDAE
Rv1637c|M.tuberculosis_H37Rv        VERGK-AARRFLPGATILKASVGPMDNNAYLVTCSATGETLLIDAANDAE
MLBr_01391|M.leprae_Br4923          VDPGT-AARRALPGATILKVSVGPMDNNAYLVTCSATGETLLIDAANDAE
Mflv_3549|M.gilvum_PYR-GCK          VEPRT-AARRVLPGASIVKASVGPMDNNAYLVTCSQTGETLLIDAANDAA
Mvan_3340|M.vanbaalenii_PYR-1       VEPRT-AARRILPGASIVKVSVGPMDNDAYLVTCSRTGETLLIDAANDSA
TH_1580|M.thermoresistible__bu      VEPQT-AARRTLPGASIIKVSVGPMDNNAYLITCSRTGETLLIDAANDAE
MSMEG_3810|M.smegmatis_MC2_155      VEPGT-AARRTLADATIVKASVGPMDNNCYLVTCRSTGETLLIDAANDAE
MAB_2314c|M.abscessus_ATCC_199      VEPGSGVARRSVDGATIIKASVGPMDNNAYIVTCTKTGKSLLIDAANDAE
                                    *:  . .*** : .*:*:*.****:**:.*::**  **::********: 

MMAR_2442|M.marinum_M               VLIDLIRRYAPKIALIVTSHQHFDHWQALQAVAEATGAPTAAHEIDAEPL
MUL_1621|M.ulcerans_Agy99           VLIDLIRRYAPKIALIVTSHQHFDHWQALQAVAEATGAPTAAHEIDAEPL
MAV_3136|M.avium_104                VLIGLIRDYAPKLSLIVTSHQHFDHWQALADVAAATGAPTAANEIDADPL
Mb1663c|M.bovis_AF2122/97           VLIDLVRRYAPKLALIVTSHQHFDHWQALQAVAAATGAPTAAHPIDADPL
Rv1637c|M.tuberculosis_H37Rv        VLIDLVRRYAPKLALIVTSHQHFDHWQALQAVAAATGAPTAAHPIDADPL
MLBr_01391|M.leprae_Br4923          VLIDLVQRYAPKLSLIVTSHQHFDHWQALEAVVAATGAPTAVHELDAEPL
Mflv_3549|M.gilvum_PYR-GCK          LLLELIERYAPTLSLIVTSHQHQDHWLALEEVVAATGAPTAAHSLDAGPL
Mvan_3340|M.vanbaalenii_PYR-1       VLLELIERYAPKLSLIVTSHQHQDHWLALEDVVAATGAPTAAHSLDAGPL
TH_1580|M.thermoresistible__bu      ILLDLIERYAPKLSLIVTSHQHFDHWQALEKVVAATGAPTAAHHLDAEPL
MSMEG_3810|M.smegmatis_MC2_155      VIIGLVEQHAPKVSLIVTTHQHQDHWLALQAVTEATGAPTAAHALDAGAL
MAB_2314c|M.abscessus_ATCC_199      RLATLVDESAPNIELIVTTHQHFDHWQALEAIVGKTQSPSAAHDLDAGPL
                                     :  *:   **.: ****:*** *** **  :.  * :*:*.: :** .*

MMAR_2442|M.marinum_M               PVKPDRLLANGDRVQIGELSFDVIHLRGHTPGSIALALDGAATG----GV
MUL_1621|M.ulcerans_Agy99           PVKPDRLLANGDRVQIGELSFDVIHLRGHTPGSIALALDGAATG----GV
MAV_3136|M.avium_104                PVKPDRLLAGGDTVRIGELAFDVIHLRGHTPGSIALALDGAATG----GV
Mb1663c|M.bovis_AF2122/97           PVKPDRLLTHGDSVRIGELTFDVIHLRGHTPGSIALALGGPVTG----GV
Rv1637c|M.tuberculosis_H37Rv        PVKPDRLLTHGDSVRIGELTFDVIHLRGHTPGSIALALGGPVTG----GV
MLBr_01391|M.leprae_Br4923          PVRPDRLLTNGDCVQIGELTFDVIHLRGHTPGSIALALDGATSGPKTGRV
Mflv_3549|M.gilvum_PYR-GCK          PVTPDRLLSGGDTVTVGALNFDVIHLRGHTPGSVALALGGPATD----DR
Mvan_3340|M.vanbaalenii_PYR-1       PVTPDRLLADGDTVTIGDLNFDVIHLRGHTPGSVALALSGPATD----GR
TH_1580|M.thermoresistible__bu      PVPPDRILSGGETITIGDLHFDVIHLRGHTPGSVALALSGPPAG----HT
MSMEG_3810|M.smegmatis_MC2_155      PVKPDRILSDGDKITVGNLTFDAIHLQGHTPGSVALALAGADGAD---GP
MAB_2314c|M.abscessus_ATCC_199      PVRPNTLLAGGDSLDIGDLHFDVIHLRGHTPGSVALAFT--AAG-----V
                                    ** *: :*: *: : :* * **.***:******:***:            

MMAR_2442|M.marinum_M               TQLFTGDCLFPGGVGKTWQPGDFTQLVEDVSSRVFDVYPDSTVVYPGHGD
MUL_1621|M.ulcerans_Agy99           TQLFTGDCLFPGGVGKTWQPGDFTQLVEDVSSRVFNVYPDSTVVYPGHGD
MAV_3136|M.avium_104                TQLFTGDCLFPGGVGKTWQPGDFDQLIDDVTTRVFDVYDDSTVVYPGHGD
Mb1663c|M.bovis_AF2122/97           TQLFTGDCLFPGGVGKTWQPADFTQLLDDVTTRVFDVYADSTVIYPGHGD
Rv1637c|M.tuberculosis_H37Rv        TQLFTGDCLFPGGVGKTWQPADFTQLLDDVTTRVFDVYADSTVIYPGHGD
MLBr_01391|M.leprae_Br4923          TQLFTGDCLFPGGVGKTWQRSDFTQLLDDVTTRVFDVYADTTAIYPGHGD
Mflv_3549|M.gilvum_PYR-GCK          VHLFTGDCLFPGGVGKTWKEGDFEQLLGDVSSRVFDVFPDQTVVYPGHGD
Mvan_3340|M.vanbaalenii_PYR-1       VHLFTGDCLFPGGVGKTWREGDFEQLLGDVTSRVFDVFGDDTVVYPGHGD
TH_1580|M.thermoresistible__bu      THLFTGDCLFPGGVGKTWEPGAFEQLLDDVITRVFDVYPDSTVVYPGHGD
MSMEG_3810|M.smegmatis_MC2_155      THLFTGDCLFPGGVGKTWKPGDFETLLGDVTTKVFDVYDDRTVVYPGHGD
MAB_2314c|M.abscessus_ATCC_199      THLFTGDSLFPGGPGRTTNPEEFTSLMDDLEGLVFGRYPDDTVVYPGHGD
                                    .:*****.***** *:* .   *  *: *:   **. : * *.:******

MMAR_2442|M.marinum_M               DTVLGVERPHLDEWRERGW
MUL_1621|M.ulcerans_Agy99           DTALGFERPHLDEWRERGW
MAV_3136|M.avium_104                DTVLGNERPHLSEWRERGW
Mb1663c|M.bovis_AF2122/97           DTELGAERPSLSEWRARGW
Rv1637c|M.tuberculosis_H37Rv        DTELGAERPSLSEWRARGW
MLBr_01391|M.leprae_Br4923          DTVLGAERPSLAEWRERGW
Mflv_3549|M.gilvum_PYR-GCK          DTTLGTERPHLGEWRERGW
Mvan_3340|M.vanbaalenii_PYR-1       DTTLGTERPHLGEWHERGW
TH_1580|M.thermoresistible__bu      DTTLGAERPHLGEWRERGW
MSMEG_3810|M.smegmatis_MC2_155      DTTLGAERPSLAEWRERGW
MAB_2314c|M.abscessus_ATCC_199      DTTLGSERPHLAEWRKRGW
                                    ** ** *** * **: ***