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M. tuberculosis H37Rv Rv2060 (-)

annotation: Possible conserved integral membrane protein
coordinates: 2316279 - 2316680
length: 133

MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMGVVAAQAVQIVGALLVMSLLIT
PAAAAARVVVAPVAAIATSVVFAEVSAVGGILLSLAPGVPVSVFVATISFVIYLICWLLRRRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2060--100% (133)Possible conserved integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2086-4e-67100.00% (133) integral membrane protein
M. gilvum PYR-GCKMflv_1456-2e-2239.53% (129) ABC-3 protein
M. leprae Br4923MLBr_00335-1e-5580.30% (132) putative ABC-transporter transmembrane protein
M. abscessus ATCC 19977MAB_0575c-3e-4871.43% (133) ABC transporter transmembrane protein
M. marinum MMMAR_5073-2e-5786.47% (133) permease component of an ABC-type transporter
M. avium 104MAV_0581-3e-5784.21% (133) ABC-type Mn2+/Zn2+ transport system, permease component
M. smegmatis MC2 155MSMEG_6045-3e-2543.70% (135) ABC heavy metal transporter, inner membrane subunit
M. thermoresistible (build 8)TH_1747-2e-5278.95% (133) Possible conserved integral membrane protein
M. ulcerans Agy99MUL_4149-1e-5684.96% (133) permease component of an ABC-type transporter
M. vanbaalenii PYR-1Mvan_5318-3e-2342.64% (129) ABC-3 protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv2060|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2086|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5073|M.marinum_M               MTNDRLVDMLDHLFAFDITAHLLRHDFVQQALIAAALLGLVAGLIGPFVV
MUL_4149|M.ulcerans_Agy99           MTNDRLVDILDHLFAFDITAHLLRHDFVQQALIAAALLGLVAGLIGPFVV
MLBr_00335|M.leprae_Br4923          -MDDRLAHMWNHLFSFDITTHLLSHNFVQQALLAALLLGLVAGLIGPFIV
MAV_0581|M.avium_104                -MEHRLADMADHLFSFDITVHLLGHDFVQQALVAAALLGLVAGLIGPFIV
MAB_0575c|M.abscessus_ATCC_199      ---------MNNFFDLSLTADLLGRDFVQQAILAAALLGLLAGLIGPFVV
TH_1747|M.thermoresistible__bu      -MNERLTELFRNLFAFDVTADLLGRSFVQQALLAAALLALVAGLIGPFIV
Mflv_1456|M.gilvum_PYR-GCK          MT-QTV----LAVGYQQNWVDIVGSLFMRNAWLGGTIVALAAGLMGYFIV
Mvan_5318|M.vanbaalenii_PYR-1       MT-QVLAVEYVALGYQDNWLHILGSSFMRNAWAGGTIVALAAGLMGYFIV
MSMEG_6045|M.smegmatis_MC2_155      MPPGDLAQTYLAIGYQHNWLHILGSAFMRNALIGGTLVALAAGLIGYFII
                                                                                      

Rv2060|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2086|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5073|M.marinum_M               MRQMSFAVHGSSELSLTGAAFALLSGLPVGVGALVGSALAAALFGILGQR
MUL_4149|M.ulcerans_Agy99           MRQMSFAVHGSSELSLTGAAFALLSGLPVGVGALVGSALAAALFGILGQR
MLBr_00335|M.leprae_Br4923          MRQMSFAVHGSSELSLTGATFALLAGFEMGVGALVGSALAATLFGILGRR
MAV_0581|M.avium_104                MRQMSFAVHGSSELSLTGAAFALLVGIGVGVGALIGSALAAALFGVLGRR
MAB_0575c|M.abscessus_ATCC_199      MRQMSFAVHGSSELSLTGAAAALLAGANVGTGALLGSVVAAILFGVLGQR
TH_1747|M.thermoresistible__bu      MRQMSFAVHGSSELSLTGAAFALLAGFNVGVGALIGCALAAVLFGVLGQR
Mflv_1456|M.gilvum_PYR-GCK          VRHSSFAAHALAHIGLPGATGAVLIGVPAAVGLGVFCVGGALVIGALGKR
Mvan_5318|M.vanbaalenii_PYR-1       VRHSSFAAHALAHIGLPGATGAVLIGLPAAVGLGVFCVGGALVIGALGKR
MSMEG_6045|M.smegmatis_MC2_155      VRNTAFAAHALAHIGLPGATGAALLGLPAVLGLGVFCVAGAVVIGALGKQ
                                                                                      

Rv2060|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2086|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5073|M.marinum_M               ARERDSVIGVVLAFGMGLAVLFIHLYPGRTGTSFALLTGQIVGVGYSGLT
MUL_4149|M.ulcerans_Agy99           ARERDSVIGVVLAFGMGLAVLFIHLYPGRTGTSFALLTGQIVGVGYSGLT
MLBr_00335|M.leprae_Br4923          ARERDSVIGVVLAFGLGLAVLFIHLYPGRTGTSLALLTGQIIDVGYSGLA
MAV_0581|M.avium_104                ARERDSVIGVVLAFGLGLAVLFIHLYPGRTATSFALLTGQIVGVGYTGLT
MAB_0575c|M.abscessus_ATCC_199      TKDRDSSIGVVMAFGLGLAVLFIHLYPGRTGTNFALLTGQIVGVGYSGLL
TH_1747|M.thermoresistible__bu      ARERDSAIGVVLAFGLGLAVLFIHLYPGRAGTSFALLTGQIVGVSYTGLA
Mflv_1456|M.gilvum_PYR-GCK          AADREVATGTVLAFATGLGLFFNSLATKNSSTLTNVLFGNLLAISGQQLL
Mvan_5318|M.vanbaalenii_PYR-1       AADREVATGTVLAFATGLGLFFNSLATRNSSTLTNVLFGNLLAITSEQLL
MSMEG_6045|M.smegmatis_MC2_155      AHDREVATGTVLALATGFGLFFNSLATKNSSTLTNVLFGNLLAITHEQLL
                                                                                      

Rv2060|M.tuberculosis_H37Rv         MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMGV
Mb2086|M.bovis_AF2122/97            MLTVVCLLVVTVLAICYRPLLFATVDPEVAAARGVPVRALGIVFAALMGV
MMAR_5073|M.marinum_M               MLALICVLVVAALAICYRPLLFATVDPEVAAARGVPVRTLSIVFAALVGV
MUL_4149|M.ulcerans_Agy99           MLALICVLVVAALAICYRPLLFATVDPEVAAARGVPVRTLSIVFVALVGV
MLBr_00335|M.leprae_Br4923          TLALVCLFVIAVLTTCYRPLLFATVDPEVAAACGVPVHALGIVFAALVGL
MAV_0581|M.avium_104                MLALVCLLVIAVLATCYRPLLFATVDPDVAAARGVPVHALGIVFAALVGV
MAB_0575c|M.abscessus_ATCC_199      MLVVVSMVVGAVLAVTYRPMLFATVDPDVAEARGVPVRALGIVFAALVGL
TH_1747|M.thermoresistible__bu      MLVAVTVAVVAVLAVSYRPLLFATVDPEVAAGRGVPVRALGIVFAALVGV
Mflv_1456|M.gilvum_PYR-GCK          SFFALLLLTAAGMAFIFRPLLFTSVNSRVAEAKGVPVRGLSVAFMVLLGL
Mvan_5318|M.vanbaalenii_PYR-1       SFFALLVLTAAGIAFIFRPLLFTSVNSKVAEAKGVPVRGLSIVFMVLLGL
MSMEG_6045|M.smegmatis_MC2_155      TFTALLLVLAAAIVFIYRPLLFASVNAQVAEAKGVPVRTLSVVFMVLLGV
                                     :  : :   : :.  :**:**::*:. ** . ****: *.:.* .*:*:

Rv2060|M.tuberculosis_H37Rv         VAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVGG
Mb2086|M.bovis_AF2122/97            VAAQAVQIVGALLVMSLLITPAAAAARVVVAPVAAIATSVVFAEVSAVGG
MMAR_5073|M.marinum_M               VAAQAVQIVGALLVMSLLITPAAAAARVVTAPAAAILTSVVFAEVAAVGG
MUL_4149|M.ulcerans_Agy99           VAAQAVQIVGALLVMSLLITPAAAAARVVTAPAAAILTSVVFAELAAVGG
MLBr_00335|M.leprae_Br4923          VAAQAVQVVGALLVMSLLITPAAAAAQVVASPVAAMVAAVIFAEVSAVGG
MAV_0581|M.avium_104                VAAQAVQIVGALLVMSLLITPAAAAARVVASPGAAMLASVAFAEVSALGG
MAB_0575c|M.abscessus_ATCC_199      TAAQGVQIVGALLVMSLLITPAAAAARITSSPARAIALSIVFAEIAAIGG
TH_1747|M.thermoresistible__bu      VAAQGVQIVGALLVMSLLITPAAAAVRVFVSPAATIAASVLFAAVSAVGG
Mflv_1456|M.gilvum_PYR-GCK          TVTMAVQAVGTLLLFALVVTPAATALMLTARPVLAMGLSAAIGLVSVWAG
Mvan_5318|M.vanbaalenii_PYR-1       TVTMAVQAVGTLLLFALVVTPAATALMVTARPVMAMAVSAVIGLVSVWAG
MSMEG_6045|M.smegmatis_MC2_155      AVTMAVQAVGTLLLFALVVTPAATAITLTAQPRLAMAISTVISLLSVWAG
                                    ..: .** **:**:::*::****:*  :   *  ::  :  :. ::. .*

Rv2060|M.tuberculosis_H37Rv         ILLSLAPGVPVSVFVATISFVIYLICWLLRRRR-------------
Mb2086|M.bovis_AF2122/97            ILLSLAPGVPVSVFVATISFVIYLICWLLRRRR-------------
MMAR_5073|M.marinum_M               IVLSLAPGVPVSVFVATISFLIYLICRLLGRHR-------------
MUL_4149|M.ulcerans_Agy99           IVLSLAPGVPVSVFVATISFLIYLICRLLGRHR-------------
MLBr_00335|M.leprae_Br4923          VVLSLAPGVPVSVFVATISFLIYLFCWLLGRHREVCA---------
MAV_0581|M.avium_104                IVLSLAPGVPVSVFVATISFLIYLACWLIGRRREAAT---------
MAB_0575c|M.abscessus_ATCC_199      IMLSLAPGVPISVFVTMIAVAIYLLCRLVGRYRHA-----------
TH_1747|M.thermoresistible__bu      IILSLAPGVPVSVFVTAISFAIYVICWVIGRYRHTSAA--------
Mflv_1456|M.gilvum_PYR-GCK          LVLSAMFNLPPSFVIVTIACAVWLVVWGGSRMPRRGRKEAVAQPIG
Mvan_5318|M.vanbaalenii_PYR-1       LAFSAMFNLPPSFVIVSIVCAVWLLVWAGCRVPVRA----------
MSMEG_6045|M.smegmatis_MC2_155      LVLSAVFNLPPSFVIVTIACVFWFVVWAANRARRSAVARP------
                                    : :*   .:* *..:. *   .:.      *