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TDNDGVRLQKVLSQAGIASRRVAEKMIRDGRVEVDDRIVTELGTRVDPAESVIRVDGARITVDDTLVHLA INKPRGMHSTMSDDRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDGELAHRLMHPSYEVPKS YVATVLGSVPRGLGRKLREGVELDDGPVQVDDFALVDTTPGRTLVRVTLHEGRKHIVRRLLAEVGFPVQN LVRTDIGGVSLGDQRPGSIRALTQKEIGELYKAVGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3495 | - | - | 100% (247) | pseudouridine synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1738 | - | 1e-111 | 79.75% (242) | hypothetical protein Mb1738 |
| M. tuberculosis H37Rv | Rv1711 | - | 1e-111 | 79.75% (242) | hypothetical protein Rv1711 |
| M. leprae Br4923 | MLBr_01370 | - | 1e-106 | 76.76% (241) | putative pseudouridine synthase |
| M. abscessus ATCC 19977 | MAB_2370 | - | 3e-96 | 69.96% (243) | l RNA pseudouridine synthase |
| M. marinum M | MMAR_2526 | - | 1e-111 | 77.08% (253) | pseudouridylate synthase |
| M. avium 104 | MAV_3065 | - | 1e-108 | 75.30% (247) | ribosomal large subunit pseudouridine synthase B |
| M. smegmatis MC2 155 | MSMEG_3740 | rluB | 1e-118 | 83.81% (247) | ribosomal large subunit pseudouridine synthase B |
| M. thermoresistible (build 8) | TH_0200 | - | 1e-119 | 84.21% (247) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3234 | - | 1e-112 | 77.08% (253) | pseudouridylate synthase |
| M. vanbaalenii PYR-1 | Mvan_3276 | - | 1e-133 | 95.55% (247) | pseudouridine synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3495|M.gilvum_PYR-GCK -----MTDND-----------GVRLQKVLSQAGIASRRVAEKMIRDGRVE
Mvan_3276|M.vanbaalenii_PYR-1 -----MTDND-----------GIRLQKVLSQAGIASRRVAEKMIRDGRVE
TH_0200|M.thermoresistible__bu -----MADQD-----------GVRLQKVLSQAGVASRRVAEQMIREGRVE
MSMEG_3740|M.smegmatis_MC2_155 -----MAEEQ-----------GVRLQKVLSQAGIASRRVAERMIIDGRVE
MMAR_2526|M.marinum_M -----MTDTEDFEQER-----GIRLQKVLSQAGIASRRAAEKLIIDGRVE
MUL_3234|M.ulcerans_Agy99 -----MTDTEDFEQER-----GIRLQKVLSQAGIASRRAAEKLIIDGRVE
Mb1738|M.bovis_AF2122/97 ----MMAEPEESREPR-----GIRLQKVLSQAGIASRRAAEKMIVDGRVE
Rv1711|M.tuberculosis_H37Rv ----MMAEPEESREPR-----GIRLQKVLSQAGIASRRAAEKMIVDGRVE
MAV_3065|M.avium_104 ----MMVEAQ-----------GIRLQKVLSQAGIASRRAAEKLIVDGRVE
MLBr_01370|M.leprae_Br4923 ----MMVEIHDSRMDRGAG--AVRLQKILSRAGIASRRAAEKLIIEGRVE
MAB_2370|M.abscessus_ATCC_1997 MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVE
* .:****:**:**:****.**::* :****
Mflv_3495|M.gilvum_PYR-GCK VDDRIVTELGTRVDPAESVIRVDGARITVDDTLVHLAINKPRGMHSTMSD
Mvan_3276|M.vanbaalenii_PYR-1 VDGRIVTELGTRVDPAASVIRVDGARITVDDTLVYLAINKPRGMHSTMSD
TH_0200|M.thermoresistible__bu VDGRIVTELGTRVDPDTAEIRVDGMRIVLDDTMVYLAINKPRGMHSTMSD
MSMEG_3740|M.smegmatis_MC2_155 VDGQIVTELGTRVDPAVADIRVDGSRIILDDTMVYLAINKPRGMHSTMSD
MMAR_2526|M.marinum_M VDGQVVTELGTRVDPDTSLIRVDGVRVILDDSLVYLALNKPRGMHSTMSD
MUL_3234|M.ulcerans_Agy99 VDGQVVTELGTRVDPDTSLIRVDGVRVILDDSLVYLALNKPRGMHSTMSD
Mb1738|M.bovis_AF2122/97 VDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSD
Rv1711|M.tuberculosis_H37Rv VDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSD
MAV_3065|M.avium_104 VDGQVVTELGTRVDPDAAVIRVDGARVVLDESQVYLALNKPRGVHSTMSD
MLBr_01370|M.leprae_Br4923 VDGQLVRELGTRVDPDVSVVRVDGVKVVVDDSLVYLALNKPRGMYSTMSD
MAB_2370|M.abscessus_ATCC_1997 VDGEIVTEQGRRIDPAVNVVRVDGARVIMNTDLVYLALNKPFGMLSTMSD
**..:* * * *:** :**** :: :: *:**:*** *: *****
Mflv_3495|M.gilvum_PYR-GCK DRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDGELAHRLMHP
Mvan_3276|M.vanbaalenii_PYR-1 DRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDGELAHRLMHP
TH_0200|M.thermoresistible__bu DRGRPCIGDLVEHRVRGNKNLFHVGRLDADTEGLMLLTNDGELAHRLMHP
MSMEG_3740|M.smegmatis_MC2_155 DRGRPCVGDLVEHRVRGNKKLFHVGRLDADTEGLLLLTNDGELAHRLMHP
MMAR_2526|M.marinum_M DRGRPCIGDLIERKVRGNKNLFHVGRLDADTEGLILLTNDGELAHRLMHP
MUL_3234|M.ulcerans_Agy99 DRGRPCIGDLIERKVRGNKNLFHVGRLDADTEGLILLTNDGELAHRLMHP
Mb1738|M.bovis_AF2122/97 DRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHP
Rv1711|M.tuberculosis_H37Rv DRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHP
MAV_3065|M.avium_104 DRGRPCIGDLIERRVRGNKNLFHVGRLDAETEGLILLTNDGELAHRLMHP
MLBr_01370|M.leprae_Br4923 DRGRPCVGDLIERRVRGNKKLFHVGRLDADTEGLILLTNDGELAHRLMHP
MAB_2370|M.abscessus_ATCC_1997 DRGRPCVGKLIEERVRGNQGVRNVGRLDADTVGLILLTNDGELTHRLMHP
******:*.*:*.:***.: : :******:* **:********:******
Mflv_3495|M.gilvum_PYR-GCK SYEVPKSYVATVLGSVPRGLGRKLREGVELDDGPVQVDDFALVDTTPGRT
Mvan_3276|M.vanbaalenii_PYR-1 SFEVPKSYVATVLGSVPKGLGRKLREGVELEDGPVQVDDFAVVDTTPGRT
TH_0200|M.thermoresistible__bu SFEVPKTYVATVHGSVPRNLGRRLREGVELKDGPARVDDFAVVAAVPGKT
MSMEG_3740|M.smegmatis_MC2_155 SFEVPKTYVATVMGTVPRGLGKKLKAGVELDDGPAHVDDFAVVDTVPGKT
MMAR_2526|M.marinum_M SHEVPKTYLATVAGTVPRGLGKKLRAGIELEDGPVRVDGFAVVDAIPGKT
MUL_3234|M.ulcerans_Agy99 SHEVPKTYLATVAGTVPRGLGKKLRAGIELEDGPVRVDGFAVVDAIPGKT
Mb1738|M.bovis_AF2122/97 SHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKT
Rv1711|M.tuberculosis_H37Rv SHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKT
MAV_3065|M.avium_104 SHEVPKTYLATVTGSIPRGLGKTLRAGIELDDGMARVDEFAVVDAIPGKT
MLBr_01370|M.leprae_Br4923 SHEVSKTYLATVKGAVPRGLGKKLSVGLELDDGPAHVDDFAVVDAIPGKT
MAB_2370|M.abscessus_ATCC_1997 SYEVPKTYIATVAGTIPRGLGRQLRDGVELADGPAKVDEFKFLGTTDGQS
*.**.*:*:*** *::*:.**: * *:** ** . ** * .: : *::
Mflv_3495|M.gilvum_PYR-GCK LVRVTLHEGRKHIVRRLLAEVGFPVQNLVRTDIGGVSLGDQRPGSIRALT
Mvan_3276|M.vanbaalenii_PYR-1 LVRVTLHEGRKHIVRRLLAEVGFPVQELVRTDIGTVSLGDQRPGSIRVLT
TH_0200|M.thermoresistible__bu MVRVTLHEGRKRIVRRLLAAVGFPVQDLVRTDIGAVTLGDQRPGSIRALT
MSMEG_3740|M.smegmatis_MC2_155 MVKVTLHEGRNRIVRRLLAAVDFPVQELVRTEIGSVSLGDQRPGSIRALT
MMAR_2526|M.marinum_M LVRVTLHEGRNRIVRRMLAAVGFPVQALVRIDIGGVSLGEQRPGSVRALR
MUL_3234|M.ulcerans_Agy99 LVRVTLHEGRNRIVRRMLAAVGFPVQALVRIDIGGVSLGEQRPGSVRALR
Mb1738|M.bovis_AF2122/97 LVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR
Rv1711|M.tuberculosis_H37Rv LVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALR
MAV_3065|M.avium_104 LVRVTLHEGRNRIVRRLLAAAGFPVESLVRTDIGPISLGKQRPGSIRALG
MLBr_01370|M.leprae_Br4923 LVRLTLHEGRKRIVRRLLTAAGFPVEMLVRTDIGAVSLGDQRPGCLRALL
MAB_2370|M.abscessus_ATCC_1997 MVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGNQRPGSLRALG
:*::******::****:: ...** *** .** ::**.****.:*.*
Mflv_3495|M.gilvum_PYR-GCK QKEIGELYKAVGL
Mvan_3276|M.vanbaalenii_PYR-1 QKEIGELYKAVGL
TH_0200|M.thermoresistible__bu RKEVGELYKAVGL
MSMEG_3740|M.smegmatis_MC2_155 RKEVGELYQAVGL
MMAR_2526|M.marinum_M RDEIGQLYKAVGL
MUL_3234|M.ulcerans_Agy99 RDEIGQLYKAVGL
Mb1738|M.bovis_AF2122/97 SNEIGQLYQAVGL
Rv1711|M.tuberculosis_H37Rv SNEIGQLYQAVGL
MAV_3065|M.avium_104 RDEVGRLYQAVGL
MLBr_01370|M.leprae_Br4923 RDEIRQLYKEVGL
MAB_2370|M.abscessus_ATCC_1997 RDEIGSLYKAVGL
.*: **: ***