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TVVEFLVEPLQLEFMVRATVTTLIASTVCATLSCWLVLIGWSLMGDAVSHAVLPGVVLAHIVGAPFALGA IIFGFVAVGLIGVVRDTSRTKEDAAIGVVFTTLFALGLVLISVTPSQVDLNHIIFGNVLGVSRADLIQVA VLGTVVMAVLVYKRRDFTLYAFDPHHAHAIGLNPRLLGAALLGLLALTAVVALQAVGVVLVVALLITPGA TAYLITERFSRMLLIAPTIAAVCALTGLYASYYLDTASGPMVVLANGTAFALAYLARLGREQRTRHHRPG VRAPWTETPAAEDASDCRRSRRAGLPRRCGRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3166 | - | - | 100% (314) | ABC-3 protein |
| M. gilvum PYR-GCK | Mflv_1456 | - | 7e-20 | 29.69% (229) | ABC-3 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2086 | - | 2e-07 | 30.15% (136) | integral membrane protein |
| M. tuberculosis H37Rv | Rv2060 | - | 2e-07 | 30.15% (136) | integral membrane protein |
| M. leprae Br4923 | MLBr_00335 | - | 2e-18 | 27.63% (257) | putative ABC-transporter transmembrane protein |
| M. abscessus ATCC 19977 | MAB_0575c | - | 5e-23 | 30.89% (259) | ABC transporter transmembrane protein |
| M. marinum M | MMAR_5073 | - | 5e-20 | 26.82% (261) | permease component of an ABC-type transporter |
| M. avium 104 | MAV_0581 | - | 3e-20 | 29.17% (264) | ABC-type Mn2+/Zn2+ transport system, permease component |
| M. smegmatis MC2 155 | MSMEG_6045 | - | 1e-19 | 26.64% (229) | ABC heavy metal transporter, inner membrane subunit |
| M. thermoresistible (build 8) | TH_4073 | - | 1e-112 | 67.31% (309) | PUTATIVE ABC-3 protein |
| M. ulcerans Agy99 | MUL_4149 | - | 5e-20 | 26.44% (261) | permease component of an ABC-type transporter |
| M. vanbaalenii PYR-1 | Mvan_3369 | - | 1e-123 | 83.83% (266) | ABC-3 protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5073|M.marinum_M MTNDRLVDMLDHLFAFDITAHLLRHDFVQQALIAAALLGLVAGLIGPFVV
MUL_4149|M.ulcerans_Agy99 MTNDRLVDILDHLFAFDITAHLLRHDFVQQALIAAALLGLVAGLIGPFVV
Mb2086|M.bovis_AF2122/97 --------------------------------------------------
Rv2060|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00335|M.leprae_Br4923 -MDDRLAHMWNHLFSFDITTHLLSHNFVQQALLAALLLGLVAGLIGPFIV
MAV_0581|M.avium_104 -MEHRLADMADHLFSFDITVHLLGHDFVQQALVAAALLGLVAGLIGPFIV
MAB_0575c|M.abscessus_ATCC_199 ---------MNNFFDLSLTADLLGRDFVQQAILAAALLGLLAGLIGPFVV
MSMEG_6045|M.smegmatis_MC2_155 MPPGDLAQTYLAIGYQHNWLHILGSAFMRNALIGGTLVALAAGLIGYFII
Mflv_3166|M.gilvum_PYR-GCK -----------MTVV-EFLVEPLQLEFMVRATVTTLIASTVCATLSCWLV
Mvan_3369|M.vanbaalenii_PYR-1 -----------MSVL-EFLIEPMRLDFMVRATATTLVASVVCATLSCWLV
TH_4073|M.thermoresistible__bu -----------MTLLREILIDPLAYEFMVRALATALITSVVCALLSCWLV
MMAR_5073|M.marinum_M MRQMSFAVHGSSELSLTGAAFALLSGLPVGVGALVGSALAAALFGILGQR
MUL_4149|M.ulcerans_Agy99 MRQMSFAVHGSSELSLTGAAFALLSGLPVGVGALVGSALAAALFGILGQR
Mb2086|M.bovis_AF2122/97 --------------------------------------------------
Rv2060|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00335|M.leprae_Br4923 MRQMSFAVHGSSELSLTGATFALLAGFEMGVGALVGSALAATLFGILGRR
MAV_0581|M.avium_104 MRQMSFAVHGSSELSLTGAAFALLVGIGVGVGALIGSALAAALFGVLGRR
MAB_0575c|M.abscessus_ATCC_199 MRQMSFAVHGSSELSLTGAAAALLAGANVGTGALLGSVVAAILFGVLGQR
MSMEG_6045|M.smegmatis_MC2_155 VRNTAFAAHALAHIGLPGATGAALLGLPAVLGLGVFCVAGAVVIGALGKQ
Mflv_3166|M.gilvum_PYR-GCK LIGWSLMGDAVSHAVLPGVVLAHIVGAPFALGAIIFGFVAVGLIGVVRDT
Mvan_3369|M.vanbaalenii_PYR-1 LIGWSLMGDAVSHAVLPGVVLAYIVGAPFALGAVIFGFAAVALIGIVRGT
TH_4073|M.thermoresistible__bu LIGWSLMGDAVSHAVLPGVVLAYIVGAPFAVGAVVFGFLAVALIGLVRDT
MMAR_5073|M.marinum_M ARERD-SVIGVVLAFGMGLAVLFIHLYPGRTGTSFALLTGQIVGVGYSGL
MUL_4149|M.ulcerans_Agy99 ARERD-SVIGVVLAFGMGLAVLFIHLYPGRTGTSFALLTGQIVGVGYSGL
Mb2086|M.bovis_AF2122/97 --------------------------------------------------
Rv2060|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00335|M.leprae_Br4923 ARERD-SVIGVVLAFGLGLAVLFIHLYPGRTGTSLALLTGQIIDVGYSGL
MAV_0581|M.avium_104 ARERD-SVIGVVLAFGLGLAVLFIHLYPGRTATSFALLTGQIVGVGYTGL
MAB_0575c|M.abscessus_ATCC_199 TKDRD-SSIGVVMAFGLGLAVLFIHLYPGRTGTNFALLTGQIVGVGYSGL
MSMEG_6045|M.smegmatis_MC2_155 AHDRE-VATGTVLALATGFGLFFNSLATKNSSTLTNVLFGNLLAITHEQL
Mflv_3166|M.gilvum_PYR-GCK SRTKEDAAIGVVFTTLFALGLVLISVTPSQVDLN-HIIFGNVLGVSRADL
Mvan_3369|M.vanbaalenii_PYR-1 SRIKEDAAIGVVFTTLFALGLVLISVTPSQVDLN-HIIFGNLLGVSRADL
TH_4073|M.thermoresistible__bu SRVKEDAAIGIVFTTLFAAGLVLVSVTPSQVDLN-HIVFGNLLGVSRNDL
MMAR_5073|M.marinum_M TMLALICVLVVAALAICYRPLLFATVDPEVAAARGVPVRTLSIVFAALVG
MUL_4149|M.ulcerans_Agy99 TMLALICVLVVAALAICYRPLLFATVDPEVAAARGVPVRTLSIVFVALVG
Mb2086|M.bovis_AF2122/97 -MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMG
Rv2060|M.tuberculosis_H37Rv -MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMG
MLBr_00335|M.leprae_Br4923 ATLALVCLFVIAVLTTCYRPLLFATVDPEVAAACGVPVHALGIVFAALVG
MAV_0581|M.avium_104 TMLALVCLLVIAVLATCYRPLLFATVDPDVAAARGVPVHALGIVFAALVG
MAB_0575c|M.abscessus_ATCC_199 LMLVVVSMVVGAVLAVTYRPMLFATVDPDVAEARGVPVRALGIVFAALVG
MSMEG_6045|M.smegmatis_MC2_155 LTFTALLLVLAAAIVFIYRPLLFASVNAQVAEAKGVPVRTLSVVFMVLLG
Mflv_3166|M.gilvum_PYR-GCK IQVAVLGTVVMAVLVYKRRDFTLYAFDPHHAHAIGLNPRLLGAALLGLLA
Mvan_3369|M.vanbaalenii_PYR-1 TQVVVLGAVVLAVLVFKRRDFTLYAFDATHAHAIGLNPRLLGATLLGLLA
TH_4073|M.thermoresistible__bu LQVAILGAVVVAAVLAKRRDFTLYAFDSIHAHTIGLNPRLLGAALLALLA
.. : .: :.: * : : :.:. * : *: : *. .: *:.
MMAR_5073|M.marinum_M VVAAQAVQIVGALLVMSLLITPAAAAARVVTAPAAAILTSVVFAEVAAVG
MUL_4149|M.ulcerans_Agy99 VVAAQAVQIVGALLVMSLLITPAAAAARVVTAPAAAILTSVVFAELAAVG
Mb2086|M.bovis_AF2122/97 VVAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVG
Rv2060|M.tuberculosis_H37Rv VVAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVG
MLBr_00335|M.leprae_Br4923 LVAAQAVQVVGALLVMSLLITPAAAAAQVVASPVAAMVAAVIFAEVSAVG
MAV_0581|M.avium_104 VVAAQAVQIVGALLVMSLLITPAAAAARVVASPGAAMLASVAFAEVSALG
MAB_0575c|M.abscessus_ATCC_199 LTAAQGVQIVGALLVMSLLITPAAAAARITSSPARAIALSIVFAEIAAIG
MSMEG_6045|M.smegmatis_MC2_155 VAVTMAVQAVGTLLLFALVVTPAATAITLTAQPRLAMAISTVISLLSVWA
Mflv_3166|M.gilvum_PYR-GCK LTAVVALQAVGVVLVVALLITPGATAYLITERFSRMLLIAPTIAAVCALT
Mvan_3369|M.vanbaalenii_PYR-1 LTAVVALQAVGVVLVVALLITPGATAYLLTDRFQRMLLIAPATAVFAGLV
TH_4073|M.thermoresistible__bu LTAVAALQAVGVVLVVAMLIIPGATAYLLTDSFGRMLVIAPLMSVAAAIT
:... .:* **.:*:.:::: *.*:* :. : : : .
MMAR_5073|M.marinum_M GIVLSLAPGVPVSVFVATISFLIYLICRLLGRHR----------------
MUL_4149|M.ulcerans_Agy99 GIVLSLAPGVPVSVFVATISFLIYLICRLLGRHR----------------
Mb2086|M.bovis_AF2122/97 GILLSLAPGVPVSVFVATISFVIYLICWLLRRRR----------------
Rv2060|M.tuberculosis_H37Rv GILLSLAPGVPVSVFVATISFVIYLICWLLRRRR----------------
MLBr_00335|M.leprae_Br4923 GVVLSLAPGVPVSVFVATISFLIYLFCWLLGRHREVCA------------
MAV_0581|M.avium_104 GIVLSLAPGVPVSVFVATISFLIYLACWLIGRRREAAT------------
MAB_0575c|M.abscessus_ATCC_199 GIMLSLAPGVPISVFVTMIAVAIYLLCRLVGRYRHA--------------
MSMEG_6045|M.smegmatis_MC2_155 GLVLSAVFNLPPSFVIVTIACVFWFVVWAANRARRSAVARP---------
Mflv_3166|M.gilvum_PYR-GCK GLYASYYLDTASGPMVVLANGTAFALAYLARLGREQRTRHHRPGVRAPWT
Mvan_3369|M.vanbaalenii_PYR-1 GIYVSYYADTASGPMIVLANGVIFTLVYLLSP---------RHGLVTAWI
TH_4073|M.thermoresistible__bu GLYVSYHLDTASGGMIVVAQGLLFGLVYLFAPRQGVLTRAASARLRSRRS
*: * . . . .:. :
MMAR_5073|M.marinum_M --------------------------------------------------
MUL_4149|M.ulcerans_Agy99 --------------------------------------------------
Mb2086|M.bovis_AF2122/97 --------------------------------------------------
Rv2060|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00335|M.leprae_Br4923 --------------------------------------------------
MAV_0581|M.avium_104 --------------------------------------------------
MAB_0575c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6045|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3166|M.gilvum_PYR-GCK ET--------------------------------PAAEDASDCRRSRRAG
Mvan_3369|M.vanbaalenii_PYR-1 QK--------------------------------KTHAKSAGN-------
TH_4073|M.thermoresistible__bu PGDREHAEIANLGTTGSMETCSRRSVAARGPGGAPTSSTSAGSRPGRAAW
MMAR_5073|M.marinum_M ------------------------
MUL_4149|M.ulcerans_Agy99 ------------------------
Mb2086|M.bovis_AF2122/97 ------------------------
Rv2060|M.tuberculosis_H37Rv ------------------------
MLBr_00335|M.leprae_Br4923 ------------------------
MAV_0581|M.avium_104 ------------------------
MAB_0575c|M.abscessus_ATCC_199 ------------------------
MSMEG_6045|M.smegmatis_MC2_155 ------------------------
Mflv_3166|M.gilvum_PYR-GCK LPRRCGRRP---------------
Mvan_3369|M.vanbaalenii_PYR-1 ------------------------
TH_4073|M.thermoresistible__bu WTPRRRSPGWCRSSNGCATPIRTS